Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02224
(726 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8R5H1|UBP15_MOUSE Ubiquitin carboxyl-terminal hydrolase... 148 2e-35
sp|Q9Y4E8|UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase... 147 2e-35
sp|P39538|UBP12_YEAST Ubiquitin carboxyl-terminal hydrolase... 144 2e-34
sp|P35123|UBP4_MOUSE Ubiquitin carboxyl-terminal hydrolase ... 142 7e-34
sp|Q13107|UBP4_HUMAN Ubiquitin carboxyl-terminal hydrolase ... 141 2e-33
sp|P51784|UBP11_HUMAN Ubiquitin carboxyl-terminal hydrolase... 135 9e-32
sp|O60079|UBP12_SCHPO Probable ubiquitin carboxyl-terminal ... 134 2e-31
sp|Q99K46|UBP11_MOUSE Ubiquitin carboxyl-terminal hydrolase... 131 2e-30
sp|O22207|UBP5_ARATH Ubiquitin carboxyl-terminal hydrolase ... 130 4e-30
sp|Q01988|UBP11_CANFA Ubiquitin carboxyl-terminal hydrolase... 125 9e-29
>sp|Q8R5H1|UBP15_MOUSE Ubiquitin carboxyl-terminal hydrolase 15 (Ubiquitin thiolesterase 15)
(Ubiquitin-specific processing protease 15)
(Deubiquitinating enzyme 15)
Length = 981
Score = 148 bits (373), Expect = 2e-35
Identities = 73/176 (41%), Positives = 104/176 (59%), Gaps = 5/176 (2%)
Frame = +1
Query: 10 SLQHQP-----LNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILH 174
S++++P + +++C+ F EKLG D WY DLW LP VL++H
Sbjct: 775 SVEYKPPKRPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVH 834
Query: 175 LKRFRSGSYRRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMG 354
LKRF Y RDK+DT+V+FP++DLD+S+F+++ + Y+L+AVSNH G
Sbjct: 835 LKRFSYSRYMRDKLDTLVDFPISDLDMSEFLINPNAGPCR---------YNLIAVSNHYG 885
Query: 355 GLGGGHYTAFAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVYVSKSQLNSTRY 522
G+GGGHYTAFAKN D WY FDDS S S + + +K AYVL Y + + T +
Sbjct: 886 GMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGF 941
>sp|Q9Y4E8|UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 (Ubiquitin thiolesterase 15)
(Ubiquitin-specific processing protease 15)
(Deubiquitinating enzyme 15) (Unph-2) (Unph4)
Length = 981
Score = 147 bits (372), Expect = 2e-35
Identities = 73/176 (41%), Positives = 103/176 (58%), Gaps = 5/176 (2%)
Frame = +1
Query: 10 SLQHQP-----LNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILH 174
S++++P + +++C+ F EKLG D WY DLW LP VL++H
Sbjct: 775 SVEYKPPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVH 834
Query: 175 LKRFRSGSYRRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMG 354
LKRF Y RDK+DT+V+FP+ DLD+S+F+++ + Y+L+AVSNH G
Sbjct: 835 LKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCR---------YNLIAVSNHYG 885
Query: 355 GLGGGHYTAFAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVYVSKSQLNSTRY 522
G+GGGHYTAFAKN D WY FDDS S S + + +K AYVL Y + + T +
Sbjct: 886 GMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGF 941
>sp|P39538|UBP12_YEAST Ubiquitin carboxyl-terminal hydrolase 12 (Ubiquitin thiolesterase 12)
(Ubiquitin-specific processing protease 12)
(Deubiquitinating enzyme 12)
Length = 1254
Score = 144 bits (364), Expect = 2e-34
Identities = 72/161 (44%), Positives = 95/161 (59%)
Frame = +1
Query: 16 QHQPLNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRFRSG 195
+ + + +++C+ F K E LG+ D WY LW P +L++HLKRF S
Sbjct: 958 KERTITLDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQ 1017
Query: 196 SYRRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGGGHY 375
DKID V FP+TDLDLS++V+ +KD D IYDL AV NH GGLGGGHY
