Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01910
(859 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35458|DYNA_CHICK Dynactin-1 (150 kDa dynein-associated ... 76 1e-13
sp|Q6PCJ1|DYNA_XENLA Dynactin-1 76 1e-13
sp|Q14203|DYNA_HUMAN Dynactin-1 (150 kDa dynein-associated ... 72 2e-12
sp|O08788|DYNA_MOUSE Dynactin-1 (150 kDa dynein-associated ... 72 2e-12
sp|P28023|DYNA_RAT Dynactin-1 (150 kDa dynein-associated po... 72 2e-12
sp|P13496|DYNA_DROME 150 kDa dynein-associated polypeptide ... 66 1e-10
sp|Q8CI96|RSNL2_MOUSE Restin-like protein 2 63 9e-10
sp|Q8N3C7|RSNL2_HUMAN Restin-like protein 2 63 1e-09
sp|Q66HD5|RSNL2_RAT Restin-like protein 2 63 1e-09
sp|Q01397|DYNA_NEUCR Dynactin, 150 kDa isoform (150 kDa dyn... 62 2e-09
>sp|P35458|DYNA_CHICK Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150)
(DAP-150) (p150-glued)
Length = 1224
Score = 76.3 bits (186), Expect = 1e-13
Identities = 41/95 (43%), Positives = 57/95 (60%), Gaps = 1/95 (1%)
Frame = +1
Query: 169 NKQTSNSNAKDLKPKISS-INSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVG 345
+++ + A P++S+ +S+ LK+GSRV I G+ TV Y +T TG WVG
Sbjct: 4 SRRHPHGRASSAGPRMSTEASSKPLKVGSRVEVI---GKGHRGTVAYVGATLXATGKWVG 60
Query: 346 LELDENKGNHNGTVDGVKYFTCAHNHGIFTRPDNV 450
+ LDE KG ++GTV G KYFTC NHGIF R +
Sbjct: 61 VILDEAKGKNDGTVQGRKYFTCEENHGIFVRQSQI 95
>sp|Q6PCJ1|DYNA_XENLA Dynactin-1
Length = 1232
Score = 76.3 bits (186), Expect = 1e-13
Identities = 36/75 (48%), Positives = 49/75 (65%)
Frame = +1
Query: 238 LKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYFTCAH 417
LK+GSRV I G+ TV Y +T F TG WVG+ LD++KG ++GTV G +YFTC
Sbjct: 10 LKVGSRVEVI---GKGYRGTVAYVGATLFATGKWVGVILDDSKGKNDGTVQGRRYFTCEE 66
Query: 418 NHGIFTRPDNVFIVK 462
NHGIF R + +++
Sbjct: 67 NHGIFVRQSQIQVIE 81
>sp|Q14203|DYNA_HUMAN Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150)
(DAP-150) (p150-glued) (p135)
Length = 1278
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/75 (48%), Positives = 47/75 (62%)
Frame = +1
Query: 226 NSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYF 405
+++ L++GSRV I G+ TV Y +T F TG WVG+ LDE KG ++GTV G KYF
Sbjct: 23 SARPLRVGSRVEVI---GKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYF 79
Query: 406 TCAHNHGIFTRPDNV 450
TC HGIF R +
Sbjct: 80 TCDEGHGIFVRQSQI 94
>sp|O08788|DYNA_MOUSE Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150)
(DAP-150) (p150-glued)
Length = 1281
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/75 (48%), Positives = 47/75 (62%)
Frame = +1
Query: 226 NSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYF 405
+++ L++GSRV I G+ TV Y +T F TG WVG+ LDE KG ++GTV G KYF
Sbjct: 23 SARPLRVGSRVEVI---GKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYF 79
Query: 406 TCAHNHGIFTRPDNV 450
TC HGIF R +
Sbjct: 80 TCDEGHGIFVRQSQI 94
>sp|P28023|DYNA_RAT Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150)
(DAP-150) (p150-glued)
Length = 1280
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/75 (48%), Positives = 47/75 (62%)
Frame = +1
Query: 226 NSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYF 405
+++ L++GSRV I G+ TV Y +T F TG WVG+ LDE KG ++GTV G KYF
Sbjct: 23 SARPLRVGSRVEVI---GKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYF 79
Query: 406 TCAHNHGIFTRPDNV 450
TC HGIF R +
Sbjct: 80 TCDEGHGIFVRQSQI 94
>sp|P13496|DYNA_DROME 150 kDa dynein-associated polypeptide (DP-150) (DAP-150) (Glued
protein)
Length = 1265
Score = 65.9 bits (159), Expect = 1e-10
Identities = 31/80 (38%), Positives = 49/80 (61%)
Frame = +1
Query: 223 INSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKY 402
++ ++LK+G+RV G+ L TV Y T F G WVG+ LDE KG ++G++ G +Y
Sbjct: 1 MSEKNLKVGARVELT---GKDLLGTVAYVGMTSFAVGKWVGVVLDEPKGKNSGSIKGQQY 57
Query: 403 FTCAHNHGIFTRPDNVFIVK 462
F C N G+F RP + +++
Sbjct: 58 FQCDENCGMFVRPTQLRLLE 77
>sp|Q8CI96|RSNL2_MOUSE Restin-like protein 2
Length = 704
Score = 63.2 bits (152), Expect = 9e-10
Identities = 36/106 (33%), Positives = 53/106 (50%), Gaps = 15/106 (14%)
Frame = +1
Query: 178 TSNSNAKDLK--PKISSINSQSLKIGSRVSTINSHGETLY-------------ATVKYFN 312
