Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02581
(778 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delt... 192 9e-49
sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-... 192 9e-49
sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-de... 192 9e-49
sp|Q9JMK2|KC1E_MOUSE Casein kinase I, epsilon isoform (CKI-... 192 9e-49
sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-al... 190 4e-48
sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-al... 190 4e-48
sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-al... 190 4e-48
sp|P42158|KC1D_ARATH Casein kinase I, delta isoform-like (C... 189 6e-48
sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alph... 189 9e-48
sp|P40235|HHP1_SCHPO Casein kinase I homolog hhp1 187 3e-47
>sp|Q06486|KC1D_RAT Casein kinase I, delta isoform (CKI-delta)
sp|Q9DC28|KC1D_MOUSE Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 192 bits (488), Expect = 9e-49
Identities = 96/155 (61%), Positives = 115/155 (74%)
Frame = +1
Query: 19 LANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQGGTG 198
+ N +RL +K+GSGSFG IYL I+ E AIKLE VK+++PQL E +YK +QGG G
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 199 IPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIEYLHS 378
IP I W G +G +Y +VME LGPSLEDLF FC R FSL TVLLLA QMISRIEY+HS
Sbjct: 65 IPTIRWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 379 KHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
K+ IHRD+KPDNF+MG G N VYI+DFGL+K Y
Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
Score = 82.0 bits (201), Expect = 2e-15
Identities = 39/64 (60%), Positives = 44/64 (68%)
Frame = +2
Query: 536 RDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESIAYCLIYFLKRQLPWQGL 715
RD T+ HI R K LTG+ RYASINTH G EQSRRDD+ES+ Y L+YF LPWQGL
Sbjct: 157 RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGL 216
Query: 716 DGGT 727
T
Sbjct: 217 KAAT 220
>sp|P49674|KC1E_HUMAN Casein kinase I, epsilon isoform (CKI-epsilon) (CKIe)
Length = 416
Score = 192 bits (488), Expect = 9e-49
Identities = 96/155 (61%), Positives = 115/155 (74%)
Frame = +1
Query: 19 LANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQGGTG 198
+ N +RL +K+GSGSFG IYL +I+ E AIKLE VK+++PQL E YK +QGG G
Sbjct: 5 VGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVG 64
Query: 199 IPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIEYLHS 378
IP I W G +G +Y +VME LGPSLEDLF FC R FSL TVLLLA QMISRIEY+HS
Sbjct: 65 IPSIKWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 379 KHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
K+ IHRD+KPDNF+MG G N VYI+DFGL+K Y
Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
Score = 82.0 bits (201), Expect = 2e-15
Identities = 39/64 (60%), Positives = 44/64 (68%)
Frame = +2
Query: 536 RDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESIAYCLIYFLKRQLPWQGL 715
RD T+ HI R K LTG+ RYASINTH G EQSRRDD+ES+ Y L+YF LPWQGL
Sbjct: 157 RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGL 216
Query: 716 DGGT 727
T
Sbjct: 217 KAAT 220
>sp|P48730|KC1D_HUMAN Casein kinase I, delta isoform (CKI-delta) (CKId)
Length = 415
Score = 192 bits (488), Expect = 9e-49
Identities = 96/155 (61%), Positives = 115/155 (74%)
Frame = +1
Query: 19 LANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQGGTG 198
+ N +RL +K+GSGSFG IYL I+ E AIKLE VK+++PQL E +YK +QGG G
Sbjct: 5 VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
Query: 199 IPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIEYLHS 378
IP I W G +G +Y +VME LGPSLEDLF FC R FSL TVLLLA QMISRIEY+HS
Sbjct: 65 IPTIRWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 379 KHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
K+ IHRD+KPDNF+MG G N VYI+DFGL+K Y
Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
Score = 82.0 bits (201), Expect = 2e-15
Identities = 39/64 (60%), Positives = 44/64 (68%)
Frame = +2
Query: 536 RDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESIAYCLIYFLKRQLPWQGL 715
RD T+ HI R K LTG+ RYASINTH G EQSRRDD+ES+ Y L+YF LPWQGL
Sbjct: 157 RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGL 216
Query: 716 DGGT 727
T
Sbjct: 217 KAAT 220
>sp|Q9JMK2|KC1E_MOUSE Casein kinase I, epsilon isoform (CKI-epsilon) (CKIe)
Length = 416
Score = 192 bits (488), Expect = 9e-49
Identities = 96/155 (61%), Positives = 115/155 (74%)
Frame = +1
