Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02117 (479 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9Y2K7|FXL11_HUMAN F-box/LRR-repeat protein 11 (F-box an... 42 0.001 sp|P59997|FXL11_MOUSE F-box/LRR-repeat protein 11 (F-box an... 41 0.002 sp|Q6P1G2|FXL10_MOUSE F-box/LRR-repeat protein 10 (F-box an... 40 0.002 sp|Q9UJT9|FBXL7_HUMAN F-box/LRR-repeat protein 7 (F-box and... 40 0.004 sp|Q9Z0Z3|SKP2_MOUSE S-phase kinase-associated protein 2 (F... 39 0.005 sp|Q8NHM5|FXL10_HUMAN F-box/LRR-repeat protein 10 (F-box an... 39 0.006 sp|Q8CDU4|FXL13_MOUSE F-box/LRR-repeat protein 13 (F-box an... 39 0.006 sp|Q6PB97|FXL19_MOUSE F-box/LRR-repeat protein 19 (F-box an... 38 0.014 sp|Q6PCT2|FXL19_HUMAN F-box/LRR-repeat protein 19 (F-box an... 38 0.014 sp|Q9UK96|FBX10_HUMAN F-box only protein 10 36 0.052
>sp|Q9Y2K7|FXL11_HUMAN F-box/LRR-repeat protein 11 (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) Length = 1162 Score = 41.6 bits (96), Expect = 0.001 Identities = 30/115 (26%), Positives = 47/115 (40%) Frame = +3 Query: 105 EIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQKKPK 284 E+W+ + YLS EL R C+ Y D +LW + L R + + I +++P Sbjct: 896 EVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPV 955 Query: 285 ELHFKNCFGTSITLNGLKEMFKICGQGVEKLSFISCSTGALEGDHFLLLSADFCP 449 L T+I+ L + G++ L CS A+ LS CP Sbjct: 956 SLDLS---WTNISKKQLTWLVNRL-PGLKDLLLAGCSWSAVSA-----LSTSSCP 1001
>sp|P59997|FXL11_MOUSE F-box/LRR-repeat protein 11 (F-box and leucine-rich repeat protein 11) Length = 560 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/115 (26%), Positives = 47/115 (40%) Frame = +3 Query: 105 EIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQKKPK 284 E+W+ + YLS EL R C+ Y D +LW + L R + + I +++P Sbjct: 294 EVWMSVFRYLSRKELCECIRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPV 353 Query: 285 ELHFKNCFGTSITLNGLKEMFKICGQGVEKLSFISCSTGALEGDHFLLLSADFCP 449 L T+I+ L + G++ L CS A+ LS CP Sbjct: 354 SLDLS---WTNISKKQLTWLVNRL-PGLKDLLLAGCSWSAVSA-----LSTSSCP 399
>sp|Q6P1G2|FXL10_MOUSE F-box/LRR-repeat protein 10 (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) Length = 1309 Score = 40.4 bits (93), Expect = 0.002 Identities = 19/62 (30%), Positives = 31/62 (50%) Frame = +3 Query: 105 EIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQKKPK 284 E+W+ + YLSH +L R CR D +LW + L R ++T + I +++P Sbjct: 1041 EVWMAVFSYLSHRDLCVCMRVCRTWNRWCCDKRLWTRIDLNRCKSITPLMLSGIIRRQPV 1100 Query: 285 EL 290 L Sbjct: 1101 SL 1102
>sp|Q9UJT9|FBXL7_HUMAN F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7) Length = 491 Score = 39.7 bits (91), Expect = 0.004 Identities = 28/133 (21%), Positives = 58/133 (43%), Gaps = 7/133 (5%) Frame = +3 Query: 96 LPAEIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQK 275 LP ++I +L ++L R R CRR Y++ D +LWR++ L + D + + ++ Sbjct: 117 LPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKVLTRR 176 Query: 276 KPKELHFKNCFGTSITLNGLKEM-------FKICGQGVEKLSFISCSTGALEGDHFLLLS 434 ++ ++T++G + + C + +L C + E + Sbjct: 177 LCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEA---VFDV 233 Query: 435 ADFCPNVTHINAS 473 CPN+ H++ S Sbjct: 234 VSLCPNLEHLDVS 246
