Planaria EST Database


DrC_02430

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02430
         (855 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P40126|TYRP2_HUMAN  Dopachrome tautomerase precursor (DT)...    86   1e-16
sp|O93505|TYRP2_CHICK  Dopachrome tautomerase precursor (DT)...    86   1e-16
sp|Q04604|TYRO_RANNI  Tyrosinase precursor (Monophenol monoo...    86   2e-16
sp|P29812|TYRP2_MOUSE  Dopachrome tautomerase precursor (DT)...    85   2e-16
sp|Q8MIU0|TYRO_BOVIN  Tyrosinase precursor (Monophenol monoo...    84   7e-16
sp|P55025|TYRO_ORYLA  Tyrosinase precursor (Monophenol monoo...    80   7e-15
sp|P54834|TYRO_CANFA  Tyrosinase precursor (Monophenol monoo...    80   9e-15
sp|P55028|TYRP1_CARAU  5,6-dihydroxyindole-2-carboxylic acid...    79   1e-14
sp|P55024|TYRO_CHICK  Tyrosinase precursor (Monophenol monoo...    79   2e-14
sp|P11344|TYRO_MOUSE  Tyrosinase precursor (Monophenol monoo...    79   2e-14
>sp|P40126|TYRP2_HUMAN Dopachrome tautomerase precursor (DT) (DCT) (Dopachrome
           delta-isomerase) (Tyrosinase-related protein 2) (TRP-2)
           (TRP2)
          Length = 519

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 55/163 (33%), Positives = 84/163 (51%), Gaps = 5/163 (3%)
 Frame = +1

Query: 25  SVQYMLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIAR 204
           SV    V++H +  R T+       + +  ++F+H+   F TWHRY+++  ER LQ +  
Sbjct: 180 SVYDFFVWLHYYSVRDTLLGPG---RPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRL-- 234

Query: 205 KEFGIKNFALPYWDW-TGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQEPD 381
              G ++FALPYW++ TG+  CD+CTD + GA   R  D   IS  S F +W   C   D
Sbjct: 235 --IGNESFALPYWNFATGRNECDVCTDQLFGAA--RPDDPTLISRNSRFSSWETVC---D 287

Query: 382 NADESPCYGCHVTGTYGKITRE----WNSLEFPTISDVEFVLS 498
           + D+         GTY  + R      NS++ PT+ D+   LS
Sbjct: 288 SLDDYNHLVTLCNGTYEGLLRRNQMGRNSMKLPTLKDIRDCLS 330

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 5/66 (7%)
 Frame = +3

Query: 600 SFHRALEGMCGQPEKA-----SDLFYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDR 764
           SF  ALEG     +KA     S +  +HN +H+ ++G+     +A +DP+F+  H+ TD 
Sbjct: 346 SFRNALEGF----DKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDA 401

Query: 765 IFEVYL 782
           IF+ ++
Sbjct: 402 IFDEWM 407
>sp|O93505|TYRP2_CHICK Dopachrome tautomerase precursor (DT) (DCT) (Dopachrome
           delta-isomerase) (Tyrosinase-related protein 2) (TRP-2)
           (TRP2)
          Length = 521

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 56/162 (34%), Positives = 85/162 (52%), Gaps = 3/162 (1%)
 Frame = +1

Query: 25  SVQYMLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIAR 204
           S+    V++H +  R T+       + F  ++F+H+   F TWHRY+++  ER LQ +  
Sbjct: 182 SIYNYFVWLHYYSVRDTLLGPG---RPFTAIDFSHQGPAFVTWHRYHLLLLERDLQRL-- 236

Query: 205 KEFGIKNFALPYWDW-TGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQEPD 381
              G ++FALPYWD+ TG+ +CD+CTD + GAP  R  D   ISL S F  W   C   D
Sbjct: 237 --MGNESFALPYWDFATGRNTCDVCTDQLFGAP--RPDDPGLISLNSRFSRWQIVCNSLD 292

Query: 382 NADE--SPCYGCHVTGTYGKITREWNSLEFPTISDVEFVLSK 501
           + +   + C G    G   +  R+ +  + PT  DV   LS+
Sbjct: 293 DYNRLVTLCNGSD-EGLLQRRPRD-SGEQLPTAEDVRRCLSR 332

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
 Frame = +3

Query: 600 SFHRALEGMCGQPEKA--SDLFYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFE 773
           SF  ALEG   +PE A  S +  +HN  H+ ++G+      A +DP+F+  H+ TD IF+
Sbjct: 347 SFRNALEGF-NKPEGALNSPMLNLHNLAHSFLNGTRVLPHAAANDPIFVVLHSFTDAIFD 405

