Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02543
(522 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q12996|CSTF3_HUMAN Cleavage stimulation factor, 77 kDa s... 74 2e-13
sp|Q5RDW9|CSTF3_PONPY Cleavage stimulation factor, 77 kDa s... 74 2e-13
sp|Q99LI7|CSTF3_MOUSE Cleavage stimulation factor, 77 kDa s... 74 2e-13
sp|P25991|SUF_DROME Suppressor of forked protein 65 1e-10
sp|O13911|PNK1_SCHPO Bifunctional polynucleotide phosphatas... 31 2.0
sp|Q8INR6|DOT1L_DROME Histone-lysine N-methyltransferase, H... 30 2.7
sp|Q8SX83|SPEN_DROME Split ends protein 30 4.6
sp|P0A2T6|CRP_SALTY Catabolite gene activator (cAMP recepto... 29 6.0
sp|Q28689|MRP2_RABIT Canalicular multispecific organic anio... 29 6.0
sp|P38836|ECM14_YEAST Extracellular matrix protein 14 precu... 29 7.8
>sp|Q12996|CSTF3_HUMAN Cleavage stimulation factor, 77 kDa subunit (CSTF 77 kDa subunit)
(CF-1 77 kDa subunit) (CstF-77)
Length = 717
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/148 (33%), Positives = 73/148 (49%)
Frame = +1
Query: 7 TRQMLPFKPKAYPRTGSHXXXXXXXXXXXAASALLRILPPPECFHGPFVQVAKFMEHFLE 186
T+QM+PF+P+ G H AA L+++LPPP CF GPFVQV + ME F
Sbjct: 586 TQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRR 645
Query: 187 LKIPEEYANPPVDENVIIDSGTALSIEMAANAQLMRKRRRISTNNENRESDDETENNLST 366
KIP V+E V I +G A + + N + + + T R ++D E+
Sbjct: 646 CKIPN-----TVEEAVRIITGGAPELAVEGNGPV--ESNAVLTKAVKRPNEDSDEDEEKG 698
Query: 367 SIGGIPTIQAAGGNILDIFRLRQQKKAR 450
++ +P + DI+R RQQK+ R
Sbjct: 699 AV--VPPVH-------DIYRARQQKRIR 717
>sp|Q5RDW9|CSTF3_PONPY Cleavage stimulation factor, 77 kDa subunit (CSTF 77 kDa subunit)
(CF-1 77 kDa subunit) (CstF-77)
Length = 717
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/148 (33%), Positives = 73/148 (49%)
Frame = +1
Query: 7 TRQMLPFKPKAYPRTGSHXXXXXXXXXXXAASALLRILPPPECFHGPFVQVAKFMEHFLE 186
T+QM+PF+P+ G H AA L+++LPPP CF GPFVQV + ME F
Sbjct: 586 TQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRR 645
Query: 187 LKIPEEYANPPVDENVIIDSGTALSIEMAANAQLMRKRRRISTNNENRESDDETENNLST 366
KIP V+E V I +G A + + N + + + T R ++D E+
Sbjct: 646 CKIPN-----TVEEAVRIITGGAPELAVEGNGPV--ESNAVLTKAVKRPNEDSDEDEEKG 698
Query: 367 SIGGIPTIQAAGGNILDIFRLRQQKKAR 450
++ +P + DI+R RQQK+ R
Sbjct: 699 AV--VPPVH-------DIYRARQQKRIR 717
>sp|Q99LI7|CSTF3_MOUSE Cleavage stimulation factor, 77 kDa subunit (CSTF 77 kDa subunit)
(CF-1 77 kDa subunit) (CstF-77)
Length = 717
Score = 73.9 bits (180), Expect = 2e-13
Identities = 49/148 (33%), Positives = 73/148 (49%)
Frame = +1
Query: 7 TRQMLPFKPKAYPRTGSHXXXXXXXXXXXAASALLRILPPPECFHGPFVQVAKFMEHFLE 186
T+QM+PF+P+ G H AA L+++LPPP CF GPFVQV + ME F
Sbjct: 586 TQQMIPFQPRHLAPPGLHPVPGGVFPVPPAAVVLMKLLPPPICFQGPFVQVDELMEIFRR 645
Query: 187 LKIPEEYANPPVDENVIIDSGTALSIEMAANAQLMRKRRRISTNNENRESDDETENNLST 366
KIP V+E V I +G A + + N + + + T R ++D E+
Sbjct: 646 CKIPN-----TVEEAVRIITGGAPELAVEGNGPV--ESSAVLTKAVKRPNEDSDEDEEKG 698
Query: 367 SIGGIPTIQAAGGNILDIFRLRQQKKAR 450
++ +P + DI+R RQQK+ R
Sbjct: 699 AV--VPPVH-------DIYRARQQKRIR 717
>sp|P25991|SUF_DROME Suppressor of forked protein
Length = 733
Score = 65.1 bits (157), Expect = 1e-10
Identities = 46/157 (29%), Positives = 67/157 (42%), Gaps = 13/157 (8%)
Frame = +1
Query: 13 QMLPFKPKAYPRTGSHXXXXXXXXXXXAASALLRILPPPECFHGPFVQVAKFMEHFLELK 192
QM+PFKP+ G+H A +AL LPPP F GPFV V + F+ L
Sbjct: 589 QMIPFKPRPCAHPGAHPLAGGVFPQPPALAALCATLPPPNSFRGPFVSVELLFDIFMRLN 648
Query: 193 IPEEYANPPVDENV-------------IIDSGTALSIEMAANAQLMRKRRRISTNNENRE 333
+P+ P D + I+D+ T ++ + A R+RR + + +
