Planaria EST Database


DrC_02294

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02294
         (891 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8WWI5|CTL1_HUMAN  Choline transporter-like protein 1 (CD...   114   3e-25
sp|Q9I9B9|CTL1_TORMA  Choline transporter-like protein 1          114   4e-25
sp|Q6X893|CTL1_MOUSE  Choline transporter-like protein 1 (So...   110   4e-24
sp|Q8VII6|CTL1_RAT  Choline transporter-like protein 1 (Solu...   110   4e-24
sp|Q8N4M1|CTL3_HUMAN  Choline transporter-like protein 3 (So...    87   5e-17
sp|Q921V7|CTL3_MOUSE  Choline transporter-like protein 3 (So...    79   1e-14
sp|Q6AY92|CTL3_RAT  Choline transporter-like protein 3 (Solu...    77   6e-14
sp|Q810F1|CTL2_CAVPO  Choline transporter-like protein 2 (So...    64   4e-10
sp|Q8BY89|CTL2_MOUSE  Choline transporter-like protein 2 (So...    62   2e-09
sp|Q8IWA5|CTL2_HUMAN  Choline transporter-like protein 2 (So...    58   4e-08
>sp|Q8WWI5|CTL1_HUMAN Choline transporter-like protein 1 (CD92 antigen) (CDw92 antigen)
           (Solute carrier family 44 member 1)
          Length = 657

 Score =  114 bits (286), Expect = 3e-25
 Identities = 88/285 (30%), Positives = 132/285 (46%), Gaps = 10/285 (3%)
 Frame = +3

Query: 12  LKREEYYQSP-----CPILPVERQIKLLGF--CIRKNISQIMLNSKFNE--IGGINQIKP 164
           LK  EY  SP     CP LPV     +  F  C   NIS     +KF E  I  ++    
Sbjct: 144 LKPSEYTTSPKSSVLCPKLPVPASAPIPFFHRCAPVNIS---CYAKFAEALITFVSDNSV 200

Query: 165 IFESVVRDFILTWKEIMI-LSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXF 341
           +   +    ++T KEI++ L   SLVLS I++V+IRY++                     
Sbjct: 201 LHRLI--SGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGV 258

Query: 342 LWLCYCTQENVLSLQFKEKMKYLMGDVFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILV 521
           LW  Y  Q          +   +  D  N R+ L  AI +             M KR+ +
Sbjct: 259 LWWLYAKQRRSPKETVTPEQLQIAED--NLRALLIYAISATVFTVILFLIMLVMRKRVAL 316

Query: 522 VTHLFREASRCLGQIPCLLFQPIATLLVLAVYFFYWCITFGFLMSVAGYEINNRTGCVKY 701
              LF  A +    +P L+FQP  T   L +++ YW +T  FL    G  + N  G V++
Sbjct: 317 TIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWVYWIMTLLFL-GTTGSPVQNEQGFVEF 375

Query: 702 LTATFPKYVWFYYLVGLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
             +   +Y+W+Y++VGL+WI+EFILA QQ+ +AG V  +YF ++K
Sbjct: 376 KISGPLQYMWWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK 420
>sp|Q9I9B9|CTL1_TORMA Choline transporter-like protein 1
          Length = 646

 Score =  114 bits (285), Expect = 4e-25
 Identities = 85/270 (31%), Positives = 128/270 (47%), Gaps = 5/270 (1%)
 Frame = +3

Query: 42  CPILPVE--RQIKLLGFCIRKNISQIMLNSKFNEIGGINQIKPIFESVVRDFILTWKEIM 215
           CPILPV+  + I     C+  + S   +N  F  +        + + V+   ++T KEI+
Sbjct: 155 CPILPVKSSKPIPFFHRCVPMD-SGCKIN--FKALTTFVSYNSVLQRVITG-VMTSKEII 210

Query: 216 I-LSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYCTQENVLSLQFK 392
           + L   SLVLS +++V+IRY++                     LW  Y   +  L L   
Sbjct: 211 VGLCLMSLVLSILLMVIIRYISKVLVWILAILTIIGSIGGTAVLWWLYADHKKTLKLDPS 270

Query: 393 EKMKYLMGDVF--NTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREASRCLGQI 566
           +      GDV   N  + L  AI +             M KR+ +   LF  A +    I
Sbjct: 271 Q------GDVAADNVTALLVCAIIATVITVILLLLMLIMRKRVALTIALFHVAGKVFIHI 324

Query: 567 PCLLFQPIATLLVLAVYFFYWCITFGFLMSVAGYEINNRTGCVKYLTATFPKYVWFYYLV 746
           P L+FQ + T L LA ++ YW I    L++ AGY      G V++  +   +Y W Y+LV
Sbjct: 325 PFLIFQSLWTFLALAFFWIYW-IAVLLLLATAGYPQKKDQGYVEFKVSGPLQYTWIYHLV 383

