Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02218
(751 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransfera... 285 7e-77
sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransfera... 283 3e-76
sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransfera... 281 1e-75
sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransfera... 281 1e-75
sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransfera... 279 7e-75
sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransfera... 278 9e-75
sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferas... 274 2e-73
sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoylt... 253 4e-67
sp|Q75EK2|NMT_ASHGO Glycylpeptide N-tetradecanoyltransferas... 216 5e-56
sp|O74234|NMT_CANGA Glycylpeptide N-tetradecanoyltransferas... 216 7e-56
>sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 529
Score = 285 bits (730), Expect = 7e-77
Identities = 137/192 (71%), Positives = 155/192 (80%)
Frame = +1
Query: 148 AVKTKYEFWDTQPVLKLDEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQL 327
A K +Y+FWDTQPV KL+EV + IEP+KD IR E YSLP GF WD + L N L
Sbjct: 145 ATKRRYQFWDTQPVPKLNEVITSHGAIEPDKD--NIRQEPYSLPQGFMWDTLDLSNAEVL 202
Query: 328 AELYTLLNENYVEDDDNMFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAV 507
ELYTLLNENYVEDDDNMFRFDYSP FL WAL+ PGW +W+ G+RV SNKKLVGFISA+
Sbjct: 203 KELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAI 262
Query: 508 PGTVKVYEKSVRMVEINFLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPK 687
P +++Y+ RMVEINFLCVHKKLRSKRVAPVLIREITRRVN +GIFQAVYT GV+LPK
Sbjct: 263 PANIRIYDSVKRMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPK 322
Query: 688 PVATCMYWHRSV 723
PVATC YWHRS+
Sbjct: 323 PVATCRYWHRSL 334
>sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 498
Score = 283 bits (724), Expect = 3e-76
Identities = 134/192 (69%), Positives = 155/192 (80%)
Frame = +1
Query: 148 AVKTKYEFWDTQPVLKLDEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQL 327
A K +Y+FWDTQPV KLDEV + IEP+KD +R E YSLP GF WD + L + L
Sbjct: 114 AAKHRYQFWDTQPVPKLDEVITSHGAIEPDKD--NVRQEPYSLPQGFMWDTLDLSDAEVL 171
Query: 328 AELYTLLNENYVEDDDNMFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAV 507
ELYTLLNENYVEDDDNMFRFDYSP FL WAL+ PGW +W+ G+RV SNKKLVGFISA+
Sbjct: 172 KELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAI 231
Query: 508 PGTVKVYEKSVRMVEINFLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPK 687
P +++Y+ +MVEINFLCVHKKLRSKRVAPVLIREITRRVN +GIFQAVYT GV+LPK
Sbjct: 232 PANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPK 291
Query: 688 PVATCMYWHRSV 723
P+ATC YWHRS+
Sbjct: 292 PIATCRYWHRSL 303
>sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 496
Score = 281 bits (719), Expect = 1e-75
Identities = 140/235 (59%), Positives = 169/235 (71%), Gaps = 1/235 (0%)
Frame = +1
Query: 22 SEDNHNHDQCNSDGDMPAE-ISLMDEIKKLNLIPSNKLAKNKSAVKTKYEFWDTQPVLKL 198
SE + DQ +PAE I + + +L + + A K Y+FWDTQPV KL
Sbjct: 69 SETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKL 128
Query: 199 DEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQLAELYTLLNENYVEDDDN 378
EV + P+EP+KD IR E Y+LP GF WD + L + L ELYTLLNENYVEDDDN
Sbjct: 129 GEVVNTHGPVEPDKD--NIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDN 186
Query: 379 MFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAVPGTVKVYEKSVRMVEIN 558
MFRFDYSP FL WAL+ PGW P+W+ G+RV S++KLVGFISA+P + +Y+ +MVEIN
Sbjct: 187 MFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEIN 246
Query: 559 FLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPKPVATCMYWHRSV 723
FLCVHKKLRSKRVAPVLIREITRRV+ +GIFQAVYT GV+LPKPV TC YWHRS+
