Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02710
(844 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55162|HEM_DROME Membrane-associated protein Hem (dHem-2) 107 4e-23
sp|P28660|NCKP1_MOUSE Nck-associated protein 1 (NAP 1) (p12... 103 6e-22
sp|P55161|NCKP1_RAT Nck-associated protein 1 (NAP 1) (p125N... 103 6e-22
sp|Q9Y2A7|NCKP1_HUMAN Nck-associated protein 1 (NAP 1) (p12... 103 8e-22
sp|P55160|NCKPL_HUMAN Nck-associated protein 1-like (Membra... 94 4e-19
sp|P55163|GEX3_CAEEL Membrane-associated protein gex-3 77 5e-14
sp|P79098|AMPN_BOVIN Aminopeptidase N (bAPN) (Alanyl aminop... 34 0.58
sp|P28699|RARG_XENLA Retinoic acid receptor gamma (RAR-gamma) 32 2.9
sp|Q90273|RARG2_BRARE Retinoic acid receptor gamma-2 (RAR-g... 31 3.7
sp|Q91392|RARG_BRARE Retinoic acid receptor gamma (RAR-gamm... 31 4.9
>sp|P55162|HEM_DROME Membrane-associated protein Hem (dHem-2)
Length = 1126
Score = 107 bits (267), Expect = 4e-23
Identities = 65/222 (29%), Positives = 102/222 (45%)
Frame = +2
Query: 11 DMDLKSFRDVRLDWFRLQTFLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFLDKI 190
D +L FR RLDWFRLQT++S + ++ ++SM+ HT VDNL+ L +
Sbjct: 477 DNELFYFRPFRLDWFRLQTYMSVGKAALRIAEHAELARLLDSMVFHTRVVDNLDEILVET 536
Query: 191 SSLQFLCFHRSKLNEWFEMNLKITAQHRYATIFPRLCGYFINNCQPSCPEDFNEILRSSI 370
S L CF+ ++ F M L+ AQ+RY FP +C +F N CPE+ + I S+
Sbjct: 537 SDLSIFCFYNKMFDDQFHMCLEFPAQNRYIIAFPLICSHFQNCTHEMCPEERHHIRERSL 596
Query: 371 EMGHAFLSRICQELCKLLAEMVKSHFDLNSLTQPTSAVDYYRSHLSRKSKDEATGHGKND 550
+ + FL + +E ++ + + P +RK KD++ +D
Sbjct: 597 SVVNIFLEEMAKEAKNIITTICDEQCTMADALLPKHCAKILSVQSARKKKDKSKSKHFDD 656
Query: 551 NKIVLSPLPGVESKPKDITVSSKFDMELMALNQLATGLNSRP 676
+ PG ES K + D MAL +L +N P
Sbjct: 657 IR-----KPGDESYRKTREDLTTMDKLHMALTELCFAINYCP 693
>sp|P28660|NCKP1_MOUSE Nck-associated protein 1 (NAP 1) (p125Nap1) (Membrane-associated
protein HEM-2) (Brain protein H19) (MH19)
Length = 1128
Score = 103 bits (257), Expect = 6e-22
Identities = 62/222 (27%), Positives = 106/222 (47%)
Frame = +2
Query: 11 DMDLKSFRDVRLDWFRLQTFLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFLDKI 190
D ++ FR +RLDWFRLQ + S + + MN++I HT VD+L L +
Sbjct: 477 DGEVFDFRGMRLDWFRLQAYTSVSKASLSLADHRELGKMMNTIIFHTKMVDSLVEMLVET 536
Query: 191 SSLQFLCFHRSKLNEWFEMNLKITAQHRYATIFPRLCGYFINNCQPSCPEDFNEILRSSI 370
S L CF+ + F+ L++ +Q RY+ FP LC +F++ CPE+ + I S+
Sbjct: 537 SDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSL 596
Query: 371 EMGHAFLSRICQELCKLLAEMVKSHFDLNSLTQPTSAVDYYRSHLSRKSKDEATGHGKND 550
+ + FL + ++ L+ ++ L+ P +++KSK + G+ +
Sbjct: 597 SLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPE 656
Query: 551 NKIVLSPLPGVESKPKDITVSSKFDMELMALNQLATGLNSRP 676
+ PGVES K+ V + D AL++L +N P
Sbjct: 657 RE-----KPGVESMRKNRLVVTNLDKLHTALSELCFSINYVP 693
>sp|P55161|NCKP1_RAT Nck-associated protein 1 (NAP 1) (p125Nap1) (Membrane-associated
protein HEM-2)
Length = 1128
