Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01841
(886 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P35556|FBN2_HUMAN Fibrillin-2 precursor 144 4e-34
sp|Q61555|FBN2_MOUSE Fibrillin-2 precursor 141 2e-33
sp|P35555|FBN1_HUMAN Fibrillin-1 precursor 139 1e-32
sp|P98133|FBN1_BOVIN Fibrillin-1 precursor (MP340) 138 2e-32
sp|Q9TV36|FBN1_PIG Fibrillin-1 precursor 137 5e-32
sp|Q61554|FBN1_MOUSE Fibrillin-1 precursor 136 7e-32
sp|O77469|FBLN1_CAEEL Fibulin-1 precursor 134 3e-31
sp|Q75N90|FBN3_HUMAN Fibrillin-3 precursor 134 3e-31
sp|Q8CG18|LTB1S_MOUSE Latent transforming growth factor bet... 131 3e-30
sp|Q8CG19|LTB1L_MOUSE Latent transforming growth factor bet... 131 3e-30
>sp|P35556|FBN2_HUMAN Fibrillin-2 precursor
Length = 2911
Score = 144 bits (362), Expect = 4e-34
Identities = 77/232 (33%), Positives = 108/232 (46%)
Frame = +1
Query: 115 YYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCD 294
+++ C GRCI + YRCEC + D G D
Sbjct: 499 HHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCI----------------------DVD 536
Query: 295 KFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGS 474
+ S C NG C+ + SY CKC+ GFQ + + C DIDEC N +C G C+NS GS
Sbjct: 537 ECTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGS 596
Query: 475 YQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQ 654
+QC C GF + G C D +EC+ ++C NG+CIN GSFKC C G+V + N +
Sbjct: 597 FQCICNAGFEL--TTDGKNCVDHDECT-TTNMCLNGMCINEDGSFKCICKPGFVLAPNGR 653
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
C + D + N +C G+F+C CP G+ +D +C
Sbjct: 654 YCTDV-DECQTPGICMNG--------HCINSEGSFRCDCPPGLAVGMDGRVC 696
Score = 140 bits (353), Expect = 5e-33
Identities = 77/226 (34%), Positives = 98/226 (43%)
Frame = +1
Query: 103 CSFSYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLK 282
CS S C+ G+C+NM Y+C C P + Q C D +
Sbjct: 1203 CSLS--DNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGC-----------TDIDECMIMN 1249
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCIN 462
CD +C S SYEC C+ G+ DG+ C+DIDEC NP ICD G C N
Sbjct: 1250 GGCDT---------QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTN 1300
Query: 463 SPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
PG Y+C CYDGF C D NEC + ++C G C N GSF C C GY
Sbjct: 1301 IPGEYRCLCYDGFMA--SMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVK 1358
Query: 643 SNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
C +D + + C + C + G+FKCSC G
Sbjct: 1359 KGTTGC------TDVDECEIGAHNCDMHAS-CLNIPGSFKCSCREG 1397
Score = 136 bits (342), Expect = 9e-32
Identities = 73/229 (31%), Positives = 106/229 (46%), Gaps = 1/229 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C N ++C C F LD + + C E +
Sbjct: 1083 CTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECR-------------------ISPD 1123
Query: 310 LCKNGRCIESGSSYECKCNLGFQES-SDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
LC +G C+ + S+EC+C G++ K C DID C NP +C GTC+N+ GS+QC
Sbjct: 1124 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCD 1183
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G + P C D NECS +LC+NG C+N+ G+++C CN GY A+ ++Q C
Sbjct: 1184 CPLGHELS--PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTD 1241
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCA 813
I D+ C C G+++CSC G + D CA
Sbjct: 1242 I---------DECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCA 1281
Score = 130 bits (328), Expect = 4e-30
Identities = 71/214 (33%), Positives = 95/214 (44%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N Y C C P F L ND +C F
Sbjct: 1942 CGNGTCKNTVGSYNCLCYPGFELTHN---------------NDCLDI----DECSSFFGQ 1982
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+C+NGRC S++C CN G++ + DGK C D +EC P C GTC N GS++C C
Sbjct: 1983 VCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCIC 2042
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
G+ + + C D NEC ED ++C G C N G F+C C G+V S N + C
Sbjct: 2043 PPGYEVKS----ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDT 2098
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
+ S ++ ++ KCS AF KC C
Sbjct: 2099 RQSFCFTNFEN-----GKCSVPKAFNTTKAKCCC 2127
Score = 129 bits (324), Expect = 1e-29
Identities = 59/176 (33%), Positives = 96/176 (54%)
Frame = +1
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCIN 462
++C F +C G+C + S++C+CN GF + + C+DIDEC +P +C G C+N
Sbjct: 1074 NECKAFPG-MCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVN 1132
Query: 463 SPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
+PGS++C C++G+ M C D + C + LC+ G C+N GSF+C C G+ S
Sbjct: 1133 TPGSFECECFEGYESGFMM-MKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1191
Query: 643 SNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+++DC+ I + S + N K C + GT++CSC G ++ D C
Sbjct: 1192 PSREDCVDINECSLSDNLCRNGK--------CVNMIGTYQCSCNPGYQATPDRQGC 1239
Score = 122 bits (307), Expect = 1e-27
Identities = 80/294 (27%), Positives = 111/294 (37%), Gaps = 67/294 (22%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
CK GRC+N ++C C F L G+ C E M
Sbjct: 585 CKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNM------------------- 625
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQC-- 483
C NG CI S++C C GF + +G+ C+D+DEC T P IC G CINS GS++C
Sbjct: 626 -CLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDC 683
Query: 484 --------------------SCYDGFT----IHNMPG----------------GPKCY-- 537
