Planaria EST Database


DrC_01900

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01900
         (849 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P46941|YLE5_CAEEL  Hypothetical protein C38D4.5 in chromo...   114   4e-25
sp|Q8IWW6|RHG12_HUMAN  Rho-GTPase-activating protein 12           108   2e-23
sp|Q8C0D4|RHG12_MOUSE  Rho-GTPase-activating protein 12           108   2e-23
sp|Q9BE31|RHG12_MACFA  Rho-GTPase-activating protein 12           107   3e-23
sp|Q9BRR9|RHG09_HUMAN  Rho-GTPase-activating protein 9            105   1e-22
sp|P52757|CHIO_HUMAN  Beta-chimaerin (Beta-chimerin) (Rho-GT...    73   1e-12
sp|P15882|CHIN_HUMAN  N-chimaerin (NC) (N-chimerin) (Alpha c...    70   6e-12
sp|P30337|CHIN_RAT  N-chimaerin (NC) (N-chimerin) (Alpha chi...    70   6e-12
sp|Q91V57|CHIN_MOUSE  N-chimaerin (NC) (N-chimerin) (Alpha c...    70   7e-12
sp|Q80XD1|CHIO_MOUSE  Beta-chimaerin (Beta-chimerin) (Rho-GT...    70   1e-11
>sp|P46941|YLE5_CAEEL Hypothetical protein C38D4.5 in chromosome III
          Length = 837

 Score =  114 bits (284), Expect = 4e-25
 Identities = 64/202 (31%), Positives = 109/202 (53%)
 Frame = +2

Query: 14   LKQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHS 193
            L++F + RP+ ESL+ +GI KPE VFGS+L  +C+ E + +P+F+      IE++GL   
Sbjct: 583  LRRFFRTRPTVESLKEKGIYKPEPVFGSTLSAICQHENSLVPKFIRVITEVIESKGLETD 642

Query: 194  GIYRVSGNQAKIQKLRLAVDENKYQLNSEFMELETLTGAXXXXXXXXXXXXXXXXXCAKL 373
            GIYRVSGN + +QK+R   D++ Y+      ++  LTGA                   + 
Sbjct: 643  GIYRVSGNLSAVQKIRCQADQDNYKALVSEEDIHVLTGALKLFFRELTDPLFPISLHKEY 702

Query: 374  IDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMDIG 553
               +    A  +           ++L++++   + ET K L  HL++VA+HSS+N M   
Sbjct: 703  TSAMQMPNATTR-------FKKFEELLSRLPNENRETLKMLLRHLNRVASHSSQNRMQQH 755

Query: 554  NISMVWGPNLYSSTGQASTKMA 619
            N+++V+GP L+ + G  +  +A
Sbjct: 756  NLAIVFGPTLFHN-GDGAVNLA 776
>sp|Q8IWW6|RHG12_HUMAN Rho-GTPase-activating protein 12
          Length = 846

 Score =  108 bits (270), Expect = 2e-23
 Identities = 72/225 (32%), Positives = 116/225 (51%), Gaps = 2/225 (0%)
 Frame = +2

Query: 14   LKQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHS 193
            LK+FL  RP+ +++  +G +K + VFGS+L  LC++E   +P+FV  CI  +E  GL   
Sbjct: 630  LKKFLTRRPTLQAVREKGYIKDQ-VFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDID 688

Query: 194  GIYRVSGNQAKIQKLRLAVD-ENKYQLN-SEFMELETLTGAXXXXXXXXXXXXXXXXXCA 367
            GIYRVSGN A IQKLR AV+ + K  LN S++ ++  +TGA                   
Sbjct: 689  GIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748

Query: 368  KLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMD 547
              ++ +      +    KD        LI ++   + +T + LF HL +V  +  KN M 
Sbjct: 749  DFVNAIKQEPRQRVAAVKD--------LIRQLPKPNQDTMQILFRHLRRVIENGEKNRMT 800

Query: 548  IGNISMVWGPNLYSSTGQASTKMAVLLMTHNQIIDFLITRYSDLF 682
              +I++V+GP L     +    +AV  +  NQI++ ++   S +F
Sbjct: 801  YQSIAIVFGPTLLKPEKETG-NIAVHTVYQNQIVELILLELSSIF 844
>sp|Q8C0D4|RHG12_MOUSE Rho-GTPase-activating protein 12
          Length = 838

 Score =  108 bits (269), Expect = 2e-23
 Identities = 72/225 (32%), Positives = 116/225 (51%), Gaps = 2/225 (0%)
 Frame = +2

Query: 14   LKQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHS 193
            LK+FL  RP+ +++  +G +K + VFGS+L  LC++E   +P+FV  CI  +E  GL   
Sbjct: 622  LKKFLTRRPTLQAVREKGYIKDQ-VFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVD 680

