Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02476
(866 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UHI7|S23A1_HUMAN Solute carrier family 23 member 1 (So... 142 9e-34
sp|Q9Z2J0|S23A1_MOUSE Solute carrier family 23 member 1 (So... 142 2e-33
sp|Q9WTW7|S23A1_RAT Solute carrier family 23 member 1 (Sodi... 141 2e-33
sp|Q9WTW8|S23A2_RAT Solute carrier family 23 member 2 (Sodi... 137 3e-32
sp|Q9EPR4|S23A2_MOUSE Solute carrier family 23 member 2 (So... 137 3e-32
sp|Q9UGH3|S23A2_HUMAN Solute carrier family 23 member 2 (So... 137 4e-32
sp|O32140|PUCK_BACSU Uric acid permease pucK 68 3e-11
sp|P50487|Y397_CLOPE Putative purine permease CPE0397 66 1e-10
sp|Q46821|YGFU_ECOLI Putative purine permease ygfU 63 9e-10
sp|P42086|PBUX_BACSU Xanthine permease 62 3e-09
>sp|Q9UHI7|S23A1_HUMAN Solute carrier family 23 member 1 (Sodium-dependent vitamin C
transporter 1) (hSVCT1) (Na(+)/L-ascorbic acid
transporter 1) (Yolk sac permease-like molecule 3)
Length = 598
Score = 142 bits (359), Expect = 9e-34
Identities = 79/231 (34%), Positives = 127/231 (54%), Gaps = 1/231 (0%)
Frame = +1
Query: 13 APKVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIM 192
AP P AINRGIF EGI ++G LG + TS S NIG++ ITK G+ R+ Q A IM
Sbjct: 348 APPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIM 407
Query: 193 ILFGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSF 372
++ G F ALF S+PDP +GG+ + ++ ++N Q++DM S+RN+ + GFS+ F
Sbjct: 408 LVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFF 467
Query: 373 GLTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPGYYYGEKDKAI 552
GLT P + S+ + G +D+++ +LLT +F+ A LDN +P G ++
Sbjct: 468 GLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVP----GSPEERG 523
Query: 553 SICGTECVKAYTEFERHL-AFDLKILKWLAIKCQCLQFLPLFPAYRNLKES 702
I A ++ L ++D I + + L+++P+ P ++ S
Sbjct: 524 LIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSS 574
>sp|Q9Z2J0|S23A1_MOUSE Solute carrier family 23 member 1 (Sodium-dependent vitamin C
transporter 1) (Na(+)/L-ascorbic acid transporter 1)
(Yolk sac permease-like molecule 3)
Length = 605
Score = 142 bits (357), Expect = 2e-33
Identities = 70/170 (41%), Positives = 104/170 (61%)
Frame = +1
Query: 13 APKVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIM 192
AP P AINRGIF EGI ++G LG + TS S NIG++ ITK G+ R+ Q A IM
Sbjct: 355 APPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIM 414
Query: 193 ILFGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSF 372
++ G F ALF S+PDP +GG+ + ++ ++N Q++DM S+RN+ + GFS+ F
Sbjct: 415 LILGAIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFF 474
Query: 373 GLTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPG 522
GLT P + S+ + G +D+++ +LLT +F+ A LDN +PG
Sbjct: 475 GLTLPNYLDSNPGAINTGIPEVDQILTVLLTTEMFVGGCLAFILDNTVPG 524
>sp|Q9WTW7|S23A1_RAT Solute carrier family 23 member 1 (Sodium-dependent vitamin C
transporter 1) (Na(+)/L-ascorbic acid transporter 1)
Length = 604
Score = 141 bits (356), Expect = 2e-33
Identities = 69/170 (40%), Positives = 104/170 (61%)
Frame = +1
Query: 13 APKVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIM 192
AP P AINRGIF EG+ ++G LG + TS S NIG++ ITK G+ R+ Q A IM
Sbjct: 355 APPPPVHAINRGIFTEGVCCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIM 414