Score = 103 bits (257), Expect = 6e-22
Identities = 62/222 (27%), Positives = 106/222 (47%)
Frame = +2
Query: 11 DMDLKSFRDVRLDWFRLQTFLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFLDKI 190
D ++ FR +RLDWFRLQ + S + + MN++I HT VD+L L +
Sbjct: 477 DGEVFDFRGMRLDWFRLQAYTSVSKASLSLADHRELGKMMNTIIFHTKMVDSLVEMLVET 536
Query: 191 SSLQFLCFHRSKLNEWFEMNLKITAQHRYATIFPRLCGYFINNCQPSCPEDFNEILRSSI 370
S L CF+ + F+ L++ +Q RY+ FP LC +F++ CPE+ + I S+
Sbjct: 537 SDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSL 596
Query: 371 EMGHAFLSRICQELCKLLAEMVKSHFDLNSLTQPTSAVDYYRSHLSRKSKDEATGHGKND 550
+ + FL + ++ L+ ++ L+ P +++KSK + G+ +
Sbjct: 597 SLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPE 656
Query: 551 NKIVLSPLPGVESKPKDITVSSKFDMELMALNQLATGLNSRP 676
+ PGVES K+ V + D AL++L +N P
Sbjct: 657 RE-----KPGVESMRKNRLVVTNLDKLHTALSELCFSINYVP 693
>sp|Q9Y2A7|NCKP1_HUMAN Nck-associated protein 1 (NAP 1) (p125Nap1) (Membrane-associated
protein HEM-2)
Length = 1128
Score = 103 bits (256), Expect = 8e-22
Identities = 62/222 (27%), Positives = 106/222 (47%)
Frame = +2
Query: 11 DMDLKSFRDVRLDWFRLQTFLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFLDKI 190
D ++ FR +RLDWFRLQ + S + + MN++I HT VD+L L +
Sbjct: 477 DGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVET 536
Query: 191 SSLQFLCFHRSKLNEWFEMNLKITAQHRYATIFPRLCGYFINNCQPSCPEDFNEILRSSI 370
S L CF+ + F+ L++ +Q RY+ FP LC +F++ CPE+ + I S+
Sbjct: 537 SDLSIFCFYSRAFEKMFQQCLELPSQSRYSIAFPLLCTHFMSCTHELCPEERHHIGDRSL 596
Query: 371 EMGHAFLSRICQELCKLLAEMVKSHFDLNSLTQPTSAVDYYRSHLSRKSKDEATGHGKND 550
+ + FL + ++ L+ ++ L+ P +++KSK + G+ +
Sbjct: 597 SLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPE 656
Query: 551 NKIVLSPLPGVESKPKDITVSSKFDMELMALNQLATGLNSRP 676
+ PGVES K+ V + D AL++L +N P
Sbjct: 657 RE-----KPGVESMRKNRLVVTNLDKLHTALSELCFSINYVP 693
>sp|P55160|NCKPL_HUMAN Nck-associated protein 1-like (Membrane-associated protein HEM-1)
(Hematopoietic protein 1)
Length = 1127
Score = 94.4 bits (233), Expect = 4e-19
Identities = 53/213 (24%), Positives = 98/213 (46%)
Frame = +2
Query: 29 FRDVRLDWFRLQTFLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFLDKISSLQFL 208
F +RLDWFRLQ + S + +N MN ++ H+ +D++E L + S L
Sbjct: 482 FSGLRLDWFRLQAYHSVAKAPLHLHENPDLAKVMNLIVFHSRMLDSVEKLLVETSDLSTF 541
Query: 209 CFHRSKLNEWFEMNLKITAQHRYATIFPRLCGYFINNCQPSCPEDFNEILRSSIEMGHAF 388
CFH + F M L+ +A RYA FP +C +F++ CPE++ + + ++F
Sbjct: 542 CFHLRIFEKMFAMTLEESAMLRYAIAFPLICAHFVHCTHEMCPEEYPHLKNHGLHHCNSF 601
Query: 389 LSRICQELCKLLAEMVKSHFDLNSLTQPTSAVDYYRSHLSRKSKDEATGHGKNDNKIVLS 568
L + ++ + E+ +L+ P ++K++ + K + +
Sbjct: 602 LEELAKQTSNCVLEICAEQRNLSEQLLPKHCATTISKAKNKKTRKQRQTPRKGEPE---R 658
Query: 569 PLPGVESKPKDITVSSKFDMELMALNQLATGLN 667
PG ES K+ ++ + D + L +LA +N
Sbjct: 659 DKPGAESHRKNRSIVTNMDKLHLNLTELALTMN 691
>sp|P55163|GEX3_CAEEL Membrane-associated protein gex-3
Length = 1141