Sbjct: 649 LPDSAPQPNGDNELSPKIFDLAKSVHWIVDTSTYTGVQHSVTAVPPRRRRLLPGGD---D 705
Query: 334 SDDETENNLSTSIGGIPTIQAAGGNILDIFRLRQQKK 444
SDDE +Q A DI+RLRQ K+
Sbjct: 706 SDDE--------------LQTAVPPSHDIYRLRQLKR 728
>sp|O13911|PNK1_SCHPO Bifunctional polynucleotide phosphatase/kinase (Polynucleotide
kinase-3'-phosphatase) (DNA 5'-kinase/3'-phosphatase)
[Includes: Polynucleotide 3'-phosphatase
(2'(3')-polynucleotidase); Polynucleotide
5'-hydroxy-kinase ]
Length = 421
Score = 30.8 bits (68), Expect = 2.0
Identities = 11/27 (40%), Positives = 18/27 (66%)
Frame = +2
Query: 53 VRIQFPEENFLHHQLLQHYFESYHPQN 133
++ + PE+ FL H + FES+HP+N
Sbjct: 211 IKFETPEQFFLGHSFVPPNFESFHPKN 237
>sp|Q8INR6|DOT1L_DROME Histone-lysine N-methyltransferase, H3 lysine-79 specific (Histone
H3-K79 methyltransferase) (H3-K79-HMTase) (Protein
grappa) (DOT1-like protein) (dDOT1L)
Length = 1848
Score = 30.4 bits (67), Expect = 2.7
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Frame = +1
Query: 250 TALSIEMAANAQLMRK--RRRISTNNENRESDDETENNLSTSIGGIPTIQAAGGNILDIF 423
TA + A+N + RK S+ ++ +SDDE ENN S S GG GG++
Sbjct: 464 TATNTTSASNGPMTRKVWSDWCSSKGKSSQSDDE-ENNNSNSNGGSNGGSIGGGSVGRQA 522
Query: 424 RLRQQKKAR 450
R QKK +
Sbjct: 523 RATTQKKRK 531
>sp|Q8SX83|SPEN_DROME Split ends protein
Length = 5560
Score = 29.6 bits (65), Expect = 4.6
Identities = 13/41 (31%), Positives = 22/41 (53%)
Frame = +1
Query: 277 NAQLMRKRRRISTNNENRESDDETENNLSTSIGGIPTIQAA 399
NA KRRR++T + S T ++ + +GGI ++ A
Sbjct: 1199 NASAAAKRRRVTTTMQQPSSSSTTNSSSGSGLGGISSLTPA 1239
>sp|P0A2T6|CRP_SALTY Catabolite gene activator (cAMP receptor protein) (cAMP-regulatory
protein)
sp|P0A2T7|CRP_KLEAE Catabolite gene activator (cAMP receptor protein) (cAMP-regulatory
protein)
Length = 210
Score = 29.3 bits (64), Expect = 6.0
Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
Frame = +2
Query: 332 SLMMRQKTICQLLSEVFQQFRQLVEI---FLISLDSDNKRRL 448
S +R KT C++ +++FRQL+++ L+ L S RRL
Sbjct: 84 SAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSSQMARRL 125
>sp|Q28689|MRP2_RABIT Canalicular multispecific organic anion transporter 1 (ATP-binding
cassette sub-family C member 2) (Multidrug
resistance-associated protein 2) (Canalicular multidrug
resistance protein) (Epithelial basolateral chloride
conductance regulator)
Length = 1564
Score = 29.3 bits (64), Expect = 6.0
Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 16/73 (21%)
Frame = +1
Query: 214 PPVDENVIIDSGTALSIEMAANAQLMRKRRRISTN----------------NENRESDDE 345
P VDE V++++GT L E + + L+ K+ + N N+ E DD+
Sbjct: 824 PQVDEIVVVENGTIL--EKGSYSSLLAKKGVFAKNLKMFVKHTDSEGEVTVNDGSEEDDD 881
Query: 346 TENNLSTSIGGIP 384
++ L +SI P
Sbjct: 882 DDSGLISSIEEFP 894
>sp|P38836|ECM14_YEAST Extracellular matrix protein 14 precursor
Length = 430
Score = 28.9 bits (63), Expect = 7.8
Identities = 17/61 (27%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Frame = +1
Query: 175 HFLELKIPEEYANPPVDENVIIDSGTALSIEMAANAQLMRKRRRISTN------NENRES 336
+F+++K+P+E D VIID+ L +Q+M + + + N NE R+
Sbjct: 65 NFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYDFFFNEYRDL 124
Query: 337 D 339
D
Sbjct: 125 D 125
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,555,753
Number of Sequences: 369166
Number of extensions: 1265315
Number of successful extensions: 3406
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3277
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3396
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3452909250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)