+CY G + PG G C
Sbjct: 684 PPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPC 743
Query: 538 -----------------------DRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSN 648
D NEC+ D +C NG+C N+ GS++C CNSGY ++
Sbjct: 744 PAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDAS 803
Query: 649 KQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
++CI I + + DN C G++ C+CP G +T C
Sbjct: 804 GRNCIDIDECLVNRLLCDNG--------LCRNTPGSYSCTCPPGYVFRTETETC 849
Score = 120 bits (300), Expect = 7e-27
Identities = 73/266 (27%), Positives = 115/266 (43%), Gaps = 31/266 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF-GS 306
C GG+C N+ +YRC C F+ + C E D S+ + +C+ GS
Sbjct: 1293 CDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNEC------DLNSNICMFGECENTKGS 1346
Query: 307 FLCK-----------------------------NGRCIESGSSYECKCNLGFQESSDGKI 399
F+C + C+ S++C C G+ +G
Sbjct: 1347 FICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGW--IGNGIK 1404
Query: 400 CSDIDECTTNPTICD-RGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCK 576
C D+DEC+ C C+N+PGSY+C+C +GFT G C D +EC+E+ +LC+
Sbjct: 1405 CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFT----GDGFTCSDVDECAENINLCE 1460
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT 756
NG C+N+ G+++C+C G+ +S+ + C I + S + S C + G
Sbjct: 1461 NGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC---------VSGTCNNLPGM 1511
Query: 757 FKCSCPYGMESILDTGLCAPNSQIVD 834
F C C G E G C + D
Sbjct: 1512 FHCICDDGYELDRTGGNCTDIDECAD 1537
Score = 119 bits (297), Expect = 1e-26
Identities = 56/160 (35%), Positives = 86/160 (53%), Gaps = 1/160 (0%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGT-CINSPGSYQCS 486
+C NG CI S+ C+C GF + +C DIDEC+ +C R CINSPGSY+C
Sbjct: 1817 ICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 1876
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C GF + P G C DRNEC E ++C +G+C+++ GS++C C++G+ AS ++ C+
Sbjct: 1877 CAAGFKLS--PNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMD 1933
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
+ + + + C G++ C C G E
Sbjct: 1934 VDECERHPCGNGT----------CKNTVGSYNCLCYPGFE 1963
Score = 115 bits (289), Expect = 1e-25
Identities = 74/235 (31%), Positives = 101/235 (42%), Gaps = 1/235 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN +RCEC F + C+ E C +
Sbjct: 1818 CANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDE------------------CSNGDNL 1859
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+N CI S SY C+C GF+ S +G C D +EC P +C G C++ GSYQC C
Sbjct: 1860 CQRNADCINSPGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCIC 1918
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
++GF C D +EC ++ C NG C N GS+ C C G+ + N DC+ I
Sbjct: 1919 HNGFKASQ--DQTMCMDVDEC--ERHPCGNGTCKNTVGSYNCLCYPGFELTHN-NDCLDI 1973
Query: 670 QD-SSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIV 831
+ SS + V N + C G+FKC C G E D C ++ V
Sbjct: 1974 DECSSFFGQVCRNGR--------CFNEIGSFKCLCNEGYELTPDGKNCIDTNECV 2020
Score = 115 bits (287), Expect = 2e-25
Identities = 65/206 (31%), Positives = 90/206 (43%), Gaps = 28/206 (13%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+CIN +RCEC + LD G C E + N+ GSF
Sbjct: 2181 CSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNV------IGSF 2234
Query: 310 LCKNG--------------------------RCIESGSSYECKCNLGFQESSDGKICSDI 411
C RC+ + SYEC C +G+ D K+C D+
Sbjct: 2235 ECNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKDL 2294
Query: 412 DECTTNPTICD-RGT-CINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGV 585
DEC C+ RG C N G++ C C G P G C D NEC +C+NG
Sbjct: 2295 DECAEGLHDCESRGMMCKNLIGTFMCICPPGMA--RRPDGEGCVDENECRTKPGICENGR 2352
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCI 663
C+NI GS++C+CN G+ +SS+ +C+
Sbjct: 2353 CVNIIGSYRCECNEGFQSSSSGTECL 2378
Score = 114 bits (285), Expect = 4e-25
Identities = 76/265 (28%), Positives = 102/265 (38%), Gaps = 51/265 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQAC----KKRTEY-------------------- 237
C G CIN + +RC+C P + G+ C + T Y
Sbjct: 667 CMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSE 726
Query: 238 -----------KPNQMNDAASSFNLKSQCDK---------------FGSFLCKNGRCIES 339
+P Q A +S C +C NG C
Sbjct: 727 CCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENL 786
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
SY C CN G++ + G+ C DIDEC N +CD G C N+PGSY C+C G+
Sbjct: 787 RGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTET 846
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVD 699
C D NEC + + C NG C N GSF C+C+ G SS CI + + +
Sbjct: 847 --ETCEDINEC--ESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQ 902
Query: 700 DNSKYCSKCSHYCAFVNG-TFKCSC 771
D S+C +NG T K C
Sbjct: 903 D-----SRCE---VNINGATLKSEC 919
Score = 113 bits (282), Expect = 8e-25
Identities = 70/241 (29%), Positives = 104/241 (43%), Gaps = 23/241 (9%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKK--RTEYKPNQMNDAASSFNL----K 282
S C G C N K + C C + + K C E + + AS N+ K
Sbjct: 1332 SNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFK 1391
Query: 283 SQCDKF----------------GSFLCK-NGRCIESGSSYECKCNLGFQESSDGKICSDI 411
C + G+ C N +C+ + SY C C+ GF + DG CSD+
Sbjct: 1392 CSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSDV 1449
Query: 412 DECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCI 591
