Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_02031
(870 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q09461|YQ51_CAEEL Putative mitochondrial carrier C16C10.1 190 5e-48
sp|Q9BZJ4|CG69_HUMAN Mitochondrial carrier protein CGI-69 167 3e-41
sp|Q9D8K8|CG69_MOUSE Mitochondrial carrier protein CGI-69 h... 160 3e-39
sp|P53320|YG5F_YEAST Putative mitochondrial carrier YGR257C 144 4e-34
sp|Q5IS35|DNC_MACFA Mitochondrial deoxynucleotide carrier (... 67 5e-11
sp|P39953|YEA6_YEAST Putative mitochondrial carrier YEL006W 65 3e-10
sp|Q9DAM5|DNC_MOUSE Mitochondrial deoxynucleotide carrier (... 64 4e-10
sp|Q9HC21|DNC_HUMAN Mitochondrial deoxynucleotide carrier (... 63 1e-09
sp|Q9QXX4|CMC2_MOUSE Calcium-binding mitochondrial carrier ... 62 2e-09
sp|Q9UJS0|CMC2_HUMAN Calcium-binding mitochondrial carrier ... 62 2e-09
>sp|Q09461|YQ51_CAEEL Putative mitochondrial carrier C16C10.1
Length = 360
Score = 190 bits (482), Expect = 5e-48
Identities = 109/278 (39%), Positives = 161/278 (57%), Gaps = 6/278 (2%)
Frame = +2
Query: 50 IWQRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNN 229
+ Q++ +SS+GA+VTS+ +TPLDV+KIR+Q Q++P GECF Y NGLM+H+C +
Sbjct: 36 VLQQVSASSSGAIVTSLFMTPLDVVKIRLQQQTRPFPKGECFYYHNGLMEHVCV----SC 91
Query: 230 KLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLK 409
++ Y+R F + DA KI + EG+ SLWSGLSPT+++A+P V Y+T
Sbjct: 92 EVRKPCEWYQRPGNFRGTADAIVKIARHEGIRSLWSGLSPTMVMALPATVFYFTT----- 146
Query: 410 YVTGYANYTKSPKNNLISSRGFLNKEDLLPP------LCGTVARLVAQTTIAPLELLRTK 571
Y N + K + R F + E PP + G VAR +A T ++P+E++RTK
Sbjct: 147 ----YDNLSVWLKKKMCCRRAF-SPEKWTPPDWSAAAVAGIVARTIAVTVVSPIEMIRTK 201
Query: 572 MQSKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQYLINN 751
MQSK+L Y E+ ++ S++ GI+ + G PTM RDIP+S W Y+ K N
Sbjct: 202 MQSKRLTYHEIGHLVRSSMATKGISSFYLGWTPTMLRDIPFSGIYWAGYDLFK----TNL 257
Query: 752 KRFIEDSYVPHHLIFLYSACGAVAAGIVSHPFDVTKTH 865
+R + P + F+ A V A I +HPFDV KT+
Sbjct: 258 QRRQGPDHNPFVVSFVSGAAAGVVASIFTHPFDVIKTN 295
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/167 (24%), Positives = 73/167 (43%), Gaps = 5/167 (2%)
Frame = +2
Query: 245 TRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGY 424
T++ + L ++ R + T+G+ S + G +PT++ IP IY+ GY
Sbjct: 200 TKMQSKRLTYHEIGHLVRSSMATKGISSFYLGWTPTMLRDIPFSGIYWA---------GY 250
Query: 425 ANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKMQSK-KLKYFE 601
+ K NL +G + ++ + G A +VA P ++++T Q + +
Sbjct: 251 DLF----KTNLQRRQGPDHNPFVVSFVSGAAAGVVASIFTHPFDVIKTNCQIRIGGSIDD 306
Query: 602 MRKIITSAI----NQGGITILWRGLGPTMWRDIPYSITLWFIYEYLK 730
M K IT+ I + GI+ GL P + + P + YEY K
Sbjct: 307 MNKSITTVIKDMYHSRGISAFSSGLVPRLVKVSPSCAIMISFYEYFK 353
>sp|Q9BZJ4|CG69_HUMAN Mitochondrial carrier protein CGI-69
Length = 359
Score = 167 bits (423), Expect = 3e-41
Identities = 102/295 (34%), Positives = 154/295 (52%), Gaps = 24/295 (8%)
Frame = +2
Query: 56 QRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVS-----------------------G 166
Q++V+S TGAVVTS+ +TPLDV+K+R+Q+Q + S G
Sbjct: 13 QQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTG 72