Score = 77.4 bits (189), Expect = 5e-14
Identities = 63/243 (25%), Positives = 110/243 (45%), Gaps = 5/243 (2%)
Frame = +2
Query: 2 LSTDMDLKSFRDVRLDWFRLQTFLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFL 181
+++D DL++ +RLDWFR Q + S S F ++ +MN+ + H +D + L
Sbjct: 474 INSDTDLRA---LRLDWFRFQAWTSAARSHFQLSRHKKLAIYMNTSVFHLKMIDLQDEML 530
Query: 182 DKISSLQFLCFHRSKLNEWFEMN-LKITAQHRYATIFPRLCGYFINNCQPSCPEDFNEIL 358
+ S L CF+ KL E +N L++ AQ RY F RL +F + CPE+ I
Sbjct: 531 RETSDLSLYCFY-PKLAEKHWLNCLQLPAQARYVLSFARLAAHFTSALHDMCPEEKAFIT 589
Query: 359 RSSIEMGHAFLSRICQELCKLLAEMVKSHFDL-NSLTQPTSAVDYYRSHLSRKSKDEATG 535
++ ++ + C++L +L ++ + F L +T AV + +K +A
Sbjct: 590 EKALAQCNSVIEETCKQLSYILEKVAEHEFGLAYQMTPSAVAVRVVAQVVQQKGSGKAAA 649
Query: 536 HGKNDNKIVLSPLPGVESKPKD---ITVSSKFDMELMALNQLATGLNSRPIYINNRPLQP 706
+ + G ES D +T+ K L+ ++ A G + R IY+ + P
Sbjct: 650 AAAAAARDYF--IAGEESYRVDRQALTMPDKLQTTLLEIS-AALGAH-RQIYVADHTFAP 705
Query: 707 SQY 715
Y
Sbjct: 706 RTY 708
>sp|P79098|AMPN_BOVIN Aminopeptidase N (bAPN) (Alanyl aminopeptidase) (Microsomal
aminopeptidase) (Aminopeptidase M) (CD13)
Length = 234
Score = 33.9 bits (76), Expect = 0.58
Identities = 23/95 (24%), Positives = 34/95 (35%)
Frame = +2
Query: 68 FLSNINSKFPWQQNVPFINFMNSMILHTNFVDNLENFLDKISSLQFLCFHRSKLNEWFEM 247
FL N PWQ V +N+ M T ++N+L FL F N W E+
Sbjct: 80 FLKNEMEYMPWQAAVSSLNYFKLMFDRTEVYGPMQNYLKNQVEPIFLYFENLTKN-WTEI 138
Query: 248 NLKITAQHRYATIFPRLCGYFINNCQPSCPEDFNE 352
+ Q+ C + C+ FN+
Sbjct: 139 PENLMDQYSEINAISTACSNGLPKCEELAKTLFNQ 173
>sp|P28699|RARG_XENLA Retinoic acid receptor gamma (RAR-gamma)
Length = 476
Score = 31.6 bits (70), Expect = 2.9
Identities = 20/50 (40%), Positives = 27/50 (54%)
Frame = -2
Query: 210 QRNCKELILSRKFSRLSTKFVCKIIEFIKLMKGTFCCQGNFELILDKNVC 61
QR +L L KFS LSTK + KI+EF K + G ++ L K+ C
Sbjct: 239 QRVQLDLGLWDKFSELSTKCIIKIVEFAKRLPGFTTLTIADQITLLKSAC 288
>sp|Q90273|RARG2_BRARE Retinoic acid receptor gamma-2 (RAR-gamma-2)
Length = 367
Score = 31.2 bits (69), Expect = 3.7
Identities = 18/45 (40%), Positives = 25/45 (55%)
Frame = -2
Query: 195 ELILSRKFSRLSTKFVCKIIEFIKLMKGTFCCQGNFELILDKNVC 61
+L L KFS LSTK + KI+EF K + G ++ L K+ C
Sbjct: 211 DLGLWDKFSELSTKCIIKIVEFAKALPGFTTLTIADQITLLKSAC 255
>sp|Q91392|RARG_BRARE Retinoic acid receptor gamma (RAR-gamma) (ZRAR gamma)
Length = 499
Score = 30.8 bits (68), Expect = 4.9
Identities = 18/45 (40%), Positives = 25/45 (55%)
Frame = -2
Query: 195 ELILSRKFSRLSTKFVCKIIEFIKLMKGTFCCQGNFELILDKNVC 61
+L L KFS LSTK + KI+EF K + G ++ L K+ C
Sbjct: 211 DLGLWDKFSELSTKCIIKIVEFAKRLPGFTTLTIADQITLLKSAC 255
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,848,485
Number of Sequences: 369166
Number of extensions: 1803557
Number of successful extensions: 4342
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4206
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4341
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)