Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02108
(770 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P98195|ATP9B_MOUSE Probable phospholipid-transporting AT... 370 e-102
sp|O43861|ATP9B_HUMAN Probable phospholipid-transporting AT... 369 e-102
sp|O75110|ATP9A_HUMAN Probable phospholipid-transporting AT... 355 8e-98
sp|O70228|ATP9A_MOUSE Probable phospholipid-transporting AT... 351 1e-96
sp|Q10309|YD56_SCHPO Putative phospholipid-transporting ATP... 263 4e-70
sp|P40527|ATC7_YEAST Probable phospholipid-transporting ATP... 262 9e-70
sp|Q8K2X1|AT10D_MOUSE Probable phospholipid-transporting AT... 190 3e-48
sp|Q9GKS6|AT10D_MACFA Probable phospholipid-transporting AT... 188 2e-47
sp|P70704|AT8A1_MOUSE Probable phospholipid-transporting AT... 187 4e-47
sp|P98205|ALA2_ARATH Putative phospholipid-transporting ATP... 183 4e-46
>sp|P98195|ATP9B_MOUSE Probable phospholipid-transporting ATPase IIB
Length = 1095
Score = 370 bits (949), Expect = e-102
Identities = 182/254 (71%), Positives = 211/254 (83%)
Frame = +1
Query: 4 GNMAREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCL 183
GNMAREGLRTLVV K+ LTEEQY DFESRY QAK+SI DRA KVAA + ++ER+++LLCL
Sbjct: 626 GNMAREGLRTLVVAKRTLTEEQYQDFESRYSQAKLSIHDRALKVAAVVESLEREMELLCL 685
Query: 184 TGVEDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPVAG 363
TGVED+LQ VRPTLE LRNAGI++WMLTGDKLETA IAKSS LVSR Q +H+F+PV
Sbjct: 686 TGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHVFRPVTS 745
Query: 364 RAEAHLELNAFRKRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQKADI 543
R EAHLELNAFR++ D ALVI+G SL+ CL +YE+E ++LA QCPAVV CRCSPTQKA I
Sbjct: 746 RGEAHLELNAFRRKHDCALVISGDSLEVCLRYYEHELVELACQCPAVVCCRCSPTQKAHI 805
Query: 544 VRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHVARLF 723
V LLR HT R AIGDGGNDVSMI AAD GIGI GKEG+QASLA+DFS+ QF H+ RL
Sbjct: 806 VTLLRQHTRKRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLL 865
Query: 724 LVHGRNTYKNTATL 765
+VHGRN+YK +A L
Sbjct: 866 MVHGRNSYKRSAAL 879
>sp|O43861|ATP9B_HUMAN Probable phospholipid-transporting ATPase IIB
Length = 1095
Score = 369 bits (948), Expect = e-102
Identities = 182/254 (71%), Positives = 213/254 (83%)
Frame = +1
Query: 4 GNMAREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCL 183
GNMAREGLRTLVV KK LTEEQY DFESRY QAK+S+ DR+ KVAA + ++ER+++LLCL
Sbjct: 626 GNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCL 685
Query: 184 TGVEDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPVAG 363
TGVED+LQ VRPTLE LRNAGI++WMLTGDKLETA IAKSS LVSR Q +HIF+ V
Sbjct: 686 TGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTS 745
Query: 364 RAEAHLELNAFRKRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQKADI 543
R EAHLELNAFR++ D ALVI+G SL+ CL++YE+EF++LA QCPAVV CRCSPTQKA I
Sbjct: 746 RGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARI 805
Query: 544 VRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHVARLF 723
V LL+ HTG R AIGDGGNDVSMI AAD GIGI GKEG+QASLA+DFS+ QF H+ RL
Sbjct: 806 VTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLL 865
Query: 724 LVHGRNTYKNTATL 765
+VHGRN+YK +A L
Sbjct: 866 MVHGRNSYKRSAAL 879
>sp|O75110|ATP9A_HUMAN Probable phospholipid-transporting ATPase IIA (ATPase class II type