Query: 19 LANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQGGTG 198
+ N +RL +K+GSGSFG IYL +I+ E AIKLE VK+++PQL E YK +QGG G
Sbjct: 5 VGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVG 64
Query: 199 IPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIEYLHS 378
IP I W G +G +Y +VME LGPSLEDLF FC R FSL TVLLLA QMISRIEY+HS
Sbjct: 65 IPSIKWCGAEG---DYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
Query: 379 KHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
K+ IHRD+KPDNF+MG G N VYI+DFGL+K Y
Sbjct: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY 156
Score = 82.0 bits (201), Expect = 2e-15
Identities = 39/64 (60%), Positives = 44/64 (68%)
Frame = +2
Query: 536 RDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESIAYCLIYFLKRQLPWQGL 715
RD T+ HI R K LTG+ RYASINTH G EQSRRDD+ES+ Y L+YF LPWQGL
Sbjct: 157 RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGL 216
Query: 716 DGGT 727
T
Sbjct: 217 KAAT 220
>sp|P67962|KC1A_CHICK Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67963|KC1A_XENLA Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 190 bits (482), Expect = 4e-48
Identities = 89/159 (55%), Positives = 122/159 (76%)
Frame = +1
Query: 7 SDFILANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQ 186
++FI+ ++L++K+GSGSFG IYLA +I++ E A+KLE K+ +PQL +E +YK LQ
Sbjct: 9 AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
Query: 187 GGTGIPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIE 366
GG GIP I W+G + +Y LVM+ LGPSLEDLF FC R F++ TVL+LA QMISRIE
Sbjct: 69 GGVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125
Query: 367 YLHSKHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
Y+H+K+ IHRDIKPDNF+MG G N+++++DFGL+K Y
Sbjct: 126 YVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
Score = 86.7 bits (213), Expect = 7e-17
Identities = 44/81 (54%), Positives = 49/81 (60%)
Frame = +2
Query: 485 CEKVFHSQFNLISSTISRDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESI 664
C K+F F L RD T HI R K LTG+ RYASIN H G EQSRRDDMES+
Sbjct: 150 CNKLFLIDFGLAKKY--RDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 665 AYCLIYFLKRQLPWQGLDGGT 727
Y L+YF + LPWQGL T
Sbjct: 208 GYVLMYFNRTSLPWQGLKAAT 228
>sp|P48729|KC1A_HUMAN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|Q8BK63|KC1A_MOUSE Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 337
Score = 190 bits (482), Expect = 4e-48
Identities = 89/159 (55%), Positives = 122/159 (76%)
Frame = +1
Query: 7 SDFILANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQ 186
++FI+ ++L++K+GSGSFG IYLA +I++ E A+KLE K+ +PQL +E +YK LQ
Sbjct: 9 AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
Query: 187 GGTGIPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIE 366
GG GIP I W+G + +Y LVM+ LGPSLEDLF FC R F++ TVL+LA QMISRIE
Sbjct: 69 GGVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125
Query: 367 YLHSKHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
Y+H+K+ IHRDIKPDNF+MG G N+++++DFGL+K Y
Sbjct: 126 YVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
Score = 86.7 bits (213), Expect = 7e-17
Identities = 44/81 (54%), Positives = 49/81 (60%)
Frame = +2
Query: 485 CEKVFHSQFNLISSTISRDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESI 664
C K+F F L RD T HI R K LTG+ RYASIN H G EQSRRDDMES+
Sbjct: 150 CNKLFLIDFGLAKKY--RDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 665 AYCLIYFLKRQLPWQGLDGGT 727
Y L+YF + LPWQGL T
Sbjct: 208 GYVLMYFNRTSLPWQGLKAAT 228
>sp|P67829|KC1A_SHEEP Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67828|KC1A_RABIT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
sp|P67827|KC1A_BOVIN Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 190 bits (482), Expect = 4e-48
Identities = 89/159 (55%), Positives = 122/159 (76%)
Frame = +1
Query: 7 SDFILANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQ 186
++FI+ ++L++K+GSGSFG IYLA +I++ E A+KLE K+ +PQL +E +YK LQ
Sbjct: 9 AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
Query: 187 GGTGIPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIE 366
GG GIP I W+G + +Y LVM+ LGPSLEDLF FC R F++ TVL+LA QMISRIE
Sbjct: 69 GGVGIPHIRWYGQE---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125
Query: 367 YLHSKHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
Y+H+K+ IHRDIKPDNF+MG G N+++++DFGL+K Y
Sbjct: 126 YVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
