Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02701
(639 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P30415|NKTR_MOUSE NK-tumor recognition protein (Natural-... 165 8e-41
sp|P30414|NKTR_HUMAN NK-tumor recognition protein (Natural-... 163 3e-40
sp|Q9P3X9|PPID_NEUCR 41 kDa peptidyl-prolyl cis-trans isome... 163 4e-40
sp|O55035|PPIG_RAT Peptidyl-prolyl cis-trans isomerase G (P... 163 4e-40
sp|Q13427|PPIG_HUMAN Peptidyl-prolyl cis-trans isomerase G ... 162 5e-40
sp|P34790|CYP1_ARATH Peptidyl-prolyl cis-trans isomerase (P... 160 3e-39
sp|P73789|PPI2_SYNY3 Peptidyl-prolyl cis-trans isomerase sl... 158 1e-38
sp|P52009|CYP1_CAEEL Peptidyl-prolyl cis-trans isomerase 1 ... 158 1e-38
sp|P52010|CYP2_CAEEL Peptidyl-prolyl cis-trans isomerase 2 ... 157 2e-38
sp|P52015|CYP7_CAEEL Peptidyl-prolyl cis-trans isomerase 7 ... 155 6e-38
>sp|P30415|NKTR_MOUSE NK-tumor recognition protein (Natural-killer cells
cyclophilin-related protein) (NK-TR protein)
Length = 1453
Score = 165 bits (418), Expect = 8e-41
Identities = 84/176 (47%), Positives = 115/176 (65%), Gaps = 1/176 (0%)
Frame = +1
Query: 70 HMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFYR 249
H +IEI+ EP G + +L++DI PKTC+NF LC+GEKG K KL Y+ + F+R
Sbjct: 10 HFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGK---KLCYKGSTFHR 66
Query: 250 LVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFIT 429
+V N IQGGD G G GGESIYG F+DE+F +KHDR +LSMANRG+HTN SQFFIT
Sbjct: 67 VVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFIT 126
Query: 430 LTPGTWMDTRYVAFGAIIEGSETLKKMEAVPT-MNERPVKNIKIKDAKVVEPKLAE 594
P +D +V FG +I G E ++++E + T RP ++++ D V+ KL +
Sbjct: 127 TKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTK 182
>sp|P30414|NKTR_HUMAN NK-tumor recognition protein (Natural-killer cells
cyclophilin-related protein) (NK-TR protein)
Length = 1462
Score = 163 bits (413), Expect = 3e-40
Identities = 83/173 (47%), Positives = 113/173 (65%), Gaps = 1/173 (0%)
Frame = +1
Query: 70 HMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFYR 249
H +IEI+ EP G + +L++DI PKTC+NF LC+GEKG K KL Y+ + F+R
Sbjct: 10 HFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGK---KLCYKGSTFHR 66
Query: 250 LVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFIT 429
+V N IQGGD G G GGESIYG F+DE+F +KHDR +LSMANRG+HTN SQFFIT
Sbjct: 67 VVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFIT 126
Query: 430 LTPGTWMDTRYVAFGAIIEGSETLKKMEAVPT-MNERPVKNIKIKDAKVVEPK 585
P +D +V FG +I G E ++++E + T RP ++++ D V+ K
Sbjct: 127 TKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATK 179
>sp|Q9P3X9|PPID_NEUCR 41 kDa peptidyl-prolyl cis-trans isomerase (PPIase) (Rotamase)
(Cyclophilin-41) (CYP-41)
Length = 375
Score = 163 bits (412), Expect = 4e-40
Identities = 80/166 (48%), Positives = 108/166 (65%)
Frame = +1
Query: 67 IHMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFY 246
+ +I I + AG + ELYNDIVPKT ENFRALCTGEKG K + LHY+ + F+
Sbjct: 14 VFFDITIGGKAAGRIVFELYNDIVPKTAENFRALCTGEKGVGKLGK----PLHYKGSTFH 69
Query: 247 RLVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFI 426
R++ IQGGD G G+GGESIYG FEDE+F +KHDR +LSMAN G TN SQFF+
Sbjct: 70 RVIKQFMIQGGDFTAGNGTGGESIYGAKFEDENFQLKHDRPFLLSMANAGPGTNGSQFFV 129
