Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02324
(187 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein) 44 9e-05
sp|Q9GLE3|CATK_PIG Cathepsin K precursor 44 9e-05
sp|P61277|CATK_MACMU Cathepsin K precursor >gi|47117667|sp|... 44 1e-04
sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (C... 44 1e-04
sp|Q9QZE3|CATQ_RAT Cathepsin Q precursor 42 3e-04
sp|P55097|CATK_MOUSE Cathepsin K precursor 42 4e-04
sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (C... 42 4e-04
sp|O35186|CATK_RAT Cathepsin K precursor 41 0.001
sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor 41 0.001
sp|O70370|CATS_MOUSE Cathepsin S precursor 41 0.001
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
Length = 329
Score = 44.3 bits (103), Expect = 9e-05
Identities = 28/61 (45%), Positives = 39/61 (63%), Gaps = 1/61 (1%)
Frame = +2
Query: 5 VVSHATLHQPTINAQLNNEWDTFELLFKKEYDPFV-EIVRRLIWQENLIYIQKHILEADL 181
VVS A LH I L+ +W+ ++ + K+Y+ V EI RRLIW++NL +I H LEA L
Sbjct: 11 VVSFA-LHPEEI---LDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASL 66
Query: 182 G 184
G
Sbjct: 67 G 67
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
Length = 330
Score = 44.3 bits (103), Expect = 9e-05
Identities = 21/46 (45%), Positives = 33/46 (71%), Gaps = 1/46 (2%)
Frame = +2
Query: 50 LNNEWDTFELLFKKEYDPFV-EIVRRLIWQENLIYIQKHILEADLG 184
L+ +W+ ++ ++K+Y+ V EI RRLIW++NL +I H LEA LG
Sbjct: 23 LDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNLEASLG 68
>sp|P61277|CATK_MACMU Cathepsin K precursor
sp|P61276|CATK_MACFA Cathepsin K precursor
Length = 329
Score = 43.9 bits (102), Expect = 1e-04
Identities = 22/46 (47%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Frame = +2
Query: 50 LNNEWDTFELLFKKEYDPFV-EIVRRLIWQENLIYIQKHILEADLG 184
L+ W+ ++ +K+Y+ V EI RRLIW++NL YI H LEA LG
Sbjct: 22 LDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLG 67
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
Length = 329
Score = 43.5 bits (101), Expect = 1e-04
Identities = 22/46 (47%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Frame = +2
Query: 50 LNNEWDTFELLFKKEYDPFV-EIVRRLIWQENLIYIQKHILEADLG 184
L+ W+ ++ +K+Y+ V EI RRLIW++NL YI H LEA LG
Sbjct: 22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLG 67
>sp|Q9QZE3|CATQ_RAT Cathepsin Q precursor
Length = 343
Score = 42.4 bits (98), Expect = 3e-04
Identities = 16/50 (32%), Positives = 33/50 (66%)
Frame = +2
Query: 38 INAQLNNEWDTFELLFKKEYDPFVEIVRRLIWQENLIYIQKHILEADLGK 187
++ L+ +W +++ ++K Y P E+++R++W+EN+ I+ H E LGK
Sbjct: 21 LDLSLDVQWQEWKIKYEKLYSPEEEVLKRVVWEENVKKIELHNRENSLGK 70
>sp|P55097|CATK_MOUSE Cathepsin K precursor
Length = 329
Score = 42.0 bits (97), Expect = 4e-04
Identities = 21/46 (45%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Frame = +2
Query: 50 LNNEWDTFELLFKKEYDPFV-EIVRRLIWQENLIYIQKHILEADLG 184
L+ +W+ ++ +K+Y+ V EI RRLIW++NL I H LEA LG
Sbjct: 22 LDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLG 67
>sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (Catlrp-p)
Length = 333
Score = 42.0 bits (97), Expect = 4e-04
Identities = 23/61 (37%), Positives = 33/61 (54%)
Frame = +2
Query: 5 VVSHATLHQPTINAQLNNEWDTFELLFKKEYDPFVEIVRRLIWQENLIYIQKHILEADLG 184
V S A H P ++A EW ++ + K Y P E +RR +W+EN+ I+ H E LG
Sbjct: 14 VASGAQAHDPKLDA----EWKDWKTKYAKSYSP-EEALRRAVWEENMRMIKLHNKENSLG 68
Query: 185 K 187
K
Sbjct: 69 K 69
>sp|O35186|CATK_RAT Cathepsin K precursor
Length = 329
Score = 40.8 bits (94), Expect = 0.001
Identities = 26/61 (42%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = +2
Query: 5 VVSHATLHQPTINAQLNNEWDTFELLFKKEYDPFV-EIVRRLIWQENLIYIQKHILEADL 181
VVS A + T++ Q W+ ++ K+Y+ V EI RRLIW++NL I H LEA L
Sbjct: 11 VVSFALSPEETLDTQ----WELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASL 66
Query: 182 G 184
G
Sbjct: 67 G 67
>sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor
Length = 334
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/52 (32%), Positives = 31/52 (59%)
Frame = +2
Query: 32 PTINAQLNNEWDTFELLFKKEYDPFVEIVRRLIWQENLIYIQKHILEADLGK 187
P +++ L+ EW +++ + K Y E ++R++W+E L I+ H E LGK
Sbjct: 19 PVLDSSLDAEWQDWKIKYNKSYSLKEEKLKRVVWEEKLKMIKLHNRENSLGK 70
>sp|O70370|CATS_MOUSE Cathepsin S precursor
Length = 340
Score = 40.8 bits (94), Expect = 0.001
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +2
Query: 5 VVSHATLHQPTINAQLNNEWDTFELLFKKEY-DPFVEIVRRLIWQENLIYIQKHILEADL 181
+V + Q + L+ WD ++ +KEY D E VRRLIW++NL +I H LE +
Sbjct: 17 LVCSVAMEQLQRDPTLDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSM 76
Query: 182 G 184
G
Sbjct: 77 G 77
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,662,833
Number of Sequences: 369166
Number of extensions: 373035
Number of successful extensions: 964
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 950
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 962
length of database: 68,354,980
effective HSP length: 34
effective length of database: 62,073,990
effective search space used: 1675997730
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)