Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02130
(730 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O61492|FLOT2_DROME Flotillin-2 163 5e-40
sp|Q98TZ8|FLT2_BRARE Flotillin-2a (Reggie-1a) (REG-1) 157 2e-38
sp|O42305|FLOT2_CARAU Flotillin-2 (Reggie-1) (REG-1) 156 5e-38
sp|Q60634|FLOT2_MOUSE Flotillin-2 (Epidermal surface antige... 155 1e-37
sp|Q14254|FLOT2_HUMAN Flotillin-2 (Epidermal surface antige... 155 1e-37
sp|Q9Z2S9|FLOT2_RAT Flotillin-2 (Reggie-1) (REG-1) 155 1e-37
sp|O61491|FLOT1_DROME Flotillin-1 138 2e-32
sp|Q7YR41|FLOT1_PANTR Flotillin-1 129 1e-29
sp|O08917|FLOT1_MOUSE Flotillin-1 129 1e-29
sp|Q9Z1E1|FLOT1_RAT Flotillin-1 (Reggie-2) (REG-2) 128 1e-29
>sp|O61492|FLOT2_DROME Flotillin-2
Length = 438
Score = 163 bits (412), Expect = 5e-40
Identities = 82/150 (54%), Positives = 119/150 (79%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
++EL GTVK PAEAEAF+ + LA A++ + + A+ EAE IR G AEA ++ VGKAEA
Sbjct: 292 DRELTGTVKLPAEAEAFRLQTLAQAKQCQTIEGARAEAERIRKIGSAEAHAIELVGKAEA 351
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVILGSGSDSKSDFTGEI 363
ERMR+KA Y +YGDAAI+++VL++LPK+AAE+AAPLAKT+EIV++G G+D + T ++
Sbjct: 352 ERMRMKAHVYKQYGDAAIMNIVLESLPKIAAEVAAPLAKTDEIVLIG-GND---NITNDV 407
Query: 364 TKLLGNLPPAVQAMTGVDISQAVRQIPGAR 453
T+L+ LPP++ A+TGVD+S+ + +IPGA+
Sbjct: 408 TRLVAQLPPSINALTGVDLSKVLSKIPGAK 437
>sp|Q98TZ8|FLT2_BRARE Flotillin-2a (Reggie-1a) (REG-1)
Length = 428
Score = 157 bits (398), Expect = 2e-38
Identities = 85/141 (60%), Positives = 110/141 (78%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
+KEL TV++PAEAEAFK E LA+A++ K+VL AQ EAE I+ G AEA S+ AVGKAEA
Sbjct: 279 DKELIATVRRPAEAEAFKMEQLAEAKKIKKVLTAQAEAEKIKRIGEAEAGSIEAVGKAEA 338
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVILGSGSDSKSDFTGEI 363
E+MRLKA AY +YG+AA +LVL+ALPK+A ++AAPL +TNEIVIL SG + TGE+
Sbjct: 339 EKMRLKAEAYQQYGEAAKTALVLEALPKIAGKVAAPLGRTNEIVIL-SGDGGR--VTGEV 395
Query: 364 TKLLGNLPPAVQAMTGVDISQ 426
+LL LP +V A+TGVD+S+
Sbjct: 396 NRLLAELPVSVNALTGVDLSK 416
>sp|O42305|FLOT2_CARAU Flotillin-2 (Reggie-1) (REG-1)
Length = 428
Score = 156 bits (395), Expect = 5e-38
Identities = 84/141 (59%), Positives = 112/141 (79%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
EKEL TVK+PAEAEA+K + LA+ ++ K+VL+AQ E+E IR G AEA S+S+VGKAEA
Sbjct: 279 EKELIATVKRPAEAEAYKMQQLAEGQKLKKVLIAQAESEKIRKIGEAEAISISSVGKAEA 338
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVILGSGSDSKSDFTGEI 363
E MRLKA AY +YG+AA +LVL+ALPK+A ++AAPLA+TNEIVIL SG S+ +GE+
Sbjct: 339 ESMRLKAEAYQQYGEAAKTALVLEALPKIAGKVAAPLARTNEIVIL-SGDGSR--VSGEV 395
Query: 364 TKLLGNLPPAVQAMTGVDISQ 426
+LL LP ++ A+TGVD+S+
Sbjct: 396 NRLLAELPVSINALTGVDLSK 416
>sp|Q60634|FLOT2_MOUSE Flotillin-2 (Epidermal surface antigen) (ESA)
Length = 379
Score = 155 bits (391), Expect = 1e-37
Identities = 85/153 (55%), Positives = 116/153 (75%), Gaps = 2/153 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
+KEL TV++PAEAEA + + +A+ + KQVLLAQ EAE IR G AEA+ + A+GKAEA
Sbjct: 230 DKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEA 289
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVILGSGSDSKSDFTGEI 363
ERM+LKA AY KYGDAA ++LVL+ALP++AA+I+APL K +EIV+L SG +SK T E+
Sbjct: 290 ERMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVL-SGDNSK--VTSEV 346
Query: 364 TKLLGNLPPAVQAMTGVDISQ--AVRQIPGARV 456
+LL LP +V A+TGVD+S+ ++ GA+V
Sbjct: 347 NRLLAELPASVHALTGVDLSKIPLIKNATGAQV 379
>sp|Q14254|FLOT2_HUMAN Flotillin-2 (Epidermal surface antigen) (ESA)
Length = 379
Score = 155 bits (391), Expect = 1e-37
Identities = 85/153 (55%), Positives = 116/153 (75%), Gaps = 2/153 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
+KEL TV++PAEAEA + + +A+ + KQVLLAQ EAE IR G AEA+ + A+GKAEA
Sbjct: 230 DKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEA 289
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVILGSGSDSKSDFTGEI 363
ERM+LKA AY KYGDAA ++LVL+ALP++AA+IAAPL K +EIV+L SG +SK T E+
Sbjct: 290 ERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVL-SGDNSK--VTSEV 346