DEC N +C+ G C+N PG+Y+C C GFT C D +ECS +++C +G C
Sbjct: 1450 DECAENINLCENGQCLNVPGAYRCECEMGFT--PASDSRSCQDIDECS-FQNICVSGTCN 1506
Query: 592 NIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
N+ G F C C+ GY +C I + +D + + C G ++C+C
Sbjct: 1507 NLPGMFHCICDDGYELDRTGGNCTDIDECAD---------PINCVNGLCVNTPGRYECNC 1557
Query: 772 P 774
P
Sbjct: 1558 P 1558
Score = 111 bits (277), Expect = 3e-24
Identities = 82/305 (26%), Positives = 108/305 (35%), Gaps = 88/305 (28%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFNL--KS 285
C+ GRC+N+ YRCEC F G C E A+SS NL KS
Sbjct: 2348 CENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKS 2407
Query: 286 QCDKFGSF------------------------------------------LCKNGRCIES 339
+C G LC NG+CI +
Sbjct: 2408 ECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINT 2467
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIH--- 510
S+ C C +G+ G C D+DEC+ +P C+ C N+ GSYQCSC G+ +
Sbjct: 2468 MGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDG 2526
Query: 511 ---------------------NMPGG-------------PKCYDRNECSEDKSLC-KNGV 585
N GG C D NEC LC G+
Sbjct: 2527 KTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPLLCGGKGI 2586
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC 765
C N GSF C+C G+ + +C D D N +C H C + G ++C
Sbjct: 2587 CQNTPGSFSCECQRGFSLDATGLNC------EDVDECDGN----HRCQHGCQNILGGYRC 2636
Query: 766 SCPYG 780
CP G
Sbjct: 2637 GCPQG 2641
Score = 106 bits (264), Expect = 1e-22
Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 1/173 (0%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT-NPTICDRGTCINSPGSYQCS 486
+C NG+CI + S+ C+C +G+ G C D DEC+ NP C GTC N GS++C+
Sbjct: 2180 ICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP--CGNGTCTNVIGSFECN 2237
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C +GF M C D NEC+++ LC C+N GS++C C GY +++ C
Sbjct: 2238 CNEGFEPGPMMN---CEDINECAQNPLLCALR-CMNTFGSYECTCPIGYALREDQKMCKD 2293
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQ 825
+ + ++ + D C C + GTF C CP GM D C ++
Sbjct: 2294 LDECAE--GLHD----CESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENE 2340
Score = 105 bits (261), Expect = 2e-22
Identities = 69/239 (28%), Positives = 96/239 (40%), Gaps = 27/239 (11%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK-- 318
C N + Y+C C +VL + G+ CK E + Q N N G F CK
Sbjct: 2505 CKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNT------LGGFTCKCP 2558
Query: 319 -------------------------NGRCIESGSSYECKCNLGFQESSDGKICSDIDECT 423
G C + S+ C+C GF + G C D+DEC
Sbjct: 2559 PGFTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD 2618
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
N C G C N G Y+C C G+ H +C D NECS + + C + C N G
Sbjct: 2619 GNHR-CQHG-CQNILGGYRCGCPQGYIQHYQ--WNQCVDENECS-NPNACGSASCYNTLG 2673
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
S+KC C SG+ C + + S +SK + C++ C+ G + C CP G
Sbjct: 2674 SYKCACPSGFSFDQFSSACHDVNECS-------SSK--NPCNYGCSNTEGGYLCGCPPG 2723
Score = 96.3 bits (238), Expect = 1e-19
Identities = 67/251 (26%), Positives = 97/251 (38%), Gaps = 25/251 (9%)
Frame = +1
Query: 103 CSFSYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLK 282
C+ + + +G C N+ + C C P G+ C E +
Sbjct: 2297 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPG---------- 2346
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE----CTTNPTICDRG 450
+C+NGRC+ SY C+CN GFQ SS G C D + TIC
Sbjct: 2347 ---------ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMA 2397
Query: 451 TCINSPGSYQCSCYDG-------FTIHNMPG----------GPKCY----DRNECSEDKS 567
+ + + C DG + +PG GP D +EC +
Sbjct: 2398 SSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPN 2457
Query: 568 LCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFV 747
LC NG CIN GSF+C C GY + CI + D+ S+ C++ C
Sbjct: 2458 LCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL---------DECSQSPKPCNYICKNT 2508
Query: 748 NGTFKCSCPYG 780
G+++CSCP G
Sbjct: 2509 EGSYQCSCPRG 2519
Score = 92.4 bits (228), Expect = 1e-18
Identities = 64/234 (27%), Positives = 93/234 (39%), Gaps = 16/234 (6%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKK----RTEYKPNQMNDAASSFNLK----- 282
C G C+N +Y C C PDF L+ G C K D + S N +
Sbjct: 1541 CVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGV 1600
Query: 283 ---SQCDKFGSFL---CKNGRCIESGSSYE-CKCNLGFQESSDGKICSDIDECTTNPTIC 441
S C G C+ + S Y C GF+ + I DIDEC P +C
Sbjct: 1601 SRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLC 1660
Query: 442 DRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
G CIN+ GS+QC C G+ + C D +EC +C G C N G++ C C
Sbjct: 1661 QGGNCINTFGSFQCECPQGYYLSE--DTRICEDIDECFAHPGVCGPGTCYNTLGNYTCIC 1718
Query: 622 NSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGM 783
Y+ + +C+ ++ S Y + + + C + F C C Y +
Sbjct: 1719 PPEYMQVNGGHNCMDMRKSFCYRSYNGTT-----CENELPFNVTKRMCCCTYNV 1767
Score = 90.9 bits (224), Expect = 4e-18
Identities = 56/169 (33%), Positives = 73/169 (43%), Gaps = 1/169 (0%)
Frame = +1
Query: 130 CKG-GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGS 306
C G G C N + CEC F LD G C+ E CD G+
Sbjct: 2581 CGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDE------------------CD--GN 2620
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
C++G C Y C C G+ + C D +EC +NP C +C N+ GSY+C+
Sbjct: 2621 HRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENEC-SNPNACGSASCYNTLGSYKCA 2678
