Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02663
(664 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q09406|YRG5_CAEEL Hypothetical WD-repeat protein K06A1.5... 53 8e-07
sp|P32330|YKM1_YEAST Hypothetical WD repeat-containing prot... 47 6e-05
sp|O15736|TIPD_DICDI Protein tipD 46 8e-05
sp|Q93847|YZLL_CAEEL Hypothetical WD-repeat protein K04G11.... 45 2e-04
sp|Q8N157|AHI1_HUMAN Jouberin (Abelson helper integration s... 45 2e-04
sp|Q19124|YDEM_CAEEL Hypothetical WD-repeat protein F02E8.5... 45 2e-04
sp|Q6DTM3|AHI1_RAT Jouberin (Abelson helper integration sit... 44 3e-04
sp|Q8K3E5|AHI1_MOUSE Jouberin (Abelson helper integration s... 43 6e-04
sp|Q24371|L2DTL_DROME Lethal(2)denticleless protein (Protei... 42 0.001
sp|P61964|WDR5_HUMAN WD-repeat protein 5 (BMP2-induced 3-kb... 42 0.001
>sp|Q09406|YRG5_CAEEL Hypothetical WD-repeat protein K06A1.5 in chromosome II
Length = 464
Score = 52.8 bits (125), Expect = 8e-07
Identities = 31/92 (33%), Positives = 53/92 (57%), Gaps = 3/92 (3%)
Frame = +1
Query: 100 RVTAIEVDPTDSCKILVTTNDSRVRLIDARDYHIICKYRG--FINSSSRIRASFSPTGKY 273
+V+++++ D ++L ++ D + LID R+Y II Y + S RA FS TG+Y
Sbjct: 347 KVSSLDIS-MDGLQVLASSRDDTLSLIDVRNYGIIHLYSAEQYKTSCDSTRAIFSSTGEY 405
Query: 274 IISGSENSFFYIWK-KDVEVNKMTRFSTTRKD 366
+++GS NS +IW K ++ K+ + T R D
Sbjct: 406 VLAGSSNSSVFIWNTKTTKLEKVVK--TARSD 435
>sp|P32330|YKM1_YEAST Hypothetical WD repeat-containing protein YKL121w
Length = 852
Score = 46.6 bits (109), Expect = 6e-05
Identities = 48/233 (20%), Positives = 95/233 (40%), Gaps = 22/233 (9%)
Frame = +1
Query: 1 VGTYDGRI-LFYTAELEYITSMAIK----------SSHRKNKYC------RVTAIEV--- 120
+GT++G I + T L++++S + S H ++Y R+T ++
Sbjct: 380 IGTFNGYIYVLLTHGLKFVSSFHVSDKSTQGTTKNSFHPSSEYGKVQHGPRITGLQCFFS 439
Query: 121 DPTDSCKILVTTNDSRVRLIDARDYHIICKYRGFINSSSRIRASF--SPTGKYIISGSEN 294
+ +++VTTNDS++++ D + + ++GF + SSR R F + +GS++
Sbjct: 440 KVDKNLRLIVTTNDSKIQIFDLNEKKPLELFKGFQSGSSRHRGQFLMMKNEPVVFTGSDD 499
Query: 295 SFFYIWKKDVEVNKMTRFSTTRKDRNNYWEAIKAHETVVSVSAFSPTPHLVLDKKFRRRH 474
+FY WK N + T R + + ++ + + T L + +
Sbjct: 500 HWFYTWKMQ-SFNLSAEMNCTAPHRKKRLSGSMSLKGLLRIVSNKSTNDECLTETSNQSS 558
Query: 475 SINMSTHPYSLDQHSYVNKSENYLGEVIVSADISGVIRVFKNRLHSLPVSAKS 633
S H++ N S+N L V + H+ PV+ S
Sbjct: 559 S------------HTFTNSSKNVLQTQTVGSQAIKNNHYISFHAHNSPVTCAS 599
>sp|O15736|TIPD_DICDI Protein tipD
Length = 612
Score = 46.2 bits (108), Expect = 8e-05
Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Frame = +1
Query: 100 RVTAIEVDPTDSCKILVTTNDSRVRLIDARDYHIICKYRG--FINSSSRIRASFSPTGKY 273
++T+I PT++ +IL + D +++ID R + I ++ + N + +AS+SP G+Y
Sbjct: 494 QITSITNSPTNTNQILTNSRDHTLKIIDIRTFDTIRTFKDPEYRNGLNWTKASWSPDGRY 553
Query: 274 IISGSENSFFYIW 312
I SGS + IW
Sbjct: 554 IASGSIDGSICIW 566
>sp|Q93847|YZLL_CAEEL Hypothetical WD-repeat protein K04G11.4 IN chromosome X
Length = 395
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Frame = +1
Query: 4 GTYDGRILFYTAELEYITSMAIKSSHRKNKYCRVTAIEVDPTDSCKILVTTNDSRVRLID 183
G+YDG + + + I H +T ++ P IL + ++ ++L D
Sbjct: 250 GSYDGIVRIWDSTTGTCVKTLIDEEHPP-----ITHVKFSPNGKY-ILASNLNNTLKLWD 303
Query: 184 ARDYHIICKYRGFINSSSRIRASFSPTG-KYIISGSENSFFYIW 312
+ ++ +Y G NS + A+FS TG K+I+SGSE+ YIW
Sbjct: 304 YQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIW 347
>sp|Q8N157|AHI1_HUMAN Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1)
