Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02426
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q62377|U2AFM_MOUSE U2 small nuclear ribonucleoprotein au... 119 1e-26
sp|Q64707|U2AFL_MOUSE U2 small nuclear ribonucleoprotein au... 114 2e-25
sp|Q15696|U2AFM_HUMAN U2 small nuclear ribonucleoprotein au... 112 2e-24
sp|Q15695|U2AFL_HUMAN U2 small nuclear ribonucleoprotein au... 112 2e-24
sp|Q09176|U2AF1_SCHPO Splicing factor U2AF 23 kDa subunit (... 84 5e-16
sp|Q01081|U2AF1_HUMAN Splicing factor U2AF 35 kDa subunit (... 79 2e-14
sp|Q9D883|U2AF1_MOUSE Splicing factor U2AF 35 kDa subunit (... 79 2e-14
sp|Q94535|U2AF1_DROME Splicing factor U2af 38 kDa subunit (... 75 2e-13
sp|Q6CEW9|MRD1_YARLI Multiple RNA-binding domain-containing... 40 0.006
sp|Q14498|RNPC2_HUMAN RNA-binding region containing protein... 40 0.008
>sp|Q62377|U2AFM_MOUSE U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit
related-protein 2 (U2(RNU2) small nuclear RNA auxillary
factor 1-like 2)
Length = 462
Score = 119 bits (297), Expect = 1e-26
Identities = 54/122 (44%), Positives = 75/122 (61%)
Frame = +2
Query: 35 DPDLGLEYDENELIGEYEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNIND 214
DPD LE+ E E+ ++ +FY DV EF S G+V+ + N HLRGNVYVQY++ D
Sbjct: 224 DPDSSLEFSEEEIYQQFLDFYYDVLPEFKSVGKVIQFKVSCNLEPHLRGNVYVQYQSEED 283
Query: 215 AVYSFSQLNGRFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESF 394
+FS NGR+YAG +L F + W+ +ICGL+ +CP+G CNF+HV N +
Sbjct: 284 CQAAFSVFNGRWYAGRQLQCEFCPVTRWKMAICGLFEVQQCPRGKHCNFLHVFRNPNNEY 343
Query: 395 RD 400
RD
Sbjct: 344 RD 345
>sp|Q64707|U2AFL_MOUSE U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit
related-protein 1 (U2(RNU2) small nuclear RNA auxillary
factor 1-like 1) (SP2)
Length = 428
Score = 114 bits (286), Expect = 2e-25
Identities = 53/122 (43%), Positives = 72/122 (59%)
Frame = +2
Query: 35 DPDLGLEYDENELIGEYEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNIND 214
D D LEY E E ++ +FY DV EF + G+V+ + N HLRGNVYVQY++ +
Sbjct: 211 DSDANLEYSEEETYQQFLDFYHDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEE 270
Query: 215 AVYSFSQLNGRFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESF 394
+ S NGR+YAG +L F + W+ +ICGL+ KCPKG CNF+HV N F
Sbjct: 271 CQAALSLFNGRWYAGRQLQCEFCPVTRWKVAICGLFEMQKCPKGKHCNFLHVFRNPNNEF 330
Query: 395 RD 400
R+
Sbjct: 331 RE 332
>sp|Q15696|U2AFM_HUMAN U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit
related-protein 2 (U2(RNU2) small nuclear RNA auxillary
factor 1-like 2)
Length = 482
Score = 112 bits (279), Expect = 2e-24
Identities = 51/120 (42%), Positives = 71/120 (59%)
Frame = +2
Query: 35 DPDLGLEYDENELIGEYEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNIND 214
DPD LEY E E ++ +FY DV EF + G+V+ + N HLRGNVYVQY++ +
Sbjct: 220 DPDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEE 279
Query: 215 AVYSFSQLNGRFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESF 394
+ S NGR+YAG +L F + W+ +ICGL+ +CP+G CNF+HV N F
Sbjct: 280 CQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEF 339
>sp|Q15695|U2AFL_HUMAN U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit
related-protein 1 (U2(RNU2) small nuclear RNA auxillary
factor 1-like 1)
Length = 479
Score = 112 bits (279), Expect = 2e-24
Identities = 51/120 (42%), Positives = 71/120 (59%)
Frame = +2
Query: 35 DPDLGLEYDENELIGEYEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNIND 214
DPD LEY E E ++ +FY DV EF + G+V+ + N HLRGNVYVQY++ +
Sbjct: 225 DPDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEE 284
Query: 215 AVYSFSQLNGRFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESF 394
+ S NGR+YAG +L F + W+ +ICGL+ +CP+G CNF+HV N F
Sbjct: 285 CQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEF 344
>sp|Q09176|U2AF1_SCHPO Splicing factor U2AF 23 kDa subunit (U2 auxiliary factor 23 kDa
subunit) (U2 snRNP auxiliary factor small subunit)
