Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02097
(179 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O95466|FMNL_HUMAN Formin-like 1 protein (Formin-like pro... 38 0.006
sp|O88874|CCNK_MOUSE Cyclin-K 37 0.011
sp|P48608|DIA_DROME Diaphanous protein 36 0.024
sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protei... 36 0.031
sp|P21997|SSGP_VOLCA Sulfated surface glycoprotein 185 prec... 36 0.031
sp|Q91YD9|WASL_MOUSE Neural Wiskott-Aldrich syndrome protei... 36 0.031
sp|Q95107|WASL_BOVIN Neural Wiskott-Aldrich syndrome protei... 36 0.031
sp|O08816|WASL_RAT Neural Wiskott-Aldrich syndrome protein ... 36 0.031
sp|Q96RN5|PCQAP_HUMAN Positive cofactor 2 glutamine/Q-rich-... 35 0.041
sp|Q01956|KCNC3_RAT Potassium voltage-gated channel subfami... 35 0.053
>sp|O95466|FMNL_HUMAN Formin-like 1 protein (Formin-like protein) (Leukocyte formin)
(CLL-associated antigen KW-13)
Length = 1100
Score = 38.1 bits (87), Expect = 0.006
Identities = 24/51 (47%), Positives = 30/51 (58%), Gaps = 6/51 (11%)
Frame = -3
Query: 135 GECPSPLKVG*PQGFPSPDVV---KPRPGSAPHPPPYRANGGPAP---PPS 1
G+ P+P G P G PSPD+ +P PG+AP PPP G P+P PPS
Sbjct: 514 GDAPTP---GVPTGSPSPDLAPAAEPAPGAAPPPPP-PLPGLPSPQEAPPS 560
Score = 32.0 bits (71), Expect = 0.45
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = -3
Query: 123 SPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
+P G P+ P+P + P P PPP GP PPP
Sbjct: 565 APPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPP 604
>sp|O88874|CCNK_MOUSE Cyclin-K
Length = 554
Score = 37.4 bits (85), Expect = 0.011
Identities = 15/32 (46%), Positives = 16/32 (50%)
Frame = -3
Query: 102 PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPP 7
P FP P + P PG P PP Y N P PP
Sbjct: 465 PASFPPPTIPPPTPGYPPPPPTYNPNFPPPPP 496
>sp|P48608|DIA_DROME Diaphanous protein
Length = 1091
Score = 36.2 bits (82), Expect = 0.024
Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPGSA---PHPPPYRANGGPAPPP 4
P P G G P P P PG A P PPP GGP PPP
Sbjct: 527 PPPPMPGRAGGGPPPPPPPPMPGRAGGPPPPPPPPGMGGPPPPP 570
Score = 33.1 bits (74), Expect = 0.20
Identities = 18/41 (43%), Positives = 20/41 (48%), Gaps = 8/41 (19%)
Frame = -3
Query: 102 PQGFPSPDVVKPRP----GSAPHPPPY----RANGGPAPPP 4
P P ++ P P G AP PPP RA GGP PPP
Sbjct: 503 PNKLPKVNIPMPPPPPGGGGAPPPPPPPMPGRAGGGPPPPP 543
Score = 31.6 bits (70), Expect = 0.59
Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 5/62 (8%)
Frame = -3
Query: 174 IAQPSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPP-----PYRANGGPAP 10
+A PS + P P G P P + R G P PP P RA G P P
Sbjct: 498 VAAPSPNKLPKVNIPMPPPPPGGGGAPPPPPPPMPGRAGGGPPPPPPPPMPGRAGGPPPP 557
Query: 9 PP 4
PP
Sbjct: 558 PP 559
>sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protein (N-WASP)
Length = 505
Score = 35.8 bits (81), Expect = 0.031
Identities = 20/48 (41%), Positives = 21/48 (43%)
Frame = -3
Query: 144 RRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPPS 1
RR+ P P G P P P S P PPP R G P PPPS
Sbjct: 273 RRQAPPPPPPSRGGP-----PPPPPPPHNSGPPPPPARGRGAPPPPPS 315
Score = 30.0 bits (66), Expect = 1.7
Identities = 17/41 (41%), Positives = 19/41 (46%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
