Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02178
(746 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O80765|PANK1_ARATH Pantothenate kinase 1 (Pantothenic ac... 50 5e-06
sp|Q9NVE7|PANK4_HUMAN Pantothenate kinase 4 (Pantothenic ac... 45 3e-04
sp|Q923S8|PANK4_RAT Pantothenate kinase 4 (Pantothenic acid... 44 5e-04
sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2 (Pantothenic ac... 44 6e-04
sp|Q8K4K6|PANK1_MOUSE Pantothenate kinase 1 (Pantothenic ac... 35 0.21
sp|Q8R2W9|PANK3_MOUSE Pantothenate kinase 3 (Pantothenic ac... 35 0.28
sp|Q9H999|PANK3_HUMAN Pantothenate kinase 3 (Pantothenic ac... 35 0.28
sp|O28543|YH31_ARCFU Hypothetical protein AF1731 34 0.36
sp|Q8TE04|PANK1_HUMAN Pantothenate kinase 1 (Pantothenic ac... 34 0.48
sp|Q9BZ23|PANK2_HUMAN Pantothenate kinase 2, mitochondrial ... 32 1.8
>sp|O80765|PANK1_ARATH Pantothenate kinase 1 (Pantothenic acid kinase 1) (AtCoaA)
Length = 383
Score = 50.4 bits (119), Expect = 5e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 12/215 (5%)
Frame = +3
Query: 63 LDRGCSLTKIIYVD-NEDSANLDKNSTSNVI-ILTVALFPNSKFEDALIWLKEKAVFPEN 236
LD G +L K++Y N D + +N S V L A F K +D L +++ +
Sbjct: 11 LDIGGTLIKLVYFSANGDYSEESRNGCSVVKGRLCFAKFETRKIDDCLEFIRFNILHHSG 70
Query: 237 KELP---------FHLTGAGGVKYSEKIKEILQRDVVFIDEFMSQSRGAYYLLRDVPLKE 389
+ P TG G K+++ KE L DE S G +LL+ VP +
Sbjct: 71 VQQPNGEGHDKLYVKATGGGAFKFADLFKEKLGILFDKEDEMCSLVGGVNFLLKTVpreA 130
Query: 390 VVYPDIESDCDGWFDIPFITDVKVQFEEMVGKRKEIK-STEDLFPCIFGFMGSGGGLVYI 566
Y D G++K ++ DL+P + +GSG ++ +
Sbjct: 131 FTYLD-------------------------GQKKFVEIDHNDLYPYLLVNIGSGVSMIKV 165
Query: 567 GSEGTFRMVSGLPASGKSFIGICRCILGTNDYMKL 671
+G + +SG G +F+G+ + + + +L
Sbjct: 166 DGDGKYERISGTSLGGGTFLGLGKLLTKCKSFDEL 200
>sp|Q9NVE7|PANK4_HUMAN Pantothenate kinase 4 (Pantothenic acid kinase 4) (hPanK4)
Length = 773
Score = 44.7 bits (104), Expect = 3e-04
Identities = 41/167 (24%), Positives = 72/167 (43%)
Frame = +3
Query: 171 FPNSKFEDALIWLKEKAVFPENKELPFHLTGAGGVKYSEKIKEILQRDVVFIDEFMSQSR 350
F N+ E L ++K+ V E K + TG G K+ + I+E L+ V D +
Sbjct: 96 FENTYIEACLDFIKDHLVNTETKVI--QATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIK 153
Query: 351 GAYYLLRDVPLKEVVYPDIESDCDGWFDIPFITDVKVQFEEMVGKRKEIKSTEDLFPCIF 530
G ++L+++P + VY + D D F +F+ + +FP +
Sbjct: 154 GCNFVLKNIPHEAFVY---QKDSDPEF----------RFQT---------NHPHIFPYLL 191
Query: 531 GFMGSGGGLVYIGSEGTFRMVSGLPASGKSFIGICRCILGTNDYMKL 671
+GSG +V + +E F V G G +F G+ + T + +L
Sbjct: 192 VNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDEL 238
Score = 31.2 bits (69), Expect = 3.1
Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = +2
Query: 623 YWNL-SMYSWNKRLHEIMAMAARGDRRNVDTQIKDVLG 733
+W L ++ + K+ E++ +A+RG NVD ++DV G
Sbjct: 222 FWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYG 259
>sp|Q923S8|PANK4_RAT Pantothenate kinase 4 (Pantothenic acid kinase 4) (rPanK4)
Length = 773
Score = 43.9 bits (102), Expect = 5e-04
Identities = 39/169 (23%), Positives = 74/169 (43%)
Frame = +3
Query: 171 FPNSKFEDALIWLKEKAVFPENKELPFHLTGAGGVKYSEKIKEILQRDVVFIDEFMSQSR 350
