Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02575
(748 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O14893|GEMI2_HUMAN Survival of motor neuron protein-inte... 77 6e-14
sp|Q9QZP1|GEMI2_RAT Survival of motor neuron protein-intera... 73 9e-13
sp|Q9CQQ4|GEMI2_MOUSE Survival of motor neuron protein-inte... 73 9e-13
sp|O42260|GEMI2_XENLA Survival of motor neuron protein-inte... 70 5e-12
sp|Q9VUV9|U520_DROME Putative U5 small nuclear ribonucleopr... 32 1.4
sp|O42649|SMC3_SCHPO Structural maintenance of chromosome 3... 32 2.4
sp|Q6P4P1|SPA3A_MOUSE Serine protease inhibitor A3A precurs... 32 2.4
sp|P45354|HXUA2_HAEIN Heme/hemopexin-binding protein precur... 31 4.0
sp|P47386|Y140_MYCGE Hypothetical ATP-binding protein MG140 31 4.0
sp|P57351|PUR8_BUCAI Adenylosuccinate lyase (Adenylosuccina... 30 5.3
>sp|O14893|GEMI2_HUMAN Survival of motor neuron protein-interacting protein 1
(SMN-interacting protein 1) (Component of gems 2)
(Gemin-2)
Length = 280
Score = 76.6 bits (187), Expect = 6e-14
Identities = 65/233 (27%), Positives = 108/233 (46%), Gaps = 20/233 (8%)
Frame = +1
Query: 100 DYLLSVRYENKNLPDIVIKEVKNVTPKNFGLTHSM-ASLIIHKDEVDNQKNALFFEKNNS 276
+YL V+ E PD+V+ ++ PK S+ SL + + L +++
Sbjct: 51 EYLRRVQIEAAQCPDVVVAQID---PKKLKRKQSVNISLSGCQPAPEGYSPTLQWQQQQ- 106
Query: 277 LINEFQELRAAIGKI----KSEKLTNVYKYPDISDEKFWLSFCLGQ-FYADGIEDGSQCE 441
+ +F +R + K KS++L + P DE+ W FCLG+ ADG + E
Sbjct: 107 -VAQFSTVRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWKKFCLGEKLCADGAVGPATNE 165
Query: 442 ------------PIVSVICELSQNQVIKLFGYLAT--GNIPFTHIMGRWIYALLAVIFFP 579
P++S++ ++Q V + YL+ G FT +GRW+YALLA + P
Sbjct: 166 SPGIDYVQIGFPPLLSIVSRMNQATVTSVLEYLSNWFGERDFTPELGRWLYALLACLEKP 225
Query: 580 LDNDAVFSLRSIARNMMHLIKNYDGSDPSLVNSMNSIIVIVTCVFKQMDLINE 738
L +A +R +AR + D D V ++N +I +V+ F Q DL +E
Sbjct: 226 LLPEAHSLIRQLARRCSEVRLLVDSKDDERVPALNLLICLVSRYFDQRDLADE 278
>sp|Q9QZP1|GEMI2_RAT Survival of motor neuron protein-interacting protein 1
(SMN-interacting protein 1) (Component of gems 2)
(Gemin-2)
Length = 269
Score = 72.8 bits (177), Expect = 9e-13
Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 20/233 (8%)
Frame = +1
Query: 100 DYLLSVRYENKNLPDIVIKEVKNVTPKNFGLTHSM-ASLIIHKDEVDNQKNALFFEKNNS 276
+YL V+ E PD+V+ ++ PK S+ SL + L +++
Sbjct: 40 EYLRRVQIEAAQCPDVVVAQID---PKKLKRKQSVNVSLSGCHPAPEGYSPTLQWQQQQV 96
Query: 277 LINEFQELRAAIGKI----KSEKLTNVYKYPDISDEKFWLSFCLGQ-FYADGIEDGSQCE 441
+ +F +R ++ K KS++L + P DE+ W FCLG+ A+G S E
Sbjct: 97 I--QFSSVRQSVHKHRNHWKSQQLDSNVTMPKSEDEEGWKKFCLGERLCAEGATGPSTDE 154
Query: 442 ------------PIVSVICELSQNQVIKLFGYLAT--GNIPFTHIMGRWIYALLAVIFFP 579
P++S++ ++Q + + YL+ G FT +GRW YALLA + P
