Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02347 (792 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O15164|TIF1A_HUMAN Transcription intermediary factor 1-a... 49 1e-05 sp|Q8TDI0|CHD5_HUMAN Chromodomain helicase-DNA-binding prot... 49 1e-05 sp|Q99PP7|TIF1G_MOUSE Transcription intermediary factor 1-g... 49 2e-05 sp|Q9UPN9|TIF1G_HUMAN Transcription intermediary factor 1-g... 49 2e-05 sp|Q64127|TIF1A_MOUSE Transcription intermediary factor 1-a... 49 2e-05 sp|Q6PDQ2|CHD4_MOUSE Chromodomain helicase-DNA-binding prot... 47 5e-05 sp|O15016|TRI66_HUMAN Tripartite motif protein 66 47 5e-05 sp|Q14839|CHD4_HUMAN Chromodomain helicase-DNA-binding prot... 47 5e-05 sp|Q924W6|TRI66_MOUSE Tripartite motif protein 66 46 1e-04 sp|Q62318|TIF1B_MOUSE Transcription intermediary factor 1-b... 45 3e-04
>sp|O15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif protein 24) (RING finger protein 82) Length = 1050 Score = 49.3 bits (116), Expect = 1e-05 Identities = 19/44 (43%), Positives = 27/44 (61%) Frame = +2 Query: 509 FCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 +C+VC G ++CC C +FH CHV L+ PS G+ +CT C Sbjct: 828 WCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPS-GEWICTFC 870
>sp|Q8TDI0|CHD5_HUMAN Chromodomain helicase-DNA-binding protein 5 (CHD-5) Length = 1954 Score = 49.3 bits (116), Expect = 1e-05 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 1/78 (1%) Frame = +2 Query: 419 IKVEKKSDVDQNDEI-CTEMDDFDASADQRRFCSVCNEPGIVVCCSSCELLFHQGCHVSR 595 I+ E K D D+ +E C E +D D FC VC + G ++CC +C +H C Sbjct: 392 IQWEPKDDDDEEEEGGCEEEED-----DHMEFCRVCKDGGELLCCDACPSSYHLHCLNPP 446 Query: 596 LSQLPSTGDCLCTSCVNP 649 L ++P+ G+ LC C P Sbjct: 447 LPEIPN-GEWLCPRCTCP 463
Score = 35.8 bits (81), Expect = 0.14 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Frame = +2 Query: 473 MDDFDA-SADQRRFCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 +DD D D + +C VC + G ++ C +C +H C L + P G C C Sbjct: 332 IDDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPE-GKWSCPHC 387
>sp|Q99PP7|TIF1G_MOUSE Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif protein 33) Length = 1142 Score = 48.9 bits (115), Expect = 2e-05 Identities = 20/44 (45%), Positives = 26/44 (59%) Frame = +2 Query: 509 FCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 +C+VC G ++CC C +FH CHV L PS GD +CT C Sbjct: 904 WCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPS-GDWICTFC 946
>sp|Q9UPN9|TIF1G_HUMAN Transcription intermediary factor 1-gamma (TIF1-gamma) (RET-fused gene 7 protein) (Rfg7 protein) (Tripartite motif protein 33) Length = 1127 Score = 48.9 bits (115), Expect = 2e-05 Identities = 20/44 (45%), Positives = 26/44 (59%) Frame = +2 Query: 509 FCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 +C+VC G ++CC C +FH CHV L PS GD +CT C Sbjct: 889 WCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPS-GDWICTFC 931
>sp|Q64127|TIF1A_MOUSE Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif protein 24) Length = 1051 Score = 48.5 bits (114), Expect = 2e-05 Identities = 19/44 (43%), Positives = 27/44 (61%) Frame = +2 Query: 509 FCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 +C+VC G ++CC C +FH CHV L+ PS G+ +CT C Sbjct: 829 WCAVCQNGGELLCCEKCPKVFHLTCHVPTLTNFPS-GEWICTFC 871