Query: 427 TLTPGTWMDTRYVAFGAIIEGSETLKKMEAVPTMNERPVKNIKIKD 564
T P +D ++V FG ++ G ++++E + T ++P K+ I D
Sbjct: 130 TTVPTPHLDGKHVVFGEVLSGKSVVRQIENLKTQGDKPTKDAVIAD 175
>sp|O55035|PPIG_RAT Peptidyl-prolyl cis-trans isomerase G (Peptidyl-prolyl isomerase G)
(PPIase G) (Rotamase G) (Cyclophilin G) (Matrin
cyclophilin) (Matrin-cyp)
Length = 752
Score = 163 bits (412), Expect = 4e-40
Identities = 81/171 (47%), Positives = 112/171 (65%), Gaps = 1/171 (0%)
Frame = +1
Query: 76 EIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFYRLV 255
+I I+ +PAG + EL++D+ PKTCENFR LCTGEKG K + LHY++ +F+R+V
Sbjct: 13 DIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKP---LHYKSCLFHRVV 69
Query: 256 PNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLT 435
+ +QGGD G G GGESIYG FEDESFA+KH++ +LSMANRG+ TN SQFFIT
Sbjct: 70 KDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTK 129
Query: 436 PGTWMDTRYVAFGAIIEGSETLKKMEAVPT-MNERPVKNIKIKDAKVVEPK 585
P +D +V FG +I G E ++++E T +P ++I + PK
Sbjct: 130 PTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELVPK 180
>sp|Q13427|PPIG_HUMAN Peptidyl-prolyl cis-trans isomerase G (Peptidyl-prolyl isomerase G)
(PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating
RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp)
(SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10)
Length = 754
Score = 162 bits (411), Expect = 5e-40
Identities = 81/171 (47%), Positives = 112/171 (65%), Gaps = 1/171 (0%)
Frame = +1
Query: 76 EIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFYRLV 255
+I I+ +PAG + EL++D+ PKTCENFR LCTGEKG K + LHY++ +F+R+V
Sbjct: 13 DIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKP---LHYKSCLFHRVV 69
Query: 256 PNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFITLT 435
+ +QGGD G G GGESIYG FEDESFA+KH++ +LSMANRG+ TN SQFFIT
Sbjct: 70 KDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTK 129
Query: 436 PGTWMDTRYVAFGAIIEGSETLKKMEAVPT-MNERPVKNIKIKDAKVVEPK 585
P +D +V FG +I G E ++++E T +P ++I + PK
Sbjct: 130 PTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPK 180
>sp|P34790|CYP1_ARATH Peptidyl-prolyl cis-trans isomerase (PPIase) (Rotamase)
(Cyclophilin) (Cyclosporin A-binding protein)
Length = 172
Score = 160 bits (404), Expect = 3e-39
Identities = 77/166 (46%), Positives = 108/166 (65%)
Frame = +1
Query: 67 IHMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFY 246
++ ++ ID +PAG ++ELY D P+T ENFRALCTGEKG + LH++ + F+
Sbjct: 6 VYFDMTIDGQPAGRIVMELYTDKTPRTAENFRALCTGEKGVGGTGK----PLHFKGSKFH 61
Query: 247 RLVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFI 426
R++PN QGGD G G+GGESIYG FEDE+F KH GILSMAN G +TN SQFFI
Sbjct: 62 RVIPNFMCQGGDFTAGNGTGGESIYGSKFEDENFERKHTGPGILSMANAGANTNGSQFFI 121
Query: 427 TLTPGTWMDTRYVAFGAIIEGSETLKKMEAVPTMNERPVKNIKIKD 564
W+D ++V FG ++EG + +K +E V + + +P K + + D
Sbjct: 122 CTVKTDWLDGKHVVFGQVVEGLDVVKAIEKVGSSSGKPTKPVVVAD 167
>sp|P73789|PPI2_SYNY3 Peptidyl-prolyl cis-trans isomerase slr1251 (PPIase) (Rotamase)
Length = 171
Score = 158 bits (400), Expect = 1e-38
Identities = 76/166 (45%), Positives = 111/166 (66%)
Frame = +1
Query: 67 IHMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFY 246
+ +I I + AG ++EL++++ PKT ENFRALCTGEKG K + LH++ + F+
