Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01977
(422 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P44849|Y736_HAEIN Hypothetical sodium-dependent transpor... 65 6e-11
sp|Q58715|YD19_METJA Hypothetical sodium-dependent transpor... 58 7e-09
sp|Q9NP91|S6A20_HUMAN Sodium- and chloride-dependent transp... 54 1e-07
sp|Q64093|S6A20_RAT Sodium- and chloride-dependent transpor... 53 2e-07
sp|Q9GZN6|S6A16_HUMAN Orphan sodium- and chloride-dependent... 53 3e-07
sp|O88576|S6A18_MOUSE Sodium- and chloride-dependent transp... 53 3e-07
sp|P45320|YG90_HAEIN Hypothetical sodium-dependent transpor... 52 5e-07
sp|O88575|S6A20_MOUSE Sodium- and chloride-dependent transp... 51 9e-07
sp|Q62687|S6A18_RAT Sodium- and chloride-dependent transpor... 50 2e-06
sp|Q96N87|S6A18_HUMAN Sodium- and chloride-dependent transp... 50 2e-06
>sp|P44849|Y736_HAEIN Hypothetical sodium-dependent transporter HI0736
Length = 508
Score = 65.1 bits (157), Expect = 6e-11
Identities = 35/110 (31%), Positives = 57/110 (51%)
Frame = +1
Query: 82 MGGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYGFNFLFTGDWNTLTNPSLYLDGI 261
MG K I +++ VL+P L+ + + + YS L + G + LFT DW+ L+NPS+++
Sbjct: 174 MGVQKGIAKVSSVLMPVLVVMFMVLVIYSLFLPGAAKGLDALFTPDWSKLSNPSVWIAAY 233
Query: 262 SQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESFLASMTIF 411
Q F G + YA YL K + + L + AN+ LA + +F
Sbjct: 234 GQIFFSLSIGFGIMVTYASYLKKESDLTGSGLVVGFANSSFEVLAGIGVF 283
>sp|Q58715|YD19_METJA Hypothetical sodium-dependent transporter MJ1319
Length = 492
Score = 58.2 bits (139), Expect = 7e-09
Identities = 34/120 (28%), Positives = 63/120 (52%)
Frame = +1
Query: 61 IIISASVMGGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYGFNFLFTGDWNTLTNP 240
+I+SA + G+ E+ N +++P LL +++ + + TL + G + T D++ L N
Sbjct: 164 LILSAGIKNGL---EKANKIMIPFLLFLIILLVLNALTLPGALTGIEWYLTPDFSALFNY 220
Query: 241 SLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESFLASMTIFLTV 420
+++L SQ F G + AYA YL K + + ++ + + N SFLA +F T+
Sbjct: 221 NVWLSAFSQIFFSLSLGFGILIAYASYLPKKSDLTINAVTVSLLNCGFSFLAGFAVFGTL 280
>sp|Q9NP91|S6A20_HUMAN Sodium- and chloride-dependent transporter XTRP3 (Solute carrier
family 6 member 20) (Neurotransmitter transporter rB21A
homolog)
Length = 592
Score = 54.3 bits (129), Expect = 1e-07
Identities = 27/120 (22%), Positives = 55/120 (45%)
Frame = +1
Query: 52 LCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYGFNFLFTGDWNTL 231
L ++++ ++ G + ++ +L+ TLH + G ++FT L
Sbjct: 176 LAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQL 235
Query: 232 TNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESFLASMTIF 411
NP +++ +Q F G G + A+A Y SN+ K+++ + + N+ S AS+ F
Sbjct: 236 ANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTF 295
>sp|Q64093|S6A20_RAT Sodium- and chloride-dependent transporter XTRP3 (Solute carrier
family 6 member 20) (Neurotransmitter transporter rB21A)
Length = 616
Score = 53.1 bits (126), Expect = 2e-07
Identities = 28/121 (23%), Positives = 55/121 (45%)
Frame = +1
Query: 49 TLCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYGFNFLFTGDWNT 228
TL ++++ ++ G + ++ +L+ TLH + G ++FT
Sbjct: 199 TLAWLMVYLCILRGTESTGKVVYFTALMPYCVLIIYLVRGLTLHGATNGLMYMFTPKIEQ 258
Query: 229 LTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESFLASMTI 408
L NP +++ +Q F G G + A+A Y SN K+++ + + N+ S AS+
Sbjct: 259 LANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASIVT 318
Query: 409 F 411
F
Sbjct: 319 F 319
>sp|Q9GZN6|S6A16_HUMAN Orphan sodium- and chloride-dependent neurotransmitter transporter
NTT5 (Solute carrier family 6 member 16)
Length = 736
Score = 52.8 bits (125), Expect = 3e-07
Identities = 29/114 (25%), Positives = 58/114 (50%)
Frame = +1
Query: 40 LPYTLCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYGFNFLFTGD 219
LP+ LC+ ++ A ++ G+K ++ VLV I++G F + L +++G L
Sbjct: 270 LPFFLCWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFIRTLLLEGAKFGLQQLVVAK 329
Query: 220 WNTLTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNL 381
