Planaria EST Database


DrC_02260

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02260
         (795 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Y0H4|SUDX_DROME  E3 ubiquitin-protein ligase suppressor...   268   2e-71
sp|Q96J02|ITCH_HUMAN  Itchy homolog E3 ubiquitin protein lig...   253   4e-67
sp|Q8C863|ITCH_MOUSE  Itchy E3 ubiquitin protein ligase           253   4e-67
sp|Q9H0M0|WWP1_HUMAN  NEDD4-like E3 ubiquitin-protein ligase...   252   9e-67
sp|Q9DBH0|WWP2_MOUSE  NEDD4-like E3 ubiquitin-protein ligase...   252   9e-67
sp|Q8BZZ3|WWP1_MOUSE  NEDD4-like E3 ubiquitin-protein ligase...   252   9e-67
sp|O00308|WWP2_HUMAN  NEDD4-like E3 ubiquitin-protein ligase...   250   3e-66
sp|Q5RBF2|NED4L_PONPY  E3 ubiquitin-protein ligase NEDD4-lik...   207   3e-53
sp|Q8CFI0|NED4L_MOUSE  E3 ubiquitin-protein ligase NEDD4-lik...   207   3e-53
sp|Q96PU5|NED4L_HUMAN  E3 ubiquitin-protein ligase NEDD4-lik...   207   3e-53
>sp|Q9Y0H4|SUDX_DROME E3 ubiquitin-protein ligase suppressor of deltex
          Length = 949

 Score =  268 bits (684), Expect = 2e-71
 Identities = 119/184 (64%), Positives = 153/184 (83%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            EVLG++  HEL   G + +VT+ENK+EYI LM  W +T+G+E+Q K FLEG  E+VPL  
Sbjct: 756  EVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEW 815

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            L+ FDERELEL+LCG+Q +DV+DW+R+T+YR Y+ ++ QVVWFW+FVR  D+E++ARLLQ
Sbjct: 816  LKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQ 875

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCR+P+GGF+EL G NG Q FC+E+VG ETWLPRSHTCFNRLDLPPY++YDQ VEK
Sbjct: 876  FVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEK 935

Query: 543  LSLA 554
            L+ A
Sbjct: 936  LTFA 939
>sp|Q96J02|ITCH_HUMAN Itchy homolog E3 ubiquitin protein ligase (Itch)
            (Atrophin-1-interacting protein 4) (AIP4)
            (NFE2-associated polypeptide 1) (NAPP1)
          Length = 903

 Score =  253 bits (646), Expect = 4e-67
 Identities = 108/184 (58%), Positives = 149/184 (80%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E+LGE+K H+L P G  + VT+ENK+EYI+++  W L++GVE+Q + F EG  EI+P   
Sbjct: 710  EILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQY 769

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            LQ FD +ELE+LLCG+Q+ID++DW+RH +YR Y+ ++ Q++WFW+FV+ +D+E++ RLLQ
Sbjct: 770  LQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQ 829

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCRLP+GGF++L G NG Q FC+E+VG E WLPRSHTCFNRLDLPPY++Y+Q  EK
Sbjct: 830  FVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEK 889

Query: 543  LSLA 554
            L  A
Sbjct: 890  LLFA 893
>sp|Q8C863|ITCH_MOUSE Itchy E3 ubiquitin protein ligase
          Length = 864

 Score =  253 bits (646), Expect = 4e-67
 Identities = 108/184 (58%), Positives = 149/184 (80%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E+LGE+K H+L P G  + VT+ENK+EYI+++  W L++GVE+Q + F EG  EI+P   
Sbjct: 671  EILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQY 730

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            LQ FD +ELE+LLCG+Q+ID++DW+RH +YR Y+ ++ Q++WFW+FV+ +D+E++ RLLQ
Sbjct: 731  LQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQ 790

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCRLP+GGF++L G NG Q FC+E+VG E WLPRSHTCFNRLDLPPY++Y+Q  EK
Sbjct: 791  FVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEK 850

Query: 543  LSLA 554
            L  A
Sbjct: 851  LLFA 854
>sp|Q9H0M0|WWP1_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP1 (WW domain-containing
            protein 1) (Atropin-1 interacting protein 5) (AIP5)
          Length = 922

 Score =  252 bits (643), Expect = 9e-67
 Identities = 111/184 (60%), Positives = 148/184 (80%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E+LG+V  H+L  GG+ + VT+ENK EYI LM  W  ++GV++Q K FL+G  E+VPL  
Sbjct: 729  EILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQW 788

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            LQ FDE+ELE++LCG+Q++D+ DW+R+TVYR Y+ ++ Q++WFW+FV+  D+E + RLLQ
Sbjct: 789  LQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQ 848

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCRLPLGGF+EL G NG Q FC+E+VG +TWLPRSHTCFNRLDLPPY++Y+Q  EK
Sbjct: 849  FVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEK 908

Query: 543  LSLA 554
            L  A
Sbjct: 909  LLFA 912
>sp|Q9DBH0|WWP2_MOUSE NEDD4-like E3 ubiquitin-protein ligase WWP2 (WW domain-containing
            protein 2)
          Length = 870

 Score =  252 bits (643), Expect = 9e-67
 Identities = 110/184 (59%), Positives = 147/184 (79%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E+LG+V  HEL  GG  ++VT+ENK+EYI L+  W  T+GVE+Q K FL+G  E+ PL  
Sbjct: 677  EILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEW 736

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            L+ FDE+ELEL+LCG+Q+ID+ DW+++ +YR Y+ S+ Q+ WFW+ V+ +D+E++ RLLQ
Sbjct: 737  LRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQ 796