Query: 194  GIYRVSGNQAKIQKLRLAVD-ENKYQLN-SEFMELETLTGAXXXXXXXXXXXXXXXXXCA 367
            GIYRVSGN A IQKLR AV+ + K  LN S++ ++  +TGA                   
Sbjct: 681  GIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 740

Query: 368  KLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMD 547
              ++ +      +    KD        LI ++   + +T + LF HL +V  +  KN M 
Sbjct: 741  DFVNAIKQEPRQRVTAVKD--------LIRQLPKPNQDTMQILFRHLKRVIENGEKNRMT 792

Query: 548  IGNISMVWGPNLYSSTGQASTKMAVLLMTHNQIIDFLITRYSDLF 682
              +I++V+GP L     +    +AV  +  NQI++ ++   S +F
Sbjct: 793  YQSIAIVFGPTLLKPERETG-NIAVHTVYQNQIVELILLELSTVF 836
>sp|Q9BE31|RHG12_MACFA Rho-GTPase-activating protein 12
          Length = 847

 Score =  107 bits (268), Expect = 3e-23
 Identities = 72/225 (32%), Positives = 116/225 (51%), Gaps = 2/225 (0%)
 Frame = +2

Query: 14   LKQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHS 193
            LK+FL  RP+ +++  +G +K + VFGS+L  LC++E   +P+FV  CI  +E  GL   
Sbjct: 631  LKKFLTRRPTLQAVREKGYIKDQ-VFGSNLANLCQRENGTVPKFVKLCIEHVEEYGLDVD 689

Query: 194  GIYRVSGNQAKIQKLRLAVD-ENKYQLN-SEFMELETLTGAXXXXXXXXXXXXXXXXXCA 367
            GIYRVSGN A IQKLR AV+ + K  LN S++ ++  +TGA                   
Sbjct: 690  GIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 749

Query: 368  KLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMD 547
              ++ +      +    KD        LI ++   + +T + LF HL +V  +  KN M 
Sbjct: 750  DFVNAIKQEPRQRVAAVKD--------LIRQLPKPNQDTMQILFRHLKRVVENGEKNRMT 801

Query: 548  IGNISMVWGPNLYSSTGQASTKMAVLLMTHNQIIDFLITRYSDLF 682
              +I++V+GP L     +    +AV  +  NQI++ ++   S +F
Sbjct: 802  YQSIAIVFGPTLLKPEKETG-NIAVHTVYQNQIVELILLELSSIF 845
>sp|Q9BRR9|RHG09_HUMAN Rho-GTPase-activating protein 9
          Length = 750

 Score =  105 bits (263), Expect = 1e-22
 Identities = 76/243 (31%), Positives = 120/243 (49%), Gaps = 20/243 (8%)
 Frame = +2

Query: 14   LKQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHS 193
            LK+ +  RP  +SL+ RG+L+ + VFG  LE LC++E + +P F+  CI A++ RGL   
Sbjct: 516  LKRLIAKRPPLQSLQERGLLRDQ-VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD 574

Query: 194  GIYRVSGNQAKIQKLRLAVD-------------------ENKYQLNS-EFMELETLTGAX 313
            GIYRVSGN A +QKLR  VD                   E +  L+S E+ ++  +TGA 
Sbjct: 575  GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL 634

Query: 314  XXXXXXXXXXXXXXXXCAKLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKA 493
                                  LL   +A    +  +  ++  ++LI  M   +++T + 
Sbjct: 635  KLFLRELPQPLVPPL-------LLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRY 687

Query: 494  LFGHLHKVAAHSSKNYMDIGNISMVWGPNLYSSTGQASTKMAVLLMTHNQIIDFLITRYS 673
            L  HL +V AHS KN M   N+ +V+GP L+    + S   A  L    Q++  ++T ++
Sbjct: 688  LLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYP-GQLVQLMLTNFT 746

Query: 674  DLF 682
             LF
Sbjct: 747  SLF 749
>sp|P52757|CHIO_HUMAN Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3)
          Length = 468

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 3/202 (1%)
 Frame = +2

Query: 86  VFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHSGIYRVSGNQAKIQKLRLAVDENKY 265
           V+   L  L +    + P  V  CI  IEARGL   G+YRVSG    I+ +++A D +  
Sbjct: 274 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 333

Query: 266 QLN---SEFMELETLTGAXXXXXXXXXXXXXXXXXCAKLIDLLSSRKADKKNTYKDININ 436
           + +   + + ++  +TGA                  +K ID      AD++       + 
Sbjct: 334 KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADER-------LE 386

Query: 437 TAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMDIGNISMVWGPNLYSSTGQASTKM 616
              +++  + P+HYET + L  HL KV  +   N+M+  N+ +V+GP L      ++   
Sbjct: 387 AVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTT 446