Query: 364 TKLLGNLPPAVQAMTGVDISQ--AVRQIPGARV 456
+LL LP +V A+TGVD+S+ +++ G +V
Sbjct: 347 NRLLAELPASVHALTGVDLSKIPLIKKATGVQV 379
>sp|Q9Z2S9|FLOT2_RAT Flotillin-2 (Reggie-1) (REG-1)
Length = 428
Score = 155 bits (391), Expect = 1e-37
Identities = 85/153 (55%), Positives = 116/153 (75%), Gaps = 2/153 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
+KEL TV++PAEAEA + + +A+ + KQVLLAQ EAE IR G AEA+ + A+GKAEA
Sbjct: 279 DKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEA 338
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVILGSGSDSKSDFTGEI 363
ERM+LKA AY KYGDAA ++LVL+ALP++AA+I+APL K +EIV+L SG +SK T E+
Sbjct: 339 ERMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVL-SGDNSK--VTSEV 395
Query: 364 TKLLGNLPPAVQAMTGVDISQ--AVRQIPGARV 456
+LL LP +V A+TGVD+S+ ++ GA+V
Sbjct: 396 NRLLAELPASVHALTGVDLSKIPLIKNATGAQV 428
>sp|O61491|FLOT1_DROME Flotillin-1
Length = 426
Score = 138 bits (347), Expect = 2e-32
Identities = 68/145 (46%), Positives = 108/145 (74%), Gaps = 2/145 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
E+ELE T+++PAEAE F+ E LA+A + + V+ A+ EAE+IR+RG AEA +++A KAEA
Sbjct: 279 ERELEATIRRPAEAEKFRMEKLAEANKQRVVMEAEAEAESIRIRGEAEAFAIAAKAKAEA 338
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVIL--GSGSDSKSDFTG 357
E+M +KA AY +Y +AA++ ++LD LPKVAAE+AAPL++ +I ++ G+G + TG
Sbjct: 339 EQMAMKAEAYREYREAAMVEMLLDTLPKVAAEVAAPLSQAKKITMVSSGTGDIGAAKLTG 398
Query: 358 EITKLLGNLPPAVQAMTGVDISQAV 432
E+ ++ +P V+ +TGVDI+++V
Sbjct: 399 EVLSIVNKVPELVKNITGVDIARSV 423
>sp|Q7YR41|FLOT1_PANTR Flotillin-1
Length = 427
Score = 129 bits (323), Expect = 1e-29
Identities = 67/143 (46%), Positives = 100/143 (69%), Gaps = 2/143 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
EKELE V+KPAEAE +K E LA+A +++ ++ A+ EAE++R+RG AEA ++ A +AEA
Sbjct: 276 EKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAESVRMRGEAEAFAIGARARAEA 335
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVIL--GSGSDSKSDFTG 357
E+M KA A+ Y +AA L ++L+ LP+VA EI+ PL N+I ++ GSG+ + TG
Sbjct: 336 EQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTG 395
Query: 358 EITKLLGNLPPAVQAMTGVDISQ 426
E+ +L LP +V+ +TGV ISQ
Sbjct: 396 EVLDILTRLPESVERLTGVSISQ 418
>sp|O08917|FLOT1_MOUSE Flotillin-1
Length = 428
Score = 129 bits (323), Expect = 1e-29
Identities = 67/149 (44%), Positives = 100/149 (67%), Gaps = 2/149 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
EKELE V+KPAEAE ++ E LA+A + + ++ A+ EAE++R+RG AEA ++ A +AEA
Sbjct: 276 EKELEARVRKPAEAERYRLERLAEAEKAQLIMQAEAEAESVRMRGEAEAFAIGARARAEA 335
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVIL--GSGSDSKSDFTG 357
E+M KA A+ Y +AA L ++L+ LP+VA EI+ PL N+I ++ GSG+ + TG
Sbjct: 336 EQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTG 395
Query: 358 EITKLLGNLPPAVQAMTGVDISQAVRQIP 444
E+ +L LP +V+ +TGV ISQ P
Sbjct: 396 EVLDILSRLPESVERLTGVSISQVNHNKP 424
>sp|Q9Z1E1|FLOT1_RAT Flotillin-1 (Reggie-2) (REG-2)
Length = 428
Score = 128 bits (322), Expect = 1e-29
Identities = 67/149 (44%), Positives = 100/149 (67%), Gaps = 2/149 (1%)
Frame = +1
Query: 4 EKELEGTVKKPAEAEAFKTEILADARRTKQVLLAQGEAEAIRLRGHAEASSLSAVGKAEA 183
EKELE V+KPAEAE ++ E LA+A + + ++ A+ EAE++R+RG AEA ++ A +AEA
Sbjct: 276 EKELEARVRKPAEAERYRLERLAEAEKAQLIMQAEAEAESVRMRGEAEAFAVGARARAEA 335
Query: 184 ERMRLKAAAYNKYGDAAILSLVLDALPKVAAEIAAPLAKTNEIVIL--GSGSDSKSDFTG 357
E+M KA A+ Y +AA L ++L+ LP+VA EI+ PL N+I ++ GSG+ + TG
Sbjct: 336 EQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTG 395
Query: 358 EITKLLGNLPPAVQAMTGVDISQAVRQIP 444
E+ +L LP +V+ +TGV ISQ P
Sbjct: 396 EVLDILSRLPESVERLTGVSISQVNHNKP 424
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,071,039
Number of Sequences: 369166
Number of extensions: 1143845
Number of successful extensions: 3883
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3681
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3812
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6486082400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)