Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02177
(759 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P04146|COPIA_DROME Copia protein (Gag-int-pol protein) [... 35 0.22
sp|Q9R0X5|RPGR_MOUSE X-linked retinitis pigmentosa GTPase r... 35 0.22
sp|P18160|KYK1_DICDI Non-receptor tyrosine kinase spore lys... 34 0.37
sp|P54675|PI3K3_DICDI Phosphatidylinositol 3-kinase 3 (PI3-... 33 0.64
sp|P40872|PKSM_BACSU Putative polyketide synthase pksM 33 0.64
sp|P57458|IF2_BUCAI Translation initiation factor IF-2 32 1.4
sp|O75400|FNBP3_HUMAN Formin-binding protein 3 (Huntingtin ... 32 1.9
sp|Q8N0V4|LGI2_HUMAN Leucine-rich repeat LGI family member ... 32 2.4
sp|P54673|PI3K1_DICDI Phosphatidylinositol 3-kinase 1 (PI3-... 32 2.4
sp|Q06366|BXEN_CLOBU Botulinum neurotoxin type E, nontoxic ... 32 2.4
>sp|P04146|COPIA_DROME Copia protein (Gag-int-pol protein) [Contains: Copia VLP protein;
Copia protease ]
Length = 1409
Score = 35.0 bits (79), Expect = 0.22
Identities = 46/151 (30%), Positives = 64/151 (42%), Gaps = 29/151 (19%)
Frame = +1
Query: 199 NVEKIK-SIRIENKNFLNDSLIIP----------------LGDSGDSNRNFTRKRNRNIG 327
N++ +K S ENKNF NDS I L DS +SN+ F N
Sbjct: 753 NIQFLKDSKESENKNFPNDSRKIIQTEFPNESKECDNIQFLKDSKESNKYFL-----NES 807
Query: 328 KQRFRVSSLGESSTSGKNNHQAE-----------LNSTRSFQNYKRHNKESALFKNKFPQ 474
K+R R L ES SG N E +++ + N+ S K K PQ
Sbjct: 808 KKRKRDDHLNESKGSGNPNESRESETAEHLKEIGIDNPTKNDGIEIINRRSERLKTK-PQ 866
Query: 475 ENWKDEKDESMLDQVLEATKIF-DIDNNKQE 564
++ +E+D S+ VL A IF D+ N+ E
Sbjct: 867 ISY-NEEDNSLNKVVLNAHTIFNDVPNSFDE 896
>sp|Q9R0X5|RPGR_MOUSE X-linked retinitis pigmentosa GTPase regulator (mRpgr)
Length = 1001
Score = 35.0 bits (79), Expect = 0.22
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 5/132 (3%)
Frame = +1
Query: 193 LVNVEKIKSIRIENKNFLNDSLIIPLGDSGDSNRNFTRKRNRNIGKQRFRVSSLGESSTS 372
++ V +K IR +N +DSL D D N + N++I ++R S ++ T
Sbjct: 624 VMEVADVKKIRESEENSKSDSLF---DDLPDKTMNSESEDNKDIAEER---RSSEQNMTF 677
Query: 373 GKNNHQAELNSTRSFQNYKRHNKESALFKNKFPQ-----ENWKDEKDESMLDQVLEATKI 537
E S+ +RHN++ + + + P+ KDEKDE D+V
Sbjct: 678 DSETELVE--EPDSYMECERHNEQDSAEELEQPKLVEYSSEEKDEKDEKDDDEVETENLW 735
Query: 538 FDIDNNKQENRS 573
+D + +QE +
Sbjct: 736 YDRNCTEQETEN 747
>sp|P18160|KYK1_DICDI Non-receptor tyrosine kinase spore lysis A (Tyrosine-protein kinase
1)
Length = 1584
Score = 34.3 bits (77), Expect = 0.37
Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 1/146 (0%)
Frame = +1
Query: 208 KIKSIRIENKNFLNDSLIIPLGDSGDSNRNFTRKRNRN-IGKQRFRVSSLGESSTSGKNN 384
