Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01961
(865 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P25822|PUM_DROME Maternal pumilio protein 182 8e-46
sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 (Pumilio-2) 172 8e-43
sp|Q80U58|PUM2_MOUSE Pumilio homolog 2 171 2e-42
sp|Q14671|PUM1_HUMAN Pumilio homolog 1 (Pumilio-1) (HsPUM) 169 9e-42
sp|Q80U78|PUM1_MOUSE Pumilio homolog 1 167 5e-41
sp|Q07807|PUF3_YEAST PUF3 protein 127 5e-29
sp|P39016|MPT5_YEAST Suppressor protein MPT5 (HTR1 protein) 81 4e-15
sp|Q92359|YDHE_SCHPO Hypothetical protein C6G9.14 in chromo... 72 2e-12
sp|P25339|PUF4_YEAST PUF4 protein 66 1e-10
sp|Q10238|YD15_SCHPO Putative regulatory protein C4G9.05 62 2e-09
>sp|P25822|PUM_DROME Maternal pumilio protein
Length = 1533
Score = 182 bits (463), Expect = 8e-46
Identities = 94/148 (63%), Positives = 113/148 (76%)
Frame = +3
Query: 420 GVVGNLKDGVTRSRLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNE 599
GV G + G RSRLLEDFR R L L+D++ H+VEF+QDQHGSRFIQQKL+ ++ E
Sbjct: 1083 GVGGAPQPG--RSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAE 1140
Query: 600 KSMVFREILPQCYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRV 779
K MVF EIL YSLMTDVFGNYVIQ+FF+ GTPEQ LG +++ VLQL+LQMYGCRV
Sbjct: 1141 KQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRV 1200
Query: 780 IQKALETVSKVTQINIVRELEGSVIKCV 863
IQKALE++S Q IV EL+G V+KCV
Sbjct: 1201 IQKALESISPEQQQEIVHELDGHVLKCV 1228
Score = 64.3 bits (155), Expect = 4e-10
Identities = 37/115 (32%), Positives = 60/115 (52%)
Frame = +3
Query: 495 TLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVI 674
TL +Q + GHV++ A +G R IQ+ L+ S ++ + E+ + D GN+V+
Sbjct: 1179 TLGMQ-VKGHVLQLALQMYGCRVIQKALESISPEQQQEIVHELDGHVLKCVKDQNGNHVV 1237
Query: 675 QRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
Q+ + P +Q + + + QV LS YGCRVIQ+ LE + I+ EL
Sbjct: 1238 QKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDEL 1292
Score = 53.5 bits (127), Expect = 7e-07
Identities = 32/117 (27%), Positives = 55/117 (47%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRF 683
+ ++ GHV++ +DQ+G+ +Q+ ++ + Q YSL T +G VIQR
Sbjct: 1217 VHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRI 1276
Query: 684 FDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELEGSVI 854
+ T EQ + D + QL YG VIQ LE + + ++ + G V+
Sbjct: 1277 LEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQEDKSILINSVRGKVL 1333
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/107 (26%), Positives = 53/107 (49%)
Frame = +3
Query: 519 GHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGT 698
G V + +G R IQ+ L+ + + + + E+ L+ D +GNYVIQ + G
Sbjct: 1258 GQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGK 1317
Query: 699 PEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
E IL + +R +VL LS + V++K + ++ + ++ E+
Sbjct: 1318 QEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEV 1364
Score = 45.4 bits (106), Expect = 2e-04
Identities = 36/159 (22%), Positives = 63/159 (39%), Gaps = 40/159 (25%)
Frame = +3
Query: 459 RLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREI----- 623
R+LE A + TT L ++ H + QDQ+G+ IQ L+ +KS++ +
Sbjct: 1275 RILEHCTAEQ-TTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQEDKSILINSVRGKVL 1333
