Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02138
(778 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26619|KAPR_STRPU cAMP-dependent protein kinase type II ... 126 8e-29
sp|P81900|KAPR2_DROME cAMP-dependent protein kinase type II... 125 1e-28
sp|P31322|KAP3_BOVIN cAMP-dependent protein kinase type II-... 122 1e-27
sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II-... 121 2e-27
sp|Q8TF77|KAPR_RHIRA cAMP-dependent protein kinase regulato... 121 2e-27
sp|P12369|KAP3_RAT cAMP-dependent protein kinase type II-be... 120 3e-27
sp|P31324|KAP3_MOUSE cAMP-dependent protein kinase type II-... 120 4e-27
sp|P00515|KAP2_BOVIN cAMP-dependent protein kinase type II-... 119 1e-26
sp|P13861|KAP2_HUMAN cAMP-dependent protein kinase type II-... 119 1e-26
sp|P12368|KAP2_RAT cAMP-dependent protein kinase type II-al... 117 3e-26
>sp|Q26619|KAPR_STRPU cAMP-dependent protein kinase type II regulatory subunit
Length = 369
Score = 126 bits (316), Expect = 8e-29
Identities = 78/217 (35%), Positives = 115/217 (52%), Gaps = 3/217 (1%)
Frame = +1
Query: 100 RHGVTAEKVDPR--NATXXXXXXXXXXXXXXVEQIKSSLKSIFLFEGLEENETNEMISFM 273
R V AEK DP N T ++ ++K+I LF L+E + E+I M
Sbjct: 79 RKSVCAEKYDPEADNDTDTQKLVYPKSDEQRA-RLTEAVKNILLFRALDEKQMQEVIDAM 137
Query: 274 SYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYKGGKLLKKYENSGYFGELALLYNTPRNA 453
D GDNFYVI++G ++ + + Y++SG FGELAL+YNTPR A
Sbjct: 138 FEKKTTPGDHVIDQGDDGDNFYVIDRGEYDIFVNDNKVGAYKDSGSFGELALMYNTPRAA 197
Query: 454 TVIATSDGQLWSLDRNSFQRHVLQHAFDKRKRSELLVRKCDILKNLLEHEIIMIIDSLKF 633
T+ AT+DG LW+LDR SF+R VL++A KR+ E L+ K I K+L +E + + D+L
Sbjct: 198 TIAATTDGILWALDRVSFRRIVLKNAAKKRRIYEELLEKVSIFKSLEPYERMNLADALVT 257
Query: 634 QTISN-KILFKEGENNDVIYLIDDGEVEIIKKLNGED 741
+T + + +G+ D Y I+ G+ I K D
Sbjct: 258 RTYEDGDCIIAQGDGADGCYFIEAGQCRIAMKSERSD 294
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/140 (30%), Positives = 54/140 (38%), Gaps = 9/140 (6%)
Frame = +1
Query: 208 LKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFE-AYKGG-- 378
L+ + +F+ LE E + + D D Y IE G A K
Sbjct: 234 LEKVSIFKSLEPYERMNLADALVTRTYEDGDCIIAQGDGADGCYFIEAGQCRIAMKSERS 293
Query: 379 ------KLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
K + Y YFGELALL N PR A+V A D LD N+F+R
Sbjct: 294 DNPDEEKEVAIYNQGQYFGELALLTNKPRAASVYAVEDVDC-LLDVNAFER--------- 343
Query: 541 RKRSELLVRKCDILKNLLEH 600
LL DI+K +EH
Sbjct: 344 -----LLGPCMDIMKRNIEH 358
>sp|P81900|KAPR2_DROME cAMP-dependent protein kinase type II regulatory subunit
Length = 377
Score = 125 bits (315), Expect = 1e-28
Identities = 68/193 (35%), Positives = 113/193 (58%), Gaps = 1/193 (0%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYK 372
++ S+K++ LF LE+ + N+++ M D GDNFYVIE G ++ Y
Sbjct: 114 RLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYI 173
Query: 373 GGKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDKRKRS 552
K + Y ++G FGELALLYN PR ATV A + G LW++DR +F+R +L+ AF KRK
Sbjct: 174 NDKHINTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMY 233
Query: 553 ELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEIIKKL 729
E L+ +LK L +E + + D+L ++ N + + K+G+ D +Y I++G V + ++
Sbjct: 234 EELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSV--RM 291
Query: 730 NGEDVVKKVLKTG 768
+ +D ++ + G
Sbjct: 292 DQDDAEVEISQLG 304
Score = 35.8 bits (81), Expect = 0.13
Identities = 33/120 (27%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Frame = +1
Query: 208 LKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGT----FEAYKG 375
L S+ + + L+ E + + D D Y IE+GT +
Sbjct: 237 LNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDA 296
Query: 376 GKLLKKYENSGYFGELALLYNTPRNATVIATSD-GQLWSLDRNSFQRHVLQHAFDKRKRS 552
+ + YFGELAL+ + PR A+V AT +L LD +F+R +L D KR+