K + + KN + S+++P G++ +++ N N N IG + ++ +S S NN
Sbjct: 383 KFSQVTLMLKNVNSTSILVPNGNNNNNSNNNNNNNNNNIIGNGKITTTTTTSTSPSSINN 442
Query: 385 HQAELNSTRSFQNYKRHNKESALFKNKFPQENWKDEKDESMLDQVLEATKIFDIDNNKQE 564
++ +++S + N +N + N N + S T +I+N
Sbjct: 443 NE-DISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNS------SNTNNNNINNTTNN 495
Query: 565 NRSGMGKYEPDKFYDCLSGKGNHPVS 642
N S + + S N+ ++
Sbjct: 496 NNSNSNNNNNNNNSNSNSNSNNNNIN 521
>sp|P54675|PI3K3_DICDI Phosphatidylinositol 3-kinase 3 (PI3-kinase) (PtdIns-3-kinase)
(PI3K)
Length = 1585
Score = 33.5 bits (75), Expect = 0.64
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 26/134 (19%)
Frame = +1
Query: 265 PLGDSGDSNRNFTRKRNRNIGKQR------------FRVSSLGESSTSGKNNHQAELNST 408
PL SG S+R FT +++ I + F ++ ++ + NN+ N+
Sbjct: 309 PLNISG-SSRFFTSRQDSKIDLLKSPSSSPPTQSDIFNENNNNNNNNNNNNNNNNNNNNN 367
Query: 409 RSFQNYKRHNKESALFKNKFPQ--ENWKDEKDESMLDQVLEATKI------------FDI 546
+ N +N E + N EN+K E+ E L ++LE K+ +I
Sbjct: 368 NNNNNNNNNNNEELINNNNNNNNDENYKIEETEESLKELLEKEKLENEEREKILKERNEI 427
Query: 547 DNNKQENRSGMGKY 588
DN K++N G +
Sbjct: 428 DNLKKKNHLSKGYF 441
>sp|P40872|PKSM_BACSU Putative polyketide synthase pksM
Length = 4262
Score = 33.5 bits (75), Expect = 0.64
Identities = 20/83 (24%), Positives = 35/83 (42%)
Frame = +1
Query: 373 GKNNHQAELNSTRSFQNYKRHNKESALFKNKFPQENWKDEKDESMLDQVLEATKIFDIDN 552
G+ H L+ R ++ H KE F WK S D++L +I++
Sbjct: 88 GQKQHGESLSDKRQYETADMHRKEQTAFAESIDLNQWK-----STADRILNLDEIYEQCR 142
Query: 553 NKQENRSGMGKYEPDKFYDCLSG 621
+++ +GM K E + Y+ G
Sbjct: 143 SQELVHTGMMKAE-GQIYEAKEG 164
>sp|P57458|IF2_BUCAI Translation initiation factor IF-2
Length = 864
Score = 32.3 bits (72), Expect = 1.4
Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Frame = +1
Query: 211 IKSIRIENKNFLNDSLIIPLG-DSGDSNRNFTRKRNRNIGKQRFRVSSLGESST------ 369
+K+ + EN++FLN+ +I S +N +K +NI K S +T
Sbjct: 93 VKNNKFENESFLNEKKVIKHSMQKTSSLKNKEKKYIKNIEKIELNKSDSRSLNTKKENKL 152
Query: 370 --SGKNNHQAELNSTRSFQNYKRHNKESALFKNKFPQENWKDEKDESMLDQVLEATKIFD 543
S K+ + N R ++ ++K+ + +NK + + K+EK + L L A + D
Sbjct: 153 KISNKDEQNKKFNQHRESNSFDLNHKK-RIKENKDIRISHKEEKQDYHLTTFLHARQAED 211
Query: 544 IDNNKQE 564
++ + E
Sbjct: 212 ENDREVE 218
>sp|O75400|FNBP3_HUMAN Formin-binding protein 3 (Huntingtin yeast partner A)
(Huntingtin-interacting protein HYPA/FBP11) (Fas-ligand
associated factor 1) (NY-REN-6 antigen)
Length = 957
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Frame = +1
