Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02174
(683 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6MVH7|IPYR_NEUCR Inorganic pyrophosphatase (Pyrophospha... 205 8e-53
sp|Q9D819|IPYR_MOUSE Inorganic pyrophosphatase (Pyrophospha... 204 1e-52
sp|Q15181|IPYR_HUMAN Inorganic pyrophosphatase (Pyrophospha... 204 2e-52
sp|Q6FRB7|IPYR_CANGA Inorganic pyrophosphatase (Pyrophospha... 202 9e-52
sp|O77460|IPYR_DROME Inorganic pyrophosphatase (Pyrophospha... 202 9e-52
sp|Q9H2U2|IPYR2_HUMAN Inorganic pyrophosphatase 2, mitochon... 201 1e-51
sp|P37980|IPYR_BOVIN Inorganic pyrophosphatase (Pyrophospha... 199 4e-51
sp|O13505|IPYR_PICPA Inorganic pyrophosphatase (Pyrophospha... 199 6e-51
sp|Q6C1T4|IPYR_YARLI Inorganic pyrophosphatase (Pyrophospha... 198 1e-50
sp|Q18680|IPYR_CAEEL Probable inorganic pyrophosphatase (Py... 196 4e-50
>sp|Q6MVH7|IPYR_NEUCR Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 290
Score = 205 bits (522), Expect = 8e-53
Identities = 100/194 (51%), Positives = 128/194 (65%), Gaps = 1/194 (0%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGA PQTWEDPN I ET AKGDNDPLD+CEIG+ + G V VK LG++A++DE ETD
Sbjct: 96 YGAFPQTWEDPNSIHPETKAKGDNDPLDVCEIGELVGYTGQVKQVKVLGVMALLDEEETD 155
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WKVI I DPL KLND+ DVE+ +PGL+ T WF++YKIP KP N FAF GE KNK
Sbjct: 156 WKVIVIDVNDPLAPKLNDVEDVERHLPGLIRATNEWFRIYKIPDGKPENQFAFTGECKNK 215
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGSSFRISKDQVEAI-TNEALPLKAA 538
+ +++E NE+W++LI GK N+TV SS R++ DQ+ + NE LP
Sbjct: 216 TYAMDVVRECNEAWERLITGKTAPGGVSTTNVTVQHSSSRVAPDQLPPLPPNENLP---- 271
Query: 539 ETTIDPSVEIWHFV 580
ID S++ W F+
Sbjct: 272 PAPIDSSIDKWFFI 285
>sp|Q9D819|IPYR_MOUSE Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 289
Score = 204 bits (520), Expect = 1e-52
Identities = 100/190 (52%), Positives = 121/190 (63%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGAIPQTWEDP H D T GDNDP+D+CEIG K+ RG +I VK LGILAMIDEGETD
Sbjct: 94 YGAIPQTWEDPGHSDKHTGCCGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMIDEGETD 153
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WKVIAI DP + DISDVE+L PG L T WF+ YK+P KP N FAFN EFKNK
Sbjct: 154 WKVIAINVDDPDAANYKDISDVERLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKNK 213
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGSSFRISKDQVEAITNEALPLKAAE 541
DF IIK T++ W+ L+ K + + C N TV S F+ D +AI + P +
Sbjct: 214 DFAVDIIKSTHDYWKALVTKKTDGKGISCMNTTVSESPFKCDPDAAKAIVDALPPPCESA 273
Query: 542 TTIDPSVEIW 571
++ V+ W
Sbjct: 274 CSLPTDVDKW 283
>sp|Q15181|IPYR_HUMAN Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 289
Score = 204 bits (519), Expect = 2e-52
Identities = 99/190 (52%), Positives = 121/190 (63%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGAIPQTWEDP H D T GDNDP+D+CEIG K+ RG +I VK LGILAMIDEGETD
Sbjct: 94 YGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETD 153
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WKVIAI DP + NDI+DV++L PG L T WF+ YK+P KP N FAFN EFK+K
Sbjct: 154 WKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDK 213
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGSSFRISKDQVEAITNEALPLKAAE 541
DF IIK T++ W+ L+ K N + C N T+ S F+ D AI + P +
Sbjct: 214 DFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDALPPPCESA 273