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGY 633
C GF+ C+D NECS K+ C G C N G + C C GY
Sbjct: 2679 CPSGFSFDQFSSA--CHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2724
Score = 89.7 bits (221), Expect = 1e-17
Identities = 70/256 (27%), Positives = 109/256 (42%), Gaps = 30/256 (11%)
Frame = +1
Query: 103 CSFSYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLK 282
CS S++ + C+ GRC N ++C C + L G+ C E
Sbjct: 1976 CS-SFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE---------------- 2018
Query: 283 SQCDKF-GSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCI 459
C GS C G C S+ C C G++ S+ C DI+EC +P IC G+C
Sbjct: 2019 --CVALPGS--CSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPNICLFGSCT 2072
Query: 460 NSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLC----KNGVCINIHGSF-----K 612
N+PG +QC C GF + + G +C+D + S C +NG C ++ +F K
Sbjct: 2073 NTPGGFQCLCPPGFVLSD--NGRRCFDTRQ-----SFCFTNFENGKC-SVPKAFNTTKAK 2124
Query: 613 CQCN----SGY---VASSNKQDCISIQDSSDYS-----AVDDNSKYCSKC--------SH 732
C C+ G+ K D ++ QD Y ++ D + ++C +
Sbjct: 2125 CCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG 2184
Query: 733 YCAFVNGTFKCSCPYG 780
C +G+F+C CP G
Sbjct: 2185 QCINTDGSFRCECPMG 2200
Score = 89.0 bits (219), Expect = 2e-17
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 28/255 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G+C+N+ YRCEC F ++C Q D S N+
Sbjct: 1459 CENGQCLNVPGAYRCECEMGFTPASDSRSC---------QDIDECSFQNI---------- 1499
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C +G C + C C+ G++ G C+DIDEC +P C G C+N+PG Y+C+C
Sbjct: 1500 -CVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVNGLCVNTPGRYECNC 1557
Query: 490 YDGFTIHNMPGGPKCYDR--NEC------SEDKSL-CKNGVCINIHGSFKCQCNSGYVAS 642
F ++ P G C D C D SL C + + + S C C+ G
Sbjct: 1558 PPDFQLN--PTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRS-SCCCSLGKAWG 1614
Query: 643 SNKQDCISIQDSSDYSAVDDNSKY--------------CSKCSHYCAFVN-----GTFKC 765
+ + C + + Y+ + C + C N G+F+C
Sbjct: 1615 NPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQC 1674
Query: 766 SCPYGMESILDTGLC 810
CP G DT +C
Sbjct: 1675 ECPQGYYLSEDTRIC 1689
Score = 84.3 bits (207), Expect = 4e-16
Identities = 62/212 (29%), Positives = 86/212 (40%), Gaps = 13/212 (6%)
Frame = +1
Query: 100 FCSFSYYSEQCK-GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKP--NQMNDAASS 270
+C C+ GGRCI C C+ F G C++ P Q+N
Sbjct: 174 YCGQPVCENGCQNGGRCIAQP----CACVYGFT----GPQCERDYRTGPCFTQVN----- 220
Query: 271 FNLKSQCDKFGSFLCKNGRCIESGSSYECKCNL----------GFQESSDGKICSDIDEC 420
N Q G K C +G ++ C + GF + C D+DEC
Sbjct: 221 -NQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDEC 279
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIH 600
P IC G CIN+ GS++C C G KC D +ECS +C+ G C N
Sbjct: 280 QAIPGICQGGNCINTVGSFECRCPAGHKQSETT--QKCEDIDECSIIPGICETGECSNTV 337
Query: 601 GSFKCQCNSGYVASSNKQDCISIQDSSDYSAV 696
GS+ C C GYV S++ CI + +S +
Sbjct: 338 GSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGL 369
Score = 84.3 bits (207), Expect = 4e-16
Identities = 60/228 (26%), Positives = 95/228 (41%), Gaps = 25/228 (10%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE P + C ++PN + + +C + LC+ G CI + S+
Sbjct: 1617 CETCPPVNSTEYYTLCPGGEGFRPNPITIILEDID---ECQELPG-LCQGGNCINTFGSF 1672
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
+C+C G+ S D +IC DIDEC +P +C GTC N+ G+Y C C + N GG
Sbjct: 1673 QCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVN--GGHN 1730
Query: 532 CYDRNEC----SEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQ-DCISIQDSSDYSAV 696
C D + S + + C+N + N+ C C + NK + ++D+ +
Sbjct: 1731 CMDMRKSFCYRSYNGTTCENELPFNVTKRM-CCCTYNVGKAGNKPCEPCPTPGTADFKTI 1789
Query: 697 DDN---------------SKYCSKCSHYCA---FVN--GTFKCSCPYG 780
N C + CA +N G+F+C CP G
Sbjct: 1790 CGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTG 1837
Score = 81.6 bits (200), Expect = 3e-15
Identities = 68/279 (24%), Positives = 99/279 (35%), Gaps = 62/279 (22%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N++ YRC C + D G+ C E N++
Sbjct: 778 CANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRL------------------- 818
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTI--------------CDR 447
LC NG C + SY C C G+ ++ + C DI+EC +NP + C
Sbjct: 819 LCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSP 878
Query: 448 GTCINSPG-----SYQCSCY----DGFTIHNMPG-------------------------- 522
G+ ++S G S + +C+ D N+ G
Sbjct: 879 GSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDT 938
Query: 523 ----------GPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQ 672
G C D NEC +C NG C+N GSF C+C G + C+ I+
Sbjct: 939 ACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 998
Query: 673 DSSDYSAVDDNSKYCSKCSHYCAFVNGTFK---CSCPYG 780
Y D++ +C H V G F+ C C G
Sbjct: 999 MEQCYLKWDED-----ECIHP---VPGKFRMDACCCAVG 1029
Score = 80.9 bits (198), Expect = 4e-15
Identities = 78/299 (26%), Positives = 105/299 (35%), Gaps = 76/299 (25%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQAC---KKRTEYKPNQMNDAASSFN---LK 282
S C G C N + CEC P L G C K T + Q + + N LK
Sbjct: 857 SNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLK 916
Query: 283 SQC-----DKFGS---------------------------------FLCKNGRCIESGSS 348
S+C +GS +C NGRC+ S S
Sbjct: 917 SECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGS 976
Query: 349 YECKCNLGFQESSDGKICSDI-----------DECT--------TNPTICDRGTCINS-- 465