9A) (ATPase IIA)
Length = 1047
Score = 355 bits (911), Expect = 8e-98
Identities = 171/255 (67%), Positives = 209/255 (81%)
Frame = +1
Query: 4 GNMAREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCL 183
GNMAREGLR LVV KK L EEQY DFE+RY QAK+S+ DR+ KVA + ++E +++LLCL
Sbjct: 589 GNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCL 648
Query: 184 TGVEDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPVAG 363
TGVED+LQ VRPTLETLRNAGI+VWMLTGDKLETA AK++ LV+RNQ +H+F+ V
Sbjct: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTN 708
Query: 364 RAEAHLELNAFRKRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQKADI 543
R EAHLELNAFR++ D ALVI+G SL+ CL++YEYEFM+LA QCPAVV CRC+PTQKA I
Sbjct: 709 RGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQI 768
Query: 544 VRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHVARLF 723
VRLL+ TG A+GDGGNDVSMI +D G+G+ GKEG+QASLA+DFS+ QF H+ RL
Sbjct: 769 VRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLL 828
Query: 724 LVHGRNTYKNTATLS 768
+VHGRN+YK +A LS
Sbjct: 829 MVHGRNSYKRSAALS 843
>sp|O70228|ATP9A_MOUSE Probable phospholipid-transporting ATPase IIA (ATPase class II type
9A)
Length = 1047
Score = 351 bits (901), Expect = 1e-96
Identities = 170/255 (66%), Positives = 208/255 (81%)
Frame = +1
Query: 4 GNMAREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCL 183
GNMAREGLR LVV KK LTEEQY FE+RY QAK+S+ DR+ KVA + ++E +++LLCL
Sbjct: 589 GNMAREGLRVLVVAKKSLTEEQYQHFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCL 648
Query: 184 TGVEDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPVAG 363
TGVED+LQ VRPTLETLRNAGI+VWMLTGDKLETA AK++ LV+RNQ +H+F+ V
Sbjct: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTN 708
Query: 364 RAEAHLELNAFRKRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQKADI 543
R EAHLELNAFR++ D ALVI+G SL+ CL++YEYEFM+LA QCPAVV CRC+PTQKA I
Sbjct: 709 RGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQI 768
Query: 544 VRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHVARLF 723
VRLL+ TG A+ DGGNDVSMI +D G+G+ GKEG+QASLA+DFS+ QF H+ RL
Sbjct: 769 VRLLQERTGKLTCAVWDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLL 828
Query: 724 LVHGRNTYKNTATLS 768
+VHGRN+YK +A LS
Sbjct: 829 MVHGRNSYKRSAALS 843
>sp|Q10309|YD56_SCHPO Putative phospholipid-transporting ATPase C6C3.06c
Length = 1033
Score = 263 bits (672), Expect = 4e-70
Identities = 135/257 (52%), Positives = 181/257 (70%), Gaps = 2/257 (0%)
Frame = +1
Query: 4 GNMAREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLAT--IERDLDLL 177
GN+AREGLRTLVV KK L+ E+Y F + A +S ++ K + + +E D+DLL
Sbjct: 572 GNLAREGLRTLVVAKKDLSAEEYSAFSLAHSDASLSFSNSRDKKMEEIVSRYLENDMDLL 631
Query: 178 CLTGVEDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPV 357
LTGVEDKLQ+ V+ TLE LRNAGI VWMLTGDK+ETA IA SSRLVSR Q +H +
Sbjct: 632 GLTGVEDKLQKDVKITLELLRNAGIHVWMLTGDKVETARCIAISSRLVSRGQYIHTINQL 691
Query: 358 AGRAEAHLELNAFRKRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQKA 537
+ R EAH L R + DS L+I G+S++ C+ + + EF+ + +VV+CRC+PTQKA
Sbjct: 692 SSREEAHNHLLTLRNKPDSCLIIDGESMEFCIGYLQNEFIDIVSDLSSVVICRCTPTQKA 751
Query: 538 DIVRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHVAR 717
++ RL++ + IGDGGNDV MI A+VGIGIVGKEG+QASLA+D+S+ +F+HV+R
