Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02244 (410 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9XT18|SGK1_RABIT Serine/threonine-protein kinase Sgk1 (... 66 3e-11 sp|Q9WVC6|SGK1_MOUSE Serine/threonine-protein kinase Sgk1 (... 65 7e-11 sp|Q06226|SGK1_RAT Serine/threonine-protein kinase Sgk1 (Se... 65 7e-11 sp|O08874|PKN2_RAT Protein kinase N2 (Protein kinase C-like... 63 3e-10 sp|O00141|SGK1_HUMAN Serine/threonine-protein kinase Sgk1 (... 62 3e-10 sp|Q8BWW9|PKN2_MOUSE Protein kinase N2 (Protein kinase C-li... 62 3e-10 sp|Q16513|PKN2_HUMAN Protein kinase N2 (Protein kinase C-li... 61 8e-10 sp|Q9HBY8|SGK2_HUMAN Serine/threonine-protein kinase Sgk2 (... 57 1e-08 sp|Q96BR1|SGK3_HUMAN Serine/threonine-protein kinase Sgk3 (... 56 2e-08 sp|Q9ERE3|SGK3_MOUSE Serine/threonine-protein kinase Sgk3 (... 56 3e-08
>sp|Q9XT18|SGK1_RABIT Serine/threonine-protein kinase Sgk1 (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 65.9 bits (159), Expect = 3e-11 Identities = 30/57 (52%), Positives = 39/57 (68%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPISGSFPNS 173 DF EI+NH FF+L W LI+K+I PPF P+VS +D+R+ DPEF EP+ S S Sbjct: 345 DFMEIRNHVFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRS 401
>sp|Q9WVC6|SGK1_MOUSE Serine/threonine-protein kinase Sgk1 (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 64.7 bits (156), Expect = 7e-11 Identities = 30/57 (52%), Positives = 39/57 (68%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPISGSFPNS 173 DF EIK+H FF+L W LI+K+I PPF P+VS +D+R+ DPEF EP+ S S Sbjct: 345 DFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRS 401
>sp|Q06226|SGK1_RAT Serine/threonine-protein kinase Sgk1 (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 64.7 bits (156), Expect = 7e-11 Identities = 30/57 (52%), Positives = 39/57 (68%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPISGSFPNS 173 DF EIK+H FF+L W LI+K+I PPF P+VS +D+R+ DPEF EP+ S S Sbjct: 344 DFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRS 400
>sp|O08874|PKN2_RAT Protein kinase N2 (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) Length = 842 Score = 62.8 bits (151), Expect = 3e-10 Identities = 25/48 (52%), Positives = 33/48 (68%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHRE 146 D E++K HPFF L +W AL+DK++KPPFVP + D+ N D EF E Sbjct: 770 DAEDVKKHPFFRLTDWSALLDKKVKPPFVPTIRGREDVSNFDDEFTSE 817
>sp|O00141|SGK1_HUMAN Serine/threonine-protein kinase Sgk1 (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 62.4 bits (150), Expect = 3e-10 Identities = 29/57 (50%), Positives = 38/57 (66%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPISGSFPNS 173 DF EIK+H FF+L W LI+K+I PPF P+VS ++R+ DPEF EP+ S S Sbjct: 345 DFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDPEFTEEPVPNSIGKS 401
>sp|Q8BWW9|PKN2_MOUSE Protein kinase N2 (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 62.4 bits (150), Expect = 3e-10 Identities = 25/48 (52%), Positives = 33/48 (68%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHRE 146 D E++K HPFF L +W AL+DK++KPPFVP + D+ N D EF E Sbjct: 905 DAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSE 952
>sp|Q16513|PKN2_HUMAN Protein kinase N2 (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 61.2 bits (147), Expect = 8e-10 Identities = 24/48 (50%), Positives = 33/48 (68%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHRE 146 D E++K HPFF L +W AL+DK++KPPF+P + D+ N D EF E Sbjct: 906 DAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSE 953
>sp|Q9HBY8|SGK2_HUMAN Serine/threonine-protein kinase Sgk2 (Serum/glucocorticoid regulated kinase 2) Length = 427 Score = 57.0 bits (136), Expect = 1e-08 Identities = 26/53 (49%), Positives = 36/53 (67%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPISGS 161 DF EIKNH FF+ W L K++ PPF P+V+ AD+++ DPEF +E +S S Sbjct: 342 DFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKS 394
>sp|Q96BR1|SGK3_HUMAN Serine/threonine-protein kinase Sgk3 (Serum/glucocorticoid regulated kinase 3) (Serum/glucocorticoid regulated kinase-like) Length = 496 Score = 56.2 bits (134), Expect = 2e-08 Identities = 25/50 (50%), Positives = 31/50 (62%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPI 152 DF EI+NHPFF W L+ K+I PPF P+V+ DIRN D F E + Sbjct: 409 DFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETV 458
>sp|Q9ERE3|SGK3_MOUSE Serine/threonine-protein kinase Sgk3 (Serum/glucocorticoid regulated kinase 3) (Serum/glucocorticoid regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 55.8 bits (133), Expect = 3e-08 Identities = 25/50 (50%), Positives = 31/50 (62%) Frame = +3 Query: 3 DFEEIKNHPFFALREWVALIDKQIKPPFVPHVSSNADIRNIDPEFHREPI 152 DF EI+NHPFF W L+ K+I PPF P+V+ DIRN D F E + Sbjct: 409 DFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETV 458
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,445,997 Number of Sequences: 369166 Number of extensions: 639957 Number of successful extensions: 1708 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1678 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1699 length of database: 68,354,980 effective HSP length: 99 effective length of database: 50,066,215 effective search space used: 1852449955 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)