+ + N S++ Q +TG LG + + A Y+ +SN+ + + + + N L
Sbjct: 330 ISDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINLL 383
>sp|O88576|S6A18_MOUSE Sodium- and chloride-dependent transporter XTRP2 (Solute carrier
family 6 member 18)
Length = 615
Score = 52.8 bits (125), Expect = 3e-07
Identities = 38/127 (29%), Positives = 60/127 (47%), Gaps = 2/127 (1%)
Frame = +1
Query: 37 FLPYTLCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFY--STTLHYSEYGFNFLF 210
FL C+ + V+ GI+ ++ + AL L+ F TL + G +LF
Sbjct: 183 FLCLVACWSTVYLCVIRGIESTGKV--IYFTALFPYLVLTIFLIRGLTLPGATEGLIYLF 240
Query: 211 TGDWNTLTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESF 390
T + TL NP ++LD +Q F A G A+A Y N+ K ++ I + N++ S
Sbjct: 241 TPNMKTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSL 300
Query: 391 LASMTIF 411
AS+ IF
Sbjct: 301 YASIAIF 307
>sp|P45320|YG90_HAEIN Hypothetical sodium-dependent transporter HI1690
Length = 457
Score = 52.0 bits (123), Expect = 5e-07
Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 2/132 (1%)
Frame = +1
Query: 22 SSNWSFLPYTLCFIIISASVM--GGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYG 195
+S + + YTL F+I++ ++ G I IER L+P L L+G+ + TL + G
Sbjct: 153 NSPYEIIFYTLLFVIVNYIILAKGIIGGIERSVKYLMPLLFIFLIGMVIRNVTLPGAMEG 212
Query: 196 FNFLFTGDWNTLTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIAN 375
F D++ +T P L++ + Q F G + + YL K +++ ++ N
Sbjct: 213 ITFYLKPDFSKIT-PQLFIFVLGQVFFALSLGFGVLITLSSYLNKEENLIHTAVITGFTN 271
Query: 376 NLESFLASMTIF 411
+ + LA IF
Sbjct: 272 TIIAVLAGFMIF 283
>sp|O88575|S6A20_MOUSE Sodium- and chloride-dependent transporter XTRP3 (Solute carrier
family 6 member 20)
Length = 635
Score = 51.2 bits (121), Expect = 9e-07
Identities = 27/121 (22%), Positives = 55/121 (45%)
Frame = +1
Query: 49 TLCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFYSTTLHYSEYGFNFLFTGDWNT 228
TL ++++ ++ G + ++ +L+ TLH + G ++FT
Sbjct: 218 TLAWLMVYLCILRGTESTGKVVYFTTSLPYFVLIIYLVRGLTLHGATNGLAYMFTPKIEQ 277
Query: 229 LTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESFLASMTI 408
L NP +++ +Q F G G + A+A Y SN K++L + + N+ + +S+
Sbjct: 278 LANPKAWINAATQIFFSLGLGCGGLIAFASYNEPSNDCQKHALIVSVINSTTAIFSSIVT 337
Query: 409 F 411
F
Sbjct: 338 F 338
>sp|Q62687|S6A18_RAT Sodium- and chloride-dependent transporter XTRP2 (Solute carrier
family 6 member 18) (Renal osmotic stress-induced Na-Cl
organic solute cotransporter) (ROSIT)
Length = 615
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 2/127 (1%)
Frame = +1
Query: 37 FLPYTLCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFY--STTLHYSEYGFNFLF 210
FL C+ + V+ GI+ ++ + AL L+ F TL + G +LF
Sbjct: 183 FLCLVACWTTVYLCVIRGIESTGKV--IYFTALFPYLVLTIFLIRGLTLPGATEGLTYLF 240
Query: 211 TGDWNTLTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLESF 390
T + L N ++LD +Q F A G A+A Y N+ K ++ I + N++ S
Sbjct: 241 TPNMKILQNSRVWLDAATQIFFSLSLAFGGHIAFASYNQPRNNCEKDAVTIALVNSMTSL 300
Query: 391 LASMTIF 411
AS+TIF
Sbjct: 301 YASITIF 307
>sp|Q96N87|S6A18_HUMAN Sodium- and chloride-dependent transporter XTRP2 (Solute carrier
family 6 member 18)
Length = 628
Score = 50.1 bits (118), Expect = 2e-06
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
Frame = +1
Query: 31 WSFLPYTLCFIIISASVMGGIKVIERINMVLVPALLAILLGIFFY--STTLHYSEYGFNF 204
W + + ++ V+ GI+ ++ + AL L+ F TL + G +
Sbjct: 182 WLLICLAASWAVVYMCVIRGIETTGKV--IYFTALFPYLVLTIFLIRGLTLPGATKGLIY 239
Query: 205 LFTGDWNTLTNPSLYLDGISQNAFDTGAALGQITAYAMYLTKSNSIMKYSLFIPIANNLE 384
LFT + + L NP ++LD +Q F A G A+A Y + N K ++ I + N +
Sbjct: 240 LFTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMT 299
Query: 385 SFLASMTIF 411
S AS+ +F
Sbjct: 300 SLYASIAVF 308
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,012,087
Number of Sequences: 369166
Number of extensions: 948403
Number of successful extensions: 2682
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2632
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2682
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2052714815
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)