Query: 542 TTIDPSVEIW 571
T+ V+ W
Sbjct: 274 CTVPTDVDKW 283
>sp|Q6FRB7|IPYR_CANGA Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 287
Score = 202 bits (513), Expect = 9e-52
Identities = 107/196 (54%), Positives = 127/196 (64%), Gaps = 3/196 (1%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGA PQTWEDPN ET A GDNDP+D+ EIG+ I G V VK LGI+A++DEGETD
Sbjct: 94 YGAFPQTWEDPNQTHPETKAVGDNDPVDVLEIGETIGYTGQVKQVKVLGIMALLDEGETD 153
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WKVIAI DPL KLNDI DVEK PGLL T WF++YKIP KP N FAF+GE KNK
Sbjct: 154 WKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNK 213
Query: 362 DFTKRIIKETNESWQKLIGGK-INTEDCKCENLTVGGSSFRISKDQVEAITNEALPLKA- 535
+ IIKETNESW++LI GK +++D EN V S + A A+P A
Sbjct: 214 KYALDIIKETNESWKQLIAGKSTDSKDIALENTKVTDSPY------YSASAASAIPAAAP 267
Query: 536 -AETTIDPSVEIWHFV 580
A+ ID SV+ W F+
Sbjct: 268 QADAPIDKSVDKWFFI 283
>sp|O77460|IPYR_DROME Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
(Nucleosome remodeling factor 38 kDa subunit)
Length = 338
Score = 202 bits (513), Expect = 9e-52
Identities = 97/193 (50%), Positives = 126/193 (65%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGA+PQTWE+P+HI+ T KGDNDP+D+ EIG ++ RG V+ VK LG +A+IDEGETD
Sbjct: 144 YGALPQTWENPDHIEPSTGCKGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETD 203
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WK+IAI DPL SK+NDI+DV++ PGLL T WFK+YKIP KP N FAFNG+ KN
Sbjct: 204 WKIIAIDVNDPLASKVNDIADVDQYFPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNA 263
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGSSFRISKDQVEAITNEALPLKAAE 541
DF II ET++ WQ L+ + N+T S I K++ E I EA P
Sbjct: 264 DFANTIIAETHKFWQNLVHQSPASGSISTTNITNRNSEHVIPKEEAEKILAEA-PDGGQV 322
Query: 542 TTIDPSVEIWHFV 580
+ +V+ WHF+
Sbjct: 323 EEVSDTVDTWHFI 335
>sp|Q9H2U2|IPYR2_HUMAN Inorganic pyrophosphatase 2, mitochondrial precursor (PPase 2)
(Pyrophosphatase SID6-306)
Length = 334
Score = 201 bits (511), Expect = 1e-51
Identities = 95/193 (49%), Positives = 123/193 (63%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YG +PQTWEDP+ D TN GDNDP+D+CEIG KI G VI VK LGILA+IDEGETD
Sbjct: 142 YGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEGETD 201
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WK+IAI DP SK +DI DV+K PG L T WF+LYK+P KP N FAFNGEFKNK
Sbjct: 202 WKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNK 261
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGSSFRISKDQVEAITNEALPLKAAE 541
F +IK T++ W+ L+ K N C N+ + S FR ++++ ++ E
Sbjct: 262 AFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKE 321
Query: 542 TTIDPSVEIWHFV 580
+ + ++WHF+
Sbjct: 322 S--NEEEQVWHFL 332
>sp|P37980|IPYR_BOVIN Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 289
Score = 199 bits (507), Expect = 4e-51
Identities = 98/190 (51%), Positives = 122/190 (64%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGAIPQTWEDP H D T GDNDP+D+CEIG K+ RG +I VK LGILAMIDEGETD
Sbjct: 94 YGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIRVKVLGILAMIDEGETD 153
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WKVIAI DP + NDI+DV++L PG L T WF+ YK+P KP N FAFN EFK+K
Sbjct: 154 WKVIAINVEDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDK 213
