Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02042 (789 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P52031|G6PI_DROYA Glucose-6-phosphate isomerase (GPI) (P... 249 6e-66 sp|P52029|G6PI_DROME Glucose-6-phosphate isomerase (GPI) (P... 248 1e-65 sp|P52030|G6PI_DROSI Glucose-6-phosphate isomerase (GPI) (P... 248 1e-65 sp|P50309|G6PI_CRIGR Glucose-6-phosphate isomerase (GPI) (P... 243 3e-64 sp|P06745|G6PI_MOUSE Glucose-6-phosphate isomerase (GPI) (P... 243 3e-64 sp|Q5R4E3|G6PI_PONPY Glucose-6-phosphate isomerase (GPI) (P... 243 3e-64 sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase (GPI) (P... 243 4e-64 sp|Q9N1E2|G6PI_RABIT Glucose-6-phosphate isomerase (GPI) (P... 241 2e-63 sp|P08059|G6PI_PIG Glucose-6-phosphate isomerase (GPI) (Pho... 239 8e-63 sp|Q664W9|G6PI_YERPS Glucose-6-phosphate isomerase (GPI) (P... 226 4e-59
>sp|P52031|G6PI_DROYA Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 249 bits (636), Expect = 6e-66 Identities = 120/178 (67%), Positives = 135/178 (75%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSI L IG E NFE LL G H MD HF+ TPL Sbjct: 273 WVGGRYSLWSAIGLSICLSIGFE----------------NFEQLLDGAHYMDNHFRTTPL 316 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PVI+A+LG+ Y + +KAETH +LPYDQY+HRF+AYFQQGDMESNGK V+ GK V Sbjct: 317 EKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKAGKAVK 376 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEVESSDQL 45 YSTGPI+WGEPGTNGQHAFYQLIHQGTRLIPCDF+ PAQTHNPI G HH++ S+ L Sbjct: 377 YSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFL 434
Score = 50.8 bits (120), Expect = 4e-06 Identities = 23/31 (74%), Positives = 25/31 (80%) Frame = -3 Query: 727 AVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +V+KHFVALSTN KV EFGID NMF FWD Sbjct: 242 SVAKHFVALSTNKEKVTEFGIDSTNMFGFWD 272
>sp|P52029|G6PI_DROME Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 248 bits (633), Expect = 1e-65 Identities = 120/178 (67%), Positives = 134/178 (75%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSI L IG E NFE LL G H MD HFK TP Sbjct: 273 WVGGRYSLWSAIGLSICLSIGFE----------------NFEQLLDGAHFMDNHFKTTPF 316 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PVI+A+LG+ Y + +KAETH +LPYDQY+HRF+AYFQQGDMESNGK V+ GK V Sbjct: 317 EKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVK 376 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEVESSDQL 45 YSTGPI+WGEPGTNGQHAFYQLIHQGTRLIPCDF+ PAQTHNPI G HH++ S+ L Sbjct: 377 YSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFL 434
Score = 50.8 bits (120), Expect = 4e-06 Identities = 23/31 (74%), Positives = 25/31 (80%) Frame = -3 Query: 727 AVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +V+KHFVALSTN KV EFGID NMF FWD Sbjct: 242 SVAKHFVALSTNKEKVTEFGIDSTNMFGFWD 272
>sp|P52030|G6PI_DROSI Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 248 bits (633), Expect = 1e-65 Identities = 120/178 (67%), Positives = 134/178 (75%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSI L IG E NFE LL G H MD HFK TP Sbjct: 273 WVGGRYSLWSAIGLSICLSIGFE----------------NFEQLLDGAHFMDNHFKTTPF 316 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PVI+A+LG+ Y + +KAETH +LPYDQY+HRF+AYFQQGDMESNGK V+ GK V Sbjct: 317 EKNAPVILALLGVWYSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVK 376 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEVESSDQL 45 YSTGPI+WGEPGTNGQHAFYQLIHQGTRLIPCDF+ PAQTHNPI G HH++ S+ L Sbjct: 377 YSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFL 434
Score = 50.8 bits (120), Expect = 4e-06 Identities = 23/31 (74%), Positives = 25/31 (80%) Frame = -3 Query: 727 AVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +V+KHFVALSTN KV EFGID NMF FWD Sbjct: 242 SVAKHFVALSTNKEKVTEFGIDSTNMFGFWD 272