+ C+C G G++C DI DEC + C G +
Sbjct: 977 FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC 1036
Query: 466 -----PGS--YQCSCYDGFTIHN----MPGGPKCYDRNECSEDKSLCKNGVCINIHGSFK 612
PG+ Y+ C G N + G P D NEC +C G C N GSFK
Sbjct: 1037 EECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFK 1096
Query: 613 CQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMES 789
C+CNSG+ +++C I + + C S C G+F+C C G ES
Sbjct: 1097 CRCNSGFALDMEERNCTDIDECR------ISPDLCG--SGICVNTPGSFECECFEGYES 1147
Score = 79.0 bits (193), Expect = 2e-14
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 30/266 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG CIN ++CEC + L + + C+ E +
Sbjct: 1660 CQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPG------------------- 1700
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDEC----TTNPTICDRGTCINSPGSY 477
+C G C + +Y C C + + + G C D+ + + N T C+ N
Sbjct: 1701 VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRM 1760
Query: 478 QCSCYDGFTIHNMPGGP--------------------------KCYDRNECSEDKSLCKN 579
C Y+ N P P K D +EC E +C N
Sbjct: 1761 CCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICAN 1820
Query: 580 GVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTF 759
GVCIN GSF+C+C +G+ + D + + + D + DN C + + C G++
Sbjct: 1821 GVCINQIGSFRCECPTGF----SYNDLLLVCEDIDECSNGDN--LCQRNAD-CINSPGSY 1873
Query: 760 KCSCPYGMESILDTGLCAPNSQIVDV 837
+C C G + + G C ++ +++
Sbjct: 1874 RCECAAGFK-LSPNGACVDRNECLEI 1898
Score = 78.2 bits (191), Expect = 3e-14
Identities = 41/139 (29%), Positives = 64/139 (46%)
Frame = +1
Query: 409 IDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVC 588
ID C + +C G CI + SY+C C G+ C D +EC+ + C NG C
Sbjct: 494 IDICKHHANLCLNGRCIPTVSSYRCECNMGY---KQDANGDCIDVDECTSNP--CTNGDC 548
Query: 589 INIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCS 768
+N GS+ C+C++G+ + KQ CI I + + N + C +G+F+C
Sbjct: 549 VNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR--------CVNSDGSFQCI 600
Query: 769 CPYGMESILDTGLCAPNSQ 825
C G E D C + +
Sbjct: 601 CNAGFELTTDGKNCVDHDE 619
Score = 60.8 bits (146), Expect = 5e-09
Identities = 51/188 (27%), Positives = 78/188 (41%), Gaps = 22/188 (11%)
Frame = +1
Query: 313 CKNG-RCIESGSSYECKCNLGF------QESSDGKICSDIDE--CTTNPT--ICDRGTCI 459
C+NG RCI + C C GF ++ G + ++ C T +C + C
Sbjct: 184 CQNGGRCI----AQPCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC 239
Query: 460 NSPG---SYQCS--------CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGS 606
+ G + C C GF I N+ G C D +EC +C+ G CIN GS
Sbjct: 240 ATTGRAWGHPCEMCPAQPQPCRRGF-IPNIRTGA-CQDVDECQAIPGICQGGNCINTVGS 297
Query: 607 FKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
F+C+C +G+ S Q C I + S + + + C+ G++ C CP G
Sbjct: 298 FECRCPAGHKQSETTQKCEDIDECSIIPGICETGE--------CSNTVGSYFCVCPRGYV 349
Query: 787 SILDTGLC 810
+ D C
Sbjct: 350 TSTDGSRC 357
Score = 57.8 bits (138), Expect = 4e-08
Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 1/128 (0%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK-PNQMNDAASSFNLKSQCDK 297
+ +C+ G C N+ YRC C ++ Q C E PN
Sbjct: 2620 NHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA---------------- 2662
Query: 298 FGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSY 477
C + C + SY+C C GF C D++EC+++ C+ G C N+ G Y
Sbjct: 2663 -----CGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGY 2716
Query: 478 QCSCYDGF 501
C C G+
Sbjct: 2717 LCGCPPGY 2724
>sp|Q61555|FBN2_MOUSE Fibrillin-2 precursor
Length = 2907
Score = 141 bits (356), Expect = 2e-33
Identities = 75/232 (32%), Positives = 107/232 (46%)
Frame = +1
Query: 115 YYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCD 294
+++ C GRCI + YRC C + D G D
Sbjct: 493 HHANLCLNGRCIPTVSSYRCRCNMGYKQDANGDCI----------------------DVD 530
Query: 295 KFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGS 474
+ S C NG C+ + SY CKC+ GFQ + + C DIDEC N +C G C+NS GS
Sbjct: 531 ECTSNPCSNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGS 590
Query: 475 YQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQ 654
+QC C GF + G C D +EC+ ++C NG+CIN GSFKC C G++ + N +
Sbjct: 591 FQCICNAGFEL--TTDGKNCVDHDECT-TTNMCLNGMCINEDGSFKCVCKPGFILAPNGR 647
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
C + D + N +C G+F+C CP G+ +D +C
Sbjct: 648 YCTDV-DECQTPGICMNG--------HCINNEGSFRCDCPPGLAVGVDGRVC 690
Score = 140 bits (353), Expect = 5e-33
Identities = 78/226 (34%), Positives = 98/226 (43%)
Frame = +1
Query: 103 CSFSYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLK 282
CS S C+ G+C+NM Y+C C P + Q C D +
Sbjct: 1197 CSLS--DNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGC-----------TDIDECMIMN 1243
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCIN 462
CD +C S SYEC C+ G+ DG+ C+DIDEC NP ICD G C N
Sbjct: 1244 GGCDT---------QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTN 1294
Query: 463 SPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
PG Y+C CYDGF C D NEC + ++C G C N GSF C C GY
Sbjct: 1295 IPGEYRCLCYDGFMA--SMDMKTCIDVNECDLNPNICMFGECENTKGSFICHCQLGYSVK 1352
Query: 643 SNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
C +D + + C + C V G+FKCSC G
Sbjct: 1353 KGTTGC------TDVDECEIGAHNCDMHAS-CLNVPGSFKCSCREG 1391
Score = 138 bits (348), Expect = 2e-32
Identities = 74/229 (32%), Positives = 107/229 (46%), Gaps = 1/229 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C N ++C C F LD + + C E +