Query: 774 VYL 782
            ++
Sbjct: 406 EWM 408
>sp|Q04604|TYRO_RANNI Tyrosinase precursor (Monophenol monooxygenase)
          Length = 532

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 5/159 (3%)
 Frame = +1

Query: 37  MLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIARKEFG 216
           + V+IH + SR    ED      +  ++F HEA GF  WHR+Y++ WER +Q +     G
Sbjct: 179 LFVWIHYYASRDAFLEDG---SVWADIDFAHEAPGFLPWHRFYLLLWEREIQKVT----G 231

Query: 217 IKNFALPYWDWTGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQEPD--NAD 390
             NF +P+WDW     C++CTD+  G  G        +S  S F +W   C  P+  N+ 
Sbjct: 232 DDNFTIPFWDWRDAQQCELCTDEFFG--GTHPTSNNLLSPASFFSSWQIICSRPEEYNSL 289

Query: 391 ESPCYGCH---VTGTYGKITREWNSLEFPTISDVEFVLS 498
              C G +   +  + G+  R   +   PT +DVE  LS
Sbjct: 290 RIICNGTNEGPLLRSPGRHDRN-RTPRLPTSADVEACLS 327

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = +3

Query: 600 SFHRALEGMCGQPEKASDLFY--MHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFE 773
           SF   LEG        ++     MHN +H  ++GSM     + +DP+F+ HH   D +FE
Sbjct: 343 SFRNTLEGFAVPTSGIANRSQSSMHNSLHVFLNGSMSSVQGSANDPIFVLHHAFVDSLFE 402

Query: 774 VYL 782
            +L
Sbjct: 403 QWL 405
>sp|P29812|TYRP2_MOUSE Dopachrome tautomerase precursor (DT) (DCT) (Dopachrome
           delta-isomerase) (Tyrosinase-related protein 2) (TRP-2)
           (TRP2) (SLATY locus protein)
          Length = 517

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 57/166 (34%), Positives = 85/166 (51%), Gaps = 8/166 (4%)
 Frame = +1

Query: 25  SVQYMLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIAR 204
           SV    V++H +  R T+       + +  ++F+H+   F TWHRY++++ ER LQ +  
Sbjct: 180 SVYDFFVWLHYYSVRDTLLGPG---RPYKAIDFSHQGPAFVTWHRYHLLWLERELQRLT- 235

Query: 205 KEFGIKNFALPYWDW-TGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQEPD 381
              G ++FALPYW++ TG+  CD+CTDD  GA   R  D   IS  S F  W   C   D
Sbjct: 236 ---GNESFALPYWNFATGKNECDVCTDDWLGAA--RQDDPTLISRNSRFSTWEIVCDSLD 290

Query: 382 NADESPCYGCHVT---GTYGKITRE----WNSLEFPTISDVEFVLS 498
           +      Y   VT   GTY  + R      N+ + PT+ +V+  LS
Sbjct: 291 D------YNRRVTLCNGTYEGLLRRNKVGRNNEKLPTLKNVQDCLS 330

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
 Frame = +3

Query: 600 SFHRALEGMCGQPEKA-----SDLFYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDR 764
           SF  ALEG     +KA     S +  +HN  H+ ++G+     +A +DP+F+  H+ TD 
Sbjct: 346 SFRNALEGF----DKADGTLDSQVMNLHNLAHSFLNGTNALPHSAANDPVFVVLHSFTDA 401

Query: 765 IFEVYL 782
           IF+ +L
Sbjct: 402 IFDEWL 407
>sp|Q8MIU0|TYRO_BOVIN Tyrosinase precursor (Monophenol monooxygenase)
          Length = 530

 Score = 83.6 bits (205), Expect = 7e-16
 Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 8/166 (4%)
 Frame = +1

Query: 25  SVQYMLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIAR 204
           SV  + V++H + SR T+  D    + +  ++F HEA GF  WHR +++ WE+ +Q +  
Sbjct: 171 SVYDLFVWMHYYVSRDTLLGD---SEVWRDIDFAHEAPGFLPWHRLFLLLWEQEIQKLT- 226

Query: 205 KEFGIKNFALPYWDWTGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQ--EP 378
              G +NF +PYWDW    +CD+CTD+  G  G    +   +S  S F +W   C   E 
Sbjct: 227 ---GDENFTIPYWDWRDAENCDVCTDEYMG--GRNPANPNLLSPASFFSSWQIVCSRLEE 281