Query: 624 -----------LPQCYS------------------------LMTDVFGNYVIQRFFDLGT 698
+ +C + +M D + NYV+Q+ D+
Sbjct: 1334 VLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDNALHVMMKDQYANYVVQKMIDVSE 1393
Query: 699 PEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVT 815
P Q++ L +IR + L YG + K + K+T
Sbjct: 1394 PTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKIT 1432
>sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 (Pumilio-2)
Length = 1066
Score = 172 bits (437), Expect = 8e-43
Identities = 87/139 (62%), Positives = 107/139 (76%), Gaps = 2/139 (1%)
Frame = +3
Query: 453 RSRLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ 632
RSRLLEDFR NR L L+D+ GH+VEF+QDQHGSRFIQQKL+ ++ E+ MVF EIL
Sbjct: 707 RSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEILQA 766
Query: 633 CYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKV 812
Y LMTDVFGNYVIQ+FF+ G+ +Q L RIR VL L+LQMYGCRVIQKALE++S
Sbjct: 767 AYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSD 826
Query: 813 TQI--NIVRELEGSVIKCV 863
Q+ +V+EL+G V+KCV
Sbjct: 827 QQVISEMVKELDGHVLKCV 845
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/111 (33%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Frame = +3
Query: 513 ISGHVVEFAQDQHGSRFIQQKLQESSHNEK--SMVFREILPQCYSLMTDVFGNYVIQRFF 686
I GHV+ A +G R IQ+ L+ S +++ S + +E+ + D GN+V+Q+
Sbjct: 799 IRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCI 858
Query: 687 DLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
+ P+ +Q + D + QV LS YGCRVIQ+ LE + + I+ EL
Sbjct: 859 ECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEEL 909
Score = 52.8 bits (125), Expect = 1e-06
Identities = 29/107 (27%), Positives = 51/107 (47%)
Frame = +3
Query: 519 GHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGT 698
G V + +G R IQ+ L+ + + + E+ L+ D +GNYVIQ + G
Sbjct: 875 GQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGR 934
Query: 699 PEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
PE + IR +VL LS + V++K + S+ + ++ E+
Sbjct: 935 PEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEV 981
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/117 (27%), Positives = 55/117 (47%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRF 683
++++ GHV++ +DQ+G+ +Q+ ++ + Q + L T +G VIQR
Sbjct: 834 VKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRI 893
Query: 684 FDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELEGSVI 854
+ T EQ + + + QL YG VIQ LE + IV E+ G V+
Sbjct: 894 LEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVL 950
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/102 (25%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ-------CYSLMTDVFG 662
+ +I G V+ +Q + S +++ + +S E++++ E+ Q Y++M D +
Sbjct: 942 VSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYA 1001
Query: 663 NYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQK 788
NYV+Q+ D+ P Q +I+ +IR + L YG ++ K
Sbjct: 1002 NYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAK 1043
>sp|Q80U58|PUM2_MOUSE Pumilio homolog 2
Length = 1066
Score = 171 bits (433), Expect = 2e-42
Identities = 86/139 (61%), Positives = 107/139 (76%), Gaps = 2/139 (1%)
Frame = +3
Query: 453 RSRLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ 632