Query: 747 GLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
           GL+WI+EFILA QQ+ IAG V  +YF ++K
Sbjct: 384 GLIWISEFILACQQMTIAGAVVTYYFTRDK 413
>sp|Q6X893|CTL1_MOUSE Choline transporter-like protein 1 (Solute carrier family 44 member
           1)
          Length = 653

 Score =  110 bits (276), Expect = 4e-24
 Identities = 69/216 (31%), Positives = 106/216 (49%), Gaps = 1/216 (0%)
 Frame = +3

Query: 192 ILTWKEIMI-LSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYCTQE 368
           ++T KEI++ L   SLVLS I++V+IRY++                     LW  Y  Q 
Sbjct: 207 VMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTVLVILGSLGGTGVLWWLYAKQR 266

Query: 369 NVLSLQFKEKMKYLMGDVFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREAS 548
                    +   +  D  N R+ L  AI +             M KR+ +   LF  A 
Sbjct: 267 RSPKEAVIPEQLQIAED--NLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAG 324

Query: 549 RCLGQIPCLLFQPIATLLVLAVYFFYWCITFGFLMSVAGYEINNRTGCVKYLTATFPKYV 728
           +    +P L+FQP  T   L +++ YW +T  FL    G  + N  G V+Y  +   +Y+
Sbjct: 325 KVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFL-GTTGSAVQNEQGFVEYKISGPLQYM 383

Query: 729 WFYYLVGLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
           W+Y++VGL+WI+EFILA QQ+ +AG V  +YF ++K
Sbjct: 384 WWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK 419
>sp|Q8VII6|CTL1_RAT Choline transporter-like protein 1 (Solute carrier family 44 member
           1)
          Length = 656

 Score =  110 bits (276), Expect = 4e-24
 Identities = 69/216 (31%), Positives = 106/216 (49%), Gaps = 1/216 (0%)
 Frame = +3

Query: 192 ILTWKEIMI-LSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYCTQE 368
           ++T KEI++ L   SLVLS I++V+IRY++                     LW  Y  Q 
Sbjct: 207 VMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWILTILVILGSLGGTGVLWWLYAKQR 266

Query: 369 NVLSLQFKEKMKYLMGDVFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREAS 548
                    +   +  D  N R+ L  AI +             M KR+ +   LF  A 
Sbjct: 267 RSPKETVIPEQLQIAED--NLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAG 324

Query: 549 RCLGQIPCLLFQPIATLLVLAVYFFYWCITFGFLMSVAGYEINNRTGCVKYLTATFPKYV 728
           +    +P L+FQP  T   L +++ YW +T  FL    G  + N  G V+Y  +   +Y+
Sbjct: 325 KVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFL-GTTGSAVQNEQGFVEYKISGPLQYM 383

Query: 729 WFYYLVGLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
           W+Y++VGL+WI+EFILA QQ+ +AG V  +YF ++K
Sbjct: 384 WWYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK 419
>sp|Q8N4M1|CTL3_HUMAN Choline transporter-like protein 3 (Solute carrier family 44 member
           3)
          Length = 653

 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 77/276 (27%), Positives = 119/276 (43%), Gaps = 9/276 (3%)
 Frame = +3

Query: 36  SPCPILPV--ERQIKLLGFCIRKNISQIMLNSKFNEIGGINQIKPIFESVV--RDFILTW 203
           S CP LPV   +   L   C+ +      L +    I  ++ +  I   ++  RD IL  
Sbjct: 160 SLCPRLPVPPSKSFPLFNRCVPQTPECYSLFASVL-INDVDTLHRILSGIMSGRDTILG- 217

Query: 204 KEIMILSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYCTQENVLSL 383
                L   +L LS  M+   R++ +                    LW  Y    N LS+
Sbjct: 218 -----LCILALALSLAMMFTFRFITTLLVHIFISLVILGLLFVCGVLWWLYYDYTNDLSI 272

Query: 384 QF---KEKMKYLMGDVFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREASRC 554
           +    +E MK ++G           AI S             + KRI +   LF+  ++ 
Sbjct: 273 ELDTERENMKCVLG----------FAIVSTGITAVLLVLIFVLRKRIKLTVELFQITNKA 322

Query: 555 LGQIPCLLFQPIATLLVLAVYFFYWCITFGFLMSV--AGYEINNRTGCVKYLTATFPKYV 728
           +   P LLFQP+ T  +L    F+W +    L+S+  AG       G V+Y   +  +Y+
Sbjct: 323 ISSAPFLLFQPLWTFAIL---IFFWVLWVAVLLSLGTAGAAQVMEGGQVEYKPLSGIRYM 379