Query: 379 DNADESPCYGCHVTGTYGKITR------EWNSLEFPTISDVEFVLS 498
            N+ ++ C G     + G + R      +  +   P+ +DVEF LS
Sbjct: 282 YNSRQALCNGT----SEGPLLRNPGNHDKARTPRLPSSADVEFCLS 323

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
 Frame = +3

Query: 600 SFHRALEGMCGQPEKASDLFY--MHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFE 773
           SF   LEG        +D     MHN +H  ++G+M     + +DP+F+ HH   D IFE
Sbjct: 339 SFRNTLEGFADPVTGIADASQSSMHNALHIYMNGTMSQVPGSANDPIFLLHHAFVDSIFE 398

Query: 774 VYL 782
            +L
Sbjct: 399 QWL 401
>sp|P55025|TYRO_ORYLA Tyrosinase precursor (Monophenol monooxygenase)
          Length = 540

 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 54/164 (32%), Positives = 79/164 (48%), Gaps = 8/164 (4%)
 Frame = +1

Query: 37  MLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIARKEFG 216
           + V+IH + SR T      +   +  ++F HE+  F  WHR Y++ WE+ +    RK  G
Sbjct: 177 LFVWIHYYVSRDTFLGGPGNV--WRDIDFAHESAAFLPWHRVYLLHWEQEI----RKITG 230

Query: 217 IKNFALPYWDWTGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFC--QEPDNAD 390
             NF +PYWDW    SC++CTD++ G  G    +   IS  S F +W   C  QE  N  
Sbjct: 231 DFNFTIPYWDWRDAQSCEVCTDNLMG--GRNALNPNLISPASVFSSWKVICTQQEEYNNQ 288

Query: 391 ESPCYGCHVTGTYGKITREWNSLE------FPTISDVEFVLSKP 504
           E+ C         G + R   + +       PT +DVEF +S P
Sbjct: 289 EALCNAT----AEGPLLRNPGNHDPNRVPRIPTTADVEFTISLP 328

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
 Frame = +3

Query: 483 RIRSF*TSVNILFISNLPK--AFNLNRFHVSGERVTDTACESFHRALEGMCGQPEKASDL 656
           R+    T+ ++ F  +LP+    +++RF          A  SF   LEG    PE    +
Sbjct: 311 RVPRIPTTADVEFTISLPEYETGSMDRF----------ANNSFRNVLEGFAS-PETGMAV 359

Query: 657 ---FYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFEVYL 782
                MHN +H  ++GSM     + +DP+F+ HH   D IFE +L
Sbjct: 360 QGQSTMHNALHVFMNGSMSSVQGSANDPIFLLHHAFIDSIFERWL 404
>sp|P54834|TYRO_CANFA Tyrosinase precursor (Monophenol monooxygenase)
          Length = 530

 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 8/162 (4%)
 Frame = +1

Query: 37  MLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIARKEFG 216
           + V++H + SR T+       + +  ++F HEA GF  WHR +++ WE+ +Q +     G
Sbjct: 175 LFVWMHYYVSRDTLLGG---SEIWKDIDFAHEAPGFLPWHRLFLLLWEQEIQKLT----G 227

Query: 217 IKNFALPYWDWTGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQ--EPDNAD 390
            +NF +PYWDW    SCDICTD+  G  G    +   +S  S F +W   C   E  N+ 
Sbjct: 228 DENFTIPYWDWRDAKSCDICTDEYMG--GRNPANPNLLSPASFFSSWQIVCTRLEEYNSR 285

Query: 391 ESPCYG------CHVTGTYGKITREWNSLEFPTISDVEFVLS 498
           ++ C G          G + K      +   P+ +DVEF LS
Sbjct: 286 QALCDGTPEGPLLRNPGNHDKA----RTPRLPSSADVEFCLS 323

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
 Frame = +3

Query: 543 FNLNRFHVSGERVTDTACESFHRALEGMCGQPEKASDLFY--MHNKIHNMIDGSMCCSGT 716
           F L+      + +   A  SF   LEG        +D     MHN +H  ++G+M     
Sbjct: 320 FCLSLTQYESDSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVPG 379

Query: 717 APSDPLFIFHHTQTDRIFEVYL 782
           + +DP+F+ HH   D IFE +L
Sbjct: 380 SANDPIFLLHHAFVDSIFEQWL 401
>sp|P55028|TYRP1_CARAU 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (DHICA
           oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1)
          Length = 522

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 45/123 (36%), Positives = 65/123 (52%), Gaps = 1/123 (0%)
 Frame = +1

Query: 25  SVQYMLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIAR 204
           S+  + V+ H +    T      D  +FG ++F+HE  GF TWHRY+++  ER +Q +  
Sbjct: 173 SIYNLFVWTHYYSVSKTFLGAGQD--SFGGVDFSHEGPGFLTWHRYHLLQLERDMQVM-- 228