Length = 1196
Score = 44.7 bits (104), Expect = 2e-04
Identities = 20/73 (27%), Positives = 42/73 (57%)
Frame = +1
Query: 103 VTAIEVDPTDSCKILVTTNDSRVRLIDARDYHIICKYRGFINSSSRIRASFSPTGKYIIS 282
++ +E+ P ++L+ T DS +R++D R + K+ G N +I ++ +P G ++ +
Sbjct: 803 ISYLEIHPNGK-RLLIHTKDSTLRIMDLRIL-VARKFVGAANYREKIHSTLTPCGTFLFA 860
Query: 283 GSENSFFYIWKKD 321
GSE+ Y+W +
Sbjct: 861 GSEDGIVYVWNPE 873
>sp|Q19124|YDEM_CAEEL Hypothetical WD-repeat protein F02E8.5 in chromosome X
Length = 578
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Frame = +1
Query: 100 RVTAIEVDPTDSCKILVTTNDSRVRLIDARDYHIICKY--RGFINSSSRIRASFSPTGKY 273
R+T+++V + C++LV+T D + LID R + + Y + SS R S +Y
Sbjct: 463 RITSLDVTMS-GCELLVSTRDDTISLIDLRTFQTVHCYSAENYRTSSDLSRVVLSSGNEY 521
Query: 274 IISGSENSFFYIWKKD 321
+ +GS N ++W ++
Sbjct: 522 VAAGSSNGSIFVWNRN 537
>sp|Q6DTM3|AHI1_RAT Jouberin (Abelson helper integration site 1 protein homolog)
(AHI-1)
Length = 1047
Score = 44.3 bits (103), Expect = 3e-04
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
Frame = +1
Query: 103 VTAIEVDPTDSCKILVTTNDSRVRLIDARDYHIICKYRGFINSSSRIRASFSPTGKYIIS 282
V+ +EV P ++L+ T DS +R++D R K+ G N +I ++ +P G + S
Sbjct: 654 VSYLEVHPNGK-RLLIHTKDSTLRIMDLRIL-AARKFVGAANYREKIHSTLTPCGTLLFS 711
Query: 283 GSENSFFYIWK----KDVEVNKMTRFSTTRKDRNNYWEAIKAHETVVSVSAFSPTPHLVL 450
GSE+ Y+W + V + F +T +D + + E +V+ AF + ++L
Sbjct: 712 GSEDGIVYVWNPETGEQVAMYSELPFKSTIRDISYH-----PFENMVAFCAFGQSEPILL 766
>sp|Q8K3E5|AHI1_MOUSE Jouberin (Abelson helper integration site 1 protein) (AHI-1)
Length = 1047
Score = 43.1 bits (100), Expect = 6e-04
Identities = 22/73 (30%), Positives = 40/73 (54%)
Frame = +1
Query: 103 VTAIEVDPTDSCKILVTTNDSRVRLIDARDYHIICKYRGFINSSSRIRASFSPTGKYIIS 282
++ +EV P ++L+ T DS +R++D R K+ G N +I ++ +P G + S
Sbjct: 653 ISYLEVHPNGK-RLLIHTKDSTLRIMDLRIL-AARKFVGAANYREKIHSTLTPCGTLLFS 710
Query: 283 GSENSFFYIWKKD 321
GSE+ Y+W +
Sbjct: 711 GSEDGIVYVWNPE 723
>sp|Q24371|L2DTL_DROME Lethal(2)denticleless protein (Protein DTL83)
Length = 769
Score = 42.4 bits (98), Expect = 0.001
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 211 YRGFINSSSRIRASFSPTGKYIISGSENSFFYIWKKD 321
Y+G +NS+ I++ SP GKY++SGS + YIW D
Sbjct: 315 YKGLLNSTFYIKSCLSPDGKYLLSGSSDERAYIWNLD 351
>sp|P61964|WDR5_HUMAN WD-repeat protein 5 (BMP2-induced 3-kb gene protein)
sp|P61965|WDR5_MOUSE WD-repeat protein 5 (BMP2-induced 3-kb gene protein) (WD-repeat
protein BIG-3)
Length = 334
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 1/116 (0%)
Frame = +1
Query: 142 ILVTTNDSRVRLIDARDYHIICKYRGFINSSSRIRASFSPTG-KYIISGSENSFFYIWKK 318
IL T D+ ++L D + Y G N I A+FS TG K+I+SGSE++ YIW
Sbjct: 229 ILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIW-- 286
Query: 319 DVEVNKMTRFSTTRKDRNNYWEAIKAHETVVSVSAFSPTPHLVLDKKFRRRHSINM 486
N T+ + ++ H VV +A PT +++ +I +
Sbjct: 287 ----NLQTK---------EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKL 329
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,443,604
Number of Sequences: 369166
Number of extensions: 1294342
Number of successful extensions: 3804
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3555
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3793
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5560129980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)