Sbjct: 1077 CTYGKCRNTIGSFKCRCNNGFALDMEERNCTDIDECR-------------------ISPD 1117
Query: 310 LCKNGRCIESGSSYECKCNLGFQES-SDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
LC +G C+ + S+EC+C G++ K C DIDEC NP +C GTC+N+ GS+QC
Sbjct: 1118 LCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCD 1177
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G + P C D NECS +LC+NG C+N+ G+++C CN GY A+ ++Q C
Sbjct: 1178 CPLGHELS--PSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTD 1235
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCA 813
I D+ C C G+++CSC G + D CA
Sbjct: 1236 I---------DECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCA 1275
Score = 131 bits (330), Expect = 2e-30
Identities = 60/176 (34%), Positives = 97/176 (55%)
Frame = +1
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCIN 462
++C F +C G+C + S++C+CN GF + + C+DIDEC +P +C G C+N
Sbjct: 1068 NECKAFPG-MCTYGKCRNTIGSFKCRCNNGFALDMEERNCTDIDECRISPDLCGSGICVN 1126
Query: 463 SPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
+PGS++C C++G+ M C D +EC + LC+ G C+N GSF+C C G+ S
Sbjct: 1127 TPGSFECECFEGYESGFMM-MKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELS 1185
Query: 643 SNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+++DC+ I + S + N K C + GT++CSC G ++ D C
Sbjct: 1186 PSREDCVDINECSLSDNLCRNGK--------CVNMIGTYQCSCNPGYQATPDRQGC 1233
Score = 131 bits (329), Expect = 3e-30
Identities = 71/214 (33%), Positives = 95/214 (44%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N Y C C P F L ND +C F
Sbjct: 1936 CANGTCKNTVGSYNCLCYPGFELTHN---------------NDCLDI----DECSSFFGQ 1976
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+C+NGRC S++C CN G++ + DGK C D +EC P C GTC N GS++C C
Sbjct: 1977 VCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCIC 2036
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
G+ + + C D NEC ED ++C G C N G F+C C G+V S N + C
Sbjct: 2037 PPGYEVRS----ENCIDINECDEDPNICLFGSCTNTPGGFQCICPPGFVLSDNGRRCFDT 2092
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
+ S ++ ++ KCS AF KC C
Sbjct: 2093 RQSFCFTNFEN-----GKCSVPKAFNTTKAKCCC 2121
Score = 122 bits (305), Expect = 2e-27
Identities = 57/160 (35%), Positives = 86/160 (53%), Gaps = 1/160 (0%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGT-CINSPGSYQCS 486
+C NG CI S+ C+C GF + +C DIDEC+ +C R CINSPGSY+C
Sbjct: 1811 ICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE 1870
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C GF + P G C DRNEC E ++C +G+C+++ GS++C CN+G+ AS ++ C+
Sbjct: 1871 CAAGFKLS--PNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICNNGFKASQDQTMCMD 1927
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
+ + + + C G++ C C G E
Sbjct: 1928 VDECERHPCANGT----------CKNTVGSYNCLCYPGFE 1957
Score = 116 bits (290), Expect = 9e-26
Identities = 82/305 (26%), Positives = 111/305 (36%), Gaps = 88/305 (28%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFNL--KS 285
C+ GRC+N+ YRCEC F G C E A+SS NL KS
Sbjct: 2342 CENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTMCQMASSSRNLVTKS 2401
Query: 286 QCDKFGS------------------------------------------FLCKNGRCIES 339
+C G LC NG+C+ +
Sbjct: 2402 ECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYATDGRDIDECKVMPSLCTNGQCVNT 2461
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIH--- 510
S+ C C +G+ G C D+DEC+ +P C+ C N+ GSYQCSC G+ +
Sbjct: 2462 MGSFRCFCKVGYTMDISGTACVDLDECSQSPKPCN-FICKNTKGSYQCSCPRGYVLQEDG 2520
Query: 511 ---------------------NMPGG-------------PKCYDRNECSEDKSLC-KNGV 585
N GG C D NEC SLC G+
Sbjct: 2521 KTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGI 2580
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC 765
C N GSF C+C G+ ++ +C D D N +C H C + G ++C
Sbjct: 2581 CQNTPGSFSCECQRGFSLDASGLNC------EDVDECDGN----HRCQHGCQNILGGYRC 2630
Query: 766 SCPYG 780
CP+G
Sbjct: 2631 GCPHG 2635
Score = 115 bits (288), Expect = 2e-25
Identities = 80/262 (30%), Positives = 108/262 (41%), Gaps = 43/262 (16%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN +RCEC F + C+ E C +
Sbjct: 1812 CANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDE------------------CSNGDNL 1853
Query: 310 LCKNGRCIESGSSYECKC-----------------------------------------N 366
+N CI S SY C+C N
Sbjct: 1854 CQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICN 1913
Query: 367 LGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTI-HNMPGGPKCYDR 543
GF+ S D +C D+DEC +P C GTC N+ GSY C CY GF + HN C D
Sbjct: 1914 NGFKASQDQTMCMDVDECERHP--CANGTCKNTVGSYNCLCYPGFELTHN----NDCLDI 1967
Query: 544 NECSE-DKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCS 720
+ECS +C+NG C N GSFKC CN GY + + ++CI D+++ A+ + CS
Sbjct: 1968 DECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCI---DTNECVALPGS---CS 2021
Query: 721 KCSHYCAFVNGTFKCSCPYGME 786
+ C + G+F+C CP G E
Sbjct: 2022 PGT--CQNLEGSFRCICPPGYE 2041
Score = 114 bits (284), Expect = 5e-25
Identities = 74/269 (27%), Positives = 103/269 (38%), Gaps = 55/269 (20%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQAC----KKRTEY-------------------- 237
C G CIN + +RC+C P + G+ C + T Y
Sbjct: 661 CMNGHCINNEGSFRCDCPPGLAVGVDGRVCVDTHMRSTCYGEIKKGVCVRPFPGAVTKSE 720
Query: 238 -----------KPNQMNDAASSFNLKSQCDK---------------FGSFLCKNGRCIES 339
+P Q A +S C +C NG C
Sbjct: 721 CCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICANGICENL 780