Query: 729 WFYYLVGLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
           W Y+L+GL+W +EFILA QQ+ IAG V   YF ++K
Sbjct: 380 WSYHLIGLIWTSEFILACQQMTIAGAVVTCYFNRSK 415
>sp|Q921V7|CTL3_MOUSE Choline transporter-like protein 3 (Solute carrier family 44 member
           3)
          Length = 652

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 2/211 (0%)
 Frame = +3

Query: 210 IMILSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYCTQENVLSLQF 389
           I+ L   +  LS  M+   R++++                    LW  Y    N LS + 
Sbjct: 214 ILGLCVFTFALSLAMLFAFRFISTLLIHIIISLVILGLLFVCGVLWWLYYDYTNDLSTEL 273

Query: 390 KEKMKYLMGDVFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREASRCLGQIP 569
             + +       N    L  AI S             + KRI +   L    ++ +   P
Sbjct: 274 DTEKE-------NMNCMLAFAIISTVVTVLLLALIFTLRKRIKLTVELLHVTNKAISSCP 326

Query: 570 CLLFQPIATLLVLAVYFFYWCITFGFLMSV--AGYEINNRTGCVKYLTATFPKYVWFYYL 743
            LLFQP+ T  +L    F+W +    L+S+  AG       G V+Y   +  +Y+W+Y+L
Sbjct: 327 FLLFQPLWTCAIL---IFFWVLWVAVLLSLGTAGTAQVMEGGQVEYKPLSGIRYMWWYHL 383

Query: 744 VGLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
           +GL+W +EFILA Q++ +AG +   YF +N+
Sbjct: 384 IGLIWTSEFILACQRMTVAGAMVACYFNRNQ 414
>sp|Q6AY92|CTL3_RAT Choline transporter-like protein 3 (Solute carrier family 44 member
           3)
          Length = 604

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 66/281 (23%), Positives = 116/281 (41%), Gaps = 11/281 (3%)
 Frame = +3

Query: 27  YYQSP-----CPILPV--ERQIKLLGFCIRKNIS--QIMLNSKFNEIGGINQIKPIFESV 179
           Y QSP     CP LPV   +   L   CI +      +  +   N+   +++I       
Sbjct: 104 YTQSPSADRLCPRLPVPPSKPFPLFNRCIPQTPECYSLFASVLLNDADALHRI------- 156

Query: 180 VRDFILTWKEIMILSAGSLVLSFIMVVLIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYC 359
           +   +     I+ L A    LS  M+   R++++                     W  Y 
Sbjct: 157 LSGIMAGRDTILGLCAFVFALSLAMLFTFRFISTLLVHIIISLVILGLLFVCGVFWWLYY 216

Query: 360 TQENVLSLQFKEKMKYLMGDVFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFR 539
              N LS +   + +       N +  L  A+ +             + KR+ +   L R
Sbjct: 217 DYTNDLSTELDTEKE-------NMKCMLAFAVITTVVTVVLLALIFTLRKRVKLTVELLR 269

Query: 540 EASRCLGQIPCLLFQPIATLLVLAVYFFYWCITFGFLMSV--AGYEINNRTGCVKYLTAT 713
             ++ + + P LL QP+ T  +L    F+W +    L+S+  AG       G V+Y   +
Sbjct: 270 VTNKAISRCPFLLLQPLWTFAILV---FFWVLWVAVLLSLGTAGTAQVMEGGQVEYKPLS 326

Query: 714 FPKYVWFYYLVGLVWITEFILAGQQIIIAGTVAQWYFLKNK 836
             +Y+W+Y+L+GL+W +EFIL  Q++ +AG +   YF +N+
Sbjct: 327 GIRYLWWYHLIGLIWTSEFILTCQRMTVAGAMVTCYFNRNQ 367
>sp|Q810F1|CTL2_CAVPO Choline transporter-like protein 2 (Solute carrier family 44 member
            2) (Inner ear supporting cell antigen) (IESCA)
          Length = 705

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 65/289 (22%), Positives = 116/289 (40%), Gaps = 41/289 (14%)
 Frame = +3

Query: 93   RKNISQIMLNSKFNEIGGINQIKPIFESVVRDFILTWKEIMILSAGSLVLSFIMVVLIRY 272
            RKNI++++  +K  +  GI + + +   +  D+ ++W  I+I    ++VLS + ++L+R+
Sbjct: 197  RKNITELVEGAK--QANGILEARQLAMRIFEDYTVSWYWIVIGLVIAMVLSLLFIILLRF 254

Query: 273  LASAXXXXXXXXXXXXXXXXXXFLWLCYC-------TQENVLSLQFKEKMKYLMGDVFNT 431
            LA                      ++ Y        +  +VL L F+   +  +      
Sbjct: 255  LAGIMVWVMIVLVILVLGYGIFHCYMEYARLRGEAGSDISVLDLGFQTDFRVYL---HLR 311

