Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02157
(714 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9JLI7|SPAG6_MOUSE Sperm-associated antigen 6 (PF16 prot... 363 e-100
sp|O75602|SPAG6_HUMAN Sperm-associated antigen 6 (PF16 prot... 355 5e-98
sp|Q02821|IMA1_YEAST Importin alpha subunit (Karyopherin al... 46 9e-05
sp|Q9SLX0|IMA1B_ORYSA Importin alpha-1b subunit 46 9e-05
sp|P52293|IMA2_MOUSE Importin alpha-2 subunit (Karyopherin ... 43 0.001
sp|Q71VM4|IMA1A_ORYSA Importin alpha-1a subunit 43 0.001
sp|Q96321|IMA1_ARATH Importin alpha-1 subunit (Karyopherin ... 42 0.002
sp|O04294|IMA2_ARATH Importin alpha-2 subunit (Karyopherin ... 42 0.002
sp|Q64HA9|SPL11_ORYSA Spotted leaf protein 11 (Spotted leaf... 41 0.003
sp|P30998|PLAK_XENLA Junction plakoglobin (Desmoplakin III) 41 0.004
>sp|Q9JLI7|SPAG6_MOUSE Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central
apparatus protein)
Length = 507
Score = 363 bits (931), Expect = e-100
Identities = 183/237 (77%), Positives = 206/237 (86%)
Frame = +2
Query: 2 EPDLGLKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIA 181
EP++ LKRIAASALSDI KHSP+LAQTVVDAGAIAHLAQM+LNPD KLKRQ+ SAL+QIA
Sbjct: 178 EPEIALKRIAASALSDISKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIA 237
Query: 182 KHSVDLAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAA 361
KHSVDLAE+VVEAEIFP +LTCLKDKD+ VKKN TLIREIAKHTPELSQLIVNAGG+AA
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNACTLIREIAKHTPELSQLIVNAGGVAA 297
Query: 362 IVDFIGDTKGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATA 541
++D IG KGNI LPGIMMLGYVAAHSE LAM+VI+S+GV QLS + + EDHI AA A
Sbjct: 298 VIDCIGSCKGNIRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSICLSEEPEDHIKAAAA 357
Query: 542 WALGQIGRHTPEHAKAVAKQNILPKLLRCYLRPDVSEDLQNKSKKALKHILQKCVYL 712
WALGQ+GRHTPEHA+AVA N LP LL Y+ P+ SEDLQ KSKKA+K+ILQKC YL
Sbjct: 358 WALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPESSEDLQLKSKKAIKNILQKCTYL 414
Score = 103 bits (258), Expect = 3e-22
Identities = 58/203 (28%), Positives = 109/203 (53%)
Frame = +2
Query: 20 KRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDL 199
K+ AA L + KHSP LAQ +VD GA+ L + + D +K AL IA+H+ +L
Sbjct: 100 KKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTEL 159
Query: 200 AEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIG 379
++ VV+A P ++ C+++ + +K+ A+ + +I+KH+PEL+Q +V+AG IA + I
Sbjct: 160 SQAVVDAGAIPLLVLCIQEPEIALKRIAASALSDISKHSPELAQTVVDAGAIAHLAQMIL 219
Query: 380 DTKGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQI 559
+ + + L +A HS LA ++V + + D ++++ + +I
Sbjct: 220 NPDAKLKRQVLSALSQIAKHSVDLA-EMVVEAEIFPVVLTCLKDKDEYVKKNACTLIREI 278
Query: 560 GRHTPEHAKAVAKQNILPKLLRC 628
+HTPE ++ + + ++ C
Sbjct: 279 AKHTPELSQLIVNAGGVAAVIDC 301
Score = 95.5 bits (236), Expect = 1e-19
Identities = 62/216 (28%), Positives = 111/216 (51%)
Frame = +2
Query: 65 PDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEIVVEAEIFPAILT 244
P +T+ +AG ++ L ++L+ +++ AL ++A ++ DLAE VV+ +I P ++
Sbjct: 31 PQNIETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVY 90
Query: 245 CLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDTKGNISLPGIMMLG 424
L +++ KK A ++R + KH+P+L+Q IV+ G + +V + D + LG
Sbjct: 91 SLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALG 150
Query: 425 YVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVAKQN 604
Y+A H+ L+ +V V G + L + + E + A AL I +H+PE A+ V