>sp|P50309|G6PI_CRIGR Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 243 bits (621), Expect = 3e-64 Identities = 112/172 (65%), Positives = 132/172 (76%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL+IG +NFE LL+G H MD HF++TPL Sbjct: 269 WVGGRYSLWSAIGLSIALHIG----------------FDNFEQLLSGAHWMDQHFRKTPL 312 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PV++A+LGI Y++ Y ETH +LPYDQYMHRF+AYFQQGDMESNGK + G V Sbjct: 313 EKNAPVLLALLGIWYINFYGCETHALLPYDQYMHRFAAYFQQGDMESNGKSITRSGTRVD 372 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEV 63 + TGPI+WGEPGTNGQHAFYQLIHQGT++IPCDFLIP QT +PI GLHH++ Sbjct: 373 HHTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKI 424
Score = 56.6 bits (135), Expect = 8e-08 Identities = 24/32 (75%), Positives = 28/32 (87%) Frame = -3 Query: 730 NAVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 + V+KHF+ALSTN KVKEFGID +NMFEFWD Sbjct: 237 STVAKHFIALSTNTSKVKEFGIDPQNMFEFWD 268
>sp|P06745|G6PI_MOUSE Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Neuroleukin) (NLK) Length = 558 Score = 243 bits (621), Expect = 3e-64 Identities = 111/172 (64%), Positives = 132/172 (76%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL++G ++FE LL+G H MD HF +TPL Sbjct: 269 WVGGRYSLWSAIGLSIALHVG----------------FDHFEQLLSGAHWMDQHFLKTPL 312 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PV++A+LGI Y++CY ETH +LPYDQYMHRF+AYFQQGDMESNGK + G V Sbjct: 313 EKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVD 372 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEV 63 + TGPI+WGEPGTNGQHAFYQLIHQGT++IPCDFLIP QT +PI GLHH++ Sbjct: 373 HQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKI 424
Score = 58.5 bits (140), Expect = 2e-08 Identities = 26/32 (81%), Positives = 29/32 (90%) Frame = -3 Query: 730 NAVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +AV+KHFVALSTN KVKEFGID +NMFEFWD Sbjct: 237 SAVAKHFVALSTNTAKVKEFGIDPQNMFEFWD 268
>sp|Q5R4E3|G6PI_PONPY Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 243 bits (621), Expect = 3e-64 Identities = 111/172 (64%), Positives = 132/172 (76%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL++G +NFE LL+G H MD HF+ TPL Sbjct: 269 WVGGRYSLWSAIGLSIALHVG----------------FDNFEQLLSGAHWMDQHFRTTPL 312 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PV++A+LGI Y++C+ ETH +LPYDQY+HRF+AYFQQGDMESNGK + G V Sbjct: 313 EKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVD 372 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEV 63 + TGPI+WGEPGTNGQHAFYQLIHQGT++IPCDFLIP QT +PI GLHH+V Sbjct: 373 HQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKV 424
Score = 58.5 bits (140), Expect = 2e-08 Identities = 26/32 (81%), Positives = 29/32 (90%) Frame = -3 Query: 730 NAVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +AV+KHFVALSTN KVKEFGID +NMFEFWD Sbjct: 237 SAVAKHFVALSTNTTKVKEFGIDPQNMFEFWD 268
>sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen 36) (SA-36) Length = 558 Score = 243 bits (620), Expect = 4e-64 Identities = 110/172 (63%), Positives = 132/172 (76%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL++G +NFE LL+G H MD HF+ TPL Sbjct: 269 WVGGRYSLWSAIGLSIALHVG----------------FDNFEQLLSGAHWMDQHFRTTPL 312 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PV++A+LGI Y++C+ ETH +LPYDQY+HRF+AYFQQGDMESNGK + G V Sbjct: 313 EKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVD 372 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEV 63 + TGPI+WGEPGTNGQHAFYQLIHQGT++IPCDFLIP QT +PI GLHH++ Sbjct: 373 HQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKI 424
