Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02781
(520 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q63810|CANB1_MOUSE Calcineurin B subunit isoform 1 (Prot... 179 3e-45
sp|P63098|CANB1_HUMAN Calcineurin B subunit isoform 1 (Prot... 179 3e-45
sp|Q24214|CANB2_DROME Calcineurin B subunit isoform 2 (Prot... 172 4e-43
sp|P48451|CANB1_DROME Calcineurin B subunit isoform 1 (Prot... 172 6e-43
sp|Q6CGE6|CANB_YARLI Calcineurin B subunit (Protein phospha... 157 1e-38
sp|Q63811|CANB2_MOUSE Calcineurin B subunit isoform 2 (Prot... 157 2e-38
sp|P28470|CANB2_RAT Calcineurin B subunit isoform 2 (Protei... 157 2e-38
sp|Q96LZ3|CANB2_HUMAN Calcineurin B subunit isoform 2 (Prot... 156 3e-38
sp|P87072|CANB_NEUCR Calcineurin B subunit (Protein phospha... 147 1e-35
sp|Q9HDE1|CANB_CRYNE Calcineurin B subunit (Protein phospha... 145 4e-35
>sp|Q63810|CANB1_MOUSE Calcineurin B subunit isoform 1 (Protein phosphatase 2B regulatory
subunit 1) (Protein phosphatase 3 regulatory subunit B
alpha isoform 1)
Length = 170
Score = 179 bits (455), Expect = 3e-45
Identities = 84/103 (81%), Positives = 98/103 (95%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD
Sbjct: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVDI 311
QLQQIVDKTI+ ADKDGDG+IS+EEFC+VV G+D+H KMVVD+
Sbjct: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170
Score = 33.1 bits (74), Expect = 0.41
Identities = 20/67 (29%), Positives = 31/67 (46%)
Frame = +3
Query: 87 FKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIMFADKDGDGKISYEEFCS 266
FK D+D G +S E +L + Q +V + I D DG+G++ ++EF
Sbjct: 27 FKKLDLDNSGSLSVEEFM---------SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77
Query: 267 VVSGMDV 287
VS V
Sbjct: 78 GVSQFSV 84
>sp|P63098|CANB1_HUMAN Calcineurin B subunit isoform 1 (Protein phosphatase 2B regulatory
subunit 1) (Protein phosphatase 3 regulatory subunit B
alpha isoform 1)
sp|P63099|CANB1_BOVIN Calcineurin B subunit isoform 1 (Protein phosphatase 2B regulatory
subunit 1) (Protein phosphatase 3 regulatory subunit B
alpha isoform 1)
sp|P63100|CANB1_RAT Calcineurin B subunit isoform 1 (Protein phosphatase 2B regulatory
subunit 1) (Protein phosphatase 3 regulatory subunit B
alpha isoform 1)
Length = 170
Score = 179 bits (455), Expect = 3e-45
Identities = 84/103 (81%), Positives = 98/103 (95%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD
Sbjct: 68 GEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDT 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVDI 311
QLQQIVDKTI+ ADKDGDG+IS+EEFC+VV G+D+H KMVVD+
Sbjct: 128 QLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170
Score = 33.1 bits (74), Expect = 0.41
Identities = 20/67 (29%), Positives = 31/67 (46%)
Frame = +3
Query: 87 FKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIMFADKDGDGKISYEEFCS 266
FK D+D G +S E +L + Q +V + I D DG+G++ ++EF
Sbjct: 27 FKKLDLDNSGSLSVEEFM---------SLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE 77
Query: 267 VVSGMDV 287
VS V
Sbjct: 78 GVSQFSV 84
>sp|Q24214|CANB2_DROME Calcineurin B subunit isoform 2 (Protein phosphatase 2B regulatory
subunit)
Length = 170
Score = 172 bits (436), Expect = 4e-43
