Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02474
(925 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43347|MSI1H_HUMAN RNA-binding protein Musashi homolog 1... 120 5e-27
sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2... 120 5e-27
sp|Q96DH6|MSI2H_HUMAN RNA-binding protein Musashi homolog 2... 120 5e-27
sp|Q8K3P4|MSI1H_RAT RNA-binding protein Musashi homolog 1 (... 118 2e-26
sp|Q61474|MSI1H_MOUSE RNA-binding protein Musashi homolog 1... 118 2e-26
sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprote... 78 4e-14
sp|P17132|HNRPC_RAT Heterogeneous nuclear ribonucleoprotein... 78 4e-14
sp|Q9JJ54|HNRPD_RAT Heterogeneous nuclear ribonucleoprotein... 78 4e-14
sp|Q60668|HNRPD_MOUSE Heterogeneous nuclear ribonucleoprote... 78 4e-14
sp|P51990|RO22_XENLA Heterogeneous nuclear ribonucleoprotei... 77 5e-14
>sp|O43347|MSI1H_HUMAN RNA-binding protein Musashi homolog 1 (Musashi-1)
Length = 362
Score = 120 bits (301), Expect = 5e-27
Identities = 50/80 (62%), Positives = 68/80 (85%)
Frame = +3
Query: 15 RTKKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQI 194
RTKKIF+GG++ ++TVE+++QYF ++G+V++ LM DK TNRHRGFGFVTF ED+ E++
Sbjct: 107 RTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
Query: 195 CQIHYHNINNKMVEAKKALP 254
C+IH+H INNKMVE KKA P
Sbjct: 167 CEIHFHEINNKMVECKKAQP 186
Score = 75.1 bits (183), Expect = 3e-13
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ +T E +R+YF ++GEV+ C +M D T R RGFGFVTF+D+ +++
Sbjct: 21 KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
Query: 204 HYHNINNKMVEAKKALP 254
H +++K ++ K A P
Sbjct: 81 SRHELDSKTIDPKVAFP 97
>sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2 (Musashi-2)
Length = 346
Score = 120 bits (301), Expect = 5e-27
Identities = 51/80 (63%), Positives = 68/80 (85%)
Frame = +3
Query: 15 RTKKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQI 194
RTKKIF+GG++ ++ VE+++QYF ++G+VE+ LM DK TNRHRGFGFVTF +EDV E++
Sbjct: 108 RTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 167
Query: 195 CQIHYHNINNKMVEAKKALP 254
C+IH+H INNKMVE KKA P
Sbjct: 168 CEIHFHEINNKMVECKKAQP 187
Score = 72.0 bits (175), Expect = 2e-12
Identities = 29/77 (37%), Positives = 50/77 (64%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ ++ + +R YF+++GE+ C +M D T R RGFGFVTF D +++
Sbjct: 22 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
Query: 204 HYHNINNKMVEAKKALP 254
+H +++K ++ K A P
Sbjct: 82 PHHELDSKTIDPKVAFP 98
>sp|Q96DH6|MSI2H_HUMAN RNA-binding protein Musashi homolog 2 (Musashi-2)
Length = 328
Score = 120 bits (301), Expect = 5e-27
Identities = 51/80 (63%), Positives = 68/80 (85%)
Frame = +3
Query: 15 RTKKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQI 194
RTKKIF+GG++ ++ VE+++QYF ++G+VE+ LM DK TNRHRGFGFVTF +EDV E++
Sbjct: 108 RTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 167
Query: 195 CQIHYHNINNKMVEAKKALP 254
C+IH+H INNKMVE KKA P
Sbjct: 168 CEIHFHEINNKMVECKKAQP 187
Score = 72.0 bits (175), Expect = 2e-12
Identities = 29/77 (37%), Positives = 50/77 (64%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ ++ + +R YF+++GE+ C +M D T R RGFGFVTF D +++
Sbjct: 22 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
Query: 204 HYHNINNKMVEAKKALP 254
+H +++K ++ K A P
Sbjct: 82 PHHELDSKTIDPKVAFP 98
>sp|Q8K3P4|MSI1H_RAT RNA-binding protein Musashi homolog 1 (Musashi-1)
Length = 362
Score = 118 bits (296), Expect = 2e-26
Identities = 49/80 (61%), Positives = 67/80 (83%)
Frame = +3
Query: 15 RTKKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQI 194
RTKKIF+GG++ ++TVE+++ YF ++G+V++ LM DK TNRHRGFGFVTF ED+ E++
Sbjct: 107 RTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
Query: 195 CQIHYHNINNKMVEAKKALP 254
C+IH+H INNKMVE KKA P
Sbjct: 167 CEIHFHEINNKMVECKKAQP 186
Score = 75.1 bits (183), Expect = 3e-13
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ +T E +R+YF ++GEV+ C +M D T R RGFGFVTF+D+ +++
Sbjct: 21 KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
Query: 204 HYHNINNKMVEAKKALP 254
H +++K ++ K A P
Sbjct: 81 SRHELDSKTIDPKVAFP 97
>sp|Q61474|MSI1H_MOUSE RNA-binding protein Musashi homolog 1 (Musashi-1)
Length = 362
Score = 118 bits (296), Expect = 2e-26
Identities = 49/80 (61%), Positives = 67/80 (83%)
Frame = +3
Query: 15 RTKKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQI 194
RTKKIF+GG++ ++TVE+++ YF ++G+V++ LM DK TNRHRGFGFVTF ED+ E++
Sbjct: 107 RTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKV 166
Query: 195 CQIHYHNINNKMVEAKKALP 254
C+IH+H INNKMVE KKA P
Sbjct: 167 CEIHFHEINNKMVECKKAQP 186