Query: 432  RSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREASRCLGQIPCLLFQPIATLLVLA 611
            +++L   I               + KRIL+   L +EASR +G + C L  P+ T  +L 
Sbjct: 312  QTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLC 371

Query: 612  VYFFYWCITFGFL--MSVAGYEINNRTGCVKYLTATFPKYVW----------------FY 737
            +   YW  T  FL   + A Y+I   + C        P+  +                FY
Sbjct: 372  LCIAYWASTAVFLSTSNEAVYKILGDSSCPHQGQTCHPETFFNSTEAHACPNARCQFAFY 431

Query: 738  --------YLVGL--------VWITEFILAGQQIIIAGTVAQWYFLKNK 836
                     L+GL         W+  F+LA  Q+ +AG  A +Y+   K
Sbjct: 432  GGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRK 480
>sp|Q8BY89|CTL2_MOUSE Choline transporter-like protein 2 (Solute carrier family 44 member
            2)
          Length = 704

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 63/293 (21%), Positives = 117/293 (39%), Gaps = 41/293 (13%)
 Frame = +3

Query: 81   GFCIRKNISQIMLNSKFNEIGGINQIKPIFESVVRDFILTWKEIMILSAGSLVLSFIMVV 260
            G   RKNI+ ++  +K  +   I + + +   +  D+ ++W  I+I    ++VLS + +V
Sbjct: 192  GHGARKNITDLVEGAK--KANKILEARQLAMQIFEDYTVSWYWIIIGLVIAMVLSLLFIV 249

Query: 261  LIRYLASAXXXXXXXXXXXXXXXXXXFLWLCYC-------TQENVLSLQFKEKMKYLMGD 419
            L+R+LA                      ++ Y        +  +++ L F+  ++  +  
Sbjct: 250  LLRFLAGIMVWVMIVMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDLRVYL-- 307

Query: 420  VFNTRSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREASRCLGQIPCLLFQPIATL 599
                ++++   I               + KRIL+   L +EASR +G + C L  P+ T 
Sbjct: 308  -HLRQTWMAFMIILSILEVVIILLLIFLRKRILIAIALIKEASRAVGHVMCSLLYPLVTF 366

Query: 600  LVLAVYFFYWCITFGFL--MSVAGYEINNRTGCVKYLTA----TFP-------------- 719
             +L +   YW  T  FL   + A Y++ + T C          TFP              
Sbjct: 367  FLLCLCIAYWASTSVFLSTSNTAVYKVVDDTACPLLRKTCNPETFPLRNESLQCPTARCQ 426

Query: 720  ------KYVWFYYLVGL--------VWITEFILAGQQIIIAGTVAQWYFLKNK 836
                  +  +   L+GL         W+  F+LA  Q+ +AG  A +Y+   K
Sbjct: 427  FAFYGGESTYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWAMRK 479
>sp|Q8IWA5|CTL2_HUMAN Choline transporter-like protein 2 (Solute carrier family 44 member
            2)
          Length = 706

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 63/291 (21%), Positives = 119/291 (40%), Gaps = 43/291 (14%)
 Frame = +3

Query: 93   RKNISQIMLNSKFNEIGGINQIKPIFESVVRDFILTWKEIMILSAGSLVLSFIMVVLIRY 272
            RKNI+ ++  +K  +  G+ + + +   +  D+ ++W  I+I    ++ +S + ++L+R+
Sbjct: 198  RKNITDLVEGAK--KANGVLEARQLAMRIFEDYTVSWYWIIIGLVIAMAMSLLFIILLRF 255

Query: 273  LASAXXXXXXXXXXXXXXXXXXFLWLCYC-------TQENVLSLQFKEKMKYLMGDVFNT 431
            LA                      ++ Y        +  +++ L F+   +  +      
Sbjct: 256  LAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDFRVYL---HLR 312

Query: 432  RSFLYMAIGSXXXXXXXXXXXXXMWKRILVVTHLFREASRCLGQIPCLLFQPIATLLVLA 611
            +++L   I               + KRIL+   L +EASR +G + C L  P+ T  +L 
Sbjct: 313  QTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLC 372

Query: 612  VYFFYWCITFGFL--MSVAGYEINNRTGCVKYLTA------TFP-----------KYVWF 734
            +   YW  T  FL   + A Y+I + + C    TA      TFP           +  + 
Sbjct: 373  LCIAYWASTAVFLSTSNEAVYKIFDDSPCP--FTAKTCNPETFPSSNESRQCPNARCQFA 430

Query: 735  YY---------LVGL--------VWITEFILAGQQIIIAGTVAQWYFLKNK 836
            +Y         L+GL         W+  F+LA  Q+ +AG  A +Y+   K
Sbjct: 431  FYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRK 481
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,921,564
Number of Sequences: 369166
Number of extensions: 2026670
Number of successful extensions: 4844
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4667
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4827
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)