Query: 193 ILFGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSF 372
++ G F ALF S+PDP +GG+ + ++ ++N Q++DM S+RN+ + GFS+ F
Sbjct: 415 LILGAIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFF 474
Query: 373 GLTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPG 522
GLT P + S+ + G +D+++ +LLT +F+ A LDN +PG
Sbjct: 475 GLTLPNYLDSNPGAINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPG 524
>sp|Q9WTW8|S23A2_RAT Solute carrier family 23 member 2 (Sodium-dependent vitamin C
transporter 2) (Na(+)/L-ascorbic acid transporter 2)
Length = 592
Score = 137 bits (346), Expect = 3e-32
Identities = 80/225 (35%), Positives = 124/225 (55%), Gaps = 1/225 (0%)
Frame = +1
Query: 13 APKVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIM 192
AP P AINRGIF+EG+ L G G + TS S NIG++ ITK G+ R+ Q A +M
Sbjct: 349 APPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALM 408
Query: 193 ILFGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSF 372
+ G+ F ALF S+PDP +G + + ++ ++N Q+ID+ S+RN+ + GFS+ F
Sbjct: 409 LGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFF 468
Query: 373 GLTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPGYYYGEKDKAI 552
GL P++ + L G ID+V+++LLT +F+ A LDN +PG K
Sbjct: 469 GLVLPSYLRQ--NPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKW 526
Query: 553 SICGTECVKAYTEFERH-LAFDLKILKWLAIKCQCLQFLPLFPAY 684
++ K+ E + L F + I+K K +C +LP+ P +
Sbjct: 527 KKGVSKGNKSLDGMESYNLPFGMNIIK----KYRCFSYLPISPTF 567
>sp|Q9EPR4|S23A2_MOUSE Solute carrier family 23 member 2 (Sodium-dependent vitamin C
transporter 2) (mSVCT2) (Na(+)/L-ascorbic acid
transporter 2) (Yolk sac permease-like molecule 2)
Length = 647
Score = 137 bits (346), Expect = 3e-32
Identities = 79/225 (35%), Positives = 124/225 (55%), Gaps = 1/225 (0%)
Frame = +1
Query: 13 APKVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIM 192
AP P AINRGIF+EG+ L G G + TS S NIG++ ITK G+ R+ Q A +M
Sbjct: 404 APPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALM 463
Query: 193 ILFGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSF 372
+ G+ F ALF S+PDP +G + + ++ ++N Q+ID+ S+RN+ + GFS+ F
Sbjct: 464 LGLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFF 523
Query: 373 GLTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPGYYYGEKDKAI 552
GL P++ + L G ID+++++LLT +F+ A LDN +PG K
Sbjct: 524 GLVLPSYLRQ--NPLVTGITGIDQILNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKW 581
Query: 553 SICGTECVKAYTEFERH-LAFDLKILKWLAIKCQCLQFLPLFPAY 684
++ K+ E + L F + I+K K +C +LP+ P +
Sbjct: 582 KKGVSKGSKSLDGMESYNLPFGMNIIK----KYRCFSYLPISPTF 622
>sp|Q9UGH3|S23A2_HUMAN Solute carrier family 23 member 2 (Sodium-dependent vitamin C
transporter 2) (hSVCT2) (Na(+)/L-ascorbic acid
transporter 2) (Yolk sac permease-like molecule 2)
(Nucleobase transporter-like 1 protein)
Length = 650
Score = 137 bits (345), Expect = 4e-32
Identities = 76/224 (33%), Positives = 122/224 (54%)
Frame = +1
Query: 13 APKVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIM 192
AP P AINRGIF+EG+ L G G + TS S NIG++ ITK G+ R+ Q A +M
Sbjct: 407 APPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALM 466
Query: 193 ILFGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSF 372
+ G+ F ALF S+PDP +G + + ++ ++N Q+ID+ S+RN+ + GFS+ F