Sbjct: 752 NMTRLIQEKKQASVCCIGDGGNDVGMIQVANVGIGIVGKEGQQASLAADYSVKEFSHVSR 811
Query: 718 LFLVHGRNTYKNTATLS 768
L L HGR +YK T+ L+
Sbjct: 812 LLLWHGRISYKQTSKLA 828
>sp|P40527|ATC7_YEAST Probable phospholipid-transporting ATPase NEO1
Length = 1151
Score = 262 bits (669), Expect = 9e-70
Identities = 130/257 (50%), Positives = 181/257 (70%), Gaps = 1/257 (0%)
Frame = +1
Query: 1 TGNMAREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLAT-IERDLDLL 177
TGNMAREGLRTLV+G+K L ++ Y F+ Y+ A +S+ +R +++ + +E DL+LL
Sbjct: 684 TGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELL 743
Query: 178 CLTGVEDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPV 357
LTGVEDKLQ+ V+ ++E LRNAGI++WMLTGDK+ETA ++ S++L+SR Q +H V
Sbjct: 744 GLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKV 803
Query: 358 AGRAEAHLELNAFRKRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQKA 537
A +L + ++ L+I G+SL L+ YE EF + + P V+ CRC+P QKA
Sbjct: 804 TRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKA 863
Query: 538 DIVRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHVAR 717
D+ ++R TG R+ IGDGGNDVSMI ADVG+GIVGKEG+QASLA+DFS+ QF H+
Sbjct: 864 DVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTE 923
Query: 718 LFLVHGRNTYKNTATLS 768
L L HGRN+YK +A L+
Sbjct: 924 LLLWHGRNSYKRSAKLA 940
>sp|Q8K2X1|AT10D_MOUSE Probable phospholipid-transporting ATPase VD (ATPVD)
Length = 1416
Score = 190 bits (483), Expect = 3e-48
Identities = 110/278 (39%), Positives = 164/278 (58%), Gaps = 27/278 (9%)
Frame = +1
Query: 13 AREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCLTGV 192
A+ GLRTL V KKV+++ +Y ++ + A+ SI +R + + +E L LL TG+
Sbjct: 833 AKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGI 892
Query: 193 EDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIF-------- 348
ED+LQE V ++E L AGI++WMLTGDK ETA +IA + +L+ + L I
Sbjct: 893 EDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDAC 952
Query: 349 --------QPVAGRAEAHLELNAFRKR----SDS------ALVITGQSLQTCL-EFYEYE 471
+ + RA+ EL + RK SD+ LVITG++L+ L E + +
Sbjct: 953 GMLMSAILEELQKRAQVSPELASSRKNFPQPSDAQGQGRAGLVITGKTLEFALQESLQRQ 1012
Query: 472 FMQLAIQCPAVVVCRCSPTQKADIVRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVG 651
F++L C AV+ CR +P QK+++V+L+R H IGDG NDVSMI AD+GIG+ G
Sbjct: 1013 FLELTAWCQAVICCRATPLQKSEVVKLVRNHHHVLTLPIGDGANDVSMIQVADIGIGVSG 1072
Query: 652 KEGRQASLASDFSLVQFNHVARLFLVHGRNTYKNTATL 765
+EG QA +ASDF++ QF H+++L LVHG Y + +
Sbjct: 1073 QEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNM 1110
>sp|Q9GKS6|AT10D_MACFA Probable phospholipid-transporting ATPase VD
Length = 653
Score = 188 bits (477), Expect = 2e-47
Identities = 104/258 (40%), Positives = 160/258 (62%), Gaps = 7/258 (2%)
Frame = +1
Query: 13 AREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCLTGV 192
A++GLRTL + KKV+++ +Y ++ + A+ SI +R + + +E L LL TG+
Sbjct: 119 AKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGI 178
Query: 193 EDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSR--NQSLHIFQPVAGR 366
ED+LQE V ++E L AGI++WMLTGDK ETA +IA + L+S + Q + +
Sbjct: 179 EDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACMLMSTILKELQKKTQALPEQ 238
Query: 367 AEAHLELNAFRKRSDSAL----VITGQSLQTCL-EFYEYEFMQLAIQCPAVVVCRCSPTQ 531