Sbjct: 247 FLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSL 301
>sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 497
Score = 281 bits (719), Expect = 1e-75
Identities = 140/235 (59%), Positives = 169/235 (71%), Gaps = 1/235 (0%)
Frame = +1
Query: 22 SEDNHNHDQCNSDGDMPAE-ISLMDEIKKLNLIPSNKLAKNKSAVKTKYEFWDTQPVLKL 198
SE + DQ +PAE I + + +L + + A K Y+FWDTQPV KL
Sbjct: 69 SETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKL 128
Query: 199 DEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQLAELYTLLNENYVEDDDN 378
EV + P+EP+KD IR E Y+LP GF WD + L + L ELYTLLNENYVEDDDN
Sbjct: 129 GEVVNTHGPVEPDKD--NIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDN 186
Query: 379 MFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAVPGTVKVYEKSVRMVEIN 558
MFRFDYSP FL WAL+ PGW P+W+ G+RV S++KLVGFISA+P + +Y+ +MVEIN
Sbjct: 187 MFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEIN 246
Query: 559 FLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPKPVATCMYWHRSV 723
FLCVHKKLRSKRVAPVLIREITRRV+ +GIFQAVYT GV+LPKPV TC YWHRS+
Sbjct: 247 FLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSL 301
>sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 496
Score = 279 bits (713), Expect = 7e-75
Identities = 139/235 (59%), Positives = 168/235 (71%), Gaps = 1/235 (0%)
Frame = +1
Query: 22 SEDNHNHDQCNSDGDMPAE-ISLMDEIKKLNLIPSNKLAKNKSAVKTKYEFWDTQPVLKL 198
S+ DQ +PAE I + + +L + + A K Y+FWDTQPV KL
Sbjct: 69 SDMESTQDQPVKMTSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKL 128
Query: 199 DEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQLAELYTLLNENYVEDDDN 378
EV + P+EP+KD IR E Y+LP GF WD + L + L ELYTLLNENYVEDDDN
Sbjct: 129 GEVVNTHGPVEPDKD--NIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDN 186
Query: 379 MFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAVPGTVKVYEKSVRMVEIN 558
MFRFDYSP FL WAL+ PGW P+W+ G+RV S++KLVGFISA+P + +Y+ +MVEIN
Sbjct: 187 MFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEIN 246
Query: 559 FLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPKPVATCMYWHRSV 723
FLCVHKKLRSKRVAPVLIREITRRV+ +GIFQAVYT GV+LPKPV TC YWHRS+
Sbjct: 247 FLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSL 301
>sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 498
Score = 278 bits (712), Expect = 9e-75
Identities = 133/192 (69%), Positives = 154/192 (80%)
Frame = +1
Query: 148 AVKTKYEFWDTQPVLKLDEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQL 327
A K +Y+FWDTQPV KL+EV + IE +K+ +R E YSLP GF WD + L N L
Sbjct: 114 AAKHRYQFWDTQPVPKLNEVITSHGAIEADKE--NVRQEPYSLPQGFMWDTLDLGNAEVL 171
Query: 328 AELYTLLNENYVEDDDNMFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAV 507
ELYTLLNENYVEDDDNMFRFDYSP FL WAL+ PGW +W+ G+RV SNKKLVGFISA+
Sbjct: 172 RELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLLQWHCGVRVSSNKKLVGFISAI 231
Query: 508 PGTVKVYEKSVRMVEINFLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPK 687
P +++Y+ +MVEINFLCVHKKLRSKRVAPVLIREITRRVN +GIFQAVYT GV+LPK
Sbjct: 232 PANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREITRRVNLEGIFQAVYTAGVVLPK 291
Query: 688 PVATCMYWHRSV 723
PVATC YWHRS+
Sbjct: 292 PVATCRYWHRSL 303
>sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT) (dNMT)
Length = 472
Score = 274 bits (701), Expect = 2e-73
Identities = 137/230 (59%), Positives = 166/230 (72%), Gaps = 6/230 (2%)
Frame = +1
Query: 52 NSDGDMP------AEISLMDEIKKLNLIPSNKLAKNKSAVKTKYEFWDTQPVLKLDEVTE 213
N D + P A +S + L S+ +A + K K+ FW TQPV KLDE
Sbjct: 49 NEDAEQPDGAKNEASVSANASKQALLQAVSDAMASTRQMAK-KFAFWSTQPVTKLDEQVT 107
Query: 214 LNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQLAELYTLLNENYVEDDDNMFRFD 393
NE IEPNK+ISEIR+ Y+LP GF W + L++ + L ELYTLLNENYVEDDD MFRFD
