Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02504 (384 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O35625|AXN1_MOUSE Axin-1 (Axis inhibition protein 1) (Fu... 73 2e-13 sp|O15169|AXN1_HUMAN Axin-1 (Axis inhibition protein 1) (hA... 72 3e-13 sp|O70239|AXN1_RAT Axin-1 (Axis inhibition protein 1) (rAxin) 72 4e-13 sp|O42400|AXN_CHICK Axin (Axis inhibition protein) 70 1e-12 sp|Q9YGY0|AXN_XENLA Axin (Axis inhibition protein) (xAxin) 69 3e-12 sp|P57094|AXN1_BRARE Axin-1 (Axis inhibition protein 1) 66 2e-11 sp|Q9V407|AXN_DROME Axin (Axis inhibition protein) (dAxin) ... 65 6e-11 sp|Q9Y2T1|AXN2_HUMAN Axin-2 (Axis inhibition protein 2) (Co... 64 1e-10 sp|P57095|AXN2_BRARE Axin-2 (Axis inhibition protein 2) 63 2e-10 sp|O70240|AXN2_RAT Axin-2 (Axis inhibition protein 2) (Cond... 63 2e-10
>sp|O35625|AXN1_MOUSE Axin-1 (Axis inhibition protein 1) (Fused protein) Length = 863 Score = 72.8 bits (177), Expect = 2e-13 Identities = 38/74 (51%), Positives = 51/74 (68%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +P+PYRT V TLGQFK LL ++G YRY+FK+ DEFD G V EE +E VLP Sbjct: 793 EPIPYRTLVR--GRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEPVLP 849 Query: 182 LWEGKVVAKVEKME 223 ++E K++ KVEK++ Sbjct: 850 VFEEKIIGKVEKVD 863
>sp|O15169|AXN1_HUMAN Axin-1 (Axis inhibition protein 1) (hAxin) Length = 862 Score = 72.4 bits (176), Expect = 3e-13 Identities = 38/74 (51%), Positives = 51/74 (68%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +P+PYRT V TLGQFK LL ++G YRY+FK+ DEFD G V EE +E VLP Sbjct: 792 EPIPYRTLVR--GRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAVLP 848 Query: 182 LWEGKVVAKVEKME 223 ++E K++ KVEK++ Sbjct: 849 VFEEKIIGKVEKVD 862
>sp|O70239|AXN1_RAT Axin-1 (Axis inhibition protein 1) (rAxin) Length = 827 Score = 72.0 bits (175), Expect = 4e-13 Identities = 37/74 (50%), Positives = 51/74 (68%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +P+PYRT V TLGQFK LL ++G YRY+FK+ DEFD G V EE +E +LP Sbjct: 757 EPIPYRTLVR--GRAVTLGQFKELLTKKGSYRYYFKKVSDEFD-CGVVFEEVREDEAILP 813 Query: 182 LWEGKVVAKVEKME 223 ++E K++ KVEK++ Sbjct: 814 VFEEKIIGKVEKVD 827
>sp|O42400|AXN_CHICK Axin (Axis inhibition protein) Length = 841 Score = 70.5 bits (171), Expect = 1e-12 Identities = 36/74 (48%), Positives = 51/74 (68%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +P+PYRT V TLGQFK LL ++G YRY+FK+ DEFD G V EE ++ +LP Sbjct: 771 EPIPYRTLVK--GRVVTLGQFKELLTKKGNYRYYFKKVSDEFD-CGVVFEEVREDDTILP 827 Query: 182 LWEGKVVAKVEKME 223 ++E K++ KVEK++ Sbjct: 828 IFEEKIIGKVEKID 841
>sp|Q9YGY0|AXN_XENLA Axin (Axis inhibition protein) (xAxin) Length = 842 Score = 69.3 bits (168), Expect = 3e-12 Identities = 35/74 (47%), Positives = 51/74 (68%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +P+PYRT V TLGQFK LL ++G YRY+FK+ DEFD G V EE ++ +LP Sbjct: 772 EPIPYRTMVK--GRVVTLGQFKELLTKKGNYRYYFKKVSDEFD-CGVVFEEVREDDMILP 828 Query: 182 LWEGKVVAKVEKME 223 ++E K++ +VEK++ Sbjct: 829 IYEEKIIGQVEKID 842