(U2AF23)
Length = 216
Score = 84.0 bits (206), Expect = 5e-16
Identities = 40/119 (33%), Positives = 64/119 (53%)
Frame = +2
Query: 47 GLEYDENELIGEYEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNINDAVYS 226
G ++ + EL +++ FY D+ EFS +G V + C N HL GNVYV+++ A +
Sbjct: 61 GKKFTQRELAEQFDAFYEDMFCEFSKYGEVEQLVVCDNVGDHLVGNVYVRFKYEESAQNA 120
Query: 227 FSQLNGRFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESFRDL 403
LN R+Y+ + A + +RE+ C + +C +GG+CNFMH + RDL
Sbjct: 121 IDDLNSRWYSQRPVYAELSPVTDFREACCRQHETSECQRGGLCNFMHAKKPSPQLLRDL 179
>sp|Q01081|U2AF1_HUMAN Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa
subunit) (U2 snRNP auxiliary factor small subunit)
Length = 240
Score = 78.6 bits (192), Expect = 2e-14
Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Frame = +2
Query: 68 ELIGEYEEFYADVEKEFSS-FGRVMTIRTCRNAMRHLRGNVYVQYRNINDAVYSFSQLNG 244
E+ Y+EF+ +V E +G V + C N HL GNVYV++R DA + LN
Sbjct: 73 EMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNN 132
Query: 245 RFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESFRDL 403
R++ G + A + +RE+ C Y G+C +GG CNFMH+ E R+L
Sbjct: 133 RWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRREL 185
>sp|Q9D883|U2AF1_MOUSE Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa
subunit) (U2 snRNP auxiliary factor small subunit)
Length = 239
Score = 78.6 bits (192), Expect = 2e-14
Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Frame = +2
Query: 68 ELIGEYEEFYADVEKEFSS-FGRVMTIRTCRNAMRHLRGNVYVQYRNINDAVYSFSQLNG 244
E+ Y+EF+ +V E +G V + C N HL GNVYV++R DA + LN
Sbjct: 73 EMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNN 132
Query: 245 RFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHVLLNKGESFRDL 403
R++ G + A + +RE+ C Y G+C +GG CNFMH+ E R+L
Sbjct: 133 RWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRREL 185
>sp|Q94535|U2AF1_DROME Splicing factor U2af 38 kDa subunit (U2 auxiliary factor 38 kDa
subunit) (U2 snRNP auxiliary factor small subunit)
Length = 264
Score = 75.5 bits (184), Expect = 2e-13
Identities = 35/104 (33%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
Frame = +2
Query: 62 ENELIGEYEEFYADVEKEFSS-FGRVMTIRTCRNAMRHLRGNVYVQYRNINDAVYSFSQL 238
+ E+ Y+ F+ DV E +G + + C N HL GNVY+++RN DA + + L
Sbjct: 73 DEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAANDL 132
Query: 239 NGRFYAGNRLSARFVTIDSWRESICGLYFRGKCPKGGICNFMHV 370
N R++ G + + + +RE+ C Y G+C + G CNFMH+
Sbjct: 133 NNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHL 176
>sp|Q6CEW9|MRD1_YARLI Multiple RNA-binding domain-containing protein 1
Length = 828
Score = 40.4 bits (93), Expect = 0.006
Identities = 20/71 (28%), Positives = 35/71 (49%)
Frame = +2
Query: 83 YEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNINDAVYSFSQLNGRFYAGN 262
+E DV+K F +FG + T+R + RG + +Y + +A ++ S L G G
Sbjct: 712 FEATKKDVQKLFGAFGSLKTVRVPKKFNSESRGFAFAEYVSAKEAEHAMSALQGTHLLGR 771
Query: 263 RLSARFVTIDS 295
RL ++ D+
Sbjct: 772 RLVLQYAQADA 782
>sp|Q14498|RNPC2_HUMAN RNA-binding region containing protein 2 (Hepatocellular carcinoma
protein 1) (Splicing factor HCC1)
Length = 530
Score = 40.0 bits (92), Expect = 0.008
Identities = 24/77 (31%), Positives = 45/77 (58%)
Frame = +2
Query: 68 ELIGEYEEFYADVEKEFSSFGRVMTIRTCRNAMRHLRGNVYVQYRNINDAVYSFSQLNGR 247
E +G E DV +E + G V+ I +N+ + GNVYV+ +I A+ + + L+GR
Sbjct: 438 EEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQ---GNVYVKCPSIAAAIAAVNALHGR 494
Query: 248 FYAGNRLSARFVTIDSW 298
++AG ++A +V + ++
Sbjct: 495 WFAGKMITAAYVPLPTY 511
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,986,744
Number of Sequences: 369166
Number of extensions: 1693624
Number of successful extensions: 4789
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4598
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4782
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)