Sbjct: 151 YIARHNTELSQAV-VDAGAIPLLVLCIQEPEIALKRIAASALSDISKHSPELAQTVVDAG 209
Query: 605 ILPKLLRCYLRPDVSEDLQNKSKKALKHILQKCVYL 712
+ L + L PD L+ + AL I + V L
Sbjct: 210 AIAHLAQMILNPDAK--LKRQVLSALSQIAKHSVDL 243
Score = 89.0 bits (219), Expect = 1e-17
Identities = 57/204 (27%), Positives = 100/204 (49%)
Frame = +2
Query: 17 LKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVD 196
+++ AA AL + ++ DLA+ VV + L + + K+ L + KHS
Sbjct: 57 IQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQ 116
Query: 197 LAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFI 376
LA+ +V+ ++ CL+D D VK+ A + IA+H ELSQ +V+AG I +V I
Sbjct: 117 LAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVLCI 176
Query: 377 GDTKGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQ 556
+ + + L ++ HS LA +V+ + + L+ + N + + AL Q
Sbjct: 177 QEPEIALKRIAASALSDISKHSPELAQTVVDAGAIAHLAQMILNP-DAKLKRQVLSALSQ 235
Query: 557 IGRHTPEHAKAVAKQNILPKLLRC 628
I +H+ + A+ V + I P +L C
Sbjct: 236 IAKHSVDLAEMVVEAEIFPVVLTC 259
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/143 (20%), Positives = 62/143 (43%)
Frame = +2
Query: 2 EPDLGLKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIA 181
EP+ +K AA AL + +H+P+ A+ V + L + ++P++ Q+ S A
Sbjct: 347 EPEDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPESSEDLQLKSKKA--- 403
Query: 182 KHSVDLAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAA 361
+ I+ + PA+ L D + K+ ++ H + +L V +GG+
Sbjct: 404 -----IKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKK 458
Query: 362 IVDFIGDTKGNISLPGIMMLGYV 430
+ + + PG ++ Y+
Sbjct: 459 VQEIKAE-------PGSLLQEYI 474
>sp|O75602|SPAG6_HUMAN Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar
protein) (Repro-SA-1)
Length = 509
Score = 355 bits (912), Expect = 5e-98
Identities = 178/237 (75%), Positives = 204/237 (86%)
Frame = +2
Query: 2 EPDLGLKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIA 181
EP++ LKRIAASALSDI KHSP+LAQTVVDAGA+AHLAQM+LNPD KLK QI SAL+Q++
Sbjct: 178 EPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVS 237
Query: 182 KHSVDLAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAA 361
KHSVDLAE+VVEAEIFP +LTCLKDKD+ VKKN +TLIREIAKHTPELSQL+VNAGG+AA
Sbjct: 238 KHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAA 297
Query: 362 IVDFIGDTKGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATA 541
++D IG KGN LPGIMMLGYVAAHSE LAM+VI+S+GV QLS + + EDHI AA A
Sbjct: 298 VIDCIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAA 357
Query: 542 WALGQIGRHTPEHAKAVAKQNILPKLLRCYLRPDVSEDLQNKSKKALKHILQKCVYL 712
WALGQIGRHTPEHA+AVA N LP LL Y+ + SEDLQ KSKKA+K+ILQKC YL
Sbjct: 358 WALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYL 414
Score = 103 bits (256), Expect = 6e-22
Identities = 59/203 (29%), Positives = 110/203 (54%)
Frame = +2
Query: 20 KRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDL 199
K+ AA L + KHSP LAQ +VD GA+ L + + D +K AL IA+H+ +L
Sbjct: 100 KKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAEL 159
Query: 200 AEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIG 379
++ VV+A P ++ C+++ + +K+ A+ + +IAKH+PEL+Q +V+AG +A + I
Sbjct: 160 SQAVVDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMIL 219
Query: 380 DTKGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQI 559
+ + + L V+ HS LA ++V + + D ++++ + + +I
Sbjct: 220 NPDAKLKHQILSALSQVSKHSVDLA-EMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREI 278
Query: 560 GRHTPEHAKAVAKQNILPKLLRC 628