F N+ E L ++++ V E K + TG G K+ + I+E L+ V D +
Sbjct: 96 FENTYMEACLDFIRDHLVNTETKVI--QATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIK 153
Query: 351 GAYYLLRDVPLKEVVYPDIESDCDGWFDIPFITDVKVQFEEMVGKRKEIKSTEDLFPCIF 530
G ++L+++P + +Y + D D F +F+ + ++FP +
Sbjct: 154 GCNFVLKNIPHEAFMY---QKDSDPEF----------RFQT---------NHPNIFPYLL 191
Query: 531 GFMGSGGGLVYIGSEGTFRMVSGLPASGKSFIGICRCILGTNDYMKLWQ 677
+GSG +V + +E F + G G +F G+ + T + +L Q
Sbjct: 192 VNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQ 240
Score = 30.0 bits (66), Expect = 6.9
Identities = 12/38 (31%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Frame = +2
Query: 623 YWNL-SMYSWNKRLHEIMAMAARGDRRNVDTQIKDVLG 733
+W L ++ + K+ E++ +A+RG NVD ++D+ G
Sbjct: 222 FWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYG 259
>sp|Q8L5Y9|PANK2_ARATH Pantothenate kinase 2 (Pantothenic acid kinase 2)
Length = 870
Score = 43.5 bits (101), Expect = 6e-04
Identities = 50/239 (20%), Positives = 90/239 (37%), Gaps = 31/239 (12%)
Frame = +3
Query: 63 LDRGCSLTKIIYVDNEDSANLDKNSTSNVIILTVAL-------------------FPNSK 185
LD G SL K++Y + + D + I + + F K
Sbjct: 51 LDIGGSLIKLLYFSRHEDYSNDDDKRKRTIKERLGITNGNLRSYPVLGGRLHFVKFETHK 110
Query: 186 FEDALIWLKEKAV-----FP-ENKELPF-----HLTGAGGVKYSEKIKEILQRDVVFIDE 332
+ L ++ K + +P +K LP +TG G K+++ KE L + DE
Sbjct: 111 INECLDFIHSKQLHRRDPYPWSSKTLPLGTGVIKVTGGGAFKFADLFKERLGVSIEKEDE 170
Query: 333 FMSQSRGAYYLLRDVPLKEVVYPDIESDCDGWFDIPFITDVKVQFEEMVGKRKEIK-STE 509
GA +LL+ + + F M G+++ ++
Sbjct: 171 MHCLVSGANFLLKAIRHEA-------------------------FTHMEGEKEFVQIDPN 205
Query: 510 DLFPCIFGFMGSGGGLVYIGSEGTFRMVSGLPASGKSFIGICRCILGTNDYMKLWQWQQ 686
DL+P + +GSG ++ + EG F VSG G ++ G+ R + + +L + Q
Sbjct: 206 DLYPYLLVNVGSGVSIIKVDGEGKFERVSGTNVGGGTYWGLGRLLTKCKSFDELLELSQ 264
>sp|Q8K4K6|PANK1_MOUSE Pantothenate kinase 1 (Pantothenic acid kinase 1) (mPank1) (mPank)
Length = 548
Score = 35.0 bits (79), Expect = 0.21
Identities = 46/234 (19%), Positives = 93/234 (39%), Gaps = 33/234 (14%)
Frame = +3
Query: 60 GLDRGCSLTKIIYVDNED-SANLDKNSTSNVIILTVALFPNSKF-----EDALIWLKEKA 221
G+D G +L K++Y + +D +A ++ N+ + L N+ + D + LK
Sbjct: 190 GMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLT 249
Query: 222 VFPENKELPF--------HL-------------------TGAGGVKYSEKIKEILQRDVV 320
+ L F HL TG G K+ E + I +
Sbjct: 250 MCGRKGNLHFIRFPTCAMHLFIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLH 309
Query: 321 FIDEFMSQSRGAYYLLRDVPLKEVVYPDIESDCDGWFDIPFITDVKVQFEEMVGKRKEIK 500
+DE +G Y+ + V + + +C +F+ P ++ +K+
Sbjct: 310 KLDELDCLIQGLLYV-------DSVGFNGKPECY-YFENPTNPELC---------QKKPY 352
Query: 501 STEDLFPCIFGFMGSGGGLVYIGSEGTFRMVSGLPASGKSFIGICRCILGTNDY 662
++ +P + MGSG ++ + S+ ++ V+G G +F+G+C + G +
Sbjct: 353 CLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETF 406
Score = 31.2 bits (69), Expect = 3.1
Identities = 13/25 (52%), Positives = 17/25 (68%)
Frame = +2
Query: 665 EIMAMAARGDRRNVDTQIKDVLGDD 739
E + MAA+GD NVD +KD+ G D
Sbjct: 408 EALDMAAKGDSTNVDKLVKDIYGGD 432
>sp|Q8R2W9|PANK3_MOUSE Pantothenate kinase 3 (Pantothenic acid kinase 3) (mPanK3)