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGSSFRISKDQVEAITNEALPLKAAE 541
+F II+ T++ W+ L+ K + + C N TV S F+ D +AI + P +
Sbjct: 214 NFAIDIIESTHDYWRALVTKKTDGKGISCMNTTVSESPFQCDPDAAKAIVDALPPPCESA 273
Query: 542 TTIDPSVEIW 571
TI V+ W
Sbjct: 274 CTIPTDVDKW 283
>sp|O13505|IPYR_PICPA Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 285
Score = 199 bits (506), Expect = 6e-51
Identities = 101/194 (52%), Positives = 126/194 (64%), Gaps = 1/194 (0%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGA PQTWEDPN ET AKGDNDPLD+CEIG++ Y G V VK LG++A++DEGETD
Sbjct: 94 YGAFPQTWEDPNVTHPETKAKGDNDPLDVCEIGERSYT-GQVKQVKVLGVMALLDEGETD 152
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WKVI I DPL KLNDI DVEK MPGLL T WF++YKIP KP N FAF+GE KNK
Sbjct: 153 WKVIVIDINDPLAPKLNDIEDVEKHMPGLLRATNEWFRIYKIPDGKPENQFAFSGECKNK 212
Query: 362 DFTKRIIKETNESWQKLIGGKINTEDCKCENLTVGGS-SFRISKDQVEAITNEALPLKAA 538
+ + +I+E E+W+KLI GK + + N T+ + SF S + A P K
Sbjct: 213 KYAEEVIQECREAWEKLIFGKTSPGEIDLTNTTLQSTPSFSPSATSAVPTASPAAPAK-- 270
Query: 539 ETTIDPSVEIWHFV 580
ID S++ W ++
Sbjct: 271 ---IDQSIDKWFYI 281
>sp|Q6C1T4|IPYR_YARLI Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
Length = 287
Score = 198 bits (504), Expect = 1e-50
Identities = 98/199 (49%), Positives = 126/199 (63%), Gaps = 6/199 (3%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGA PQTWEDPNH+ ET AKGDNDPLD+CEIG+ + G V VK LG++A++DEGETD
Sbjct: 95 YGAFPQTWEDPNHVHPETKAKGDNDPLDVCEIGETVGYTGQVKQVKVLGVMALLDEGETD 154
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WK+IAI DPL SK+NDI DVE+ +PGLL T WF++YKIP KP N FAF+GE KNK
Sbjct: 155 WKIIAIDVKDPLASKVNDIEDVERHLPGLLRATNEWFRIYKIPDGKPENQFAFSGECKNK 214
Query: 362 DFTKRIIKETNESWQKLIGGK------INTEDCKCENLTVGGSSFRISKDQVEAITNEAL 523
+ +I+E E+W+ LI GK I+ E+ EN +S I + Q
Sbjct: 215 KYADEVIRECEEAWETLIAGKASDDKGISLENTTLENTPTFTASASIPEGQ--------- 265
Query: 524 PLKAAETTIDPSVEIWHFV 580
A ID S++ W ++
Sbjct: 266 --NLAPAPIDQSIDKWFYI 282
>sp|Q18680|IPYR_CAEEL Probable inorganic pyrophosphatase (Pyrophosphate
phospho-hydrolase) (PPase)
Length = 407
Score = 196 bits (499), Expect = 4e-50
Identities = 99/196 (50%), Positives = 126/196 (64%), Gaps = 3/196 (1%)
Frame = +2
Query: 2 YGAIPQTWEDPNHIDSETNAKGDNDPLDICEIGQKIYPRGSVIPVKPLGILAMIDEGETD 181
YGA+PQTWEDPNH+ +T AKGDNDP+D+ E+G K+ RG+V+ VK LG LA+IDEGETD
Sbjct: 217 YGALPQTWEDPNHVVPDTGAKGDNDPIDVIEVGSKVAGRGAVLQVKVLGTLALIDEGETD 276
Query: 182 WKVIAIAKGDPLESKLNDISDVEKLMPGLLNDTRRWFKLYKIPQDKPANTFAFNGEFKNK 361
WK++AI D KLNDI DVEK+ PGLL + WF+ YKIP KPAN FAFNGEFKN+
Sbjct: 277 WKLVAIDVNDENADKLNDIDDVEKVYPGLLAASVEWFRNYKIPAGKPANEFAFNGEFKNR 336
Query: 362 DFTKRIIKETNESWQKLI---GGKINTEDCKCENLTVGGSSFRISKDQVEAITNEALPLK 532
++ +++I ETNE W+ LI +NT E + G D+ A A P
Sbjct: 337 EYAEKVIDETNEYWKTLIKEANPSLNTVSRVPEAVHQG-------TDEAAATAIGATPEH 389
Query: 533 AAETTIDPSVEIWHFV 580
A + V+ WHFV
Sbjct: 390 GANAPLPGDVDKWHFV 405
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,845,054
Number of Sequences: 369166
Number of extensions: 1522617
Number of successful extensions: 4411
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4297
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4397
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5830600200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)