Sbjct: 297 EVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFER-LLGPCMDIMKRN 355
>sp|P31322|KAP3_BOVIN cAMP-dependent protein kinase type II-beta regulatory subunit
Length = 418
Score = 122 bits (305), Expect = 1e-27
Identities = 64/192 (33%), Positives = 111/192 (57%), Gaps = 5/192 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYK 372
+++ + K I LF+ L+ + ++++ M D GDNFYVI++GTF+ Y
Sbjct: 144 RLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV 203
Query: 373 G----GKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
G+ + Y+N G FGELAL+YNTPR AT+ ATS G LW LDR +F+R ++++ K
Sbjct: 204 KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK 263
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + LK+L E + ++D + + ++ + + +G++ D ++++ GEV+I
Sbjct: 264 RKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKI 323
Query: 718 IKKLNGEDVVKK 753
K G+ V++
Sbjct: 324 TMKRKGKSEVEE 335
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 11/116 (9%)
Frame = +1
Query: 199 KSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYKGG 378
+S ++S+ + LE +E +++ + D D+F+++E G +
Sbjct: 268 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKR 327
Query: 379 KLLKKYENSG-----------YFGELALLYNTPRNATVIATSDGQLWSLDRNSFQR 513
K + E +G YFGELAL+ N PR A+ A + ++D +F+R
Sbjct: 328 KGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFER 383
>sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II-beta regulatory subunit
Length = 418
Score = 121 bits (304), Expect = 2e-27
Identities = 64/192 (33%), Positives = 111/192 (57%), Gaps = 5/192 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYK 372
+++ + K I LF+ L+ + ++++ M D GDNFYVI++GTF+ Y
Sbjct: 144 RLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYV 203
Query: 373 G----GKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
G+ + Y+N G FGELAL+YNTPR AT+ ATS G LW LDR +F+R ++++ K
Sbjct: 204 KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK 263
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + LK+L E + ++D + + ++ + + +G++ D ++++ GEV+I
Sbjct: 264 RKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKI 323
Query: 718 IKKLNGEDVVKK 753
K G+ V++
Sbjct: 324 TMKRKGKSEVEE 335
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 11/116 (9%)
Frame = +1
Query: 199 KSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYKGG 378
+S ++S+ + LE +E +++ + D D+F+++E G +
Sbjct: 268 ESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKR 327
Query: 379 KLLKKYENSG-----------YFGELALLYNTPRNATVIATSDGQLWSLDRNSFQR 513
K + E +G YFGELAL+ N PR A+ A + ++D +F+R
Sbjct: 328 KGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFER 383
>sp|Q8TF77|KAPR_RHIRA cAMP-dependent protein kinase regulatory subunit (PKA regulatory
subunit)
Length = 427
Score = 121 bits (303), Expect = 2e-27
Identities = 68/198 (34%), Positives = 110/198 (55%), Gaps = 3/198 (1%)
Frame = +1
Query: 190 EQIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAY 369
E+IK S+ + FLF L+E + ++++ MS GD FYV+E GT + +
Sbjct: 174 ERIKVSISNNFLFRNLDEEQYLDVVNAMSEKRVVKGTTVIEQGSVGDFFYVVESGTLDCF 233
Query: 370 KGGKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDKRKR 549
G + YE G FGELAL+YN PR AT+I TSD LW+LDRN+ ++++ KR+
Sbjct: 234 IGQNKVTNYEAGGSFGELALMYNAPRAATIITTSDSVLWALDRNTSAPSLMENTSRKRRM 293
Query: 550 SELLVRKCDILKNL---LEHEIIMIIDSLKFQTISNKILFKEGENNDVIYLIDDGEVEII 720
E + + +LK+L +H+I ++S+ F+ + + K+G+ D Y+I+ GE ++
Sbjct: 294 YEYFLSEVVLLKSLESYEQHKIADALESVYFE--DGQEVVKQGDVGDQFYIIESGEAIVL 351
Query: 721 KKLNGEDVVKKVLKTGCY 774
K+ NG L+ G Y
Sbjct: 352 KEENGVQQQVNQLERGSY 369
Score = 49.7 bits (117), Expect = 9e-06
Identities = 36/119 (30%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +1
Query: 208 LKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYKGG--- 378
L + L + LE E +++ + D GD FY+IE G K