++L+ DS L +ITG++L+ L E + +F++L C VV CR +P Q
Sbjct: 239 VSLSVDLHQPPVPQDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQTVVCCRATPLQ 298
Query: 532 KADIVRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHV 711
K+++V+L+R+H AIGDG NDVSMI AD+GIG+ G+EG QA +ASDF++ QF H+
Sbjct: 299 KSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHL 358
Query: 712 ARLFLVHGRNTYKNTATL 765
++L LVHG Y + +
Sbjct: 359 SKLLLVHGHWCYTRLSNM 376
>sp|P70704|AT8A1_MOUSE Probable phospholipid-transporting ATPase IA (Chromaffin granule
ATPase II) (ATPase class I type 8A member 1)
Length = 1149
Score = 187 bits (474), Expect = 4e-47
Identities = 104/259 (40%), Positives = 152/259 (58%), Gaps = 10/259 (3%)
Frame = +1
Query: 13 AREGLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCLTGV 192
A EGLRTL ++E + ++ + YH+A S+ +R K+ + IE++L LL T +
Sbjct: 585 ATEGLRTLCFAVAEISESDFEEWRAVYHRASTSVQNRLLKLEESYELIEKNLQLLGATAI 644
Query: 193 EDKLQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPVAGRAE 372
EDKLQ+ V T+ETL A I++W+LTGDK ETA +I S RL+ RN + + G +
Sbjct: 645 EDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCRLLKRNMGMIVINE--GSLD 702
Query: 373 AHLEL---------NAFRKRSDSALVITGQSLQTCLEF-YEYEFMQLAIQCPAVVVCRCS 522
E +A RK +D AL+I G++L+ L F F+ LA+ C AV+ CR S
Sbjct: 703 GTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVS 762
Query: 523 PTQKADIVRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQF 702
P QK+++V +++ AIGDG NDVSMI A VG+GI G EG QA+ +SD+S+ QF
Sbjct: 763 PLQKSEVVEMVKKQVKVITLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQF 822
Query: 703 NHVARLFLVHGRNTYKNTA 759
++ L +VHG Y +
Sbjct: 823 KYLKNLLMVHGAWNYNRVS 841
>sp|P98205|ALA2_ARATH Putative phospholipid-transporting ATPase 2 (Aminophospholipid
flippase 2)
Length = 1107
Score = 183 bits (465), Expect = 4e-46
Identities = 104/259 (40%), Positives = 153/259 (59%), Gaps = 10/259 (3%)
Frame = +1
Query: 22 GLRTLVVGKKVLTEEQYLDFESRYHQAKMSITDRAAKVAATLATIERDLDLLCLTGVEDK 201
GLRTL + + L E +YL++ ++ +A + DR ++A +E DL +L +T +ED+
Sbjct: 554 GLRTLCLAWRELEENEYLEWSVKFKEASSLLVDREWRIAEVCQRLEHDLYILGVTAIEDR 613
Query: 202 LQESVRPTLETLRNAGIRVWMLTGDKLETAESIAKSSRLVSRNQSLHIFQPVAGRAEAHL 381
LQ+ V T+ETLR AGI WMLTGDK TA IA S +S + + G+ E +
Sbjct: 614 LQDGVPETIETLRKAGINFWMLTGDKQNTAIQIALSCNFISPEPKGQLLM-IDGKTEEDV 672
Query: 382 ELNAFR----------KRSDSALVITGQSLQTCLEFYEYEFMQLAIQCPAVVVCRCSPTQ 531
+ R + D A VI G +L+ L+ + +F++LAI + CR +P+Q
Sbjct: 673 SRSLERVLLTMRITASEPKDVAFVIDGWALEIALKHHRKDFVELAILSRTAICCRVTPSQ 732
Query: 532 KADIVRLLRTHTGCRIAAIGDGGNDVSMILAADVGIGIVGKEGRQASLASDFSLVQFNHV 711
KA +V +L++ R AIGDGGNDV MI AD+G+GI G+EG QA+ A+D+S+ +F +
Sbjct: 733 KAQLVEILKS-CDYRTLAIGDGGNDVRMIQQADIGVGISGREGLQAARAADYSIGRFRFL 791
Query: 712 ARLFLVHGRNTYKNTATLS 768
RL LVHGR +Y TA LS
Sbjct: 792 KRLILVHGRYSYNRTAFLS 810
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,752,821
Number of Sequences: 369166
Number of extensions: 1521060
Number of successful extensions: 5078
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4655
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4949
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7163732800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)