Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02254
(322 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P48987|ATO_DROME Atonal protein 69 4e-12
sp|P59101|SCX_CHICK Basic helix-loop-helix transcription fa... 65 5e-11
sp|P48985|ATOH1_MOUSE Atonal protein homolog 1 (Helix-loop-... 64 1e-10
sp|Q5IS79|ATOH1_PANTR Atonal protein homolog 1 63 2e-10
sp|Q92858|ATOH1_HUMAN Atonal protein homolog 1 (Helix-loop-... 63 2e-10
sp|Q64124|SCX_MOUSE Basic helix-loop-helix transcription fa... 62 3e-10
sp|Q9Y0A7|AMOS_DROME Basic helix-loop-helix transcription f... 62 5e-10
sp|Q7RTS1|MIST1_HUMAN Basic helix-loop-helix protein MIST1 ... 60 1e-09
sp|Q15784|NDF2_HUMAN Neurogenic differentiation factor 2 (N... 60 2e-09
sp|Q62414|NDF2_MOUSE Neurogenic differentiation factor 2 (N... 60 2e-09
>sp|P48987|ATO_DROME Atonal protein
Length = 312
Score = 68.6 bits (166), Expect = 4e-12
Identities = 38/73 (52%), Positives = 51/73 (69%), Gaps = 4/73 (5%)
Frame = +1
Query: 25 SGKPKRRRTTTV----EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLR 192
SGK +R + T ++R AAN RERRRM NLN+AFDRLRQ +P ++QLS+ ETL+
Sbjct: 239 SGKKRRGKQITPVVKRKRRLAANARERRRMQNLNQAFDRLRQYLPCLGNDRQLSKHETLQ 298
Query: 193 LAITYISFMTEQL 231
+A TYIS + + L
Sbjct: 299 MAQTYISALGDLL 311
>sp|P59101|SCX_CHICK Basic helix-loop-helix transcription factor scleraxis
Length = 187
Score = 65.1 bits (157), Expect = 5e-11
Identities = 35/70 (50%), Positives = 45/70 (64%)
Frame = +1
Query: 25 SGKPKRRRTTTVEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAIT 204
SGK R QRH AN RER R N++N AF LR L+PT +++LS+IETLRLA +
Sbjct: 55 SGKKAGRLHREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASS 114
Query: 205 YISFMTEQLI 234
YIS + L+
Sbjct: 115 YISHLGNVLL 124
>sp|P48985|ATOH1_MOUSE Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1)
Length = 351
Score = 63.9 bits (154), Expect = 1e-10
Identities = 31/63 (49%), Positives = 48/63 (76%)
Frame = +1
Query: 61 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQLINA 240
++R AAN RERRRM+ LN AFD+LR ++P+F +K+LS+ ETL++A YI+ ++E L+
Sbjct: 156 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSE-LLQT 214
Query: 241 PEI 249
P +
Sbjct: 215 PNV 217
>sp|Q5IS79|ATOH1_PANTR Atonal protein homolog 1
Length = 356
Score = 63.2 bits (152), Expect = 2e-10
Identities = 30/57 (52%), Positives = 45/57 (78%)
Frame = +1
Query: 61 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 231
++R AAN RERRRM+ LN AFD+LR ++P+F +K+LS+ ETL++A YI+ ++E L
Sbjct: 161 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL 217
>sp|Q92858|ATOH1_HUMAN Atonal protein homolog 1 (Helix-loop-helix protein hATH-1)
Length = 354
Score = 63.2 bits (152), Expect = 2e-10
Identities = 30/57 (52%), Positives = 45/57 (78%)
Frame = +1
Query: 61 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYISFMTEQL 231
++R AAN RERRRM+ LN AFD+LR ++P+F +K+LS+ ETL++A YI+ ++E L
Sbjct: 159 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL 215
>sp|Q64124|SCX_MOUSE Basic helix-loop-helix transcription factor scleraxis
Length = 207
Score = 62.4 bits (150), Expect = 3e-10
Identities = 34/69 (49%), Positives = 45/69 (65%)
Frame = +1
Query: 28 GKPKRRRTTTVEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITY 207
G+P R QRH AN RER R N++N AF LR L+PT +++LS+IETLRLA +Y
Sbjct: 71 GRPGREP----RQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSY 126
Query: 208 ISFMTEQLI 234
IS + L+
Sbjct: 127 ISHLGNVLL 135
>sp|Q9Y0A7|AMOS_DROME Basic helix-loop-helix transcription factor Amos (Reduced olfactory
organs protein) (Rough eye protein) (Absent MD neurons
and olfactory sensilla protein) (Amos protein)
Length = 198
Score = 61.6 bits (148), Expect = 5e-10
Identities = 28/50 (56%), Positives = 41/50 (82%)
Frame = +1
Query: 61 EQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYI 210
++R AAN RERRRMN+LN AFD+LR +VP+ ++++LS+ ETL++A YI
Sbjct: 138 KRRLAANARERRRMNSLNDAFDKLRDVVPSLGHDRRLSKYETLQMAQAYI 187
>sp|Q7RTS1|MIST1_HUMAN Basic helix-loop-helix protein MIST1 (Muscle, intestine and stomach
expression 1)
Length = 189
Score = 60.5 bits (145), Expect = 1e-09
Identities = 29/67 (43%), Positives = 46/67 (68%)
Frame = +1
Query: 34 PKRRRTTTVEQRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRLAITYIS 213
P RR +++++R +N RER+RM+ LN AF LR+++P +K+LS+IETL LA YI
Sbjct: 66 PGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYIK 125
Query: 214 FMTEQLI 234
+T ++
Sbjct: 126 SLTATIL 132
>sp|Q15784|NDF2_HUMAN Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related
factor) (NDRF)
Length = 382
Score = 60.1 bits (144), Expect = 2e-09
Identities = 33/72 (45%), Positives = 47/72 (65%), Gaps = 6/72 (8%)
Frame = +1
Query: 34 PKRRRTTTVE------QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRL 195
PK+R+ T +R AN RER RM++LN A D LR++VP ++ ++LS+IETLRL
Sbjct: 106 PKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRL 165
Query: 196 AITYISFMTEQL 231
A YI ++E L
Sbjct: 166 AKNYIWALSEIL 177
>sp|Q62414|NDF2_MOUSE Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related
factor) (NDRF)
Length = 383
Score = 60.1 bits (144), Expect = 2e-09
Identities = 33/72 (45%), Positives = 47/72 (65%), Gaps = 6/72 (8%)
Frame = +1
Query: 34 PKRRRTTTVE------QRHAANIRERRRMNNLNKAFDRLRQLVPTFAYEKQLSRIETLRL 195
PK+R+ T +R AN RER RM++LN A D LR++VP ++ ++LS+IETLRL
Sbjct: 107 PKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRL 166
Query: 196 AITYISFMTEQL 231
A YI ++E L
Sbjct: 167 AKNYIWALSEIL 178
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,586,029
Number of Sequences: 369166
Number of extensions: 438488
Number of successful extensions: 1565
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1540
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1562
length of database: 68,354,980
effective HSP length: 75
effective length of database: 54,499,855
effective search space used: 1689495505
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)