>sp|Q9Z0Z3|SKP2_MOUSE S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1) Length = 424 Score = 39.3 bits (90), Expect = 0.005 Identities = 18/47 (38%), Positives = 26/47 (55%) Frame = +3 Query: 84 NWQCLPAEIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTL 224 +W LP E+ + I L EL R+ C+R Y + LD LW+S+ L Sbjct: 96 SWDSLPDELLLGIFSCLCLPELLRVSGVCKRWYRLSLDESLWQSLDL 142
>sp|Q8NHM5|FXL10_HUMAN F-box/LRR-repeat protein 10 (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (JEMMA protein) (CXXC finger protein 2) (Protein containing CXXC domain 2) Length = 1336 Score = 38.9 bits (89), Expect = 0.006 Identities = 18/62 (29%), Positives = 30/62 (48%) Frame = +3 Query: 105 EIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQKKPK 284 E+W+ + YLSH +L R CR D +LW + L ++T + I +++P Sbjct: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPV 1127 Query: 285 EL 290 L Sbjct: 1128 SL 1129
>sp|Q8CDU4|FXL13_MOUSE F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13) Length = 790 Score = 38.9 bits (89), Expect = 0.006 Identities = 29/139 (20%), Positives = 59/139 (42%), Gaps = 3/139 (2%) Frame = +3 Query: 66 NSNVASNWQCLPAEIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLT 245 N +A + LP + ++I +YL+ ++ R R ++ LW S+ N+ Sbjct: 233 NRRIAFDISVLPEQAILQIFLYLTFKDMMACSRVNRSWMAMIQRGSLWNSIDFSTVKNIA 292 Query: 246 DYHIINIAQK---KPKELHFKNCFGTSITLNGLKEMFKICGQGVEKLSFISCSTGALEGD 416 D ++ QK L+F+ C + TL + + +++L+ C + D Sbjct: 293 DKCVVTTLQKWRLNVLRLNFRGCDFRTKTLKAVSHC-----KNLQELNVSDCQSFT---D 344 Query: 417 HFLLLSADFCPNVTHINAS 473 + ++ CP V ++N S Sbjct: 345 ESMRHISEGCPGVLYLNLS 363
>sp|Q6PB97|FXL19_MOUSE F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19) Length = 674 Score = 37.7 bits (86), Expect = 0.014 Identities = 25/100 (25%), Positives = 44/100 (44%) Frame = +3 Query: 96 LPAEIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQK 275 LP W+++ +L EL R CR D +LW + L R +LT + + ++ Sbjct: 404 LPRAAWLRVFQHLGpreLCVCMRVCRTWSRWCYDKRLWPRMDLSRRKSLTPPMLSGVVRR 463 Query: 276 KPKELHFKNCFGTSITLNGLKEMFKICGQGVEKLSFISCS 395 +P+ L T ++ L + QG+++L CS Sbjct: 464 QPRALDLS---WTGVSKKQLMWLLNRL-QGLQELVLSGCS 499
>sp|Q6PCT2|FXL19_HUMAN F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19) Length = 674 Score = 37.7 bits (86), Expect = 0.014 Identities = 25/100 (25%), Positives = 44/100 (44%) Frame = +3 Query: 96 LPAEIWIKIMIYLSHSELSRLQRTCRRIYSIGLDSQLWRSVTLFRHSNLTDYHIINIAQK 275 LP W+++ +L EL R CR D +LW + L R +LT + + ++ Sbjct: 404 LPRAAWLRVFQHLGpreLCICMRVCRTWSRWCYDKRLWPRMDLSRRKSLTPPMLSGVVRR 463 Query: 276 KPKELHFKNCFGTSITLNGLKEMFKICGQGVEKLSFISCS 395 +P+ L T ++ L + QG+++L CS Sbjct: 464 QPRALDLS---WTGVSKKQLMWLLNRL-QGLQELVLSGCS 499
>sp|Q9UK96|FBX10_HUMAN F-box only protein 10 Length = 954 Score = 35.8 bits (81), Expect = 0.052 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 6/54 (11%) Frame = +3 Query: 96 LPAEIWIKIMIYLSHSELSRLQRTCRRIYS--IGLDSQLWRSVTL----FRHSN 239 LP E+W I+ YL +L R CR Y + LDS WR + L RH N Sbjct: 6 LPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPN 59
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 55,699,637 Number of Sequences: 369166 Number of extensions: 1045905 Number of successful extensions: 2671 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2599 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2671 length of database: 68,354,980 effective HSP length: 102 effective length of database: 49,512,010 effective search space used: 2822184570 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)