RSRLLEDFR NR L L+D+ GH+VEF+QDQHGSRFIQQKL+ ++ E+ +VF EIL
Sbjct: 707 RSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQIVFNEILQA 766
Query: 633 CYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKV 812
Y LMTDVFGNYVIQ+FF+ G+ +Q L RIR VL L+LQMYGCRVIQKALE++S
Sbjct: 767 AYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSD 826
Query: 813 TQI--NIVRELEGSVIKCV 863
Q+ +V+EL+G V+KCV
Sbjct: 827 QQVISEMVKELDGHVLKCV 845
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/111 (33%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Frame = +3
Query: 513 ISGHVVEFAQDQHGSRFIQQKLQESSHNEK--SMVFREILPQCYSLMTDVFGNYVIQRFF 686
I GHV+ A +G R IQ+ L+ S +++ S + +E+ + D GN+V+Q+
Sbjct: 799 IRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCI 858
Query: 687 DLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
+ P+ +Q + D + QV LS YGCRVIQ+ LE + + I+ EL
Sbjct: 859 ECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEEL 909
Score = 52.8 bits (125), Expect = 1e-06
Identities = 29/107 (27%), Positives = 51/107 (47%)
Frame = +3
Query: 519 GHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGT 698
G V + +G R IQ+ L+ + + + E+ L+ D +GNYVIQ + G
Sbjct: 875 GQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGR 934
Query: 699 PEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
PE + IR +VL LS + V++K + S+ + ++ E+
Sbjct: 935 PEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEV 981
Score = 52.0 bits (123), Expect = 2e-06
Identities = 32/117 (27%), Positives = 55/117 (47%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRF 683
++++ GHV++ +DQ+G+ +Q+ ++ + Q + L T +G VIQR
Sbjct: 834 VKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRI 893
Query: 684 FDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELEGSVI 854
+ T EQ + + + QL YG VIQ LE + IV E+ G V+
Sbjct: 894 LEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVL 950
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/102 (25%), Positives = 53/102 (51%), Gaps = 7/102 (6%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ-------CYSLMTDVFG 662
+ +I G V+ +Q + S +++ + +S E++++ E+ Q Y++M D +
Sbjct: 942 VSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYA 1001
Query: 663 NYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQK 788
NYV+Q+ D+ P Q +I+ +IR + L YG ++ K
Sbjct: 1002 NYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAK 1043
>sp|Q14671|PUM1_HUMAN Pumilio homolog 1 (Pumilio-1) (HsPUM)
Length = 1186
Score = 169 bits (428), Expect = 9e-42
Identities = 84/137 (61%), Positives = 104/137 (75%)
Frame = +3
Query: 453 RSRLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ 632
RSRLLEDFR NR L L++I+GH++EF+QDQHGSRFIQ KL+ ++ E+ +VF EIL
Sbjct: 829 RSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQA 888
Query: 633 CYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKV 812
Y LM DVFGNYVIQ+FF+ G+ EQ L +RIR VL L+LQMYGCRVIQKALE +
Sbjct: 889 AYQLMVDVFGNYVIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSD 948
Query: 813 TQINIVRELEGSVIKCV 863
Q +VREL+G V+KCV
Sbjct: 949 QQNEMVRELDGHVLKCV 965
Score = 66.2 bits (160), Expect = 1e-10
Identities = 36/109 (33%), Positives = 58/109 (53%)
Frame = +3
Query: 513 ISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDL 692