Identities = 83/103 (80%), Positives = 93/103 (90%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDFKEFI G+SQFSVKG+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD
Sbjct: 68 GEVDFKEFIQGVSQFSVKGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDT 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVDI 311
QLQQIVDKTI FADKD DGKIS++EFCSVV D+H KMVVD+
Sbjct: 128 QLQQIVDKTIGFADKDEDGKISFDEFCSVVGNTDIHKKMVVDV 170
Score = 32.3 bits (72), Expect = 0.69
Identities = 19/67 (28%), Positives = 31/67 (46%)
Frame = +3
Query: 87 FKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIMFADKDGDGKISYEEFCS 266
F+ D+D G +S E +L + Q +V + I D DG+G++ ++EF
Sbjct: 27 FRKLDLDNSGALSVDEFM---------SLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQ 77
Query: 267 VVSGMDV 287
VS V
Sbjct: 78 GVSQFSV 84
>sp|P48451|CANB1_DROME Calcineurin B subunit isoform 1 (Protein phosphatase 2B regulatory
subunit)
Length = 170
Score = 172 bits (435), Expect = 6e-43
Identities = 82/103 (79%), Positives = 93/103 (90%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDFKEFI G+SQFSV+G+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD
Sbjct: 68 GEVDFKEFIQGVSQFSVRGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDT 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVDI 311
QLQQIVDKTI FADKD DGKIS++EFCSVV D+H KMVVD+
Sbjct: 128 QLQQIVDKTICFADKDEDGKISFDEFCSVVGNTDIHKKMVVDV 170
Score = 32.3 bits (72), Expect = 0.69
Identities = 19/67 (28%), Positives = 31/67 (46%)
Frame = +3
Query: 87 FKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIMFADKDGDGKISYEEFCS 266
F+ D+D G +S E +L + Q +V + I D DG+G++ ++EF
Sbjct: 27 FRKLDLDNSGALSIDEFM---------SLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQ 77
Query: 267 VVSGMDV 287
VS V
Sbjct: 78 GVSQFSV 84
>sp|Q6CGE6|CANB_YARLI Calcineurin B subunit (Protein phosphatase 2B regulatory subunit)
(Calcineurin regulatory subunit)
Length = 173
Score = 157 bits (398), Expect = 1e-38
Identities = 76/103 (73%), Positives = 91/103 (88%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
G+VDF+EFI+G+S FS KGNK+ KLRFAFK+YD+DRDG+ISNGELF VLK+MVGNNLKDA
Sbjct: 70 GDVDFQEFINGLSTFSTKGNKKEKLRFAFKVYDIDRDGYISNGELFIVLKMMVGNNLKDA 129
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVDI 311
QLQQIVDKTIM ADKDGDGKIS+EEF + V G +V+ M +D+
Sbjct: 130 QLQQIVDKTIMEADKDGDGKISFEEFEAQVGGTNVYQSMTLDL 172
>sp|Q63811|CANB2_MOUSE Calcineurin B subunit isoform 2 (Protein phosphatase 2B regulatory
subunit 2) (Protein phosphatase 3 regulatory subunit B
beta isoform)
Length = 179
Score = 157 bits (396), Expect = 2e-38
Identities = 76/101 (75%), Positives = 88/101 (87%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDF EFI G SQFSVKG++E KLRFAF+IYDMD DGFISNGELFQVLK+MVGNNLKD
Sbjct: 68 GEVDFHEFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDW 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVV 305
QLQQ+VDK+I+ DKDGDG+IS+EEF VV M++H K+VV
Sbjct: 128 QLQQLVDKSILVLDKDGDGRISFEEFSDVVKTMEIHKKLVV 168
>sp|P28470|CANB2_RAT Calcineurin B subunit isoform 2 (Protein phosphatase 2B regulatory
subunit 2) (Protein phosphatase 3 regulatory subunit B
beta isoform) (Calcineurin B-like protein) (CBLP)
Length = 176
Score = 157 bits (396), Expect = 2e-38
Identities = 76/101 (75%), Positives = 89/101 (88%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDF+EFI G SQFSVKG++E KLRFAF+IYDMD DGFISNGELFQVLK+MVGNNLKD