+HTPE ++ V + ++ C
Sbjct: 279 AKHTPELSQLVVNAGGVAAVIDC 301
Score = 92.8 bits (229), Expect = 8e-19
Identities = 66/229 (28%), Positives = 112/229 (48%), Gaps = 5/229 (2%)
Frame = +2
Query: 17 LKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVD 196
+++ AA AL + ++ DLA+ VV + L + + K+ L + KHS
Sbjct: 57 IQQTAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQ 116
Query: 197 LAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFI 376
LA+ +V+ ++ CL+D D VK+ A +R IA+H ELSQ +V+AG + +V I
Sbjct: 117 LAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCI 176
Query: 377 GDTKGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQLSN-IFNNDC--EDHILAATAWA 547
+ + + L +A HS LA +V+ + V L+ I N D + IL+ A
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILS----A 232
Query: 548 LGQIGRHTPEHAKAVAKQNILPKLLRCYLRPD--VSEDLQNKSKKALKH 688
L Q+ +H+ + A+ V + I P +L C D V ++ ++ KH
Sbjct: 233 LSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH 281
Score = 91.3 bits (225), Expect = 2e-18
Identities = 60/216 (27%), Positives = 111/216 (51%)
Frame = +2
Query: 65 PDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEIVVEAEIFPAILT 244
P +T+ +AG ++ L ++L+ +++ AL ++A ++ DLAE VV+ +I P ++
Sbjct: 31 PQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKCDILPQLVY 90
Query: 245 CLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDTKGNISLPGIMMLG 424
L +++ KK A ++R + KH+P+L+Q IV+ G + +V + D + L
Sbjct: 91 SLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALR 150
Query: 425 YVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVAKQN 604
Y+A H+ L+ +V V G + L + + E + A AL I +H+PE A+ V
Sbjct: 151 YIARHNAELSQAV-VDAGAVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAG 209
Query: 605 ILPKLLRCYLRPDVSEDLQNKSKKALKHILQKCVYL 712
+ L + L PD L+++ AL + + V L
Sbjct: 210 AVAHLAQMILNPDAK--LKHQILSALSQVSKHSVDL 243
Score = 39.3 bits (90), Expect = 0.011
Identities = 30/143 (20%), Positives = 61/143 (42%)
Frame = +2
Query: 2 EPDLGLKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIA 181
EP+ +K AA AL I +H+P+ A+ V + L + ++ ++ Q+ S A
Sbjct: 347 EPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKA--- 403
Query: 182 KHSVDLAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAA 361
+ I+ + PA+ L D + K+ ++ H + +L V +GG+
Sbjct: 404 -----IKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKK 458
Query: 362 IVDFIGDTKGNISLPGIMMLGYV 430
+ + + PG ++ Y+
Sbjct: 459 VQEIKAE-------PGSLLQEYI 474
>sp|Q02821|IMA1_YEAST Importin alpha subunit (Karyopherin alpha subunit) (Serine-rich RNA
polymerase I suppressor protein)
Length = 542
Score = 46.2 bits (108), Expect = 9e-05
Identities = 49/250 (19%), Positives = 99/250 (39%), Gaps = 42/250 (16%)
Frame = +2
Query: 2 EPDLGLKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIA 181
+P++ L+ AA AL++I + + VVDA A+ Q++ ++K Q AL +A
Sbjct: 143 QPEM-LQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVA 201
Query: 182 KHSVDLAEIVVEAEIFPAILTCLK-DKDDMVKKNCATLIR------------EIAKHTPE 322
S D + V++ IL +K +++ TL +++ P
Sbjct: 202 GDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPT 261
Query: 323 LSQLIVNAG--------------------GIAAIVD---------FIGDTKGNISLPGIM 415
L++LI + I A++D + + P +
Sbjct: 262 LAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALR 321
Query: 416 MLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVA 595
+G + ++ L V+++ GVL + + +++I W + I E +AV
Sbjct: 322 AVGNIVTGND-LQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVI 380