Sbjct: 1018 RSFSDKIDATVNFPITDLDLSRYVV--YKD-DPRGL-----IYDLYAVDNHYGGLGGGHY 1069
Query: 376 TAFAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVYVSK 498
TA+ KNF DN WY FDDS + +PEN +AY+L Y+ +
Sbjct: 1070 TAYVKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFYIRR 1110
>sp|P35123|UBP4_MOUSE Ubiquitin carboxyl-terminal hydrolase 4 (Ubiquitin thiolesterase 4)
(Ubiquitin-specific processing protease 4)
(Deubiquitinating enzyme 4) (Ubiquitous nuclear protein)
Length = 962
Score = 142 bits (359), Expect = 7e-34
Identities = 74/172 (43%), Positives = 95/172 (55%)
Frame = +1
Query: 34 IENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRFRSGSYRRDK 213
+ C+ F E LG +D WY FDLW LPK+L++HLKRF Y RDK
Sbjct: 777 LRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDK 836
Query: 214 IDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGGGHYTAFAKN 393
+DTVVEFP+ L++S+FV D +YDL+AVSNH G +G GHYTA+AKN
Sbjct: 837 LDTVVEFPVRALNMSEFVCDR---------SARPYVYDLIAVSNHYGAMGVGHYTAYAKN 887
Query: 394 FIDNNWYLFDDSHTSRISPENVQTKTAYVLVYVSKSQLNSTRYSLNQCLNDD 549
++ WY FDDS S S + + TK AYVL Y + S+ SL D
Sbjct: 888 RLNGKWYYFDDSSVSLASEDQIVTKAAYVLFYQRRDDECSSTSSLGSFPGSD 939
>sp|Q13107|UBP4_HUMAN Ubiquitin carboxyl-terminal hydrolase 4 (Ubiquitin thiolesterase 4)
(Ubiquitin-specific processing protease 4)
(Deubiquitinating enzyme 4) (Ubiquitous nuclear protein
homolog)
Length = 963
Score = 141 bits (356), Expect = 2e-33
Identities = 69/152 (45%), Positives = 91/152 (59%)
Frame = +1
Query: 34 IENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRFRSGSYRRDK 213
+ +C+ F E LG +D WY FDLW LPK+L++HLKRF Y RDK
Sbjct: 778 LRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDK 837
Query: 214 IDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGGGHYTAFAKN 393
+DTVVEFP+ L++S+FV + +YDL+AVSNH G +G GHYTA+AKN
Sbjct: 838 LDTVVEFPIRGLNMSEFVC---------NLSARPYVYDLIAVSNHYGAMGVGHYTAYAKN 888
Query: 394 FIDNNWYLFDDSHTSRISPENVQTKTAYVLVY 489
++ WY FDDS+ S S + + TK AYVL Y
Sbjct: 889 KLNGKWYYFDDSNVSLASEDQIVTKAAYVLFY 920
>sp|P51784|UBP11_HUMAN Ubiquitin carboxyl-terminal hydrolase 11 (Ubiquitin thiolesterase 11)
(Ubiquitin-specific processing protease 11)
(Deubiquitinating enzyme 11)
Length = 920
Score = 135 bits (341), Expect = 9e-32
Identities = 63/161 (39%), Positives = 93/161 (57%)
Frame = +1
Query: 7 YSLQHQPLNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRF 186
Y ++ P+ ++ C+ F E L + WY DLW LP++LI+HLKRF
Sbjct: 729 YVMKKAPVRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRF 788
Query: 187 RSGSYRRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGG 366
+ R+K+DT+VEFP+ DLD S+FV+ +S+ ++ YDL+AVSNH GG+
Sbjct: 789 SYTKFSREKLDTLVEFPIRDLDFSEFVIQPQNESNPELYK-----YDLIAVSNHYGGMRD 843
Query: 367 GHYTAFAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVY 489
GHYT FA N W+ FDD+ S ++ +++K AYVL Y
Sbjct: 844 GHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFY 884
>sp|O60079|UBP12_SCHPO Probable ubiquitin carboxyl-terminal hydrolase 12 (Ubiquitin
thiolesterase 12) (Ubiquitin-specific processing protease
12) (Deubiquitinating enzyme 12)
Length = 979
Score = 134 bits (338), Expect = 2e-31
Identities = 70/158 (44%), Positives = 96/158 (60%)
Frame = +1
Query: 28 LNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRFRSGSYRR 207
+ + +C++EF KTE+LG D WY ++W+ P++LI HLKRF S R