Sbjct: 68 GEVDFREFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDW 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVV 305
QLQQ+VDK+I+ DKDGDG+IS+EEF VV M++H K+VV
Sbjct: 128 QLQQLVDKSILVLDKDGDGRISFEEFRDVVRTMEIHKKLVV 168
>sp|Q96LZ3|CANB2_HUMAN Calcineurin B subunit isoform 2 (Protein phosphatase 2B regulatory
subunit 2) (Protein phosphatase 3 regulatory subunit B
beta isoform) (Calcineurin B-like protein) (CBLP)
(CNBII)
Length = 170
Score = 156 bits (394), Expect = 3e-38
Identities = 75/101 (74%), Positives = 89/101 (88%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
GEVDFKEFI G SQFSVKG++E KLRFAF IYDMD+DG+ISNGELFQVLK+MVGNNL D
Sbjct: 68 GEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDW 127
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVV 305
QLQQ+VDKTI+ DKDGDGKIS+EEF +VV +++H K+V+
Sbjct: 128 QLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVL 168
Score = 30.4 bits (67), Expect = 2.6
Identities = 17/58 (29%), Positives = 29/58 (50%)
Frame = +3
Query: 87 FKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIMFADKDGDGKISYEEF 260
FK D+D+ G +S E +L + + +V + I D DGDG++ ++EF
Sbjct: 27 FKKLDLDKSGSLSVEEFM---------SLPELRHNPLVRRVIDVFDTDGDGEVDFKEF 75
>sp|P87072|CANB_NEUCR Calcineurin B subunit (Protein phosphatase 2B regulatory subunit)
(Calcineurin regulatory subunit)
Length = 174
Score = 147 bits (372), Expect = 1e-35
Identities = 72/102 (70%), Positives = 84/102 (82%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
G+VDF+EF+ G+S FS KGNKE KLRFAFK+YD+DRDG+ISNGELF VLK+MVG+NLKD
Sbjct: 71 GDVDFQEFVSGLSAFSSKGNKEQKLRFAFKVYDIDRDGYISNGELFIVLKMMVGSNLKDQ 130
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVD 308
QLQQIVDKTIM AD D DGKIS+EEF +V DV M +D
Sbjct: 131 QLQQIVDKTIMEADLDKDGKISFEEFTKMVENTDVSMSMTLD 172
>sp|Q9HDE1|CANB_CRYNE Calcineurin B subunit (Protein phosphatase 2B regulatory subunit)
(Calcineurin regulatory subunit)
Length = 175
Score = 145 bits (367), Expect = 4e-35
Identities = 69/102 (67%), Positives = 85/102 (83%)
Frame = +3
Query: 3 GEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDA 182
G VDF+EF+ G+S FS KG ++ KLRFAFK+YDMDRDG+ISNGEL+ VLK MVGNNLKD
Sbjct: 71 GTVDFQEFVGGLSAFSSKGGRDEKLRFAFKVYDMDRDGYISNGELYLVLKQMVGNNLKDQ 130
Query: 183 QLQQIVDKTIMFADKDGDGKISYEEFCSVVSGMDVHTKMVVD 308
QLQQIVDKTIM ADKDGDGK+S+EEF +V+ D+ +M ++
Sbjct: 131 QLQQIVDKTIMEADKDGDGKLSFEEFTQMVASTDIVKQMTLE 172
Score = 29.6 bits (65), Expect = 4.5
Identities = 23/79 (29%), Positives = 35/79 (44%)
Frame = +3
Query: 39 SQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIMF 218
S FS G + +L+ F D D G I E Q+ +I NN + + I
Sbjct: 16 SNFS--GPELMRLKKRFMKLDKDGSGSIDKDEFLQIPQI--ANN-------PLAHRMIAI 64
Query: 219 ADKDGDGKISYEEFCSVVS 275
D+DG G + ++EF +S
Sbjct: 65 FDEDGSGTVDFQEFVGGLS 83
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,825,890
Number of Sequences: 369166
Number of extensions: 1158461
Number of successful extensions: 3849
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3130
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3533
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3403581975
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)