Sbjct: 5 VFFDITIGSDTAGRIVMELFDEVTPKTAENFRALCTGEKGVGKAGK----PLHFKGSHFH 60
Query: 247 RLVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFI 426
R++ + QGGD G G+GGESIYG F DE+F +KHDR G+LSMAN G +TN SQFF+
Sbjct: 61 RVITDFMAQGGDFTRGNGTGGESIYGEKFADENFQLKHDRPGLLSMANAGPNTNGSQFFL 120
Query: 427 TLTPGTWMDTRYVAFGAIIEGSETLKKMEAVPTMNERPVKNIKIKD 564
T P W+D ++V FG ++EG E L+++EA + + + + I I D
Sbjct: 121 TFVPCPWLDGKHVVFGEVVEGLEILEQLEANGSQSGQTKQAIVISD 166
>sp|P52009|CYP1_CAEEL Peptidyl-prolyl cis-trans isomerase 1 (PPIase) (Rotamase)
(Cyclophilin-1)
Length = 192
Score = 158 bits (399), Expect = 1e-38
Identities = 77/166 (46%), Positives = 105/166 (63%)
Frame = +1
Query: 67 IHMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFY 246
+ ++ I EEPAG +EL+ND+VPKT ENFRALCTGEKG + LH++ + F+
Sbjct: 24 VFFDVSIGEEPAGRVTMELFNDVVPKTAENFRALCTGEKGVGEQGVA----LHFKGSKFH 79
Query: 247 RLVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFI 426
R++P IQGGD G+GGESIYG F+DE+F +KH G LSMAN G +TN SQFFI
Sbjct: 80 RIIPEFMIQGGDFTRHNGTGGESIYGNKFKDENFDLKHTGPGCLSMANAGPNTNGSQFFI 139
Query: 427 TLTPGTWMDTRYVAFGAIIEGSETLKKMEAVPTMNERPVKNIKIKD 564
W+D +V FG + +G +KK+E + + + P K + I D
Sbjct: 140 CTVDTPWLDGGHVVFGQVTDGMSVVKKIEKMGSRSGAPAKTVTIAD 185
>sp|P52010|CYP2_CAEEL Peptidyl-prolyl cis-trans isomerase 2 (PPIase) (Rotamase)
(Cyclophilin-2)
Length = 172
Score = 157 bits (398), Expect = 2e-38
Identities = 78/168 (46%), Positives = 109/168 (64%)
Frame = +1
Query: 61 IYIHMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTI 240
+ + +I I + G ++ELYNDIVPKT ENFRALCTGEKG+ K + KLH++ +
Sbjct: 4 VKVFFDITIGGKKGGRIVMELYNDIVPKTAENFRALCTGEKGKGKSGK----KLHFKGSK 59
Query: 241 FYRLVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQF 420
F+R++P IQGGD G G+GGESI+G F+DE+F KH G+LSMAN G +TN SQF
Sbjct: 60 FHRIIPEFMIQGGDFTEGNGTGGESIHGEKFDDENFKEKHTGPGVLSMANCGANTNGSQF 119
Query: 421 FITLTPGTWMDTRYVAFGAIIEGSETLKKMEAVPTMNERPVKNIKIKD 564
F+ TW+D ++V FG +IEG + +K +E+ + + P I D
Sbjct: 120 FLCTVKTTWLDGKHVVFGKVIEGMDVVKAIESKGSEDGAPSAPCVIAD 167
>sp|P52015|CYP7_CAEEL Peptidyl-prolyl cis-trans isomerase 7 (PPIase) (Rotamase)
(Cyclophilin-7)
Length = 171
Score = 155 bits (393), Expect = 6e-38
Identities = 77/166 (46%), Positives = 104/166 (62%)
Frame = +1
Query: 67 IHMEIEIDEEPAGSFLIELYNDIVPKTCENFRALCTGEKGESKHNEVETFKLHYQNTIFY 246
+ +I I +P G ++ELYNDIVPKT ENFRALCTGEKG K + LH++ + F+
Sbjct: 6 VFFDITIAGKPTGRIVMELYNDIVPKTAENFRALCTGEKGVGKSGK----PLHFKGSKFH 61
Query: 247 RLVPNGWIQGGDIWYGRGSGGESIYGPTFEDESFAIKHDRRGILSMANRGRHTNQSQFFI 426
R++P IQGGD G G+GGESIYG F DE+F KH G+LSMAN G +TN SQFF+
Sbjct: 62 RIIPEFMIQGGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAGPNTNGSQFFL 121
Query: 427 TLTPGTWMDTRYVAFGAIIEGSETLKKMEAVPTMNERPVKNIKIKD 564
W+D ++V FG ++EG + + K+E + + P I D
Sbjct: 122 CTVKTAWLDGKHVVFGRVVEGLDIVSKVEGNGSSSGTPKSECLIAD 167
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,624,348
Number of Sequences: 369166
Number of extensions: 1704583
Number of successful extensions: 4811
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4504
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4654
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5169945420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)