>sp|P57094|AXN1_BRARE Axin-1 (Axis inhibition protein 1) Length = 835 Score = 66.2 bits (160), Expect = 2e-11 Identities = 34/74 (45%), Positives = 50/74 (67%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +P+PYRT V TLGQFK LL ++G Y+Y+FK+ EFD G V EE ++ +LP Sbjct: 765 EPIPYRTSVK--GRIVTLGQFKELLTKKGSYKYYFKKVSYEFD-CGVVFEEVREDDAILP 821 Query: 182 LWEGKVVAKVEKME 223 ++E K++ KVEK++ Sbjct: 822 IFEEKIIGKVEKVD 835
>sp|Q9V407|AXN_DROME Axin (Axis inhibition protein) (dAxin) (d-Axin) Length = 745 Score = 64.7 bits (156), Expect = 6e-11 Identities = 33/71 (46%), Positives = 46/71 (64%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 +PVPYR ++P T TL QFK LPRRG +R+FFK HC++ D +QEE + D+LP Sbjct: 675 EPVPYRIKIP--GTQPTLRQFKDYLPRRGHFRFFFKTHCEDPD-SPVIQEEIVNDSDILP 731 Query: 182 LWEGKVVAKVE 214 L+ K + V+ Sbjct: 732 LFGDKAMGLVK 742
>sp|Q9Y2T1|AXN2_HUMAN Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil) Length = 843 Score = 63.5 bits (153), Expect = 1e-10 Identities = 32/74 (43%), Positives = 48/74 (64%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 + +PYR + TLG FK L ++G YRY+FK+ DEF GAV EE +E VLP Sbjct: 773 EEIPYRRMLKA--QSLTLGHFKEQLSKKGNYRYYFKKASDEF-ACGAVFEEIWEDETVLP 829 Query: 182 LWEGKVVAKVEKME 223 ++EG+++ KVE+++ Sbjct: 830 MYEGRILGKVERID 843
>sp|P57095|AXN2_BRARE Axin-2 (Axis inhibition protein 2) Length = 812 Score = 62.8 bits (151), Expect = 2e-10 Identities = 34/74 (45%), Positives = 48/74 (64%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 + +PYR + TLG FK L ++G YRYFFKR DEF+ GAV EE + VLP Sbjct: 742 EEIPYRRMMKTHS--LTLGHFKEQLRKKGNYRYFFKRASDEFE-CGAVFEEVWDDCTVLP 798 Query: 182 LWEGKVVAKVEKME 223 ++EGK++ KV++M+ Sbjct: 799 MYEGKILGKVDRMD 812
>sp|O70240|AXN2_RAT Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil) Length = 838 Score = 62.8 bits (151), Expect = 2e-10 Identities = 32/74 (43%), Positives = 48/74 (64%) Frame = +2 Query: 2 DPVPYRTQVPCGDTGFTLGQFKMLLPRRGPYRYFFKRHCDEFDGGGAVQEEYTRNEDVLP 181 + +PYR + TLG FK L ++G YRY+FK+ DEF GAV EE +E VLP Sbjct: 768 EEIPYRRMLKA--QSLTLGHFKEQLSKKGNYRYYFKKASDEF-ACGAVFEEIWDDETVLP 824 Query: 182 LWEGKVVAKVEKME 223 ++EG+++ KVE+++ Sbjct: 825 MYEGRILGKVERID 838
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 48,168,141 Number of Sequences: 369166 Number of extensions: 916590 Number of successful extensions: 1856 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1820 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1843 length of database: 68,354,980 effective HSP length: 94 effective length of database: 50,989,890 effective search space used: 1682666370 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)