PS G P P P V+ P + P PPP GP PPP
Sbjct: 351 PSSAPSGPPP--PPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389
Score = 28.9 bits (63), Expect = 3.8
Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 5/46 (10%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPG-----SAPHPPPYRANGGPAPPP 4
P P + G P P P P P AP PPP RA PPP
Sbjct: 280 PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP 325
>sp|P21997|SSGP_VOLCA Sulfated surface glycoprotein 185 precursor (SSG 185)
Length = 485
Score = 35.8 bits (81), Expect = 0.031
Identities = 20/54 (37%), Positives = 21/54 (38%)
Frame = -3
Query: 165 PSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
P A+ R PSP P PSP P P P PPP P PPP
Sbjct: 233 PQPTASSRPPSPPPSPRPPSPPPPSPSPPPPPPPPPPPPPPPPPSPPPPPPPPP 286
Score = 30.8 bits (68), Expect = 1.0
Identities = 19/56 (33%), Positives = 21/56 (37%)
Frame = -3
Query: 171 AQPSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
++P S R P P P P P P P S P PPP P PPP
Sbjct: 239 SRPPSPPPSPRPPSPPPPSPSPPPPPPPPPPPPPPPPPSPPPPPPPPPPPPPPPPP 294
Score = 29.6 bits (65), Expect = 2.2
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 5/39 (12%)
Frame = -3
Query: 102 PQGFPSPDV--VKPRPGSAPHPP---PYRANGGPAPPPS 1
P G P+V + P P ++P PP P ++ P+PPPS
Sbjct: 209 PTGLSGPNVNPIGPAPNNSPLPPSPQPTASSRPPSPPPS 247
Score = 28.5 bits (62), Expect = 5.0
Identities = 16/42 (38%), Positives = 17/42 (40%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPPS 1
P P P PSP P P P PPP + P PPS
Sbjct: 264 PPPPPPPPPPPPPSPPPPPPPPPPPPPPPPPPSPSPPRKPPS 305
Score = 28.1 bits (61), Expect = 6.5
Identities = 17/58 (29%), Positives = 20/58 (34%)
Frame = -3
Query: 177 PIAQPSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
P QP++ + P P P P P P P P PP P PPP
Sbjct: 231 PSPQPTASSRPPSPPPSPRPPSPPPPSPSPPPPPPPPPPPPPPPPPSPPPPPPPPPPP 288
>sp|Q91YD9|WASL_MOUSE Neural Wiskott-Aldrich syndrome protein (N-WASP)
Length = 501
Score = 35.8 bits (81), Expect = 0.031
Identities = 20/48 (41%), Positives = 21/48 (43%)
Frame = -3
Query: 144 RRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPPS 1
RR+ P P G P P P S P PPP R G P PPPS
Sbjct: 270 RRQAPPPPPPSRGGP-----PPPPPPPHSSGPPPPPARGRGAPPPPPS 312
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 5/46 (10%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPG-----SAPHPPPYRANGGPAPPP 4
P P + G P P P P P AP PPP RA PPP
Sbjct: 277 PPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPP 322
Score = 28.9 bits (63), Expect = 3.8
Identities = 12/29 (41%), Positives = 13/29 (44%)
Frame = -3
Query: 90 PSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
P P + P P PPP G APPP
Sbjct: 343 PPPALPSSAPSGPPPPPPPSMAGSTAPPP 371
>sp|Q95107|WASL_BOVIN Neural Wiskott-Aldrich syndrome protein (N-WASP)
Length = 505
Score = 35.8 bits (81), Expect = 0.031
Identities = 20/48 (41%), Positives = 21/48 (43%)
Frame = -3
Query: 144 RRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPPS 1
RR+ P P G P P P S P PPP R G P PPPS
Sbjct: 273 RRQAPPPPPPSRGGP-----PPPPPPPHSSGPPPPPARGRGAPPPPPS 315
Score = 30.0 bits (66), Expect = 1.7
Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Frame = -3
