Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02585
(507 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P70083|AT2A1_MAKNI Sarcoplasmic/endoplasmic reticulum ca... 272 3e-73
sp|P35316|ATC_ARTSF Calcium-transporting ATPase sarcoplasmi... 270 1e-72
sp|P13585|AT2A1_CHICK Sarcoplasmic/endoplasmic reticulum ca... 270 1e-72
sp|O14983|AT2A1_HUMAN Sarcoplasmic/endoplasmic reticulum ca... 270 2e-72
sp|Q64578|AT2A1_RAT Sarcoplasmic/endoplasmic reticulum calc... 269 2e-72
sp|Q8R429|AT2A1_MOUSE Sarcoplasmic/endoplasmic reticulum ca... 269 2e-72
sp|P04191|AT2A1_RABIT Sarcoplasmic/endoplasmic reticulum ca... 268 5e-72
sp|P22700|ATC1_DROME Calcium-transporting ATPase sarcoplasm... 268 5e-72
sp|Q92105|AT2A1_RANES Sarcoplasmic/endoplasmic reticulum ca... 268 7e-72
sp|P20647|AT2A2_RABIT Sarcoplasmic/endoplasmic reticulum ca... 267 1e-71
>sp|P70083|AT2A1_MAKNI Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 996
Score = 272 bits (696), Expect = 3e-73
Identities = 137/167 (82%), Positives = 143/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFS+IVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 703 NDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSSIVAAVEEGRAIYNNMKQFIRYLI 762
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRS K
Sbjct: 763 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSPK 822
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRYM WWF GP + YYQL+H
Sbjct: 823 EPLISGWLFFRYMAIGGYVGAATVGGAAWWFLYDSTGPAVTYYQLSH 869
>sp|P35316|ATC_ARTSF Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type
(Calcium pump)
Length = 1003
Score = 270 bits (690), Expect = 1e-72
Identities = 136/168 (80%), Positives = 143/168 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAKSA+EMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 710 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 769
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSN+GEVVSIFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM KPPR
Sbjct: 770 SSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRRAD 829
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTHH 505
E LITGWLFFRYM WF + P GP LN+YQL+HH
Sbjct: 830 EGLITGWLFFRYMAIGTYVGAATVGAAAHWFMMSPTGPGLNFYQLSHH 877
>sp|P13585|AT2A1_CHICK Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 994
Score = 270 bits (690), Expect = 1e-72
Identities = 136/167 (81%), Positives = 142/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM KPPRS K
Sbjct: 766 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDKPPRSPK 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRY+ WWF GP L Y+QLTH
Sbjct: 826 EPLISGWLFFRYLAIGGYVGAATVGAAAWWFLYAEDGPSLTYHQLTH 872
>sp|O14983|AT2A1_HUMAN Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1001
Score = 270 bits (689), Expect = 2e-72
Identities = 136/167 (81%), Positives = 142/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPRS K
Sbjct: 766 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPK 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRYM WWF GP +NY QLTH
Sbjct: 826 EPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTH 872
>sp|Q64578|AT2A1_RAT Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 994
Score = 269 bits (688), Expect = 2e-72
Identities = 135/167 (80%), Positives = 143/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPRS K
Sbjct: 766 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPK 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRYM WWF GP ++Y+QLTH
Sbjct: 826 EPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVSYHQLTH 872
>sp|Q8R429|AT2A1_MOUSE Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 994
Score = 269 bits (688), Expect = 2e-72
Identities = 135/167 (80%), Positives = 143/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPRS K
Sbjct: 766 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPK 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRYM WWF GP ++Y+QLTH
Sbjct: 826 EPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVSYHQLTH 872
>sp|P04191|AT2A1_RABIT Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1001
Score = 268 bits (685), Expect = 5e-72
Identities = 135/167 (80%), Positives = 142/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPRS K
Sbjct: 766 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPK 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRYM WWF GP + Y+QLTH
Sbjct: 826 EPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTH 872
>sp|P22700|ATC1_DROME Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type
(Calcium pump)
Length = 1020
Score = 268 bits (685), Expect = 5e-72
Identities = 133/168 (79%), Positives = 143/168 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAKSA+EMVLADDNFS+IV+AVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSN+GEVVSIFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM KPPR
Sbjct: 766 SSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRKAD 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTHH 505
E LI+GWLFFRYM WWF GP+L+Y+QLTHH
Sbjct: 826 EGLISGWLFFRYMAIGFYVGAATVGAAAWWFVFSDEGPKLSYWQLTHH 873
>sp|Q92105|AT2A1_RANES Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Calcium pump 1)
(SERCA1) (SR Ca(2+)-ATPase 1) (Calcium-transporting
ATPase sarcoplasmic reticulum type, fast twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 994
Score = 268 bits (684), Expect = 7e-72
Identities = 134/167 (80%), Positives = 142/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 706 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 765
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG+PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM +PPRS K
Sbjct: 766 SSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPK 825
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRYM WWF GP + +YQL+H
Sbjct: 826 EPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYADDGPNVTFYQLSH 872
>sp|P20647|AT2A2_RABIT Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (Calcium pump 2)
(SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting
ATPase sarcoplasmic reticulum type, slow twitch skeletal
muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+)
ATPase)
Length = 1042
Score = 267 bits (682), Expect = 1e-71
Identities = 133/167 (79%), Positives = 143/167 (85%)
Frame = +2
Query: 2 HDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 181
+DAPALKKAEIGIAMGSGTAVAK+ASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI
Sbjct: 705 NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLI 764
Query: 182 SSNVGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMGKPPRSTK 361
SSNVGEVV IFLTAALG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM KPPR+ K
Sbjct: 765 SSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPK 824
Query: 362 EPLITGWLFFRYMXXXXXXXXXXXXXXXWWFTIYPRGPQLNYYQLTH 502
EPLI+GWLFFRY+ WWF GP++++YQL+H
Sbjct: 825 EPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSH 871
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,218,245
Number of Sequences: 369166
Number of extensions: 1011742
Number of successful extensions: 3318
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3147
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3220
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3206272875
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)