Score = 75.1 bits (183), Expect = 3e-13
Identities = 32/77 (41%), Positives = 52/77 (67%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ +T E +R+YF ++GEV+ C +M D T R RGFGFVTF+D+ +++
Sbjct: 21 KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQ 80
Query: 204 HYHNINNKMVEAKKALP 254
H +++K ++ K A P
Sbjct: 81 SRHELDSKTIDPKVAFP 97
>sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich
element RNA-binding protein 1)
Length = 355
Score = 77.8 bits (190), Expect = 4e-14
Identities = 35/77 (45%), Positives = 52/77 (67%)
Frame = +3
Query: 21 KKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQ 200
KKIF+GG++ + E+IR+YF +GEVE+ EL MD TN+ RGF F+TF +E+ ++I +
Sbjct: 182 KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIME 241
Query: 201 IHYHNINNKMVEAKKAL 251
YHN+ E K A+
Sbjct: 242 KKYHNVGLSKCEIKVAM 258
Score = 71.2 bits (173), Expect = 4e-12
Identities = 28/75 (37%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ +T ++++ YF+++GEV +C L +D T R RGFGFV F + + +++
Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 157
Query: 204 HYHNINNKMVEAKKA 248
H +N K+++ K+A
Sbjct: 158 KEHKLNGKVIDPKRA 172
>sp|P17132|HNRPC_RAT Heterogeneous nuclear ribonucleoprotein C (hnRNP C) (hnRNP core
protein C)
Length = 158
Score = 77.8 bits (190), Expect = 4e-14
Identities = 35/77 (45%), Positives = 52/77 (67%)
Frame = +3
Query: 21 KKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQ 200
KKIF+GG++ + E+IR+YF +GEVE+ EL MD TN+ RGF F+TF +E+ ++I +
Sbjct: 34 KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIME 93
Query: 201 IHYHNINNKMVEAKKAL 251
YHN+ E K A+
Sbjct: 94 KKYHNVGLSKCEIKVAM 110
>sp|Q9JJ54|HNRPD_RAT Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich
element RNA-binding protein 1)
Length = 353
Score = 77.8 bits (190), Expect = 4e-14
Identities = 35/77 (45%), Positives = 52/77 (67%)
Frame = +3
Query: 21 KKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQ 200
KKIF+GG++ + E+IR+YF +GEVE+ EL MD TN+ RGF F+TF +E+ ++I +
Sbjct: 180 KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIME 239
Query: 201 IHYHNINNKMVEAKKAL 251
YHN+ E K A+
Sbjct: 240 KKYHNVGLSKCEIKVAM 256
Score = 70.1 bits (170), Expect = 8e-12
Identities = 27/75 (36%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ +T ++++ YF+++G+V +C L +D T R RGFGFV F + + +++
Sbjct: 96 KMFIGGLSWDTTKKDLKDYFSKFGDVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 155
Query: 204 HYHNINNKMVEAKKA 248
H +N K+++ K+A
Sbjct: 156 KEHKLNGKVIDPKRA 170
>sp|Q60668|HNRPD_MOUSE Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich
element RNA-binding protein 1)
Length = 355
Score = 77.8 bits (190), Expect = 4e-14
Identities = 35/77 (45%), Positives = 52/77 (67%)
Frame = +3
Query: 21 KKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQ 200
KKIF+GG++ + E+IR+YF +GEVE+ EL MD TN+ RGF F+TF +E+ ++I +
Sbjct: 182 KKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIME 241
Query: 201 IHYHNINNKMVEAKKAL 251
YHN+ E K A+
Sbjct: 242 KKYHNVGLSKCEIKVAM 258
Score = 71.2 bits (173), Expect = 4e-12
Identities = 28/75 (37%), Positives = 51/75 (68%)
Frame = +3
Query: 24 KIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQI 203
K+FIGG++ +T ++++ YF+++GEV +C L +D T R RGFGFV F + + +++
Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 157
Query: 204 HYHNINNKMVEAKKA 248
H +N K+++ K+A
Sbjct: 158 KEHKLNGKVIDPKRA 172
>sp|P51990|RO22_XENLA Heterogeneous nuclear ribonucleoprotein A2 homolog 2 (hnRNP A2(B))
Length = 358
Score = 77.4 bits (189), Expect = 5e-14
Identities = 34/77 (44%), Positives = 49/77 (63%)
Frame = +3
Query: 21 KKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQ 200
KK+F+GGI + +R+YF YG++E+ E++ DK + + RGFGFVTF D D ++I
Sbjct: 100 KKLFVGGIKEDTEEHHLREYFEEYGKIESTEIITDKQSGKKRGFGFVTFNDHDPVDKIVL 159
Query: 201 IHYHNINNKMVEAKKAL 251
YH IN E +KAL
Sbjct: 160 QKYHTINGHNAEVRKAL 176
Score = 65.9 bits (159), Expect = 2e-10
Identities = 28/77 (36%), Positives = 50/77 (64%)
Frame = +3
Query: 21 KKIFIGGIATSSTVEEIRQYFNRYGEVENCELMMDKATNRHRGFGFVTFLDEDVAEQICQ 200
+K+FIGG++ +T E +R ++ ++G++ +C +M D A+ R RGFGFVTF + +
Sbjct: 9 RKLFIGGLSFETTEESLRNFYEQWGQLTDCVVMRDPASKRSRGFGFVTFSCMNEVDAAMS 68
Query: 201 IHYHNINNKMVEAKKAL 251
H I+ ++VE K+A+
Sbjct: 69 ARPHTIDGRVVEPKRAV 85
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,754,817
Number of Sequences: 369166
Number of extensions: 2009671
Number of successful extensions: 5334
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5027
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5315
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)