Query: 167 ECFIYCNGLMDHICQFVNGNNKLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLS 346
+C +YCNG+++ + NG ++ +F + DAF KIV+ EG +LWSGL
Sbjct: 73 KCLLYCNGVLEPLYLCPNGAR----CATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLP 128
Query: 347 PTLILAIPQVVIYYTLNDWLK-YVTGYANYTKSPKNNLISSRGFLNKEDLLPPLCGTVAR 523
TL++ +P IY+T D LK ++ G A L + P + G +AR
Sbjct: 129 ATLVMTVPATAIYFTAYDQLKAFLCGRA----------------LTSDLYAPMVAGALAR 172
Query: 524 LVAQTTIAPLELLRTKMQSKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSIT 703
L T I+PLEL+RTK+Q++ + Y E+ + +A+ QGG LW G GPT RD+P+S
Sbjct: 173 LGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSAL 232
Query: 704 LWFIYEYLKKQYLINNKRFIEDSYVPHHLIFLYSACGAVAAGIVSHPFDVTKTHR 868
WF YE +K +N R + + V + F+ A +++ PFDV KT R
Sbjct: 233 YWFNYELVKS--WLNGLRPKDQTSV--GMSFVAGGISGTVAAVLTLPFDVVKTQR 283
>sp|Q9D8K8|CG69_MOUSE Mitochondrial carrier protein CGI-69 homolog
Length = 359
Score = 160 bits (406), Expect = 3e-39
Identities = 97/295 (32%), Positives = 152/295 (51%), Gaps = 24/295 (8%)
Frame = +2
Query: 56 QRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVS-----------------------G 166
Q++V+S GAVVTS+ +TPLDV+K+R+Q+Q S G
Sbjct: 13 QQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPSATSELTTPSRFWSLSYTKSSSALQSPG 72
Query: 167 ECFIYCNGLMDHICQFVNGNNKLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLS 346
+C +YCNG+++ + NG ++ +F + DAF KIV+ EG +LWSGL
Sbjct: 73 KCLLYCNGVLEPLYLCPNGTR----CATWFQDPTRFTGTLDAFVKIVRHEGTRTLWSGLP 128
Query: 347 PTLILAIPQVVIYYTLNDWLK-YVTGYANYTKSPKNNLISSRGFLNKEDLLPPLCGTVAR 523
TL++ +P IY+T D LK ++ G + L + P + G +AR
Sbjct: 129 ATLVMTVPATAIYFTAYDQLKAFLCGQS----------------LTSDLYAPMVAGALAR 172
Query: 524 LVAQTTIAPLELLRTKMQSKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSIT 703
+ T ++PLEL+RTK+Q++ + Y E+ + +A+ QGG LW G GPT RD+P+S
Sbjct: 173 MGTVTVVSPLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLGWGPTALRDVPFSAL 232
Query: 704 LWFIYEYLKKQYLINNKRFIEDSYVPHHLIFLYSACGAVAAGIVSHPFDVTKTHR 868
WF YE +K ++ R + + V + F+ + A ++ PFDV KT R
Sbjct: 233 YWFNYELVKS--WLSGLRPKDQTSV--GISFVAGGISGMVAATLTLPFDVVKTQR 283
>sp|P53320|YG5F_YEAST Putative mitochondrial carrier YGR257C
Length = 366
Score = 144 bits (362), Expect = 4e-34
Identities = 96/311 (30%), Positives = 162/311 (52%), Gaps = 33/311 (10%)
Frame = +2
Query: 29 NENENFKIWQRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMD--- 199
N + + + +R++S+ G+V+TS+++TP+DV++IR+Q Q + +C C+G +
Sbjct: 5 NTSNSLTLKERMLSAGAGSVLTSLILTPMDVVRIRLQQQQ---MIPDCS--CDGAAEVPN 59
Query: 200 ------HICQFVNGNNKLLTSTRLY------------KRDLKFNNSFDAFRKIVKTEGVV 325
+ F N + L + +++ LKFN + +AF KI EG+
Sbjct: 60 AVSSGSKMKTFTNVGGQNLNNAKIFWESACFQELHCKNSSLKFNGTLEAFTKIASVEGIT 119
Query: 326 SLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGYANYTKSPKNNLISSRGFLNKEDLLPPL 505
SLW G+S TL++AIP ++Y++ ++++ V+ A+ L P
Sbjct: 120 SLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIAS----------------TYPTLNPLF 163
Query: 506 CGTVARLVAQTTIAPLELLRTKMQ-----SKKLKYFEMRKIITSAINQ-----GGITILW 655
