Planaria EST Database


DrC_02774

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02774
         (759 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P30531|SC6A1_HUMAN  Sodium- and chloride-dependent GABA t...   299   6e-81
sp|P23978|SC6A1_RAT  Sodium- and chloride-dependent GABA tra...   298   8e-81
sp|P48057|SC6A1_MUSCO  Sodium- and chloride-dependent GABA t...   295   7e-80
sp|O18875|SC6A8_BOVIN  Sodium- and chloride-dependent creati...   252   7e-67
sp|P28570|SC6A8_RAT  Sodium- and chloride-dependent creatine...   251   1e-66
sp|P48029|SC6A8_HUMAN  Sodium- and chloride-dependent creati...   251   1e-66
sp|P31661|SC6A8_RABIT  Sodium- and chloride-dependent creati...   249   4e-66
sp|Q91502|SC6A8_TORMA  Creatine transporter                       248   2e-65
sp|P48066|S6A11_HUMAN  Sodium- and chloride-dependent GABA t...   247   3e-65
sp|P31647|S6A11_RAT  Sodium- and chloride-dependent GABA tra...   246   5e-65
>sp|P30531|SC6A1_HUMAN Sodium- and chloride-dependent GABA transporter 1
          Length = 599

 Score =  299 bits (765), Expect = 6e-81
 Identities = 135/250 (54%), Positives = 181/250 (72%)
 Frame = +3

Query: 9    EEGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVG 188
            +EGI+FY+ P+  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN ++NN +RD++IV 
Sbjct: 265  KEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVC 324

Query: 189  VVNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXX 368
             +N+ TS+FAGFV+FS++GFMAH           SG GL FL YP A+ QLP S +W+  
Sbjct: 325  CINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAIL 384

Query: 369  XXXXXXXXXXDSQFCTLEGFVTAIIDEWPNKFRNHRKLLLFVVCVVSYLIGILMVTQGGA 548
                      DSQFCT+EGF+TA++DE+P   RN R+L +  VC++SYLIG+  +TQGG 
Sbjct: 385  FFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGI 444

Query: 549  YVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLICC 728
            YVF+LFD+YSASGM+LLFL+F EC++ SW YG+NRF  + ++M+G +   WWK CW    
Sbjct: 445  YVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFT 504

Query: 729  PLVCMFVFIF 758
            P++   VFIF
Sbjct: 505  PIIVAGVFIF 514
>sp|P23978|SC6A1_RAT Sodium- and chloride-dependent GABA transporter 1
 sp|P31648|SC6A1_MOUSE Sodium- and chloride-dependent GABA transporter 1
          Length = 599

 Score =  298 bits (764), Expect = 8e-81
 Identities = 135/250 (54%), Positives = 181/250 (72%)
 Frame = +3

Query: 9    EEGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVG 188
            +EGI+FY+ P+  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN ++NN +RD++IV 
Sbjct: 265  KEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVC 324

Query: 189  VVNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXX 368
             +N+ TS+FAGFV+FS++GFMAH           SG GL FL YP A+ QLP S +W+  
Sbjct: 325  CINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAIL 384

Query: 369  XXXXXXXXXXDSQFCTLEGFVTAIIDEWPNKFRNHRKLLLFVVCVVSYLIGILMVTQGGA 548
                      DSQFCT+EGF+TA++DE+P   RN R+L +  VC+VSYLIG+  +TQGG 
Sbjct: 385  FFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIVSYLIGLSNITQGGI 444

Query: 549  YVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLICC 728
            YVF+LFD+YSASGM+LLFL+F EC++ SW YG+NRF  + ++M+G +   WWK CW    
Sbjct: 445  YVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFT 504

Query: 729  PLVCMFVFIF 758
            P++   VF+F
Sbjct: 505  PIIVAGVFLF 514
>sp|P48057|SC6A1_MUSCO Sodium- and chloride-dependent GABA transporter 1
          Length = 598

 Score =  295 bits (756), Expect = 7e-80
 Identities = 134/250 (53%), Positives = 180/250 (72%)
 Frame = +3

Query: 9    EEGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVG 188
            +EGI+FY+ P+  KL +S+VWLD ATQIFFSYGLGLG+ IALGSYN ++NN +RD++IV 
Sbjct: 264  KEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVC 323

Query: 189  VVNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXX 368
             +N+ TS+FAGFV+FS++GFMAH           SG GL FL YP A+ QLP S +W+  
Sbjct: 324  CINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAIL 383

Query: 369  XXXXXXXXXXDSQFCTLEGFVTAIIDEWPNKFRNHRKLLLFVVCVVSYLIGILMVTQGGA 548
                      DSQFCT+EGF+TA++DE+    RN R+L +  VC+VSYLIG+  +TQGG 
Sbjct: 384  FFSMLLMLGIDSQFCTVEGFITALVDEYSRLLRNRRELFIAAVCIVSYLIGLSNITQGGI 443