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
+Y C CN G++ + G+ C DIDEC N +CD G C N+PGSY C+C G+ +
Sbjct: 781 RGTYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVLPTET 840
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVD 699
C D NEC + + C NG C N GSF C+C+ G SS CI + + +
Sbjct: 841 --ETCEDVNEC--ESNPCVNGACRNNLGSFHCECSPGSKLSSTGLICIDSLKGTCWLNIQ 896
Query: 700 DNS-----KYCSKCSHYCAFVNGTFKCSC 771
DN + S CA + G + C
Sbjct: 897 DNRCEVNINGATLKSECCATLGGAWGSPC 925
Score = 113 bits (282), Expect = 8e-25
Identities = 64/201 (31%), Positives = 90/201 (44%), Gaps = 23/201 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNL---------- 279
C G+CIN +RCEC + LD G C E + N+
Sbjct: 2175 CSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGCFECTCNE 2234
Query: 280 ------KSQCDKFGS-----FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT 426
C+ LC RC+ + SYEC C +G+ D K+C D+DEC
Sbjct: 2235 GFEPGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPVGYGLREDQKMCKDLDECAE 2293
Query: 427 NPTICD-RGT-CINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIH 600
C+ RG C N G++ C C G P G C D NEC +C+NG C+NI
Sbjct: 2294 GLHDCESRGMMCKNLIGTFMCICPPGMA--RRPDGEGCVDENECRTKPGICENGRCVNII 2351
Query: 601 GSFKCQCNSGYVASSNKQDCI 663
GS++C+CN G+ +SS+ +C+
Sbjct: 2352 GSYRCECNEGFQSSSSGTECL 2372
Score = 111 bits (278), Expect = 2e-24
Identities = 69/238 (28%), Positives = 102/238 (42%), Gaps = 23/238 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKK--RTEYKPNQMNDAASSFNL----KSQC 291
C G C N K + C C + + K C E + + AS N+ K C
Sbjct: 1329 CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNVPGSFKCSC 1388
Query: 292 DKF----------------GSFLCK-NGRCIESGSSYECKCNLGFQESSDGKICSDIDEC 420
+ G+ C N +C+ + SY C C+ GF + DG CSD+DEC
Sbjct: 1389 REGWVGNGIKCIDLDECANGTHQCSINAQCVNTPGSYRCACSEGF--TGDGFTCSDVDEC 1446
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIH 600
N +C+ G C+N PG+Y+C C GFT C D +ECS +++C G C N+
Sbjct: 1447 AENTNLCENGQCLNVPGAYRCECEMGFT--PASDSRSCQDIDECS-FQNICVFGTCNNLP 1503
Query: 601 GSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCP 774
G F C C+ GY +C I + +D + + C G ++C+CP
Sbjct: 1504 GMFHCICDDGYELDRTGGNCTDIDECAD---------PINCVNGLCVNTPGRYECNCP 1552
Score = 108 bits (269), Expect = 3e-23
Identities = 70/233 (30%), Positives = 96/233 (41%), Gaps = 21/233 (9%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMN------DAASSFNLK-------- 282
C N K Y+C C +VL + G+ CK E + Q N + F K
Sbjct: 2499 CKNTKGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH 2558
Query: 283 -------SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTIC 441
++C S G C + S+ C+C GF + G C D+DEC N C
Sbjct: 2559 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDASGLNCEDVDECDGNHR-C 2617
Query: 442 DRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
G C N G Y+C C G H +C D NECS + C + C N GS+KC C
Sbjct: 2618 QHG-CQNILGGYRCGCPHGDVQHYQ--WNQCVDENECS-NPGACGSASCYNTLGSYKCAC 2673
Query: 622 NSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
SG+ C + + S +SK + CS+ C+ G + C CP G
Sbjct: 2674 PSGFSFDQFSSACHDVNECS-------SSK--NPCSYGCSNTEGGYLCGCPPG 2717
Score = 105 bits (262), Expect = 2e-22
Identities = 70/255 (27%), Positives = 103/255 (40%), Gaps = 25/255 (9%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF 300
+ C G CIN ++C C P F+L G+ C E C
Sbjct: 617 TNMCLNGMCINEDGSFKCVCKPGFILAPNGRYCTDVDE------------------CQTP 658
Query: 301 GSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINS-PGSY 477
G +C NG CI + S+ C C G DG++C D +T +G C+ PG+
Sbjct: 659 G--ICMNGHCINNEGSFRCDCPPGLAVGVDGRVCVDTHMRSTCYGEIKKGVCVRPFPGAV 716
Query: 478 ---QCSCYD---GFTIHNMPGGPK--------CY----------DRNECSEDKSLCKNGV 585
+C C + GF P K C D NEC+ D +C NG+
Sbjct: 717 TKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGIGITVDGRDINECALDPDICANGI 776
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC 765
C N+ G+++C CNSGY ++ ++CI I + + DN C G++ C
Sbjct: 777 CENLRGTYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNG--------LCRNTPGSYSC 828
Query: 766 SCPYGMESILDTGLC 810
+CP G +T C
Sbjct: 829 TCPPGYVLPTETETC 843
Score = 103 bits (256), Expect = 8e-22
Identities = 57/173 (32%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT-NPTICDRGTCINSPGSYQCS 486
+C NG+CI + S+ C+C +G+ G C D DEC+ NP C GTC N G ++C+
Sbjct: 2174 ICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP--CGNGTCTNVIGCFECT 2231
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C +GF M C D NEC+++ LC C+N GS++C C GY +++ C
Sbjct: 2232 CNEGFEPGPMMN---CEDINECAQNPLLCAFR-CMNTFGSYECTCPVGYGLREDQKMCKD 2287
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQ 825
+ + ++ + D C C + GTF C CP GM D C ++
Sbjct: 2288 LDECAE--GLHD----CESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENE 2334
Score = 93.2 bits (230), Expect = 9e-19
Identities = 62/251 (24%), Positives = 92/251 (36%), Gaps = 25/251 (9%)
Frame = +1
Query: 103 CSFSYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLK 282
C+ + + +G C N+ + C C P G+ C E +
Sbjct: 2291 CAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPG---------- 2340
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSD--------------IDEC 420
+C+NGRC+ SY C+CN GFQ SS G C D
Sbjct: 2341 ---------ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTMCQMA 2391
Query: 421 TTNPTICDRGTCINSPG---SYQCSC--------YDGFTIHNMPGGPKCYDRNECSEDKS 567
+++ + + C G +QC Y H D +EC S