I GHV+ A +G R IQ+ L+ ++++ + RE+ + D GN+V+Q+ +
Sbjct: 921 IRGHVLSLALQMYGCRVIQKALEFIPSDQQNEMVRELDGHVLKCVKDQNGNHVVQKCIEC 980
Query: 693 GTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
P+ +Q + D + QV LS YGCRVIQ+ LE + I+ EL
Sbjct: 981 VQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPDQTLPILEEL 1029
Score = 53.1 bits (126), Expect = 1e-06
Identities = 31/117 (26%), Positives = 57/117 (48%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRF 683
++++ GHV++ +DQ+G+ +Q+ ++ + Q ++L T +G VIQR
Sbjct: 954 VRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRI 1013
Query: 684 FDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELEGSVI 854
+ P+Q + + + QL YG VIQ LE + IV E+ G+V+
Sbjct: 1014 LEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVL 1070
Score = 50.8 bits (120), Expect = 5e-06
Identities = 29/107 (27%), Positives = 50/107 (46%)
Frame = +3
Query: 519 GHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGT 698
G V + +G R IQ+ L+ ++ + E+ L+ D +GNYVIQ + G
Sbjct: 995 GQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGR 1054
Query: 699 PEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
PE + IR VL LS + V++K + S+ + ++ E+
Sbjct: 1055 PEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEV 1101
Score = 49.7 bits (117), Expect = 1e-05
Identities = 25/100 (25%), Positives = 52/100 (52%), Gaps = 7/100 (7%)
Frame = +3
Query: 510 DISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ-------CYSLMTDVFGNY 668
+I G+V+ +Q + S +++ + +S E++++ E+ Y++M D + NY
Sbjct: 1064 EIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANY 1123
Query: 669 VIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQK 788
V+Q+ D+ P Q +I+ +IR + L YG ++ K
Sbjct: 1124 VVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAK 1163
>sp|Q80U78|PUM1_MOUSE Pumilio homolog 1
Length = 1189
Score = 167 bits (422), Expect = 5e-41
Identities = 84/139 (60%), Positives = 105/139 (75%), Gaps = 2/139 (1%)
Frame = +3
Query: 453 RSRLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ 632
RSRLLEDFR NR L L++I+GH++EF+QDQHGSRFIQ KL+ ++ E+ +VF EIL
Sbjct: 830 RSRLLEDFRNNRYPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATAAERQLVFNEILQA 889
Query: 633 CYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKV 812
Y LM DVFGNYVIQ+FF+ G+ EQ L +RIR VL L+LQMYGCRVIQKALE +
Sbjct: 890 AYQLMVDVFGNYVIQKFFEFGSHEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSD 949
Query: 813 TQI--NIVRELEGSVIKCV 863
Q+ +VREL+G V+KCV
Sbjct: 950 QQVINEMVRELDGHVLKCV 968
Score = 53.1 bits (126), Expect = 1e-06
Identities = 31/117 (26%), Positives = 57/117 (48%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRF 683
++++ GHV++ +DQ+G+ +Q+ ++ + Q ++L T +G VIQR
Sbjct: 957 VRELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRI 1016
Query: 684 FDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELEGSVI 854
+ P+Q + + + QL YG VIQ LE + IV E+ G+V+
Sbjct: 1017 LEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVL 1073
Score = 50.8 bits (120), Expect = 5e-06
Identities = 29/107 (27%), Positives = 50/107 (46%)
Frame = +3
Query: 519 GHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGT 698
G V + +G R IQ+ L+ ++ + E+ L+ D +GNYVIQ + G
Sbjct: 998 GQVFALSTHPYGCRVIQRILEHCLPDQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGR 1057