Sbjct: 298 LSEVVLLKSLESYEQHKIADALESVYFEDGQEVVKQGDVGDQFYIIESGEAIVLKEENGV 357
Query: 379 -KLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDKRKRS 552
+ + + E YFGELALL + PR ATV+A + +L + +F R +L D KR+
Sbjct: 358 QQQVNQLERGSYFGELALLNDAPRAATVVAHGRLKCATLGKKAFTR-LLGPVLDILKRN 415
>sp|P12369|KAP3_RAT cAMP-dependent protein kinase type II-beta regulatory subunit
Length = 416
Score = 120 bits (302), Expect = 3e-27
Identities = 63/192 (32%), Positives = 110/192 (57%), Gaps = 5/192 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYK 372
+++ + K I LF+ L+ + ++++ M D GDNFYVI++GTF+ Y
Sbjct: 142 RLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV 201
Query: 373 G----GKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
G+ + Y+N G FGELAL+YNTPR AT+ ATS G LW LDR +F+R ++++ K
Sbjct: 202 KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK 261
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + LK+L E + ++D + + ++ + + +G++ D ++++ GEV I
Sbjct: 262 RKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRI 321
Query: 718 IKKLNGEDVVKK 753
K G+ +++
Sbjct: 322 TMKRKGKSDIEE 333
Score = 40.4 bits (93), Expect = 0.005
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 11/116 (9%)
Frame = +1
Query: 199 KSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYKGG 378
+S ++S+ + LE +E +++ + D D+F+++E G
Sbjct: 266 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRITMKR 325
Query: 379 KLLKKYENSG-----------YFGELALLYNTPRNATVIATSDGQLWSLDRNSFQR 513
K E +G YFGELAL+ N PR A+ A + ++D +F+R
Sbjct: 326 KGKSDIEENGAVEIARCLRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFER 381
>sp|P31324|KAP3_MOUSE cAMP-dependent protein kinase type II-beta regulatory subunit
Length = 416
Score = 120 bits (301), Expect = 4e-27
Identities = 64/192 (33%), Positives = 110/192 (57%), Gaps = 5/192 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYK 372
+++ + K I LF+ L+ + ++++ M D GDNFYVI++GTF+ Y
Sbjct: 142 RLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV 201
Query: 373 G----GKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
G+ + Y+N G FGELAL+YNTPR AT+ ATS G LW LDR +F+R ++++ K
Sbjct: 202 KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK 261
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + LK+L E + ++D + + ++ + + +G+ D ++++ GEV+I
Sbjct: 262 RKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKI 321
Query: 718 IKKLNGEDVVKK 753
K G+ V++
Sbjct: 322 TMKRKGKSEVEE 333
Score = 40.8 bits (94), Expect = 0.004
Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 11/116 (9%)
Frame = +1
Query: 199 KSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAYKGG 378
+S ++S+ + LE +E +++ + D D+F+++E G +
Sbjct: 266 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKR 325
Query: 379 KLLKKYENSG-----------YFGELALLYNTPRNATVIATSDGQLWSLDRNSFQR 513
K + E +G YFGELAL+ N PR A+ A + ++D +F+R
Sbjct: 326 KGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFER 381
>sp|P00515|KAP2_BOVIN cAMP-dependent protein kinase type II-alpha regulatory subunit
Length = 400
Score = 119 bits (297), Expect = 1e-26
Identities = 64/183 (34%), Positives = 106/183 (57%), Gaps = 5/183 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAY- 369
+++ + K I LF+ L+ + ++++ M D GDNFYVIE+GT++
Sbjct: 125 RLQEACKDILLFKNLDPEQLSQVLDAMFERTVKVDEHVIDQGDDGDNFYVIERGTYDILV 184
Query: 370 ---KGGKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
+ + +Y+N G FGELAL+YNTPR AT++ATS+G LW LDR +F+R ++++ K
Sbjct: 185 TKDNQTRSVGQYDNHGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKK 244
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + +LK+L E + I+D + + + + + +GE D Y+I+ GEV I
Sbjct: 245 RKMFESFIESVPLLKSLEVSERMKIVDVIGEKVYKDGERIITQGEKADSFYIIESGEVSI 304
Query: 718 IKK 726
+ K
Sbjct: 305 LIK 307