Score = 58.5 bits (140), Expect = 2e-08 Identities = 26/32 (81%), Positives = 29/32 (90%) Frame = -3 Query: 730 NAVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +AV+KHFVALSTN KVKEFGID +NMFEFWD Sbjct: 237 SAVAKHFVALSTNTTKVKEFGIDPQNMFEFWD 268
>sp|Q9N1E2|G6PI_RABIT Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 241 bits (614), Expect = 2e-63 Identities = 109/172 (63%), Positives = 131/172 (76%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL++G +NFE LL+G H MD HF+ TPL Sbjct: 269 WVGGRYSLWSAIGLSIALHVG----------------FDNFEQLLSGAHWMDQHFRTTPL 312 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PV++A+LGI Y++C+ ET +LPYDQY+HRF+AYFQQGDMESNGK + G V Sbjct: 313 EKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQGDMESNGKYITKSGARVD 372 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEV 63 + TGPI+WGEPGTNGQHAFYQLIHQGT++IPCDFLIP QT +PI GLHH++ Sbjct: 373 HQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKI 424
Score = 57.0 bits (136), Expect = 6e-08 Identities = 25/32 (78%), Positives = 28/32 (87%) Frame = -3 Query: 730 NAVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 + V+KHFVALSTN KVKEFGID +NMFEFWD Sbjct: 237 STVAKHFVALSTNTAKVKEFGIDPQNMFEFWD 268
>sp|P08059|G6PI_PIG Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 558 Score = 239 bits (609), Expect = 8e-63 Identities = 109/172 (63%), Positives = 131/172 (76%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL++G +NFE LL+G H MD HF+ TPL Sbjct: 269 WVGGRYSLWSAIGLSIALHVG----------------FDNFEQLLSGAHWMDQHFRTTPL 312 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N PV++A+LGI Y++ + ETH +LPYDQY+HRF+AYFQQGDMESNGK + G V Sbjct: 313 EKNAPVLLALLGIWYINFFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVD 372 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHHEV 63 + TGPI+WGEPGTNGQHAFYQLIHQGT++IPCDFLIP QT +PI GLHH++ Sbjct: 373 HQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKI 424
Score = 58.5 bits (140), Expect = 2e-08 Identities = 26/32 (81%), Positives = 29/32 (90%) Frame = -3 Query: 730 NAVSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 +AV+KHFVALSTN KVKEFGID +NMFEFWD Sbjct: 237 SAVAKHFVALSTNTTKVKEFGIDPQNMFEFWD 268
>sp|Q664W9|G6PI_YERPS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) sp|Q8ZAS2|G6PI_YERPE Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 548 Score = 226 bits (577), Expect = 4e-59 Identities = 110/170 (64%), Positives = 128/170 (75%) Frame = -2 Query: 578 WVGGRYSLWSAIGLSIALYIG*EVYMTQLSLLSLIAGMNNFEALLAGGHAMDCHFKETPL 399 WVGGRYSLWSAIGLSIAL +G E +FE LL+G HAMD HF ETP Sbjct: 266 WVGGRYSLWSAIGLSIALSVGFE----------------HFEQLLSGAHAMDKHFAETPA 309 Query: 398 ENNIPVIMAVLGIMYMHCYKAETHCILPYDQYMHRFSAYFQQGDMESNGKCVNHVGKHVP 219 E N+PV++A++GI Y + + AET ILPYDQYMHRF AYFQQG+MESNGK V+ G V Sbjct: 310 EKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGHPVD 369 Query: 218 YSTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFLIPAQTHNPINNGLHH 69 Y TGPIIWGEPGTNGQHAFYQLIHQGT+LIPCDF+ PA +HNP+++ HH Sbjct: 370 YQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSD--HH 417
Score = 49.7 bits (117), Expect = 9e-06 Identities = 22/30 (73%), Positives = 23/30 (76%) Frame = -3 Query: 724 VSKHFVALSTNIPKVKEFGIDEKNMFEFWD 635 V+KHF ALSTN V EFGID NMFEFWD Sbjct: 236 VAKHFAALSTNAKAVGEFGIDTNNMFEFWD 265
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 99,142,943 Number of Sequences: 369166 Number of extensions: 2164270 Number of successful extensions: 5007 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4537 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4822 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7454154400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)