CG +AR+ A T+IAPLEL++TK+Q SK K + M K + + Q G L+
Sbjct: 164 CGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALF 223
Query: 656 RGLGPTMWRDIPYSITLWFIYEYLKKQYLINNKRFI-EDSYVPHHLIFLYSAC-GAVAAG 829
+GL T+WRD+P+S W YE K++ +++ RF +D+ H + S C + A
Sbjct: 224 KGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASGCISGMIAA 283
Query: 830 IVSHPFDVTKT 862
I +HPFDV KT
Sbjct: 284 ICTHPFDVGKT 294
>sp|Q5IS35|DNC_MACFA Mitochondrial deoxynucleotide carrier (Solute carrier family 25,
member 19)
Length = 320
Score = 67.4 bits (163), Expect = 5e-11
Identities = 58/232 (25%), Positives = 98/232 (42%), Gaps = 4/232 (1%)
Frame = +2
Query: 56 QRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKL 235
Q V+ S +VT L++P DVIKIR Q Q +
Sbjct: 17 QVAVAGSVSGLVTRALISPFDVIKIRFQLQHE---------------------------- 48
Query: 236 LTSTRLYKRD--LKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLK 409
RL +RD K++ F A R+I++ EG+ + W G P IL+I + + + L
Sbjct: 49 ----RLSRRDPNAKYHGIFQASRQILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLT 104
Query: 410 YVTGYANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKM--QSK 583
+ + ++ +R F + +CG +A A T+ P+++LRT+ Q +
Sbjct: 105 ELV--------HRGSVYDAREF-----SVHFVCGGLAACTATLTVHPVDVLRTRFAAQGE 151
Query: 584 KLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQY 739
Y +R + + G + ++GL PT+ PY+ + Y LK Y
Sbjct: 152 PKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLY 203
Score = 47.4 bits (111), Expect = 5e-05
Identities = 46/231 (19%), Positives = 89/231 (38%), Gaps = 11/231 (4%)
Frame = +2
Query: 65 VSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTS 244
V A ++ V P+DV++ R AQ +P V
Sbjct: 123 VCGGLAACTATLTVHPVDVLRTRFAAQGEPKV---------------------------- 154
Query: 245 TRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGY 424
+N A + ++EG + GL+PTLI P + ++ LK++ +
Sbjct: 155 ---------YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKW 205
Query: 425 ANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKMQ--------- 577
A + KN E+L LCG+ A ++++T PL+L + ++Q
Sbjct: 206 AMPAEGKKN-----------ENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA 254
Query: 578 --SKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEY 724
+ +Y + + + G ++GL P++ + + ++F YE+
Sbjct: 255 AFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFWYEF 305
>sp|P39953|YEA6_YEAST Putative mitochondrial carrier YEL006W
Length = 335
Score = 64.7 bits (156), Expect = 3e-10
Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
Frame = +2
Query: 230 KLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLK 409
+L+ T + K + + D FRKI++ EG +L++GL P L L + V I + L + LK
Sbjct: 165 RLMLQTGIGKYSTHYKGTIDTFRKIIQQEGAKALYAGLVPAL-LGMLNVAIQFPLYENLK 223
Query: 410 YVTGYANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKMQSK-- 583
GY+ T ++ SS N + L+ L ++++VA T P E+LRT+MQ K
Sbjct: 224 IRFGYSEST-DVSTDVTSS----NFQKLI--LASMLSKMVASTVTYPHEILRTRMQLKSD 276
Query: 584 --KLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKK 733
+ +I Q G + G + R +P ++ +EY KK