Query: 549  YVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLICC 728
            YVF+LFD+YSASGM+LLFL+F EC++ SW YG+NRF  + ++M+G +   WWK CW    
Sbjct: 444  YVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFT 503

Query: 729  PLVCMFVFIF 758
            P++   VF+F
Sbjct: 504  PIIVAGVFLF 513
>sp|O18875|SC6A8_BOVIN Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine
            transporter 1) (Solute carrier family 6 member 8)
          Length = 635

 Score =  252 bits (644), Expect = 7e-67
 Identities = 118/251 (47%), Positives = 164/251 (65%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            +GI++YLKPD SKL   +VW+D  TQIFFSY +GLG   ALGSYN++NNNC++DA+I+ +
Sbjct: 287  DGIIYYLKPDWSKLASPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILAL 346

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            +N+ TS FAGFVVFS++GFMA            SG GL F+ YP A+  +P + +W+   
Sbjct: 347  INSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALF 406

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNK--FRNHRKLLLFVVCVVSYLIGILMVTQGG 545
                     DSQF  +EGF+T ++D  P    FR  R++ + + C + ++I + MVT GG
Sbjct: 407  FFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCTICFVIDLSMVTDGG 466

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             YVF+LFD+YSASG  LL+  F EC+  +W YG +RFM D   M+G++   W K+CW   
Sbjct: 467  MYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDVACMIGYRPCPWMKWCWSFF 526

Query: 726  CPLVCMFVFIF 758
             PLVCM +FIF
Sbjct: 527  TPLVCMGIFIF 537
>sp|P28570|SC6A8_RAT Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine
            transporter 1) (CHOT1) (Solute carrier family 6 member 8)
          Length = 635

 Score =  251 bits (641), Expect = 1e-66
 Identities = 118/251 (47%), Positives = 164/251 (65%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            +GI++YLKPD SKL   +VW+D  TQIFFSY +GLG   ALGSYN++NNNC++DA+I+ +
Sbjct: 287  DGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILAL 346

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            +N+ TS FAGFVVFS++GFMA            SG GL F+ YP A+  +P + +W+   
Sbjct: 347  INSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALF 406

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNK--FRNHRKLLLFVVCVVSYLIGILMVTQGG 545
                     DSQF  +EGF+T ++D  P    FR  R++ + + C + ++I + MVT GG
Sbjct: 407  FFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGG 466

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             YVF+LFD+YSASG  LL+  F EC+  +W YG +RFM D   M+G++   W K+CW   
Sbjct: 467  MYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFF 526

Query: 726  CPLVCMFVFIF 758
             PLVCM +FIF
Sbjct: 527  TPLVCMGIFIF 537
>sp|P48029|SC6A8_HUMAN Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine
            transporter 1) (Solute carrier family 6 member 8)
          Length = 635

 Score =  251 bits (641), Expect = 1e-66
 Identities = 118/251 (47%), Positives = 164/251 (65%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            +GI++YLKPD SKL   +VW+D  TQIFFSY +GLG   ALGSYN++NNNC++DA+I+ +
Sbjct: 287  DGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILAL 346

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            +N+ TS FAGFVVFS++GFMA            SG GL F+ YP A+  +P + +W+   
Sbjct: 347  INSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALF 406

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNK--FRNHRKLLLFVVCVVSYLIGILMVTQGG 545
                     DSQF  +EGF+T ++D  P    FR  R++ + + C + ++I + MVT GG
Sbjct: 407  FFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGG 466

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             YVF+LFD+YSASG  LL+  F EC+  +W YG +RFM D   M+G++   W K+CW   
Sbjct: 467  MYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFF 526

Query: 726  CPLVCMFVFIF 758
             PLVCM +FIF
Sbjct: 527  TPLVCMGIFIF 537
>sp|P31661|SC6A8_RABIT Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine
            transporter 1) (Solute carrier family 6 member 8)
          Length = 635

 Score =  249 bits (637), Expect = 4e-66
 Identities = 117/251 (46%), Positives = 164/251 (65%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            +GI++YLKPD SKL+  +VW+D  TQIFFSY +GLG   ALGSYN++NNNC++DA+I+ +
Sbjct: 287  DGIIYYLKPDWSKLRSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILAL 346

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            +N+ TS FAGFVVFS++GFMA            SG GL F+ YP A+  +P + +W+   
Sbjct: 347  INSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALF 406

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNK--FRNHRKLLLFVVCVVSYLIGILMVTQGG 545
                     DSQF  +EGF+T ++D  P    FR  R++ + + C + ++I + MV   G
Sbjct: 407  FFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVQMAG 466