TS+ K L P + S S LK + + NSH E T+K+F
Sbjct: 445 TSSGGKKTLSKSPSLPSRASAGLKSSATSAANNSHHEGALHLGERVLVVGQRVGTIKFFG 504
Query: 313 STQFETGIWVGLELDENKGNHNGTVDGVKYFTCAHNHGIFTRPDNV 450
+T F G W G+EL++ G ++G+V GV+YF+C+ +GIF P V
Sbjct: 505 TTNFAPGYWYGIELEKPHGKNDGSVGGVQYFSCSPRYGIFAPPSRV 550
Score = 60.8 bits (146), Expect = 5e-09
Identities = 26/53 (49%), Positives = 34/53 (64%)
Frame = +1
Query: 292 ATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYFTCAHNHGIFTRPDNV 450
ATV+Y T F +GIW+GLEL KG ++G V +YFTC N+G+ RP V
Sbjct: 637 ATVRYVGPTDFASGIWLGLELRSAKGKNDGAVGDKRYFTCKPNYGVLVRPSRV 689
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/70 (40%), Positives = 42/70 (60%)
Frame = +1
Query: 223 INSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKY 402
+ S LK+G RV T+++ +T+F +G W G+ELDE +G +NG+V V+Y
Sbjct: 278 LTSLGLKLGDRVVIAGQK----VGTLRFCGTTEFASGQWAGIELDEPEGKNNGSVGRVQY 333
Query: 403 FTCAHNHGIF 432
F CA +GIF
Sbjct: 334 FKCAPKYGIF 343
>sp|Q8N3C7|RSNL2_HUMAN Restin-like protein 2
Length = 705
Score = 62.8 bits (151), Expect = 1e-09
Identities = 32/74 (43%), Positives = 43/74 (58%)
Frame = +1
Query: 229 SQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYFT 408
S L GS+V +S+ TV+Y T F +GIW+GLEL KG ++G+V +YFT
Sbjct: 620 SVKLHEGSQVLLTSSNE---MGTVRYVGPTDFASGIWLGLELRSAKGKNDGSVGDKRYFT 676
Query: 409 CAHNHGIFTRPDNV 450
C NHG+ RP V
Sbjct: 677 CKPNHGVLVRPSRV 690
Score = 62.0 bits (149), Expect = 2e-09
Identities = 36/111 (32%), Positives = 58/111 (52%), Gaps = 17/111 (15%)
Frame = +1
Query: 169 NKQTSNSNAKDLKPKISS-----INSQS------------LKIGSRVSTINSHGETLYAT 297
N +SN P +SS +NS + L++G RV + G+ L T
Sbjct: 445 NAISSNKKTMSKSPSLSSRASAGLNSSATSTANNSRCEGELRLGERVLVV---GQRL-GT 500
Query: 298 VKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYFTCAHNHGIFTRPDNV 450
+++F +T F G W G+EL++ G ++G+V GV+YF+C+ +GIF P V
Sbjct: 501 IRFFGTTNFAPGYWYGIELEKPHGKNDGSVGGVQYFSCSPRYGIFAPPSRV 551
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/70 (40%), Positives = 42/70 (60%)
Frame = +1
Query: 223 INSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKY 402
+ S LK+G RV T+++ +T+F +G W G+ELDE +G +NG+V V+Y
Sbjct: 278 LTSLGLKLGDRVVIAGQK----VGTLRFCGTTEFASGQWAGIELDEPEGKNNGSVGKVQY 333
Query: 403 FTCAHNHGIF 432
F CA +GIF
Sbjct: 334 FKCAPKYGIF 343
>sp|Q66HD5|RSNL2_RAT Restin-like protein 2
Length = 599
Score = 62.8 bits (151), Expect = 1e-09
Identities = 27/72 (37%), Positives = 44/72 (61%)
Frame = +1
Query: 235 SLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYFTCA 414
+L++G RV + T+K+F +T F G W G+EL++ G ++G+V GV+YF+C+
Sbjct: 484 ALRLGERVLVVGQR----VGTIKFFGTTNFAPGYWYGIELEKPHGKNDGSVGGVQYFSCS 539
Query: 415 HNHGIFTRPDNV 450
+GIF P V
Sbjct: 540 PRYGIFAPPSRV 551
Score = 59.3 bits (142), Expect = 1e-08
Identities = 30/88 (34%), Positives = 48/88 (54%)
Frame = +1
Query: 199 DLKPKISSINSQSLKIGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHN 378
D+ + + + LK+G RV T+++ +T+F +G W G+ELDE +G +N
Sbjct: 270 DITTSKAMLTTLGLKLGDRVVIAGQK----VGTLRFCGTTEFASGQWAGIELDEPEGKNN 325
Query: 379 GTVDGVKYFTCAHNHGIFTRPDNVFIVK 462
G+V V+YF CA +GIF + VK
Sbjct: 326 GSVGRVQYFKCAPKYGIFAPLSKITKVK 353
>sp|Q01397|DYNA_NEUCR Dynactin, 150 kDa isoform (150 kDa dynein-associated polypeptide)
(DP-150) (DAP-150) (p150-glued)
Length = 1300
Score = 62.0 bits (149), Expect = 2e-09
Identities = 26/66 (39%), Positives = 39/66 (59%)
Frame = +1
Query: 244 IGSRVSTINSHGETLYATVKYFNSTQFETGIWVGLELDENKGNHNGTVDGVKYFTCAHNH 423
+G ++ + G T + V+Y T F G WVG+ELDE G ++G+V G +YF C +
Sbjct: 8 VGQKIELADGSGRTAF--VRYVGETAFAPGTWVGIELDEPSGKNDGSVQGERYFNCEMGY 65
Query: 424 GIFTRP 441
G+F RP
Sbjct: 66 GMFVRP 71
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,505,333
Number of Sequences: 369166
Number of extensions: 1611626
Number of successful extensions: 4074
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3927
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4060
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8486520240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)