Sbjct: 108 TNECIEPNKEISEIRALPYTLPGGFKWVTLDLNDANDLKELYTLLNENYVEDDDAMFRFD 167
Query: 394 YSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAVPGTVKVYEKSVRMVEINFLCVH 573
Y P FLKW+LQ PGW+ +W+ G+RV + KLVGFISA+P +K Y+K +++V+INFLCVH
Sbjct: 168 YQPEFLKWSLQPPGWKRDWHVGVRVEKSGKLVGFISAIPSKLKSYDKVLKVVDINFLCVH 227
Query: 574 KKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPKPVATCMYWHRSV 723
KKLRSKRVAPVLIREITRRVN GIFQA YT GV+LP PVATC YWHRS+
Sbjct: 228 KKLRSKRVAPVLIREITRRVNLTGIFQAAYTAGVVLPTPVATCRYWHRSL 277
>sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 450
Score = 253 bits (646), Expect = 4e-67
Identities = 119/189 (62%), Positives = 149/189 (78%), Gaps = 2/189 (1%)
Frame = +1
Query: 163 YEFWDTQPVLKLDEVT--ELNEPIEPNKDISEIRSESYSLPAGFYWDDVCLDNEHQLAEL 336
++FW TQPV ++DE ++N IE N + ++R+E +SLPAGF W +V L +E QL EL
Sbjct: 66 FQFWSTQPVPQMDETVPADVNCAIEENIALDKVRAEPFSLPAGFRWSNVDLSDEEQLNEL 125
Query: 337 YTLLNENYVEDDDNMFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKKLVGFISAVPGT 516
Y LL NYVEDDD+MFRFDYS FLKWALQ PG+RPEW+ G+R SN +L+ FI AVP T
Sbjct: 126 YNLLTRNYVEDDDSMFRFDYSADFLKWALQVPGFRPEWHCGVRADSNNRLLAFIGAVPQT 185
Query: 517 VKVYEKSVRMVEINFLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVYTGGVLLPKPVA 696
V+VY+K+V MVEINFLCVHK LRS+RVAPVLIREITRRVN GIFQA +T G+++PKPV+
Sbjct: 186 VRVYDKTVNMVEINFLCVHKNLRSRRVAPVLIREITRRVNVTGIFQAAFTAGIVIPKPVS 245
Query: 697 TCMYWHRSV 723
C Y+HRS+
Sbjct: 246 VCRYYHRSL 254
>sp|Q75EK2|NMT_ASHGO Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 452
Score = 216 bits (550), Expect = 5e-56
Identities = 100/208 (48%), Positives = 141/208 (67%)
Frame = +1
Query: 94 EIKKLNLIPSNKLAKNKSAVKTKYEFWDTQPVLKLDEVTELNEPIEPNKDISEIRSESYS 273
E+ LN +KL + + +Y+FW TQPV + DE E PI P + + ++R E Y
Sbjct: 15 EMLALNSGDMSKLTQQQRKAFEEYKFWKTQPVARFDEKVEEEGPINPPRRVEDVRDEPYP 74
Query: 274 LPAGFYWDDVCLDNEHQLAELYTLLNENYVEDDDNMFRFDYSPLFLKWALQAPGWRPEWY 453
L F W + + L +++ LLNENY+ED D+ FRF+Y+ F WAL+ PGWR EW+
Sbjct: 75 LLEEFEWRTMDITTGQDLEDVFVLLNENYIEDKDSTFRFNYTREFFNWALKPPGWRKEWH 134
Query: 454 AGIRVCSNKKLVGFISAVPGTVKVYEKSVRMVEINFLCVHKKLRSKRVAPVLIREITRRV 633
G+RV + +LV FISAVP T++V + ++ VEINFLC+HKKLRSKR+AP+LI+EITRRV
Sbjct: 135 VGVRVRQSGRLVAFISAVPTTLEVRGREMKSVEINFLCIHKKLRSKRLAPILIKEITRRV 194
Query: 634 NKQGIFQAVYTGGVLLPKPVATCMYWHR 717
NK I+ A+Y+ G++LP P++TC Y HR
Sbjct: 195 NKCDIWHALYSAGIVLPSPISTCRYTHR 222
>sp|O74234|NMT_CANGA Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 451
Score = 216 bits (549), Expect = 7e-56
Identities = 103/198 (52%), Positives = 138/198 (69%)
Frame = +1
Query: 124 NKLAKNKSAVKTKYEFWDTQPVLKLDEVTELNEPIEPNKDISEIRSESYSLPAGFYWDDV 303
+KL N+ +Y+FW TQPV K DE + PI K ++I E L F W +
Sbjct: 21 SKLTANQRKEMKEYKFWKTQPVTKFDEEVKEEGPIHEEKTPADIPDEPLPLLPDFEWCAI 80
Query: 304 CLDNEHQLAELYTLLNENYVEDDDNMFRFDYSPLFLKWALQAPGWRPEWYAGIRVCSNKK 483
+D+E QL +++ LLNENYVED D FRF+Y+ F WAL++PGW P+W+ G+RV ++KK
Sbjct: 81 DVDDEKQLEDVFVLLNENYVEDRDASFRFNYTREFFNWALKSPGWTPDWHIGVRVKASKK 140
Query: 484 LVGFISAVPGTVKVYEKSVRMVEINFLCVHKKLRSKRVAPVLIREITRRVNKQGIFQAVY 663
L+ FISA+P ++V K + VEINFLCVHK+LRSKR+ PVLI+EITRRVNK+ I+ A+Y
Sbjct: 141 LIAFISAIPVRLRVRAKVIDSVEINFLCVHKQLRSKRLTPVLIKEITRRVNKRNIWHALY 200
Query: 664 TGGVLLPKPVATCMYWHR 717
T GV+LP PV+TC Y HR
Sbjct: 201 TAGVVLPAPVSTCRYAHR 218
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,150,094
Number of Sequences: 369166
Number of extensions: 1772744
Number of successful extensions: 4898
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4749
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4885
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6824907600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)