Query: 617 AVLLMTHNQIIDFLITRYSDLF 682
              +     I+  LI     LF
Sbjct: 447 LHDMRYQKLIVQILIENEDVLF 468
>sp|P15882|CHIN_HUMAN N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin)
           (Rho-GTPase-activating protein 2)
          Length = 459

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 53/195 (27%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
 Frame = +2

Query: 17  KQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHSG 196
           KQ  K+ P+    + + + K   V+   L  L +    K P  V  CI  IE+RGL+  G
Sbjct: 245 KQCSKMVPNDCKPDLKHVKK---VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEG 301

Query: 197 IYRVSGNQAKIQKLRLAVDENKYQLN---SEFMELETLTGAXXXXXXXXXXXXXXXXXCA 367
           +YRVSG    I+ +++A D +  + +   + + ++  +TGA                   
Sbjct: 302 LYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYP 361

Query: 368 KLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMD 547
           K I+  S++  D      D  + T  + +  + P+H ET + L  HL +V  H  +N M+
Sbjct: 362 KFIE--SAKIMD-----PDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMN 414

Query: 548 IGNISMVWGPNLYSS 592
             N+ +V+GP L  S
Sbjct: 415 AENLGIVFGPTLMRS 429
>sp|P30337|CHIN_RAT N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin)
           (Rho-GTPase-activating protein 2)
          Length = 334

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
 Frame = +2

Query: 17  KQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHSG 196
           KQ  K+ P+    + + + K   V+   L  L +    K P  V  CI  IE+RGL+  G
Sbjct: 120 KQCSKMVPNDCKPDLKHVKK---VYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEG 176

Query: 197 IYRVSGNQAKIQKLRLAVDENKYQLN---SEFMELETLTGAXXXXXXXXXXXXXXXXXCA 367
           +YRVSG    I+ +++A D +  + +   + + ++  +TGA                   
Sbjct: 177 LYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYP 236

Query: 368 KLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMD 547
           K I+  S++  D      D  + T  + +  + P+H ET + L  HL +V  H  +N M 
Sbjct: 237 KFIE--SAKIVDP-----DEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMS 289

Query: 548 IGNISMVWGPNLYSS 592
             N+ +V+GP L  S
Sbjct: 290 AENLGIVFGPTLMRS 304
>sp|Q91V57|CHIN_MOUSE N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin)
           (Rho-GTPase-activating protein 2)
          Length = 334

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 51/195 (26%), Positives = 87/195 (44%), Gaps = 3/195 (1%)
 Frame = +2

Query: 17  KQFLKIRPSPESLEARGILKPEAVFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHSG 196
           KQ  K+ P+    + + + K   V+   L  L +    K P  V  CI  IE+RGL+  G
Sbjct: 120 KQCSKMVPNDCKPDLKHVKK---VYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEG 176

Query: 197 IYRVSGNQAKIQKLRLAVDENKYQLN---SEFMELETLTGAXXXXXXXXXXXXXXXXXCA 367
           +YRVSG    I+ +++A D +  + +   + + ++  +TGA                   
Sbjct: 177 LYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYP 236

Query: 368 KLIDLLSSRKADKKNTYKDININTAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMD 547
           K I+       D++       + T  + +  + P+H ET + L  HL +V  H  +N M 
Sbjct: 237 KFIESAKIMDPDEQ-------LETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMS 289

Query: 548 IGNISMVWGPNLYSS 592
             N+ +V+GP L  S
Sbjct: 290 AENLGIVFGPTLMRS 304
>sp|Q80XD1|CHIO_MOUSE Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3)
          Length = 332

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 3/202 (1%)
 Frame = +2

Query: 86  VFGSSLEILCEQEKNKIPEFVYRCILAIEARGLHHSGIYRVSGNQAKIQKLRLAVDEN-- 259
           V+   L  L +    + P  V  CI  IEARGL   G+YRVSG    I+ +++A D +  
Sbjct: 138 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 197

Query: 260 KYQLNSE-FMELETLTGAXXXXXXXXXXXXXXXXXCAKLIDLLSSRKADKKNTYKDININ 436
           K  +++  + ++  +TGA                  +K I+      AD++       + 
Sbjct: 198 KADISANIYPDINIITGALKLYFRDLPIPIITYDTYSKFIEAAKISNADER-------LE 250

Query: 437 TAKKLITKMKPSHYETGKALFGHLHKVAAHSSKNYMDIGNISMVWGPNLYSSTGQASTKM 616
              +++  + P+HYET + L  HL KV  +   N M+  N+ +V+GP L      ++   
Sbjct: 251 AVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTT 310

Query: 617 AVLLMTHNQIIDFLITRYSDLF 682
              +     I+  LI     LF
Sbjct: 311 LHDMRYQKLIVQILIENEDVLF 332
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,294,363
Number of Sequences: 369166
Number of extensions: 1616012
Number of successful extensions: 4049
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3866
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4015
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)