Query: 699 PEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
PE + IR VL LS + V++K + S+ + ++ E+
Sbjct: 1058 PEDKSKIVAEIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEV 1104
Score = 49.7 bits (117), Expect = 1e-05
Identities = 25/100 (25%), Positives = 52/100 (52%), Gaps = 7/100 (7%)
Frame = +3
Query: 510 DISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ-------CYSLMTDVFGNY 668
+I G+V+ +Q + S +++ + +S E++++ E+ Y++M D + NY
Sbjct: 1067 EIRGNVLVLSQHKFASNVVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANY 1126
Query: 669 VIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQK 788
V+Q+ D+ P Q +I+ +IR + L YG ++ K
Sbjct: 1127 VVQKMIDVAEPGQRKIVMHKIRPHIATLRKYTYGKHILAK 1166
>sp|Q07807|PUF3_YEAST PUF3 protein
Length = 879
Score = 127 bits (318), Expect = 5e-29
Identities = 68/142 (47%), Positives = 91/142 (64%), Gaps = 5/142 (3%)
Frame = +3
Query: 453 RSRLLEDFR-----ANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFR 617
RS LLE R N + ++L+DI GH +EF +DQHGSRFIQ++L S +EK ++F
Sbjct: 514 RSPLLEQLRNSSSDKNSNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIFN 573
Query: 618 EILPQCYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALE 797
EI L DVFGNYVIQ+FF+ G+ Q L D+ + + QLSLQMY CRVIQKALE
Sbjct: 574 EIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALE 633
Query: 798 TVSKVTQINIVRELEGSVIKCV 863
+ +I +V EL SV++ +
Sbjct: 634 YIDSNQRIELVLELSDSVLQMI 655
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/113 (26%), Positives = 56/113 (49%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRF 683
+ G++ + + + R IQ+ L+ N++ + E+ ++ D GN+VIQ+
Sbjct: 608 VDQFKGNMKQLSLQMYACRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKA 667
Query: 684 FDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELE 842
+ E++ + + + LS YGCRVIQ+ LE S Q +I+ EL+
Sbjct: 668 IETIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELK 720
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/113 (25%), Positives = 56/113 (49%)
Frame = +3
Query: 459 RLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCY 638
+ LE +N+ L L+ +S V++ +DQ+G+ IQ+ ++ + + + Y
Sbjct: 630 KALEYIDSNQRIELVLE-LSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSSLTGHIY 688
Query: 639 SLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALE 797
L T +G VIQR + G+ E + + + +++ + L YG VIQ L+
Sbjct: 689 HLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQDQYGNYVIQYVLQ 741
Score = 37.7 bits (86), Expect = 0.042
Identities = 20/90 (22%), Positives = 46/90 (51%), Gaps = 13/90 (14%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ-------------CYSL 644
++ ++ +VVE+++ + S +++ + S N+K ++ +ILP+ +
Sbjct: 758 IETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILM 817
Query: 645 MTDVFGNYVIQRFFDLGTPEQIQILGDRIR 734
+ D F NYVIQ+ ++ E +++ IR
Sbjct: 818 IKDQFANYVIQKLVNVSEGEGKKLIVIAIR 847
>sp|P39016|MPT5_YEAST Suppressor protein MPT5 (HTR1 protein)
Length = 834
Score = 80.9 bits (198), Expect = 4e-15
Identities = 51/177 (28%), Positives = 88/177 (49%), Gaps = 2/177 (1%)
Frame = +3
Query: 306 GNNPTMLGAPQPSHTLMPATGSQLITHQGNKPMQSGYKGVVGNLKDGVTRSRLLEDFRAN 485
G N + L PS ++ PA + ++ N + G L + S +
Sbjct: 126 GVNTSSLIMETPSSSVTPAASLRNFSNSNNAASKCGVDNSSFGLSSSTSSSMV------- 178