Query: 274 DSGDSNRNFTRKRNRNIGKQRFRVSSLGESSTSGKNNHQAELNSTRSFQNYKRHNKESAL 453
DS D + + +KR R S + + H + S RS++ K+H K+S
Sbjct: 833 DSDDDDSHSKKKRQR--------------SESRSASEHSSSAESERSYKKSKKHKKKSKK 878
Query: 454 FKNK--FPQENWKDEKDESMLDQVLEATKIFDIDNNKQEN 567
++K P+ + + EKD+ D+ E + +K ++
Sbjct: 879 RRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKS 918
>sp|Q8N0V4|LGI2_HUMAN Leucine-rich repeat LGI family member 2 precursor (Leucine-rich
glioma-inactivated protein 2) (LGI1-like protein 2)
Length = 545
Score = 31.6 bits (70), Expect = 2.4
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Frame = +1
Query: 151 KSDSQFYPTHVAETLVNVEKIKSIRIENKNFLNDSLIIPLGDSGDSNRNFTRKRNRNIGK 330
KS +F P + +V +KS R++N +L SL +GDS N K
Sbjct: 403 KSSKKFVPHGDIPNMEDVLAVKSFRMQNTLYL--SLTRFIGDSRVMRWN---------SK 451
Query: 331 QRFRVSSLGESST------SGKNNHQAELNSTRSFQNYKRHNKESALFK 459
Q + +L S K+NH L S +F + +KE LFK
Sbjct: 452 QFVEIQALPSRGAMTLQPFSFKDNHYLALGSDYTFSQIYQWDKEKQLFK 500
>sp|P54673|PI3K1_DICDI Phosphatidylinositol 3-kinase 1 (PI3-kinase) (PtdIns-3-kinase)
(PI3K)
Length = 1570
Score = 31.6 bits (70), Expect = 2.4
Identities = 24/101 (23%), Positives = 42/101 (41%)
Frame = +1
Query: 148 IKSDSQFYPTHVAETLVNVEKIKSIRIENKNFLNDSLIIPLGDSGDSNRNFTRKRNRNIG 327
I +S TH+ N+ K S N N N+ II + ++ ++N+N N N
Sbjct: 14 INKNSNKNNTHLNSNYNNIYKNNSTSSNNNNNHNNIEIIGIDNNKNNNKNNNDNNNNN-- 71
Query: 328 KQRFRVSSLGESSTSGKNNHQAELNSTRSFQNYKRHNKESA 450
+++ + KN E+N S +N K +N +
Sbjct: 72 ------NNIDKKRKDSKNKQNQEINQEMS-ENKKIYNSNDS 105
>sp|Q06366|BXEN_CLOBU Botulinum neurotoxin type E, nontoxic component
Length = 1162
Score = 31.6 bits (70), Expect = 2.4
Identities = 30/145 (20%), Positives = 57/145 (39%), Gaps = 17/145 (11%)
Frame = +1
Query: 109 NEFKYLRMKNLDLIK--------------SDSQFYPTHVAETLVNVEKIKS---IRIENK 237
NEF L LD+I + F + +T N EK K+ I+I+N
Sbjct: 216 NEFNSLEYSELDMIDFLISGGIDYKLLNTNPYWFIDKYFIDTSKNFEKYKNDYEIKIKNN 275
Query: 238 NFLNDSLIIPLGDSGDSNRNFTRKRNRNIGKQRFRVSSLGESSTSGKNNHQAELNSTRSF 417
N++ +S+ + L N + N + + F++ + + + ++ E F
Sbjct: 276 NYIANSIKLYLEQKFKINVKDIWELNLSYFSKEFQIMMPERYNNALNHYYRKEFYVIDYF 335
Query: 418 QNYKRHNKESALFKNKFPQENWKDE 492
+NY + ++ K K P + E
Sbjct: 336 KNYNINGFKNGQIKTKLPLSKYNKE 360
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,562,425
Number of Sequences: 369166
Number of extensions: 1633302
Number of successful extensions: 4382
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4170
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4342
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)