Sbjct: 277 LPNTVQRHLLPLIKITYRQEGFAGFYSGFATNLVRTVPAAVVTLVSFEYSKK 328
Score = 48.1 bits (113), Expect = 3e-05
Identities = 61/269 (22%), Positives = 103/269 (38%), Gaps = 3/269 (1%)
Frame = +2
Query: 65 VSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTS 244
+S + ++++LV P DV K R+QAQ G +
Sbjct: 43 ISGALSGALSAMLVCPFDVAKTRLQAQ-------------------------GLQNMTHQ 77
Query: 245 TRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWL-KYVTG 421
++ YK F F I K EG L+ GL PT++ IP ++IY+++ D+ KY
Sbjct: 78 SQHYK------GFFGTFATIFKDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKYSVD 131
Query: 422 YANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKMQSKKLKYFE 601
++ N + P+ RL+ QT I K
Sbjct: 132 IFPHSPFLSNASSAITAGAISTVATNPIWVVKTRLMLQTGIGKYS------THYKGTIDT 185
Query: 602 MRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQYLINNKRFIEDSYVP 781
RKI I Q G L+ GL P + + +I + +YE LK ++ + +
Sbjct: 186 FRKI----IQQEGAKALYAGLVPALLGMLNVAIQ-FPLYENLKIRFGYSESTDVSTDVTS 240
Query: 782 HHL--IFLYSACGAVAAGIVSHPFDVTKT 862
+ + L S + A V++P ++ +T
Sbjct: 241 SNFQKLILASMLSKMVASTVTYPHEILRT 269
>sp|Q9DAM5|DNC_MOUSE Mitochondrial deoxynucleotide carrier (Solute carrier family 25
member 19)
Length = 318
Score = 64.3 bits (155), Expect = 4e-10
Identities = 65/268 (24%), Positives = 113/268 (42%), Gaps = 3/268 (1%)
Frame = +2
Query: 65 VSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTS 244
V+ S VT L++PLDVIKIR Q Q + L +
Sbjct: 20 VAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSD------------------------- 54
Query: 245 TRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGY 424
+ K++ F A ++I++ EG + W G P IL+I + + + L +
Sbjct: 55 -----PNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYGAVQFLAFEELTELLYQ 109
Query: 425 ANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKM--QSKKLKYF 598
AN ++ + S F+ CG ++ A T+ P+++LRT++ Q + Y
Sbjct: 110 ANLYQTHQ----FSAHFV---------CGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYN 156
Query: 599 EMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQYLINNKRFIEDSYV 778
+R+ I + G + ++GL PT+ PY+ + Y LK+ Y + D
Sbjct: 157 NLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAY---DWLIPPDGKQ 213
Query: 779 PHHLIFLYSACGA-VAAGIVSHPFDVTK 859
+L L CG+ V + ++P D+ K
Sbjct: 214 TGNLKNLLCGCGSGVISKTFTYPLDLIK 241
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/230 (20%), Positives = 88/230 (38%), Gaps = 11/230 (4%)
Frame = +2
Query: 65 VSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTS 244
V A ++ V P+DV++ R+ AQ +P +
Sbjct: 123 VCGGLSAGTATLTVHPVDVLRTRLAAQGEPKI---------------------------- 154
Query: 245 TRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGY 424
+NN +A R + KTEG + GL+PT+I P + ++ LK +
Sbjct: 155 ---------YNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDW 205
Query: 425 ANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKMQ--------- 577
LI G +L LCG + ++++T PL+L++ ++Q
Sbjct: 206 ----------LIPPDG-KQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARS 254
Query: 578 --SKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYE 721