Query: 596 KQNILPKLLR 625
N++P L++
Sbjct: 381 DANLIPPLVK 390
Score = 36.6 bits (83), Expect = 0.068
Identities = 24/116 (20%), Positives = 48/116 (41%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
A A+S + + Q V+D L +++ + T ++ A+ I + ++
Sbjct: 277 ACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQV 336
Query: 209 VVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFI 376
V+ A + PA+ L + +KK I I E Q +++A I +V +
Sbjct: 337 VINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLL 392
>sp|Q9SLX0|IMA1B_ORYSA Importin alpha-1b subunit
Length = 534
Score = 46.2 bits (108), Expect = 9e-05
Identities = 41/240 (17%), Positives = 92/240 (38%), Gaps = 42/240 (17%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
AA AL++I + D + VV++GA+ +++ +P ++ Q AL +A S ++
Sbjct: 142 AAWALTNIASGTSDNTKVVVESGAVPIFVKLLSSPSEDVREQAVWALGNVAGDSPKCRDL 201
Query: 209 VVEAE-IFP-----------------------------------------AILTCLKDKD 262
V+ + ++P A+ + +D
Sbjct: 202 VLASGGLYPLLQQLNEHAKLSMLRNATWTLSNFCRGKPQPNFEQVKPALSALQRLIHSQD 261
Query: 263 DMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDTKGNISLPGIMMLGYVAAHS 442
+ V + + ++ T + Q ++ +G +V+ + ++ +P + +G +
Sbjct: 262 EEVLTDACWALSYLSDGTNDKIQAVIESGVFPRLVELLMHPSASVLIPALRTVGNIVTGD 321
Query: 443 ETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVAKQNILPKLL 622
+ VI + + L N+ N+ + I W + I E +AV NI+ L+
Sbjct: 322 DMQTQCVIDHQALPCLLNLLTNNHKKSIKKEACWTISNITAGNREQIQAVINANIIAPLV 381
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/199 (18%), Positives = 82/199 (41%), Gaps = 1/199 (0%)
Frame = +2
Query: 56 KHSPDLAQTVVDAGAIAHLAQMVLNPD-TKLKRQIFSALAQIAKHSVDLAEIVVEAEIFP 232
+ SP + + V++ G + + D +L+ + AL IA + D ++VVE+ P
Sbjct: 109 ERSPPIEE-VINTGVVPRFIAFLQREDYPQLQFEAAWALTNIASGTSDNTKVVVESGAVP 167
Query: 233 AILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDTKGNISLPGI 412
+ L + V++ + +A +P+ L++ +GG+ ++ + + L
Sbjct: 168 IFVKLLSSPSEDVREQAVWALGNVAGDSPKCRDLVLASGGLYPLLQQLNEHAKLSMLRNA 227
Query: 413 MMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAV 592
+ V + L + ++ E+ +L WAL + T + +AV
Sbjct: 228 TWTLSNFCRGKPQPNFEQVKPALSALQRLIHSQDEE-VLTDACWALSYLSDGTNDKIQAV 286
Query: 593 AKQNILPKLLRCYLRPDVS 649
+ + P+L+ + P S
Sbjct: 287 IESGVFPRLVELLMHPSAS 305
Score = 39.3 bits (90), Expect = 0.011
Identities = 29/154 (18%), Positives = 62/154 (40%), Gaps = 1/154 (0%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
A ALS + + D Q V+++G L +++++P + + I +
Sbjct: 268 ACWALSYLSDGTNDKIQAVIESGVFPRLVELLMHPSASVLIPALRTVGNIVTGDDMQTQC 327
Query: 209 VVEAEIFPAILTCLKDKDDM-VKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDT 385
V++ + P +L L + +KK I I E Q ++NA IA +V +
Sbjct: 328 VIDHQALPCLLNLLTNNHKKSIKKEACWTISNITAGNREQIQAVINANIIAPLVHLLQTA 387
Query: 386 KGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQ 487
+ +I + + + +V++G ++
Sbjct: 388 EFDIKKEAAWAISNATSGGTHDQIKYLVAQGCIK 421
>sp|P52293|IMA2_MOUSE Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha)
(RAG cohort protein 1) (Pendulin) (Pore targeting
complex 58 kDa subunit) (PTAC58) (Importin alpha P1)
Length = 529
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/252 (17%), Positives = 91/252 (36%), Gaps = 47/252 (18%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
+A AL++I + + + VVD GAI ++ +P + Q AL IA ++
Sbjct: 140 SAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL 199
Query: 209 VVEAEIFPAILTCLKDKD-----------------------------DMVKKNCATLIRE 301