Sbjct: 155 SPGIDYVQVGFPPLLSIVSRMNQATITSVLEYLSNWFGERDFTPELGRWFYALLACLEKP 214
Query: 580 LDNDAVFSLRSIARNMMHLIKNYDGSDPSLVNSMNSIIVIVTCVFKQMDLINE 738
L +A +R +AR + D V ++N +I +V+ F Q DL +E
Sbjct: 215 LLPEAHSLIRQLARRCSEVRLLVGSKDDERVPALNLLICLVSRYFDQRDLADE 267
>sp|Q9CQQ4|GEMI2_MOUSE Survival of motor neuron protein-interacting protein 1
(SMN-interacting protein 1) (Component of gems 2)
(Gemin-2)
Length = 269
Score = 72.8 bits (177), Expect = 9e-13
Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 20/233 (8%)
Frame = +1
Query: 100 DYLLSVRYENKNLPDIVIKEVKNVTPKNFGLTHSM-ASLIIHKDEVDNQKNALFFEKNNS 276
+YL V+ E PD+V+ ++ PK S+ SL + + L +++
Sbjct: 40 EYLRRVQIEAAQCPDVVVAQID---PKKLKRKQSVNISLSGCQPAPEGYSPTLQWQQQQ- 95
Query: 277 LINEFQELRAAIGKI----KSEKLTNVYKYPDISDEKFWLSFCLGQ-FYADGIEDGSQCE 441
+ F +R ++ K KS++L + P DE+ W FCLG+ A+G S E
Sbjct: 96 -VAHFSTVRQSVHKHRNHWKSQQLDSNVAMPKSEDEEGWKKFCLGERLCAEGATGPSTEE 154
Query: 442 ------------PIVSVICELSQNQVIKLFGYLAT--GNIPFTHIMGRWIYALLAVIFFP 579
P++S++ ++Q + + YL+ G FT +GRW YALLA + P
Sbjct: 155 SPGIDYVQVGFPPLLSIVSRMNQTTITSVLEYLSNWFGERDFTPELGRWFYALLACLEKP 214
Query: 580 LDNDAVFSLRSIARNMMHLIKNYDGSDPSLVNSMNSIIVIVTCVFKQMDLINE 738
L +A +R +AR + D V ++N +I +V+ F Q DL +E
Sbjct: 215 LLPEAHSLIRQLARRCSEVRLLVGSKDDERVPALNLLICLVSRYFDQRDLADE 267
>sp|O42260|GEMI2_XENLA Survival of motor neuron protein-interacting protein 1
(SMN-interacting protein 1) (Component of gems 2)
(Gemin-2)
Length = 259
Score = 70.5 bits (171), Expect = 5e-12
Identities = 62/231 (26%), Positives = 106/231 (45%), Gaps = 21/231 (9%)
Frame = +1
Query: 100 DYLLSVRYENKNLPDIVIKEVKNVTPKNFGLTHSMA-SLIIHKDEVDNQKNALFFEKNNS 276
+YL V+ E PD+VI ++ PK +++ SL + D +L +++
Sbjct: 27 EYLRRVQIEAARCPDVVIAQID---PKKLRKKQTVSISLSGCQPAPDGYSPSLRWQQQQ- 82
Query: 277 LINEFQELRAAI----GKIKSEKLTNVYKYPDISDEKFWLSFCLGQ-FYAD---GIEDGS 432
+ +F +R ++ G +S+ L + P DE+ W FCLG+ Y+D + S
Sbjct: 83 -VAQFSAVRQSLHKHRGHWRSQPLDSNVTMPSTEDEESWKKFCLGERLYSDLAAALNSES 141
Query: 433 Q----------CEPIVSVICELSQNQVIKLFGYLATG--NIPFTHIMGRWIYALLAVIFF 576
Q P++S++ +SQ V + YL FT +GRW+YALLA +
Sbjct: 142 QHPGIDYIKVGFPPLLSIVSRMSQATVTSVLEYLVNWFEERNFTPELGRWLYALLACLEK 201
Query: 577 PLDNDAVFSLRSIARNMMHLIKNYDGSDPSLVNSMNSIIVIVTCVFKQMDL 729
PL +A +R +AR + + + V+ +N I +V F+Q DL
Sbjct: 202 PLLPEAHSLIRQLARRCSQIRAGVEHKEDDRVSPLNLFICLVGRYFEQRDL 252
>sp|Q9VUV9|U520_DROME Putative U5 small nuclear ribonucleoprotein 200 kDa helicase
Length = 2142
Score = 32.3 bits (72), Expect = 1.4
Identities = 13/49 (26%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Frame = +1
Query: 370 EKFWLSFCLGQFYADGIEDGSQCEPIVSVICELS-----QNQVIKLFGY 501
+ +WL CL +FY D + S+ ++ ++ + + +NQ++ L GY