Sbjct: 467 LALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFF 526
Query: 373 GLTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPGYYYGEKDKAI 552
GL P++ + L G ID+V+++LLT +F+ A LDN +PG +++ I
Sbjct: 527 GLVLPSYLRQ--NPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPG---TPEERGI 581
Query: 553 SICGTECVKAYTEFERHLAFDLKILKWLAIKCQCLQFLPLFPAY 684
K + +++L + K +C +LP+ P +
Sbjct: 582 RKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTF 625
>sp|O32140|PUCK_BACSU Uric acid permease pucK
Length = 430
Score = 68.2 bits (165), Expect = 3e-11
Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 3/125 (2%)
Frame = +1
Query: 37 INRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIMILFGIFPV 216
+ +G EG+ + L G A T++S N+G+++++K +V + +T I++ G+ P
Sbjct: 268 LEKGYRAEGLAILLGGLFNAFPY-TAFSQNVGIVQLSKMKSVNVIAITGIILVAIGLVPK 326
Query: 217 FGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSFGL---TFP 387
AL IP P +GG + ++ +V+ I +D+ S N++I SVS GL T P
Sbjct: 327 AAALTTVIPTPVLGGAMIVMFGMVISYGIKMLSSVDLDSQGNLLIIASSVSLGLGATTVP 386
Query: 388 TWCSS 402
SS
Sbjct: 387 ALFSS 391
>sp|P50487|Y397_CLOPE Putative purine permease CPE0397
Length = 452
Score = 65.9 bits (159), Expect = 1e-10
Identities = 35/112 (31%), Positives = 60/112 (53%), Gaps = 1/112 (0%)
Frame = +1
Query: 46 GIFIEGIGVFLSGFLGAVSCP-TSYSGNIGLMKITKAGNVRIGQVTAFIMILFGIFPVFG 222
G+ +G+G L G +G SCP TS+S NIG++ +TK + + + ++++ G P
Sbjct: 286 GVLSDGVGSALGGLVG--SCPNTSFSQNIGIISLTKVASRHVAVMAGILLVILGFLPKVA 343
Query: 223 ALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSFGL 378
A+ IP+P +GGV ++ V I I + + RN++I S+ GL
Sbjct: 344 AIITGIPNPVLGGVGIMMFGTVAAAGIRTLSNIKL-TERNLLIIAISMGLGL 394
>sp|Q46821|YGFU_ECOLI Putative purine permease ygfU
Length = 482
Score = 63.2 bits (152), Expect = 9e-10
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 1/172 (0%)
Frame = +1
Query: 19 KVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIMIL 198
K+ I RG+ ++G+G + G + TS+S N+GL+ +T+ + + + I+IL
Sbjct: 285 KLSSHDIIRGLRVDGVGTMIGGTFNSFP-HTSFSQNVGLVSVTRVHSRWVCISSGIILIL 343
Query: 199 FGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTR-NIVIYGFSVSFG 375
FG+ P L SIP +GG ++ +VL I + + R N+ I S+ G
Sbjct: 344 FGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVG 403
Query: 376 LTFPTWCSSHLDLLTVGYQPIDEVIHILLTIHLFIAAVTAIFLDNVLPGYYY 531
+T PT L QP LL + +A ++A+ L+ GY +
Sbjct: 404 MT-PTLSHDFFSKLPAVLQP-------LLHSGIMLATLSAVVLNVFFNGYQH 447
>sp|P42086|PBUX_BACSU Xanthine permease
Length = 438
Score = 61.6 bits (148), Expect = 3e-09
Identities = 35/120 (29%), Positives = 59/120 (49%)
Frame = +1
Query: 19 KVPQFAINRGIFIEGIGVFLSGFLGAVSCPTSYSGNIGLMKITKAGNVRIGQVTAFIMIL 198
++ + +++G EG+ V L G A T++S N+GL+++T + VT I++
Sbjct: 260 RLTEIDLSKGYRAEGLAVLLGGIFNAFPY-TAFSQNVGLVQLTGIKKNAVIVVTGVILMA 318
Query: 199 FGIFPVFGALFVSIPDPAVGGVLFIVCLLVLGCAINNFQYIDMYSTRNIVIYGFSVSFGL 378
FG+FP A IP +GG + + +V+ I ID N++I SV GL
Sbjct: 319 FGLFPKIAAFTTIIPSAVLGGAMVAMFGMVIAYGIKMLSRIDFAKQENLLIVACSVGLGL 378
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,803,309
Number of Sequences: 369166
Number of extensions: 2051987
Number of successful extensions: 5563
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5352
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5557
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)