Sbjct: 825 ITLNDCLDEFEKTEQLGEEDPWYCPTCKEFRQASKQMEIWRCPEILIFHLKRFSSERRFR 884
Query: 208 DKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGGGHYTAFA 387
DKID +VEFP+ +LD+S ++K S+ +N IY+L AV NH GGLGGGHYTAFA
Sbjct: 885 DKIDDLVEFPIDNLDMSMRT-GSYKLSEK---ENPKLIYELYAVDNHYGGLGGGHYTAFA 940
Query: 388 KNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVYVSKS 501
KN + +Y FDDS + + PE T AY+L Y K+
Sbjct: 941 KNPDNGQFYCFDDSRVTPVCPEETVTSAAYLLFYRRKT 978
>sp|Q99K46|UBP11_MOUSE Ubiquitin carboxyl-terminal hydrolase 11 (Ubiquitin thiolesterase 11)
(Ubiquitin-specific processing protease 11)
(Deubiquitinating enzyme 11)
Length = 797
Score = 131 bits (330), Expect = 2e-30
Identities = 63/161 (39%), Positives = 90/161 (55%)
Frame = +1
Query: 7 YSLQHQPLNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRF 186
Y L+ P+ ++ C+ F E L + WY DLW LP+VLI+HLKRF
Sbjct: 607 YMLKKSPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRF 666
Query: 187 RSGSYRRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGG 366
R+K+DT+V+FP+ DLD S+FV+ +S ++ YDL+AVSNH GG+
Sbjct: 667 SFSKISREKLDTLVQFPIRDLDFSEFVIKPKNESSPDLYK-----YDLIAVSNHYGGMRD 721
Query: 367 GHYTAFAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVY 489
GHYT FA N W+ DD+ S ++ +++K AYVL Y
Sbjct: 722 GHYTTFACNKDSGQWHYLDDNSVSPVNENQIESKAAYVLFY 762
>sp|O22207|UBP5_ARATH Ubiquitin carboxyl-terminal hydrolase 5 (Ubiquitin thiolesterase 5)
(Ubiquitin-specific processing protease 5)
(Deubiquitinating enzyme 5) (AtUBP5)
Length = 924
Score = 130 bits (327), Expect = 4e-30
Identities = 62/160 (38%), Positives = 97/160 (60%)
Frame = +1
Query: 22 QPLNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRFRSGSY 201
+PL++ C+ F++ E L +++W+ DLW+LP+VL++HLKRF
Sbjct: 766 EPLSLYACLEAFLREEPLVPDEMWFCPQCNERRQASKKLDLWRLPEVLVIHLKRFSYSRS 825
Query: 202 RRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGGGHYTA 381
+ K++T V FP+ DLDL+K+V + + + ++Y+L A++NH GG+G GHYTA
Sbjct: 826 MKHKLETFVNFPIHDLDLTKYVANKNL--------SQPQLYELYALTNHYGGMGSGHYTA 877
Query: 382 FAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVYVSKS 501
K D+ WY FDDSH S I+ ++V++ AYVL Y KS
Sbjct: 878 HIKLLDDSRWYNFDDSHISHINEDDVKSGAAYVLFYRRKS 917
>sp|Q01988|UBP11_CANFA Ubiquitin carboxyl-terminal hydrolase 11 (Ubiquitin thiolesterase
11) (Ubiquitin-specific processing protease 11)
(Deubiquitinating enzyme 11)
Length = 445
Score = 125 bits (315), Expect = 9e-29
Identities = 63/161 (39%), Positives = 89/161 (55%)
Frame = +1
Query: 7 YSLQHQPLNIENCVNEFIKTEKLGINDLWYXXXXXXXXXXXXXFDLWQLPKVLILHLKRF 186
Y L+ P+ ++ C+ F E L + W+ DLW LP+ LI+HLKRF
Sbjct: 254 YVLKKAPVRLQECIELFTTVETLEKENPWFCPTCKQHQLATKKLDLWMLPETLIIHLKRF 313
Query: 187 RSGSYRRDKIDTVVEFPLTDLDLSKFVLDAHKDSDDHSFQNDDEIYDLVAVSNHMGGLGG 366
+ R+K+DT+VEFP+ DLD S+FV+ +S ++ YDL+AVSNH GGL
Sbjct: 314 SYTKFSREKLDTLVEFPIRDLDFSEFVIKPQNESAPELYK-----YDLIAVSNHYGGLRD 368
Query: 367 GHYTAFAKNFIDNNWYLFDDSHTSRISPENVQTKTAYVLVY 489
GHYT FA N FDD+ S ++ +++K AYVL Y
Sbjct: 369 GHYTTFACNKDSGQSDYFDDNSVSPVTENQIESKAAYVLFY 409
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,710,513
Number of Sequences: 369166
Number of extensions: 1609558
Number of successful extensions: 4367
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4168
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4292
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6510836890
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)