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             YVF+LFD+YSASG  LL+  F EC+A +W YG +RFM D   M+G++   W K+CW   
Sbjct: 467  MYVFQLFDYYSASGTTLLWQAFWECVAVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFF 526

Query: 726  CPLVCMFVFIF 758
             PLVCM +FIF
Sbjct: 527  TPLVCMGIFIF 537
>sp|Q91502|SC6A8_TORMA Creatine transporter
          Length = 611

 Score =  248 bits (632), Expect = 2e-65
 Identities = 118/251 (47%), Positives = 170/251 (67%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            +GI++YL+PD  KL E++VW+D  TQIFFSY +GLGT  ALGSYN+ +N+C++DA I+ +
Sbjct: 264  QGIVYYLQPDWGKLGEAQVWIDAGTQIFFSYAIGLGTLTALGSYNQLHNDCYKDAFILSL 323

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            VN++TS FAG VVFS++GFMA            SG GL F+ YP A+  +P   VW+   
Sbjct: 324  VNSATSFFAGLVVFSILGFMAVEEGVDISVVAESGPGLAFIAYPKAVTLMPFPQVWAVLF 383

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNK--FRNHRKLLLFVVCVVSYLIGILMVTQGG 545
                      SQF  +EGFVTAI+D WP+K  FR  R++++ +V  +S+LI + M+T+GG
Sbjct: 384  FIMLLCLGLGSQFVGVEGFVTAILDLWPSKFSFRYLREVVVAMVICLSFLIDLSMITEGG 443

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             Y+F++FD+YSASG  LL+  F EC+A +W YG +R++ D   MLG++ +   K+CW + 
Sbjct: 444  MYIFQIFDYYSASGTTLLWTAFWECVAVAWVYGGDRYLDDLAWMLGYRPWALVKWCWSVI 503

Query: 726  CPLVCMFVFIF 758
             PLVCM +F F
Sbjct: 504  TPLVCMGIFTF 514
>sp|P48066|S6A11_HUMAN Sodium- and chloride-dependent GABA transporter 3
          Length = 632

 Score =  247 bits (630), Expect = 3e-65
 Identities = 116/251 (46%), Positives = 161/251 (64%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            EGI FYL PD+S+L + +VW+D  TQIFFSY + LG   ALGSYN YNNNC+RD +++  
Sbjct: 280  EGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCC 339

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            +N+ TS  AGF +FSV+GFMA+           SG GL F+ YP A+  +P S +W+   
Sbjct: 340  LNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLF 399

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNKFRN--HRKLLLFVVCVVSYLIGILMVTQGG 545
                     DSQF  +E  VTA++D +P  FR    R+LL+  + V+SY +G++M+T+GG
Sbjct: 400  FMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGG 459

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             Y+F+LFD Y+ASGM LLF+   ECI   W YG NRF  + E M+G++     K+CW+I 
Sbjct: 460  MYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIM 519

Query: 726  CPLVCMFVFIF 758
             P +C  +FIF
Sbjct: 520  TPGICAGIFIF 530
>sp|P31647|S6A11_RAT Sodium- and chloride-dependent GABA transporter 3
          Length = 627

 Score =  246 bits (628), Expect = 5e-65
 Identities = 114/251 (45%), Positives = 160/251 (63%), Gaps = 2/251 (0%)
 Frame = +3

Query: 12   EGIMFYLKPDISKLKESKVWLDGATQIFFSYGLGLGTHIALGSYNKYNNNCHRDALIVGV 191
            EGI FYL PD+S+L + +VW+D  TQIFFSY + LG   ALGSYN YNNNC+RD +++  
Sbjct: 275  EGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCC 334

Query: 192  VNASTSLFAGFVVFSVMGFMAHXXXXXXXXXXXSGQGLIFLVYPSALAQLPGSAVWSXXX 371
            +N+ TS  AGF +FSV+GFMA+           SG GL F+ YP A+  +P S +W+   
Sbjct: 335  LNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLF 394

Query: 372  XXXXXXXXXDSQFCTLEGFVTAIIDEWPNKFRN--HRKLLLFVVCVVSYLIGILMVTQGG 545
                     DSQF  +E  VTA++D +P  FR    R+LL+  + +VSY +G++M+T+GG
Sbjct: 395  FMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIVSYFLGLVMLTEGG 454

Query: 546  AYVFRLFDHYSASGMALLFLIFCECIAFSWCYGINRFMKDCEKMLGFKLFRWWKFCWLIC 725
             Y+F+LFD Y+ASGM LLF+   EC+   W YG NRF  + E M+G++     K+CW + 
Sbjct: 455  MYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVV 514

Query: 726  CPLVCMFVFIF 758
             P +C  +FIF
Sbjct: 515  TPGICAGIFIF 525
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,541,728
Number of Sequences: 369166
Number of extensions: 1783429
Number of successful extensions: 4450
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4148
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4338
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)