>sp|Q6PDQ2|CHD4_MOUSE Chromodomain helicase-DNA-binding protein 4 (CHD-4) Length = 1915 Score = 47.4 bits (111), Expect = 5e-05 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Frame = +2 Query: 419 IKVEKKSDVDQNDEICTEM--DDFDASADQRRFCSVCNEPGIVVCCSSCELLFHQGCHVS 592 I+ E K D + +EI E+ D + FC VC + G ++CC +C +H C Sbjct: 412 IQWEAKEDNSEGEEILEEVGGDPEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNP 471 Query: 593 RLSQLPSTGDCLCTSCVNP 649 L ++P+ G+ LC C P Sbjct: 472 PLPEIPN-GEWLCPRCTCP 489
Score = 38.5 bits (88), Expect = 0.021 Identities = 21/86 (24%), Positives = 38/86 (44%) Frame = +2 Query: 383 GYTEFGNAVEHKIKVEKKSDVDQNDEICTEMDDFDASADQRRFCSVCNEPGIVVCCSSCE 562 G T + K++ KK + +E T +D ++ D + +C VC + G ++ C +C Sbjct: 327 GSTSRSSRSRKKLRTAKKKK--KGEEEVTAVDGYET--DHQDYCEVCQQGGEIILCDTCP 382 Query: 563 LLFHQGCHVSRLSQLPSTGDCLCTSC 640 +H C + + P G C C Sbjct: 383 RAYHMVCLDPDMEKAPE-GKWSCPHC 407
>sp|O15016|TRI66_HUMAN Tripartite motif protein 66 Length = 1214 Score = 47.4 bits (111), Expect = 5e-05 Identities = 20/51 (39%), Positives = 27/51 (52%) Frame = +2 Query: 488 ASADQRRFCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 A + FC+VC G ++CC C +FH CHV L P G+ +CT C Sbjct: 963 APIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPG-GEWVCTLC 1012
>sp|Q14839|CHD4_HUMAN Chromodomain helicase-DNA-binding protein 4 (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta) Length = 1912 Score = 47.4 bits (111), Expect = 5e-05 Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 2/79 (2%) Frame = +2 Query: 419 IKVEKKSDVDQNDEICTEMD-DFDASADQR-RFCSVCNEPGIVVCCSSCELLFHQGCHVS 592 I+ E K D + +EI E+ D + D FC VC + G ++CC +C +H C Sbjct: 419 IQWEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNP 478 Query: 593 RLSQLPSTGDCLCTSCVNP 649 L ++P+ G+ LC C P Sbjct: 479 PLPEIPN-GEWLCPRCTCP 496
Score = 38.5 bits (88), Expect = 0.021 Identities = 21/86 (24%), Positives = 38/86 (44%) Frame = +2 Query: 383 GYTEFGNAVEHKIKVEKKSDVDQNDEICTEMDDFDASADQRRFCSVCNEPGIVVCCSSCE 562 G T + K++ KK + +E T +D ++ D + +C VC + G ++ C +C Sbjct: 334 GSTSRSSRSRKKLRTTKKKK--KGEEEVTAVDGYET--DHQDYCEVCQQGGEIILCDTCP 389 Query: 563 LLFHQGCHVSRLSQLPSTGDCLCTSC 640 +H C + + P G C C Sbjct: 390 RAYHMVCLDPDMEKAPE-GKWSCPHC 414
>sp|Q924W6|TRI66_MOUSE Tripartite motif protein 66 Length = 1209 Score = 46.2 bits (108), Expect = 1e-04 Identities = 19/51 (37%), Positives = 27/51 (52%) Frame = +2 Query: 488 ASADQRRFCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 A + FC+VC G ++CC C ++H CHV L P G+ +CT C Sbjct: 958 APIENEDFCAVCINGGELLCCDRCPKVYHLSCHVPALLSFPG-GEWVCTLC 1007
>sp|Q62318|TIF1B_MOUSE Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif protein 28) (KRAB-A interacting protein) (KRIP-1) Length = 834 Score = 44.7 bits (104), Expect = 3e-04 Identities = 18/48 (37%), Positives = 25/48 (52%) Frame = +2 Query: 497 DQRRFCSVCNEPGIVVCCSSCELLFHQGCHVSRLSQLPSTGDCLCTSC 640 D C VC +PG +V C+ CE FH CH+ L +P + C+ C Sbjct: 623 DSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGE-EWSCSLC 669
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,725,979 Number of Sequences: 369166 Number of extensions: 1826409 Number of successful extensions: 6212 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5846 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6202 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7425705210 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)