V++ +L L D D V++ TL+R
Sbjct: 200 VIKHGAIDPLLALLAVPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRL 259
Query: 302 IAKHTPEL------------------SQLIVNAGGIAAIVDFIGDTKGNISLPGIMMLGY 427
+ + PE+ +++V G + +V +G T+ I P + +G
Sbjct: 260 LHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGN 319
Query: 428 VAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVAKQNI 607
+ ++ VI + + ++ N + +I W + I + + V +
Sbjct: 320 IVTGTDEQTQKVIDAGALAVFPSLLTNP-KTNIQKEATWTMSNITAGRQDQIQQVVNHGL 378
Query: 608 LPKLLRCYLRPD 643
+P L+ + D
Sbjct: 379 VPFLVGVLSKAD 390
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
A A+ +I + + Q V+DAGA+A ++ NP T ++++ ++ I D +
Sbjct: 313 ALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQ 372
Query: 209 VVEAEIFPAILTCLKDKDDMVKKNCATLIREIAK-HTPELSQLIVNAGGIAAIVDFIG-- 379
VV + P ++ L D +K A I T E +V+ G I +++ +
Sbjct: 373 VVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK 432
Query: 380 DTK 388
DTK
Sbjct: 433 DTK 435
>sp|Q71VM4|IMA1A_ORYSA Importin alpha-1a subunit
Length = 526
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/154 (19%), Positives = 64/154 (41%), Gaps = 1/154 (0%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
A ALS + + D Q V++AG L +++L+P + + I +
Sbjct: 262 ACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQC 321
Query: 209 VVEAEIFPAILTCL-KDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDT 385
+++ + P +L+ L ++ +KK I I + Q ++NAG I +V+ +
Sbjct: 322 IIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTA 381
Query: 386 KGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQ 487
+ +I + + + +VS G ++
Sbjct: 382 EFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIK 415
>sp|Q96321|IMA1_ARATH Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (KAP alpha)
Length = 532
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/194 (18%), Positives = 78/194 (40%), Gaps = 1/194 (0%)
Frame = +2
Query: 56 KHSPDLAQTVVDAGAIAHLAQMVLNPD-TKLKRQIFSALAQIAKHSVDLAEIVVEAEIFP 232
+ SP + + V+ AG + + + D ++ + AL IA + D ++V++ P
Sbjct: 103 ERSPPIEE-VISAGVVPRFVEFLKKEDYPAIQFEAAWALTNIASGTSDHTKVVIDHNAVP 161
Query: 233 AILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDTKGNISLPGI 412
+ L D V++ + +A +P L++ G + +++ + + L
Sbjct: 162 IFVQLLASPSDDVREQAVWALGNVAGDSPRCRDLVLGCGALLPLLNQLNEHAKLSMLRNA 221
Query: 413 MMLGYVAAHSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAV 592
+ V + L + ++D E+ +L WAL + T + + V
Sbjct: 222 TWTLSNFCRGKPQPHFDQVKPALPALERLIHSDDEE-VLTDACWALSYLSDGTNDKIQTV 280
Query: 593 AKQNILPKLLRCYL 634
+ ++PKL+ L
Sbjct: 281 IQAGVVPKLVELLL 294
Score = 33.9 bits (76), Expect = 0.44
Identities = 28/154 (18%), Positives = 60/154 (38%), Gaps = 1/154 (0%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
A ALS + + D QTV+ AG + L +++L+ + + I +
Sbjct: 262 ACWALSYLSDGTNDKIQTVIQAGVVPKLVELLLHHSPSVLIPALRTVGNIVTGDDIQTQC 321
Query: 209 VVEAEIFPAILTCL-KDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDT 385
V+ + P + L ++ +KK I I + Q +V A I+ +V + +
Sbjct: 322 VINSGALPCLANLLTQNHKKSIKKEACWTISNITAGNKDQIQTVVEANLISPLVSLLQNA 381
Query: 386 KGNISLPGIMMLGYVAAHSETLAMSVIVSRGVLQ 487
+ +I + + + +V +G ++
Sbjct: 382 EFDIKKEAAWAISNATSGGSHDQIKYLVEQGCIK 415
Score = 30.0 bits (66), Expect = 6.4
Identities = 16/51 (31%), Positives = 27/51 (52%)
Frame = +2
Query: 539 AWALGQIGRHTPEHAKAVAKQNILPKLLRCYLRPDVSEDLQNKSKKALKHI 691
AWAL I T +H K V N +P ++ P S+D++ ++ AL ++