Length = 370
Score = 34.7 bits (78), Expect = 0.28
Identities = 13/52 (25%), Positives = 29/52 (55%)
Frame = +3
Query: 507 EDLFPCIFGFMGSGGGLVYIGSEGTFRMVSGLPASGKSFIGICRCILGTNDY 662
+D +P + +GSG ++ + S+ ++ V+G G +F+G+C + G +
Sbjct: 180 DDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESF 231
>sp|Q9H999|PANK3_HUMAN Pantothenate kinase 3 (Pantothenic acid kinase 3) (hPanK3)
Length = 370
Score = 34.7 bits (78), Expect = 0.28
Identities = 13/52 (25%), Positives = 29/52 (55%)
Frame = +3
Query: 507 EDLFPCIFGFMGSGGGLVYIGSEGTFRMVSGLPASGKSFIGICRCILGTNDY 662
+D +P + +GSG ++ + S+ ++ V+G G +F+G+C + G +
Sbjct: 180 DDPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESF 231
>sp|O28543|YH31_ARCFU Hypothetical protein AF1731
Length = 103
Score = 34.3 bits (77), Expect = 0.36
Identities = 26/66 (39%), Positives = 36/66 (54%)
Frame = +3
Query: 156 LTVALFPNSKFEDALIWLKEKAVFPENKELPFHLTGAGGVKYSEKIKEILQRDVVFIDEF 335
LTV P SK D LI L+EK E + L T G + +++KEILQR + ++EF
Sbjct: 36 LTVDGLPESKVRD-LIELREKYQLDELEFLFIVGTAVGLYQGQKQVKEILQRRMSALNEF 94
Query: 336 MSQSRG 353
+S G
Sbjct: 95 VSSLVG 100
>sp|Q8TE04|PANK1_HUMAN Pantothenate kinase 1 (Pantothenic acid kinase 1) (hPanK1) (hPanK)
Length = 598
Score = 33.9 bits (76), Expect = 0.48
Identities = 28/135 (20%), Positives = 60/135 (44%)
Frame = +3
Query: 258 TGAGGVKYSEKIKEILQRDVVFIDEFMSQSRGAYYLLRDVPLKEVVYPDIESDCDGWFDI 437
TG G K+ E + I + +DE +G Y+ + V + + +C +F+
Sbjct: 339 TGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYV-------DSVGFNGKPECY-YFEN 390
Query: 438 PFITDVKVQFEEMVGKRKEIKSTEDLFPCIFGFMGSGGGLVYIGSEGTFRMVSGLPASGK 617
P ++ +K+ ++ +P + MGSG ++ + S+ ++ V+G G
Sbjct: 391 PTNPELC---------QKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGG 441
Query: 618 SFIGICRCILGTNDY 662
+F+G+C + G +
Sbjct: 442 TFLGLCCLLTGCETF 456
Score = 31.6 bits (70), Expect = 2.4
Identities = 13/25 (52%), Positives = 17/25 (68%)
Frame = +2
Query: 665 EIMAMAARGDRRNVDTQIKDVLGDD 739
E + MAA+GD NVD +KD+ G D
Sbjct: 458 EALEMAAKGDSTNVDKLVKDIYGGD 482
>sp|Q9BZ23|PANK2_HUMAN Pantothenate kinase 2, mitochondrial precursor (Pantothenic acid
kinase 2) (hPANK2)
Length = 570
Score = 32.0 bits (71), Expect = 1.8
Identities = 31/141 (21%), Positives = 53/141 (37%), Gaps = 3/141 (2%)
Frame = +3
Query: 249 FHLTGAGGVKYSEKIKEILQRDVVFIDEFMSQSRGAYYLLRDVPLKEVVYPDIESDCDGW 428
F TG G K+ + I + +DE +G Y+ + V + S C
Sbjct: 311 FCATGGGAYKFEQDFLTIGDLQLCKLDELDCLIKGILYI-------DSVGFNGRSQC--- 360
Query: 429 FDIPFITDVKVQFEEMVGKRKEIKSTEDL---FPCIFGFMGSGGGLVYIGSEGTFRMVSG 599
FE K K DL +P + +GSG ++ + S+ ++ V+G
Sbjct: 361 ----------YYFENPADSEKCQKLPFDLKNPYPLLLVNIGSGVSILAVYSKDNYKRVTG 410
Query: 600 LPASGKSFIGICRCILGTNDY 662
G +F G+C + G +
Sbjct: 411 TSLGGGTFFGLCCLLTGCTTF 431
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,092,097
Number of Sequences: 369166
Number of extensions: 1858023
Number of successful extensions: 5011
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4872
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5007
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)