Score = 86.7 bits (213), Expect = 7e-17
Identities = 44/81 (54%), Positives = 49/81 (60%)
Frame = +2
Query: 485 CEKVFHSQFNLISSTISRDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESI 664
C K+F F L RD T HI R K LTG+ RYASIN H G EQSRRDDMES+
Sbjct: 150 CNKLFLIDFGLAKKY--RDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 665 AYCLIYFLKRQLPWQGLDGGT 727
Y L+YF + LPWQGL T
Sbjct: 208 GYVLMYFNRTSLPWQGLKAAT 228
>sp|P42158|KC1D_ARATH Casein kinase I, delta isoform-like (CKI-delta)
Length = 450
Score = 189 bits (481), Expect = 6e-48
Identities = 89/155 (57%), Positives = 118/155 (76%)
Frame = +1
Query: 19 LANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQGGTG 198
+ N +RL +K+GSGSFG IYL +I E AIKLE+VK+++PQL +E +Y+ LQGGTG
Sbjct: 5 VGNKFRLGRKIGSGSFGEIYLGTNIHTNEELAIKLENVKTKHPQLLYESKLYRILQGGTG 64
Query: 199 IPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIEYLHS 378
+P + WFG +G +Y LVM+ LGPSLEDLF FC R SL +VL+LA QMI+R+E+ HS
Sbjct: 65 VPNVKWFGVEG---DYNVLVMDLLGPSLEDLFNFCSRKLSLKSVLMLADQMINRVEFFHS 121
Query: 379 KHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
K +HRD+KPDNF+MG G +N+VYI+DFGL+K Y
Sbjct: 122 KSFLHRDLKPDNFLMGLGRRANQVYIIDFGLAKKY 156
Score = 89.7 bits (221), Expect = 8e-18
Identities = 43/81 (53%), Positives = 52/81 (64%)
Frame = +2
Query: 536 RDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESIAYCLIYFLKRQLPWQGL 715
RD T+ HI R K LTG+ RYAS+NTH G EQSRRDD+ES+ Y L+YFLK LPWQGL
Sbjct: 157 RDSTTHQHIPYRENKNLTGTARYASMNTHLGIEQSRRDDLESLGYILMYFLKGSLPWQGL 216
Query: 716 DGGTXXXXXXXXXXXXINTSL 778
GT ++TS+
Sbjct: 217 KAGTKKQKYERISEKKVSTSI 237
>sp|P97633|KC1A_RAT Casein kinase I, alpha isoform (CKI-alpha) (CK1)
Length = 325
Score = 189 bits (479), Expect = 9e-48
Identities = 89/159 (55%), Positives = 121/159 (76%)
Frame = +1
Query: 7 SDFILANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQ 186
++FI+ ++L++K+GSGSFG IYLA +I++ E A+KLE K+ +PQL +E +YK LQ
Sbjct: 9 AEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ 68
Query: 187 GGTGIPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIE 366
GG GIP I W+G +Y LVM+ LGPSLEDLF FC R F++ TVL+LA QMISRIE
Sbjct: 69 GGVGIPHIRWYGQG---KDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIE 125
Query: 367 YLHSKHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
Y+H+K+ IHRDIKPDNF+MG G N+++++DFGL+K Y
Sbjct: 126 YVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY 164
Score = 86.7 bits (213), Expect = 7e-17
Identities = 44/81 (54%), Positives = 49/81 (60%)
Frame = +2
Query: 485 CEKVFHSQFNLISSTISRDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESI 664
C K+F F L RD T HI R K LTG+ RYASIN H G EQSRRDDMES+
Sbjct: 150 CNKLFLIDFGLAKKY--RDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESL 207
Query: 665 AYCLIYFLKRQLPWQGLDGGT 727
Y L+YF + LPWQGL T
Sbjct: 208 GYVLMYFNRTSLPWQGLKAAT 228
>sp|P40235|HHP1_SCHPO Casein kinase I homolog hhp1
Length = 365
Score = 187 bits (475), Expect = 3e-47
Identities = 90/158 (56%), Positives = 116/158 (73%)
Frame = +1
Query: 10 DFILANHWRLLKKLGSGSFGHIYLAESISDRHEYAIKLEDVKSEYPQLEHERNMYKALQG 189
D + N +R+ +K+GSGSFG IYL ++ E AIKLE ++++PQLE+E +Y+ L G
Sbjct: 4 DLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSG 63
Query: 190 GTGIPIIYWFGYDGVRNEYKALVMEYLGPSLEDLFAFCKRTFSLTTVLLLAQQMISRIEY 369
G GIP + WFG V +Y A+VM+ LGPSLEDLF FC R FSL TVLLLA Q+ISRIE+
Sbjct: 64 GVGIPFVRWFG---VECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEF 120
Query: 370 LHSKHIIHRDIKPDNFVMGHGNLSNRVYIVDFGLSKSY 483
+HSK +HRDIKPDNF+MG G N+V I+DFGL+K Y
Sbjct: 121 IHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKY 158
Score = 84.7 bits (208), Expect = 3e-16
Identities = 42/78 (53%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
Frame = +2
Query: 503 SQFNLISSTIS---RDRNTNSHIHNRTKKGLTGSPRYASINTHNGFEQSRRDDMESIAYC 673
+Q N+I ++ RD T+ HI R K LTG+ RYASINTH G EQSRRDD+ES+ Y
Sbjct: 145 NQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYV 204
Query: 674 LIYFLKRQLPWQGLDGGT 727
L+YF + LPWQGL T
Sbjct: 205 LVYFCRGSLPWQGLKATT 222
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,444,065
Number of Sequences: 369166
Number of extensions: 1560618
Number of successful extensions: 7015
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5846
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6262
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)