+ Y + + + + G ++GL P++ + + ++F YE
Sbjct: 255 AFGQVRSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMKAALSTGFMFFWYE 304
>sp|Q9HC21|DNC_HUMAN Mitochondrial deoxynucleotide carrier (Solute carrier family 25,
member 19) (Mitochondrial uncoupling protein 1)
Length = 320
Score = 62.8 bits (151), Expect = 1e-09
Identities = 55/238 (23%), Positives = 97/238 (40%), Gaps = 2/238 (0%)
Frame = +2
Query: 32 ENENFKIWQRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQ 211
+ N +Q V+ S +VT L++P DVIKIR Q Q + L +
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSD-------------- 54
Query: 212 FVNGNNKLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYT 391
K++ A R+I++ EG + W G P IL+I + +
Sbjct: 55 ----------------PSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFL 98
Query: 392 LNDWLKYVTGYANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTK 571
+ L + + ++ +R F + +CG +A +A T+ P+++LRT+
Sbjct: 99 SFEMLTELVH--------RGSVYDAREFS-----VHFVCGGLAACMATLTVHPVDVLRTR 145
Query: 572 M--QSKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQY 739
Q + Y +R + + G + ++GL PT+ PY+ + Y LK Y
Sbjct: 146 FAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLY 203
Score = 47.8 bits (112), Expect = 4e-05
Identities = 46/231 (19%), Positives = 90/231 (38%), Gaps = 11/231 (4%)
Frame = +2
Query: 65 VSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTS 244
V A + ++ V P+DV++ R AQ +P V
Sbjct: 123 VCGGLAACMATLTVHPVDVLRTRFAAQGEPKV---------------------------- 154
Query: 245 TRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGY 424
+N A + ++EG + GL+PTLI P + ++ LK++ +
Sbjct: 155 ---------YNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKW 205
Query: 425 ANYTKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTTIAPLELLRTKMQ--------- 577
A + KN E+L LCG+ A ++++T PL+L + ++Q
Sbjct: 206 AIPAEGKKN-----------ENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA 254
Query: 578 --SKKLKYFEMRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEY 724
+ +Y + + + G ++GL P++ + + ++F YE+
Sbjct: 255 AFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
>sp|Q9QXX4|CMC2_MOUSE Calcium-binding mitochondrial carrier protein Aralar2
(Mitochondrial aspartate glutamate carrier 2) (Solute
carrier family 25 member 13) (Citrin)
Length = 676
Score = 62.4 bits (150), Expect = 2e-09
Identities = 66/268 (24%), Positives = 107/268 (39%), Gaps = 5/268 (1%)
Frame = +2
Query: 74 STGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTSTRL 253
S V + V P+D++K RMQ Q ST
Sbjct: 337 SIAGAVGATAVYPIDLVKTRMQNQR-------------------------------STGS 365
Query: 254 YKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGYANY 433
+ +L + NSFD F+K+++ EG L+ GL P L+ P+ I T+ND+++
Sbjct: 366 FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVR-------- 417
Query: 434 TKSPKNNLISSRGFLNKEDLLPPLCGTVARLVAQTT----IAPLELLRTKMQSKKLKYFE 601
F++K+ +P L A A + PLE+++ ++Q
Sbjct: 418 -----------DKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG 466
Query: 602 MRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQYLINNKRFIEDSYV- 778
R S + G +++G RDIP+S + Y ++K + ED V
Sbjct: 467 PRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFA------NEDGQVS 520
Query: 779 PHHLIFLYSACGAVAAGIVSHPFDVTKT 862
P L+ + G AA +V+ P DV KT
Sbjct: 521 PGSLLLAGAIAGMPAASLVT-PADVIKT 547
Score = 36.2 bits (82), Expect = 0.12
Identities = 30/129 (23%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Frame = +2
Query: 29 NENENFKIWQRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHIC 208
NE+ L++ + + + LVTP DVIK R+Q ++ +G+
Sbjct: 514 NEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAAR---AGQT------------ 558
Query: 209 QFVNGNNKLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQ----V 376
+N D FRKI++ EG +LW G++ + + PQ +
Sbjct: 559 --------------------TYNGVTDCFRKILREEGPKALWKGVAARVFRSSPQFGVTL 598
Query: 377 VIYYTLNDW 403
+ Y L W
Sbjct: 599 LTYELLQRW 607
>sp|Q9UJS0|CMC2_HUMAN Calcium-binding mitochondrial carrier protein Aralar2
(Mitochondrial aspartate glutamate carrier 2) (Solute
carrier family 25 member 13) (Citrin)
Length = 675
Score = 62.4 bits (150), Expect = 2e-09
Identities = 66/268 (24%), Positives = 106/268 (39%), Gaps = 5/268 (1%)
Frame = +2
Query: 74 STGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHICQFVNGNNKLLTSTRL 253
S V + V P+D++K RMQ Q ST
Sbjct: 336 SVAGAVGATAVYPIDLVKTRMQNQR-------------------------------STGS 364
Query: 254 YKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQVVIYYTLNDWLKYVTGYANY 433
+ +L + NSFD F+K+++ EG L+ GL P L+ P+ I T+ND+++
Sbjct: 365 FVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVR-------- 416
Query: 434 TKSPKNNLISSRGFLNKEDLLP----PLCGTVARLVAQTTIAPLELLRTKMQSKKLKYFE 601
F++K+ +P L G A PLE+++ ++Q
Sbjct: 417 -----------DKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTG 465
Query: 602 MRKIITSAINQGGITILWRGLGPTMWRDIPYSITLWFIYEYLKKQYLINNKRFIEDSYV- 778
R S + G +++G RDIP+S + Y ++K + ED V
Sbjct: 466 PRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFA------NEDGQVS 519
Query: 779 PHHLIFLYSACGAVAAGIVSHPFDVTKT 862
P L+ + G AA +V+ P DV KT
Sbjct: 520 PGSLLLAGAIAGMPAASLVT-PADVIKT 546
Score = 33.9 bits (76), Expect = 0.60
Identities = 29/129 (22%), Positives = 49/129 (37%), Gaps = 4/129 (3%)
Frame = +2
Query: 29 NENENFKIWQRLVSSSTGAVVTSILVTPLDVIKIRMQAQSKPLVSGECFIYCNGLMDHIC 208
NE+ L++ + + + LVTP DVIK R+Q ++ +G+
Sbjct: 513 NEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAAR---AGQT------------ 557
Query: 209 QFVNGNNKLLTSTRLYKRDLKFNNSFDAFRKIVKTEGVVSLWSGLSPTLILAIPQ----V 376
++ D FRKI++ EG +LW G + + PQ +
Sbjct: 558 --------------------TYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTL 597
Query: 377 VIYYTLNDW 403
+ Y L W
Sbjct: 598 LTYELLQRW 606
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,277,303
Number of Sequences: 369166
Number of extensions: 1747395
Number of successful extensions: 5268
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4688
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5163
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8598109270
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)