Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02574
(398 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinas... 72 5e-13
sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 71 9e-13
sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 (S... 70 2e-12
sp|Q01389|BCK1_YEAST Serine/threonine-protein kinase BCK1/S... 68 7e-12
sp|Q12469|SKM1_YEAST Serine/threonine-protein kinase SKM1 (... 67 1e-11
sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 ... 66 2e-11
sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 (S... 66 2e-11
sp|Q9P289|MST4_HUMAN Serine/threonine-protein kinase MST4 (... 66 2e-11
sp|Q99JT2|MST4_MOUSE Serine/threonine-protein kinase MST4 (... 66 2e-11
sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 (S... 66 2e-11
>sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kinase 2 (Arabidospsis
NPK1-related protein kinase 2)
Length = 651
Score = 71.6 bits (174), Expect = 5e-13
Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 2/91 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
Y+MAPE+I +S DIWS G ++EMVTGK P W + ++ + I + + P +
Sbjct: 238 YWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAP--WSQQYKEIAAIFHIGTTKSHPPI 295
Query: 208 P--ISNELNQFISSCLNMNPNERPSAQQLIK 294
P IS++ N F+ CL PN RP+A +L+K
Sbjct: 296 PDNISSDANDFLLKCLQQEPNLRPTASELLK 326
>sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24
Length = 431
Score = 70.9 bits (172), Expect = 9e-13
Identities = 36/96 (37%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
++MAPE+IK +Y +K DIWS G+ +E+ G+ P L P + + I PTL
Sbjct: 184 FWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPK----NNPPTL 239
Query: 208 P--ISNELNQFISSCLNMNPNERPSAQQLIKSKLFI 309
S L +F+ +CLN P+ RP+A++L+K K I
Sbjct: 240 EGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFII 275
>sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 (STE20-like kinase MST3) (MST-3)
(Mammalian STE20-like protein kinase 3)
Length = 443
Score = 70.1 bits (170), Expect = 2e-12
Identities = 35/96 (36%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
++MAPE+IK +Y +K DIWS G+ +E+ G+ P L P + + I PTL
Sbjct: 196 FWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPK----NNPPTL 251
Query: 208 P--ISNELNQFISSCLNMNPNERPSAQQLIKSKLFI 309
S L +F+ +CLN P+ RP+A++L+K K +
Sbjct: 252 EGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIL 287
>sp|Q01389|BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SSP31
Length = 1478
Score = 67.8 bits (164), Expect = 7e-12
Identities = 33/93 (35%), Positives = 60/93 (64%), Gaps = 4/93 (4%)
Frame = +1
Query: 25 IYYMAPELIKS-ESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDP 201
+++MAPE++ + + YS K+DIWS G +++EM GKRP+ L+ A+ +I P
Sbjct: 1343 VFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIP 1402
Query: 202 --TLPISNELNQ-FISSCLNMNPNERPSAQQLI 291
TLP+ +++ + F+ +C +NP +RP+A +L+
Sbjct: 1403 EDTLPLISQIGRNFLDACFEINPEKRPTANELL 1435
>sp|Q12469|SKM1_YEAST Serine/threonine-protein kinase SKM1 (Protein kinase 75490 D)
Length = 655
Score = 67.0 bits (162), Expect = 1e-11
Identities = 28/88 (31%), Positives = 52/88 (59%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
Y+MAPE++ + Y K+D+WS G++++EM+ G+ P+ P +A+ I N +
Sbjct: 547 YWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRHPE 606
Query: 208 PISNELNQFISSCLNMNPNERPSAQQLI 291
+S + QF+ +CL +N R S ++L+
Sbjct: 607 SVSKQTKQFLDACLQVNVESRASVRKLL 634
>sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 (p21-activated kinase 6)
(PAK-6) (PAK-5)
Length = 681
Score = 66.2 bits (160), Expect = 2e-11
Identities = 31/88 (35%), Positives = 54/88 (61%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
Y+MAPE+I Y+ ++DIWS G++++EMV G+ P+ P QA+ ++R+ + +
Sbjct: 566 YWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSH 625
Query: 208 PISNELNQFISSCLNMNPNERPSAQQLI 291
+S L F+ L +P ER +AQ+L+
Sbjct: 626 KVSPVLRDFLERMLVRDPQERATAQELL 653
>sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 (Sterile 20/oxidant
stress-response kinase 1) (Ste20/oxidant stress response
kinase-1) (SOK-1) (Ste20-like kinase)
Length = 426
Score = 66.2 bits (160), Expect = 2e-11
Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
++MAPE+IK +Y K DIWS G+ +E+ G+ P L P + + I PTL
Sbjct: 180 FWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPK----NSPPTL 235
Query: 208 --PISNELNQFISSCLNMNPNERPSAQQLIKSKLFIDYS 318
S +F+ +CLN +P RP+A++L+K K Y+
Sbjct: 236 EGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYT 274
>sp|Q9P289|MST4_HUMAN Serine/threonine-protein kinase MST4 (STE20-like kinase MST4)
(MST-4) (Mammalian STE20-like protein kinase 4)
(Serine/threonine-protein kinase MASK) (Mst3 and
SOK1-related kinase)
Length = 416
Score = 66.2 bits (160), Expect = 2e-11
Identities = 33/99 (33%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
++MAPE+I+ +Y +K DIWS G+ +E+ G+ P + P + + I PTL
Sbjct: 184 FWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPK----NNPPTL 239
Query: 208 --PISNELNQFISSCLNMNPNERPSAQQLIKSKLFIDYS 318
+ +FI +CLN +P+ RP+A++L+K K + S
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNS 278
>sp|Q99JT2|MST4_MOUSE Serine/threonine-protein kinase MST4 (STE20-like kinase MST4)
(MST-4) (Mammalian STE20-like protein kinase 4)
Length = 416
Score = 66.2 bits (160), Expect = 2e-11
Identities = 33/99 (33%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
++MAPE+I+ +Y +K DIWS G+ +E+ G+ P + P + + I PTL
Sbjct: 184 FWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPK----NNPPTL 239
Query: 208 --PISNELNQFISSCLNMNPNERPSAQQLIKSKLFIDYS 318
+ +FI +CLN +P+ RP+A++L+K K + S
Sbjct: 240 IGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNS 278
>sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 (Sterile 20/oxidant
stress-response kinase 1) (Ste20/oxidant stress response
kinase-1) (SOK-1) (Ste20-like kinase)
Length = 426
Score = 66.2 bits (160), Expect = 2e-11
Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Frame = +1
Query: 28 YYMAPELIKSESYSNKIDIWSFGMVMVEMVTGKRPFHWLKPFQAVLQIRNCTKYEYDPTL 207
++MAPE+IK +Y K DIWS G+ +E+ G+ P L P + + I PTL
Sbjct: 180 FWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPK----NNPPTL 235
Query: 208 P--ISNELNQFISSCLNMNPNERPSAQQLIKSKLFIDYS 318
S +F+ +CLN +P RP+A++L+K K Y+
Sbjct: 236 EGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYT 274
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,164,285
Number of Sequences: 369166
Number of extensions: 891649
Number of successful extensions: 3542
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3201
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3301
length of database: 68,354,980
effective HSP length: 98
effective length of database: 50,250,950
effective search space used: 1708532300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)