Query: 177 PIAQPSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRP----------GSAPHPPPYRA 28
P PS T PS VG P P P+ + P P G P PPP
Sbjct: 310 PPPPPSRAPTAAPPPPPPSRPGVGAPP--PPPNRMYPPPLPALPSSAPSGPPPPPPPLSV 367
Query: 27 NGGPAPPP 4
+G APPP
Sbjct: 368 SGSVAPPP 375
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 5/46 (10%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPG-----SAPHPPPYRANGGPAPPP 4
P P + G P P P P P AP PPP RA PPP
Sbjct: 280 PPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPP 325
Score = 28.1 bits (61), Expect = 6.5
Identities = 13/34 (38%), Positives = 17/34 (50%), Gaps = 1/34 (2%)
Frame = -3
Query: 99 QGFPSPDVVKPRPGSAPHPPPYRAN-GGPAPPPS 1
+G P P + + P PPP R G P PPP+
Sbjct: 307 RGAPPPPPSRAPTAAPPPPPPSRPGVGAPPPPPN 340
>sp|O08816|WASL_RAT Neural Wiskott-Aldrich syndrome protein (N-WASP)
Length = 501
Score = 35.8 bits (81), Expect = 0.031
Identities = 20/48 (41%), Positives = 21/48 (43%)
Frame = -3
Query: 144 RRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPPS 1
RR+ P P G P P P S P PPP R G P PPPS
Sbjct: 270 RRQAPPPPPPSRGGP-----PPPPPPPHSSGPPPPPARGRGAPPPPPS 312
Score = 29.6 bits (65), Expect = 2.2
Identities = 12/29 (41%), Positives = 13/29 (44%)
Frame = -3
Query: 90 PSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
P P + P P PPP G APPP
Sbjct: 343 PPPALPSSAPSGPPPPPPLSMAGSTAPPP 371
Score = 29.3 bits (64), Expect = 2.9
Identities = 18/46 (39%), Positives = 19/46 (41%), Gaps = 5/46 (10%)
Frame = -3
Query: 126 PSPLKVG*PQGFPSPDVVKPRPG-----SAPHPPPYRANGGPAPPP 4
P P + G P P P P P AP PPP RA PPP
Sbjct: 277 PPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPP 322
>sp|Q96RN5|PCQAP_HUMAN Positive cofactor 2 glutamine/Q-rich-associated protein (PC2
glutamine/Q-rich-associated protein) (TPA-inducible gene
1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa
component) (ARC105) (CTG repeat protein 7a)
Length = 788
Score = 35.4 bits (80), Expect = 0.041
Identities = 20/59 (33%), Positives = 25/59 (42%)
Frame = -3
Query: 177 PIAQPSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPPS 1
P+AQ S + P +V PQ P P P+PG P + GPAP PS
Sbjct: 421 PMAQVSQSSLPMLSSPSPGQ-QVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPS 478
>sp|Q01956|KCNC3_RAT Potassium voltage-gated channel subfamily C member 3 (Voltage-gated
potassium channel subunit Kv3.3) (KSHIIID)
Length = 889
Score = 35.0 bits (79), Expect = 0.053
Identities = 17/57 (29%), Positives = 27/57 (47%)
Frame = -3
Query: 174 IAQPSSRATQRRKGECPSPLKVG*PQGFPSPDVVKPRPGSAPHPPPYRANGGPAPPP 4
+A + +++ P P + G SP+ KP P P P P+ +GG +PPP
Sbjct: 549 LAMAKQKLPKKKNKHIPRPPQPG------SPNYCKPDPPPPPPPHPHHGSGGISPPP 599
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,826,321
Number of Sequences: 369166
Number of extensions: 649567
Number of successful extensions: 7151
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3561
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5942
length of database: 68,354,980
effective HSP length: 32
effective length of database: 62,443,460
effective search space used: 1685973420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)