Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02149
(430 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 (p... 170 1e-42
sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 ... 170 1e-42
sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 ... 169 2e-42
sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 ... 169 2e-42
sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 ... 169 3e-42
sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 (p... 166 1e-41
sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 ... 165 3e-41
sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 (p... 164 7e-41
sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 ... 163 1e-40
sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 ... 163 1e-40
>sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2) (Gamma-PAK) (p62-PAK)
Length = 524
Score = 170 bits (430), Expect = 1e-42
Identities = 81/114 (71%), Positives = 97/114 (85%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 406 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 465
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +SP+F DF++ CLE+DVEKR +A LL+H F ++ +KP+S L PLIL A+E
Sbjct: 466 PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF-LKLAKPLSSLTPLILAAKE 518
>sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2)
Length = 524
Score = 170 bits (430), Expect = 1e-42
Identities = 81/114 (71%), Positives = 97/114 (85%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 406 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 465
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +SP+F DF++ CLE+DVEKR +A LL+H F ++ +KP+S L PLIL A+E
Sbjct: 466 PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF-LKLAKPLSSLTPLILAAKE 518
>sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase)
Length = 524
Score = 169 bits (428), Expect = 2e-42
Identities = 80/114 (70%), Positives = 97/114 (85%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 406 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 465
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +SP+F DF++ CLE+DVEKR +A LL+H F ++ +KP+S L PLI+ A+E
Sbjct: 466 PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF-LKLAKPLSSLTPLIMAAKE 518
>sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
(PAK-2) (Gamma-PAK) (p21-activated protein kinase I)
(PAKI)
Length = 524
Score = 169 bits (428), Expect = 2e-42
Identities = 80/114 (70%), Positives = 97/114 (85%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 406 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 465
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +SP+F DF++ CLE+DVEKR +A LL+H F ++ +KP+S L PLI+ A+E
Sbjct: 466 PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF-LKLAKPLSSLTPLIMAAKE 518
>sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 (p21-activated kinase 1)
(PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase
PAK-A)
Length = 545
Score = 169 bits (427), Expect = 3e-42
Identities = 79/117 (67%), Positives = 98/117 (83%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 427 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN 486
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLAREQSE 351
P +S +F DF+ CCLE+DVEKR +A LL+H+F ++ +KP+S L PL+ A+E ++
Sbjct: 487 PEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQF-LKIAKPLSSLTPLMHAAKEATK 542
>sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 (p21-activated kinase 1)
(PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2)
Length = 544
Score = 166 bits (421), Expect = 1e-41
Identities = 79/117 (67%), Positives = 98/117 (83%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 426 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN 485
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLAREQSE 351
P +S +F DF++ CLE+DVEKR +A LL+H+F ++ +KP+S L PLI A+E ++
Sbjct: 486 PEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF-LKIAKPLSSLTPLIAAAKEATK 541
>sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 (p21-activated kinase 1)
(PAK-1) (P65-PAK) (Alpha-PAK)
Length = 545
Score = 165 bits (418), Expect = 3e-41
Identities = 78/117 (66%), Positives = 98/117 (83%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 427 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN 486
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLAREQSE 351
P +S +F DF++ CL++DVEKR +A LL+H+F ++ +KP+S L PLI A+E ++
Sbjct: 487 PEKLSAIFRDFLNRCLDMDVEKRGSAKELLQHQF-LKIAKPLSSLTPLIAAAKEATK 542
>sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3) (Beta-PAK) (p65-PAK)
Length = 544
Score = 164 bits (415), Expect = 7e-41
Identities = 78/114 (68%), Positives = 96/114 (84%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 425 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 484
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +S +F DF++ CLE+DV++R +A LL+H F ++ +KP+S L PLIL A+E
Sbjct: 485 PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF-LKLAKPLSSLTPLILAAKE 537
>sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3) (Beta-PAK) (Oligophrenin-3)
sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3)
sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3)
Length = 559
Score = 163 bits (413), Expect = 1e-40
Identities = 77/114 (67%), Positives = 96/114 (84%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 440 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 499
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +S +F DF++ CLE+DV++R +A LL+H F ++ +KP+S L PLI+ A+E
Sbjct: 500 PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF-LKLAKPLSSLTPLIIAAKE 552
>sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 (p21-activated kinase 3)
(PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B)
Length = 559
Score = 163 bits (413), Expect = 1e-40
Identities = 77/114 (67%), Positives = 96/114 (84%)
Frame = +1
Query: 1 TPYWMAPEVVTRKQYGPKVDLWSLGIMVIEMLEGEPPYLNENPLRALYLIATNGKPLLKD 180
TPYWMAPEVVTRK YGPKVD+WSLGIM IEM+EGEPPYLNENPLRALYLIATNG P L++
Sbjct: 440 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN 499
Query: 181 PSAVSPLFLDFMDCCLEVDVEKRATASSLLKHEFIIEKSKPVSILIPLILLARE 342
P +S +F DF++ CLE+DV++R +A LL+H F ++ +KP+S L PLI+ A+E
Sbjct: 500 PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF-LKLAKPLSSLTPLIIAAKE 552
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,070,857
Number of Sequences: 369166
Number of extensions: 944289
Number of successful extensions: 4180
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3710
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3925
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2095022160
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)