Query: 486 RLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNE--KSMVFREILPQCYSLMTDVF 659
++ L L+D+ ++ A DQ G RF+Q+KL+ S + + +++ +I P L+ D F
Sbjct: 179 EISALPLRDLD--YIKLATDQFGCRFLQKKLETPSESNMVRDLMYEQIKPFFLDLILDPF 236
Query: 660 GNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIV 830
GNY++Q+ D T EQ +L I V Q+S+ YG R +QK ++TV QI+++
Sbjct: 237 GNYLVQKLCDYLTAEQKTLLIQTIYPNVFQISINQYGTRSLQKIIDTVDNEVQIDLI 293
Score = 46.6 bits (109), Expect = 9e-05
Identities = 37/132 (28%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Frame = +3
Query: 471 DFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEK---------SMVFREI 623
D+ TL +Q I +V + + +Q+G+R +Q K+ ++ NE S F I
Sbjct: 246 DYLTAEQKTLLIQTIYPNVFQISINQYGTRSLQ-KIIDTVDNEVQIDLIIKGFSQEFTSI 304
Query: 624 LPQCYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRI--RNQVLQLSLQMYGCRVIQKALE 797
Q +L+ D+ GN+VIQ+ +P + + D I +N ++ +S +GC V+QK L
Sbjct: 305 -EQVVTLINDLNGNHVIQKCIFKFSPSKFGFIIDAIVEQNNIITISTHKHGCCVLQKLLS 363
Query: 798 --TVSKVTQINI 827
T+ ++ +I++
Sbjct: 364 VCTLQQIFKISV 375
Score = 38.5 bits (88), Expect = 0.024
Identities = 25/111 (22%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Frame = +3
Query: 522 HVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGTP 701
+++ + +HG +Q+ L + + + +I+ L+ D FGNY+IQ D+
Sbjct: 344 NIITISTHKHGCCVLQKLLSVCTLQQIFKISVKIVQFLPGLINDQFGNYIIQFLLDIKEL 403
Query: 702 E--QIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVRELEGS 848
+ + L +R+ N++ QLS + V++K ++ + ++ IV G+
Sbjct: 404 DFYLLAELFNRLSNELCQLSCLKFSSNVVEKFIKKLFRIITGFIVNNNGGA 454
>sp|Q92359|YDHE_SCHPO Hypothetical protein C6G9.14 in chromosome I
Length = 681
Score = 72.4 bits (176), Expect = 2e-12
Identities = 40/126 (31%), Positives = 72/126 (57%), Gaps = 1/126 (0%)
Frame = +3
Query: 480 ANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVF 659
++ + +L+LQ+ +++ F +DQHG R++Q+ L++ + + VF E P LM D F
Sbjct: 335 SSSVASLSLQN--SNILSFCKDQHGCRYLQRLLEKKNQSHIDAVFAETHPYLAVLMVDAF 392
Query: 660 GNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQIN-IVRE 836
GNY+ Q+ F+ + Q I +++ +S M+G R +QK ++ VS QI+ IV
Sbjct: 393 GNYLCQKLFEHASEAQRSTFIQIIAPKLVPISFNMHGTRALQKIIDLVSSPDQISCIVNA 452
Query: 837 LEGSVI 854
L +V+
Sbjct: 453 LRPNVV 458
Score = 48.1 bits (113), Expect = 3e-05
Identities = 29/102 (28%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQ-ESSHNEKSMVFREILPQCYSLMTDVFGNYVIQR 680
+Q I+ +V + + HG+R +Q+ + SS ++ S + + P L D+ GN+VIQ+
Sbjct: 413 IQIIAPKLVPISFNMHGTRALQKIIDLVSSPDQISCIVNALRPNVVLLTKDLNGNHVIQK 472
Query: 681 FFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVS 806
+ + E Q + D I L +S +GC V+Q+ + S
Sbjct: 473 CLNKFSQEDCQFIFDAICEDPLDVSTHRHGCCVVQRCFDHAS 514
Score = 46.6 bits (109), Expect = 9e-05
Identities = 24/104 (23%), Positives = 48/104 (46%)
Frame = +3
Query: 528 VEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGTPEQ 707
++ + +HG +Q+ +S + + I+P +L+ D FGNYV+Q +L P
Sbjct: 494 LDVSTHRHGCCVVQRCFDHASPAQIEQLVEHIVPHALTLVQDAFGNYVLQYVLELNNPNH 553
Query: 708 IQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
+ + +V LS Q + V++K + + ++ EL
Sbjct: 554 TEAIISYFLYKVRALSTQKFSSNVMEKCIFFAPAAIKEKLISEL 597
>sp|P25339|PUF4_YEAST PUF4 protein
Length = 888
Score = 66.2 bits (160), Expect = 1e-10