Sbjct: 269 DAYWLQRCLSKFYKDAMVSQSKAADVLKILKDAADDRDCENQLVLLLGY 317
>sp|O42649|SMC3_SCHPO Structural maintenance of chromosome 3 (Cohesin complex Psm3 subunit)
Length = 1194
Score = 31.6 bits (70), Expect = 2.4
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Frame = +1
Query: 94 ANDYLLSVRYENKNLPDIVIKEVKNVTPKNFGLTHSMASLIIHKDEVDNQKNALFFEKNN 273
AND + E L ++ +K+++ + L+H ++I + ++ +K AL +E N
Sbjct: 764 ANDLKSELSSEMDELDPKDVEALKSLSGQIENLSHEFDAIIKERAHIEARKTALEYELNT 823
Query: 274 SLINEFQELRAAIG---KIKSEKLTNV 345
+L L+A IG +I +L +V
Sbjct: 824 NLYLRRNPLKAEIGSDNRIDESELNSV 850
>sp|Q6P4P1|SPA3A_MOUSE Serine protease inhibitor A3A precursor (Serpin A3A)
Length = 422
Score = 31.6 bits (70), Expect = 2.4
Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Frame = +1
Query: 133 NLPDIVIKEVKNVTPKNFGLTHSMASLIIHKDEVD-NQKNALFFEKNNSLINEFQELRAA 309
NLP+ ++ +NFG H + LI +++V N NALF +K+ ++ EF+E A
Sbjct: 106 NLPETPEADIH----QNFG--HLLQMLIQPENQVQINAGNALFIDKHLQILTEFKEKARA 159
Query: 310 IGKIKSEKLTNVYKYP 357
+ K+E T ++ P
Sbjct: 160 L--YKAEAFTTDFQRP 173
>sp|P45354|HXUA2_HAEIN Heme/hemopexin-binding protein precursor (Heme:hemopexin
utilization protein A)
Length = 928
Score = 30.8 bits (68), Expect = 4.0
Identities = 16/53 (30%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 121 YENKNLPDIVIKEVK-NVTPKNFGLTHSMASLIIHKDEVDNQKNALFFEKNNS 276
+ KN IK+ + N++ N L + L+ K ++DN K + F+K+NS
Sbjct: 609 FATKNTGRSTIKDTEINISNSNINLKNGFVHLLAEKIKLDNSKIDITFDKDNS 661
>sp|P47386|Y140_MYCGE Hypothetical ATP-binding protein MG140
Length = 1113
Score = 30.8 bits (68), Expect = 4.0
Identities = 26/115 (22%), Positives = 57/115 (49%), Gaps = 2/115 (1%)
Frame = +1
Query: 61 DKFKKDSQFSSANDYLLSVRYENKNLPDI--VIKEVKNVTPKNFGLTHSMASLIIHKDEV 234
+K D + +D + + N+NL + V++ ++ +T N S+ + +K++
Sbjct: 805 NKANADQRVFIVHDVIDGIWKNNRNLQEARDVVQRLEQLTTTN-DYKKSLGVICFNKNQA 863
Query: 235 DNQKNALFFEKNNSLINEFQELRAAIGKIKSEKLTNVYKYPDISDEKFWLSFCLG 399
D + L ++NN L+NE++E + +G+ + + N+ DE+ + F LG
Sbjct: 864 DLIEY-LIDKQNNPLLNEWRERQNDVGEYEGLFVKNIENVQ--GDERDIIIFSLG 915
>sp|P57351|PUR8_BUCAI Adenylosuccinate lyase (Adenylosuccinase) (ASL)
Length = 456
Score = 30.4 bits (67), Expect = 5.3
Identities = 14/54 (25%), Positives = 29/54 (53%)
Frame = +1
Query: 25 TAAKFFYVEGEYDKFKKDSQFSSANDYLLSVRYENKNLPDIVIKEVKNVTPKNF 186
T + + ++ Y+K KK ++ N ++ + N+P+ K +KN+TP N+
Sbjct: 391 TIMRRYGIKNAYEKLKKLTRGKEINRNVIHTFISSLNIPEEEKKRLKNMTPFNY 444
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,868,269
Number of Sequences: 369166
Number of extensions: 1434609
Number of successful extensions: 3678
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3669
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)