Query: 205 KEFGIKNFALPYWDWT-GQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQEPD 381
              G  +FALPYWD+  G + CDICTD++ GA      D   IS  S F  W   C+  +
Sbjct: 229 --LGDPSFALPYWDFAIGGSECDICTDELMGARS--SSDSSSISSNSIFSRWRVICESVE 284

Query: 382 NAD 390
             D
Sbjct: 285 EYD 287

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 21/67 (31%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
 Frame = +3

Query: 588 TACESFHRALEGMCGQPEKASD--LFYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTD 761
           T+ +SF  ++EG    P+   D  +  +HN  H  ++G+   +  +P+DP+F+  HT TD
Sbjct: 340 TSSDSFRNSIEGYSA-PQGNYDPVVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTD 398

Query: 762 RIFEVYL 782
            +F+ +L
Sbjct: 399 AVFDEWL 405
>sp|P55024|TYRO_CHICK Tyrosinase precursor (Monophenol monooxygenase)
          Length = 529

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 51/164 (31%), Positives = 81/164 (49%), Gaps = 6/164 (3%)
 Frame = +1

Query: 25  SVQYMLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIAR 204
           +V  + V++H + SR T+       ++   ++F HEA GF  WHR +++ WER +Q I  
Sbjct: 171 NVYDLFVWMHYYASRDTLLGGSNVWRD---IDFAHEAPGFLPWHRAFLLLWEREIQKIT- 226

Query: 205 KEFGIKNFALPYWDWTGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFCQEPDN 384
              G +NF +PYWDW     C ICTD+  G  G    +   +S  S F +W   C + + 
Sbjct: 227 ---GDENFTIPYWDWRDAEDCVICTDEYMG--GQHPTNPNLLSPASFFSSWQVICTQSEE 281

Query: 385 ADESPCYGCHVTGTYGKITR------EWNSLEFPTISDVEFVLS 498
            +      C+ T + G I R      +  +   P+ S+VEF L+
Sbjct: 282 YNSQQAL-CNAT-SEGPILRNPGNNDKSRTPRLPSSSEVEFCLT 323

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
 Frame = +3

Query: 600 SFHRALEGMCGQPEKASDLFY--MHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFE 773
           SF   LEG        S++    +HN +H  ++GSM     + +DP+FI HH   D IFE
Sbjct: 339 SFRNTLEGFADPHTAISNISQSGLHNALHIYMNGSMSQVQGSANDPIFILHHAFVDSIFE 398

Query: 774 VYL 782
            +L
Sbjct: 399 RWL 401
>sp|P11344|TYRO_MOUSE Tyrosinase precursor (Monophenol monooxygenase) (Albino locus
           protein)
          Length = 533

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 8/162 (4%)
 Frame = +1

Query: 37  MLVFIHRFGSRATMFEDYLDCQNFGILNFNHEAIGFATWHRYYMMFWERLLQDIARKEFG 216
           + V++H + SR T+       + +  ++F HEA GF  WHR +++ WE+ ++++     G
Sbjct: 175 LFVWMHYYVSRDTLLGG---SEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELT----G 227

Query: 217 IKNFALPYWDWTGQTSCDICTDDMAGAPGFRDKDGVRISLRSPFGNWTEFC--QEPDNAD 390
            +NF +PYWDW    +CDICTD+  G  G   ++   +S  S F +W   C   E  N+ 
Sbjct: 228 DENFTVPYWDWRDAENCDICTDEYLG--GRHPENPNLLSPASFFSSWQIICSRSEEYNSH 285

Query: 391 ESPCYG------CHVTGTYGKITREWNSLEFPTISDVEFVLS 498
           +  C G          G + K      +   P+ +DVEF LS
Sbjct: 286 QVLCDGTPEGPLLRNPGNHDKA----KTPRLPSSADVEFCLS 323

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 22/62 (35%), Positives = 34/62 (54%)
 Frame = +3

Query: 597 ESFHRALEGMCGQPEKASDLFYMHNKIHNMIDGSMCCSGTAPSDPLFIFHHTQTDRIFEV 776
           E F   L G+   P ++S    MHN +H  ++G+M     + +DP+F+ HH   D IFE 
Sbjct: 345 EVFASPLTGIA-DPSQSS----MHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQ 399

Query: 777 YL 782
           +L
Sbjct: 400 WL 401
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,651,241
Number of Sequences: 369166
Number of extensions: 2262455
Number of successful extensions: 5357
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5082
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5319
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)