Sbjct: 137 AWALTNIASGTSDHTKVVIDHNAVPIFVQLLASP--SDDVREQAVWALGNV 185
>sp|O04294|IMA2_ARATH Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (KAP alpha)
Length = 531
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/183 (17%), Positives = 79/183 (43%), Gaps = 2/183 (1%)
Frame = +2
Query: 83 VVDAGAIAHLAQMVLNPD-TKLKRQIFSALAQIAKHSVDLAEIVVEAEIFPAILTCLKDK 259
VV +G + + + + D KL+ + AL IA + + +++E+ P + L
Sbjct: 114 VVQSGVVPRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSA 173
Query: 260 DDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIVD-FIGDTKGNISLPGIMMLGYVAA 436
+ V++ + +A +P+ L+++ G + ++ F +TK ++ L
Sbjct: 174 SEDVREQAVWALGNVAGDSPKCRDLVLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCR 233
Query: 437 HSETLAMSVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVAKQNILPK 616
A ++ L + ++ +L WAL + ++ + +AV + ++P+
Sbjct: 234 GKPPPAFEQ--TQPALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPR 291
Query: 617 LLR 625
L++
Sbjct: 292 LIQ 294
Score = 39.3 bits (90), Expect = 0.011
Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 1/114 (0%)
Frame = +2
Query: 29 AASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEI 208
A ALS + +S D Q V++AG + L Q++ + + + I ++
Sbjct: 265 ACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIVTGDDLQTQM 324
Query: 209 VVEAEIFPAILTCLKDK-DDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAIV 367
V++ + P +L LK+ +KK I I + Q +++AG I ++V
Sbjct: 325 VLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGNADQIQAVIDAGIIQSLV 378
>sp|Q64HA9|SPL11_ORYSA Spotted leaf protein 11 (Spotted leaf11) (Cell death-related
protein SPL11)
Length = 694
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/126 (24%), Positives = 60/126 (47%)
Frame = +2
Query: 5 PDLGLKRIAASALSDICKHSPDLAQTVVDAGAIAHLAQMVLNPDTKLKRQIFSALAQIAK 184
PD +R AA+ L + K + + + +AGAI L ++ + D + + +AL ++
Sbjct: 379 PDTEEQRSAAAELRLLAKRNANNRICIAEAGAIPLLLSLLSSSDLRTQEHAVTALLNLSI 438
Query: 185 HSVDLAEIVVEAEIFPAILTCLKDKDDMVKKNCATLIREIAKHTPELSQLIVNAGGIAAI 364
H + A I+ + P+I+ LK+ ++N A + ++ E I G I A+
Sbjct: 439 HEDNKASIISSGAV-PSIVHVLKNGSMEARENAAATLFSLSV-IDEYKVTIGGMGAIPAL 496
Query: 365 VDFIGD 382
V +G+
Sbjct: 497 VVLLGE 502
>sp|P30998|PLAK_XENLA Junction plakoglobin (Desmoplakin III)
Length = 738
Score = 40.8 bits (94), Expect = 0.004
Identities = 45/202 (22%), Positives = 85/202 (42%)
Frame = +2
Query: 98 AIAHLAQMVLNPDTKLKRQIFSALAQIAKHSVDLAEIVVEAEIFPAILTCLKDKDDMVKK 277
AI L +++ + D + + + Q++K ++ +I AI+ ++ DM
Sbjct: 139 AIPELTKLLNDEDPMVVNKASMIVNQLSKKEASRKALMQSPQIVAAIVRTMQHTSDMDTA 198
Query: 278 NCATLIREIAKHTPELSQLIVNAGGIAAIVDFIGDTKGNISLPGIMMLGYVAAHSETLAM 457
C T I H E I +GGI A+V + ++ I L + + E M
Sbjct: 199 RCTTSILHNLSHHREGLLSIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKM 258
Query: 458 SVIVSRGVLQLSNIFNNDCEDHILAATAWALGQIGRHTPEHAKAVAKQNILPKLLRCYLR 637
+V ++ G+ ++ + N + LA T L Q+ + + +K + N P+ L +R
Sbjct: 259 AVRLADGLQKMVPLLNKN-NPKFLAITTDCL-QLLAYGNQESKLIILGNGGPQGLVQIMR 316
Query: 638 PDVSEDLQNKSKKALKHILQKC 703
E L + + LK +L C
Sbjct: 317 NYNYEKLLWTTSRVLK-VLSVC 337
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,320,257
Number of Sequences: 369166
Number of extensions: 1564131
Number of successful extensions: 4934
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4647
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4908
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6316483550
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)