Identities = 38/126 (30%), Positives = 61/126 (48%)
Frame = +3
Query: 453 RSRLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQ 632
+ R +E+ ++R L G + +DQHG RF+Q++L +F E
Sbjct: 546 KQRKIEE--SSRFADAVLDQYIGSIHSLCKDQHGCRFLQKQLDILGSKAADAIFEETKDY 603
Query: 633 CYSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALETVSKV 812
LMTD FGNY+IQ+ + T EQ +L +++SL +G R +QK +E +
Sbjct: 604 TVELMTDSFGNYLIQKLLEEVTTEQRIVLTKISSPHFVEISLNPHGTRALQKLIECIKTD 663
Query: 813 TQINIV 830
+ IV
Sbjct: 664 EEAQIV 669
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 1/114 (0%)
Frame = +3
Query: 459 RLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREIL-PQC 635
+LLE+ + LT + S H VE + + HG+R +Q+ ++ +E++ + + L P
Sbjct: 619 KLLEEVTTEQRIVLT-KISSPHFVEISLNPHGTRALQKLIECIKTDEEAQIVVDSLRPYT 677
Query: 636 YSLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKALE 797
L D+ GN+VIQ+ PE Q + D I + + ++ +GC V+Q+ L+
Sbjct: 678 VQLSKDLNGNHVIQKCLQRLKPENFQFIFDAISDSCIDIATHRHGCCVLQRCLD 731
Score = 50.8 bits (120), Expect = 5e-06
Identities = 30/109 (27%), Positives = 53/109 (48%)
Frame = +3
Query: 459 RLLEDFRANRLTTLTLQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCY 638
+L+E + + + + + + V+ ++D +G+ IQ+ LQ +F I C
Sbjct: 655 KLIECIKTDEEAQIVVDSLRPYTVQLSKDLNGNHVIQKCLQRLKPENFQFIFDAISDSCI 714
Query: 639 SLMTDVFGNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRVIQ 785
+ T G V+QR D GT EQ L D++ V +L+L +G V+Q
Sbjct: 715 DIATHRHGCCVLQRCLDHGTTEQCDNLCDKLLALVDKLTLDPFGNYVVQ 763
>sp|Q10238|YD15_SCHPO Putative regulatory protein C4G9.05
Length = 581
Score = 62.4 bits (150), Expect = 2e-09
Identities = 33/102 (32%), Positives = 55/102 (53%)
Frame = +3
Query: 534 FAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDLGTPEQIQ 713
F DQ S +QQ+L+ + + ILP +LM + FGN++IQ+ F+ T Q+Q
Sbjct: 263 FQNDQAASLSLQQQLKNEDIEDNINLINTILPFSVTLMKNKFGNFLIQKCFEYSTEAQLQ 322
Query: 714 ILGDRIRNQVLQLSLQMYGCRVIQKALETVSKVTQINIVREL 839
++ V +LS+ +G V+QK+LE + N++ EL
Sbjct: 323 SFSYFLKKHVKELSIDAFGSHVLQKSLEIYPERFTNNLIEEL 364
Score = 37.4 bits (85), Expect = 0.054
Identities = 20/100 (20%), Positives = 48/100 (48%), Gaps = 8/100 (8%)
Frame = +3
Query: 504 LQDISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREI------LPQCY--SLMTDVF 659
L + V ++ +++ S+ +++ L+ +EI LP + + ++ +
Sbjct: 473 LNSLLKEVESYSTNRYASKVVERALRVCHVTFFDRYVKEITTPQNELPTIFLQEIASNQY 532
Query: 660 GNYVIQRFFDLGTPEQIQILGDRIRNQVLQLSLQMYGCRV 779
GNY++Q + TP QI ++ + ++ ++ L YG R+
Sbjct: 533 GNYIVQYLLQVATPSQINLMAEHLKKHMVSLRGHKYGQRI 572
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/94 (21%), Positives = 43/94 (45%)
Frame = +3
Query: 513 ISGHVVEFAQDQHGSRFIQQKLQESSHNEKSMVFREILPQCYSLMTDVFGNYVIQRFFDL 692
+ G ++ + + GS +Q + +K EI+ ++ +GN+VIQ +
Sbjct: 404 MQGKWLQVSVSEMGSLVVQTIFENCKEKDKRTCLDEIINNMDQIICGQWGNWVIQHIIEH 463
Query: 693 GTPEQIQILGDRIRNQVLQLSLQMYGCRVIQKAL 794
G+ Q + + + +V S Y +V+++AL
Sbjct: 464 GSEPDKQRILNSLLKEVESYSTNRYASKVVERAL 497
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,161,208
Number of Sequences: 369166
Number of extensions: 1832942
Number of successful extensions: 5084
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4705
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5053
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)