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCRLP+GGF+EL G NG Q FC++RVG ETWLPRSHTCFNRLDLPPY++Y+Q  EK
Sbjct: 797  FVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEK 856

Query: 543  LSLA 554
            L  A
Sbjct: 857  LLYA 860
>sp|Q8BZZ3|WWP1_MOUSE NEDD4-like E3 ubiquitin-protein ligase WWP1 (WW domain-containing
            protein 1)
          Length = 918

 Score =  252 bits (643), Expect = 9e-67
 Identities = 111/184 (60%), Positives = 148/184 (80%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E+LG+V  H+L  GG+ + VT+ENK EYI LM  W  ++GV++Q K FL+G  E+VPL  
Sbjct: 725  EILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQW 784

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            LQ FDE+ELE++LCG+Q++D+ DW+R+TVYR Y+ ++ Q++WFW+FV+  D+E + RLLQ
Sbjct: 785  LQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQ 844

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCRLPLGGF+EL G NG Q FC+E+VG +TWLPRSHTCFNRLDLPPY++Y+Q  EK
Sbjct: 845  FVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEK 904

Query: 543  LSLA 554
            L  A
Sbjct: 905  LLFA 908
>sp|O00308|WWP2_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP2 (WW domain-containing
            protein 2) (Atrophin-1-interacting protein 2) (AIP2)
          Length = 870

 Score =  250 bits (639), Expect = 3e-66
 Identities = 109/184 (59%), Positives = 147/184 (79%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E+LG+V  HEL  GG  ++VT+ENK+EYI L+  W  T+GVE+Q K FL+G  E+ PL  
Sbjct: 677  EILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEW 736

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQYSPSNIQVVWFWKFVRSLDHEQQARLLQ 362
            L+ FDE+ELEL+LCG+Q+ID+ DW++ T+YR Y+ ++ Q+ WFW+ V+ +D+E++ RLLQ
Sbjct: 737  LRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQ 796

Query: 363  FVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVEK 542
            FVTGTCRLP+GGF+EL G NG Q FC+++VG ETWLPRSHTCFNRLDLPPY++Y+Q  EK
Sbjct: 797  FVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREK 856

Query: 543  LSLA 554
            L  A
Sbjct: 857  LLYA 860
>sp|Q5RBF2|NED4L_PONPY E3 ubiquitin-protein ligase NEDD4-like protein
          Length = 959

 Score =  207 bits (527), Expect = 3e-53
 Identities = 97/185 (52%), Positives = 132/185 (71%), Gaps = 1/185 (0%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E  G+    +L P G+E+ VT+ENK+EYI L+I W     V+KQM  FLEG  E++P+ L
Sbjct: 764  ENFGQTYQVDLEPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDL 823

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQ-YSPSNIQVVWFWKFVRSLDHEQQARLL 359
            ++ FDE ELELL+CGL  +DV+DW +H++Y+  Y P++  + WFWK V  +D E++ RLL
Sbjct: 824  IKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLL 883

Query: 360  QFVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVE 539
            QFVTGT R+P+ GF+EL G NG QLF +E+ G    LPR+HTCFNRLDLPPY T++   E
Sbjct: 884  QFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLRE 943

Query: 540  KLSLA 554
            KL +A
Sbjct: 944  KLLMA 948
>sp|Q8CFI0|NED4L_MOUSE E3 ubiquitin-protein ligase NEDD4-like protein (Nedd4-2) (NEDD4.2)
          Length = 1004

 Score =  207 bits (527), Expect = 3e-53
 Identities = 97/185 (52%), Positives = 132/185 (71%), Gaps = 1/185 (0%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E  G+    +L P G+E+ VT+ENK+EYI L+I W     V+KQM  FLEG  E++P+ L
Sbjct: 809  ENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDL 868

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQ-YSPSNIQVVWFWKFVRSLDHEQQARLL 359
            ++ FDE ELELL+CGL  +DV+DW +H++Y+  Y P++  + WFWK V  +D E++ RLL
Sbjct: 869  IKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLL 928

Query: 360  QFVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVE 539
            QFVTGT R+P+ GF+EL G NG QLF +E+ G    LPR+HTCFNRLDLPPY T++   E
Sbjct: 929  QFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLRE 988

Query: 540  KLSLA 554
            KL +A
Sbjct: 989  KLLMA 993
>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like protein (Nedd4-2) (NEDD4.2)
          Length = 975

 Score =  207 bits (527), Expect = 3e-53
 Identities = 97/185 (52%), Positives = 132/185 (71%), Gaps = 1/185 (0%)
 Frame = +3

Query: 3    EVLGEVKLHELIPGGNEVKVTDENKKEYIQLMIPWWLTKGVEKQMKNFLEGLYEIVPLSL 182
            E  G+    +L P G+E+ VT+ENK+EYI L+I W     V+KQM  FLEG  E++P+ L
Sbjct: 780  ENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDL 839

Query: 183  LQRFDERELELLLCGLQKIDVDDWERHTVYRQ-YSPSNIQVVWFWKFVRSLDHEQQARLL 359
            ++ FDE ELELL+CGL  +DV+DW +H++Y+  Y P++  + WFWK V  +D E++ RLL
Sbjct: 840  IKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLL 899

Query: 360  QFVTGTCRLPLGGFSELQGGNGRQLFCLERVGDETWLPRSHTCFNRLDLPPYRTYDQFVE 539
            QFVTGT R+P+ GF+EL G NG QLF +E+ G    LPR+HTCFNRLDLPPY T++   E
Sbjct: 900  QFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLRE 959

Query: 540  KLSLA 554
            KL +A
Sbjct: 960  KLLMA 964
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,391,480
Number of Sequences: 369166
Number of extensions: 1767308
Number of successful extensions: 4467
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4286
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4417
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7473924075
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)