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 12/133 (9%)
Frame = +1
Query: 190 EQIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAY 369
+ +S ++S+ L + LE +E +++ + + D+FY+IE G
Sbjct: 246 KMFESFIESVPLLKSLEVSERMKIVDVIGEKVYKDGERIITQGEKADSFYIIESGEVSIL 305
Query: 370 KGGKL------------LKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQR 513
K + + YFGELAL+ N PR A+ A D + +D +F+R
Sbjct: 306 IKSKTKVNKDGENQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFER 365
Query: 514 HVLQHAFDKRKRS 552
+L D KR+
Sbjct: 366 -LLGPCMDIMKRN 377
>sp|P13861|KAP2_HUMAN cAMP-dependent protein kinase type II-alpha regulatory subunit
Length = 404
Score = 119 bits (297), Expect = 1e-26
Identities = 63/181 (34%), Positives = 106/181 (58%), Gaps = 5/181 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAY- 369
+++ + K I LF+ L++ + ++++ M D GDNFYVIE+GT++
Sbjct: 129 RLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILV 188
Query: 370 ---KGGKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
+ + +Y+N G FGELAL+YNTPR AT++ATS+G LW LDR +F+R ++++ K
Sbjct: 189 TKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKK 248
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + +LK+L E + I+D + + + + + +GE D Y+I+ GEV I
Sbjct: 249 RKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSI 308
Query: 718 I 720
+
Sbjct: 309 L 309
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/133 (26%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Frame = +1
Query: 190 EQIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKG----- 354
+ +S ++S+ L + LE +E +++ + + D+FY+IE G
Sbjct: 250 KMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSIL 309
Query: 355 ----TFEAYKGGKL---LKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQR 513
T GG + + YFGELAL+ N PR A+ A D + +D +F+R
Sbjct: 310 IRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFER 369
Query: 514 HVLQHAFDKRKRS 552
+L D KR+
Sbjct: 370 -LLGPCMDIMKRN 381
>sp|P12368|KAP2_RAT cAMP-dependent protein kinase type II-alpha regulatory subunit
Length = 370
Score = 117 bits (294), Expect = 3e-26
Identities = 63/181 (34%), Positives = 104/181 (57%), Gaps = 5/181 (2%)
Frame = +1
Query: 193 QIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAY- 369
+++ + K I LF+ L++ + ++++ M D GDNFYVIE+GT++
Sbjct: 95 RLQEACKDILLFKNLDQEQLSQVLDAMFKRIVKTDEHVIDQGDDGDNFYVIERGTYDILV 154
Query: 370 ---KGGKLLKKYENSGYFGELALLYNTPRNATVIATSDGQLWSLDRNSFQRHVLQHAFDK 540
+ + +Y N G FGELAL+YNTPR AT++ATSDG LW LDR +F+R ++++ K
Sbjct: 155 TKDNQTRSVGQYANRGSFGELALMYNTPRAATIVATSDGSLWGLDRVTFRRIIVKNNAKK 214
Query: 541 RKRSELLVRKCDILKNLLEHEIIMIIDSLKFQTISN-KILFKEGENNDVIYLIDDGEVEI 717
RK E + + K+L E + I+D + + + + + +GE D Y+I+ GEV I
Sbjct: 215 RKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSI 274
Query: 718 I 720
+
Sbjct: 275 L 275
Score = 48.1 bits (113), Expect = 3e-05
Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 13/134 (9%)
Frame = +1
Query: 190 EQIKSSLKSIFLFEGLEENETNEMISFMSYXXXXXXXXXXXXNDPGDNFYVIEKGTFEAY 369
+ +S ++S+ LF+ LE +E +++ + + D+FY+IE G
Sbjct: 216 KMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSIL 275
Query: 370 KGGKLLKKYENSG-------------YFGELALLYNTPRNATVIATSDGQLWSLDRNSFQ 510
K K +N G YFGELAL+ N PR A+ A D + +D +F+
Sbjct: 276 IRSKT-KTNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFE 334
Query: 511 RHVLQHAFDKRKRS 552
R +L D KR+
Sbjct: 335 R-LLGPCMDIMKRN 347
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.135 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,588,897
Number of Sequences: 369166
Number of extensions: 1120366
Number of successful extensions: 3435
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3206
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3323
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)