Sbjct: 2392 SSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYATDGRDIDECKVMPS 2451
Query: 568 LCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFV 747
LC NG C+N GSF+C C GY + C+ + D+ S+ C+ C
Sbjct: 2452 LCTNGQCVNTMGSFRCFCKVGYTMDISGTACVDL---------DECSQSPKPCNFICKNT 2502
Query: 748 NGTFKCSCPYG 780
G+++CSCP G
Sbjct: 2503 KGSYQCSCPRG 2513
Score = 92.8 bits (229), Expect = 1e-18
Identities = 62/234 (26%), Positives = 93/234 (39%), Gaps = 16/234 (6%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQAC------------KKRTEYKPNQMNDAASSF 273
C G C+N +Y C C PDF L+ G C R + + +A
Sbjct: 1535 CVNGLCVNTPGRYECNCPPDFQLNATGVGCVDNRVGNCYLKFGPRGDGSLSCNTEAGVGV 1594
Query: 274 NLKSQCDKFGSFL---CKNGRCIESGSSYE-CKCNLGFQESSDGKICSDIDECTTNPTIC 441
+ S C G C+ + S Y C GF+ + I DIDEC P +C
Sbjct: 1595 SRSSCCCSLGKAWGNPCETCPPVNSTEHYTLCPGGEGFRPNPITIILEDIDECQELPGLC 1654
Query: 442 DRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
G CIN+ GS+QC C G+ + C D +EC +C G C N G++ C C
Sbjct: 1655 QGGNCINTFGSFQCECPQGYYLSEET--RICEDIDECFAHPGVCGPGTCYNTLGNYTCIC 1712
Query: 622 NSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGM 783
Y+ + +C+ ++ S Y + + + C + F C C Y +
Sbjct: 1713 PPEYMQVNGGHNCMDMRKSFCYRSYNGTT-----CENELPFNVTKRMCCCTYNV 1761
Score = 89.4 bits (220), Expect = 1e-17
Identities = 70/256 (27%), Positives = 109/256 (42%), Gaps = 30/256 (11%)
Frame = +1
Query: 103 CSFSYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLK 282
CS S++ + C+ GRC N ++C C + L G+ C E
Sbjct: 1970 CS-SFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNE---------------- 2012
Query: 283 SQCDKF-GSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCI 459
C GS C G C S+ C C G++ S+ C DI+EC +P IC G+C
Sbjct: 2013 --CVALPGS--CSPGTCQNLEGSFRCICPPGYEVRSEN--CIDINECDEDPNICLFGSCT 2066
Query: 460 NSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLC----KNGVCINIHGSF-----K 612
N+PG +QC C GF + + G +C+D + S C +NG C ++ +F K
Sbjct: 2067 NTPGGFQCICPPGFVLSD--NGRRCFDTRQ-----SFCFTNFENGKC-SVPKAFNTTKAK 2118
Query: 613 CQCN----SGY---VASSNKQDCISIQDSSDYS-----AVDDNSKYCSKC--------SH 732
C C+ G+ K D ++ QD Y ++ D + ++C +
Sbjct: 2119 CCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNG 2178
Query: 733 YCAFVNGTFKCSCPYG 780
C +G+F+C CP G
Sbjct: 2179 QCINTDGSFRCECPMG 2194
Score = 89.4 bits (220), Expect = 1e-17
Identities = 65/215 (30%), Positives = 87/215 (40%), Gaps = 7/215 (3%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C N + CEC F LD G C+ E CD G+ C+
Sbjct: 2579 GICQNTPGSFSCECQRGFSLDASGLNCEDVDE------------------CD--GNHRCQ 2618
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C Y C C G + C D +EC +NP C +C N+ GSY+C+C G
Sbjct: 2619 HG-CQNILGGYRCGCPHGDVQHYQWNQCVDENEC-SNPGACGSASCYNTLGSYKCACPSG 2676
Query: 499 FTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQD- 675
F+ C+D NECS K+ C G C N G + C C GY + C+S
Sbjct: 2677 FSFDQFSSA--CHDVNECSSSKNPCSYG-CSNTEGGYLCGCPPGYF-RVGQGHCVSGMGF 2732
Query: 676 ------SSDYSAVDDNSKYCSKCSHYCAFVNGTFK 762
S D A DD + + + C +NG K
Sbjct: 2733 NKGQYLSVDAEAEDDENALSPEACYECK-INGYTK 2766
Score = 85.5 bits (210), Expect = 2e-16
Identities = 79/299 (26%), Positives = 106/299 (35%), Gaps = 76/299 (25%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQAC---KKRTEYKPNQMNDAASSFN---LK 282
S C G C N + CEC P L G C K T + Q N + N LK
Sbjct: 851 SNPCVNGACRNNLGSFHCECSPGSKLSSTGLICIDSLKGTCWLNIQDNRCEVNINGATLK 910
Query: 283 SQC-----DKFGS---------------------------------FLCKNGRCIESGSS 348
S+C +GS +C NGRC+ S S
Sbjct: 911 SECCATLGGAWGSPCERCELDAACPRGFARIKGVTCEDVNECEVFPGVCPNGRCVNSKGS 970
Query: 349 YECKCNLGFQESSDGKICSDI-----------DECT--------TNPTICDRGTCINS-- 465
+ C+C G G++C DI DEC + C G +
Sbjct: 971 FHCECPEGLTLDGTGRVCLDIRMEHCFLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC 1030
Query: 466 -----PGS--YQCSCYDGFTIHN----MPGGPKCYDRNECSEDKSLCKNGVCINIHGSFK 612
PG+ Y+ C G N + G P C D NEC +C G C N GSFK
Sbjct: 1031 EECPKPGTKEYETLCPRGPGFANRGDILTGRPFCKDINECKAFPGMCTYGKCRNTIGSFK 1090
Query: 613 CQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMES 789
C+CN+G+ +++C I + + C S C G+F+C C G ES
Sbjct: 1091 CRCNNGFALDMEERNCTDIDECR------ISPDLCG--SGICVNTPGSFECECFEGYES 1141
Score = 84.7 bits (208), Expect = 3e-16
Identities = 63/253 (24%), Positives = 97/253 (38%), Gaps = 26/253 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G+C+N+ YRCEC F ++C Q D S N+
Sbjct: 1453 CENGQCLNVPGAYRCECEMGFTPASDSRSC---------QDIDECSFQNI---------- 1493
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C G C + C C+ G++ G C+DIDEC +P C G C+N+PG Y+C+C
Sbjct: 1494 -CVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVNGLCVNTPGRYECNC 1551
Query: 490 YDGFTIHNMPGG------PKCYDRNECSEDKSL-CKNGVCINIHGSFKCQCNSGYVASSN 648
F ++ G CY + D SL C + + S C C+ G +
Sbjct: 1552 PPDFQLNATGVGCVDNRVGNCYLKFGPRGDGSLSCNTEAGVGVSRS-SCCCSLGKAWGNP 1610
Query: 649 KQDCISIQDSSDYSAVDDNSKY--------------CSKCSHYCAFVN-----GTFKCSC 771
+ C + + Y+ + C + C N G+F+C C
Sbjct: 1611 CETCPPVNSTEHYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCEC 1670
Query: 772 PYGMESILDTGLC 810
P G +T +C
Sbjct: 1671 PQGYYLSEETRIC 1683
Score = 83.6 bits (205), Expect = 7e-16
Identities = 61/208 (29%), Positives = 87/208 (41%), Gaps = 9/208 (4%)
Frame = +1
Query: 100 FCSFSYYSEQCK-GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKP--NQMNDAASS 270
+C C+ GGRCI RC C+ F G C++ P Q+N+
Sbjct: 174 YCGQPVCENGCQNGGRCIGPN---RCACVYGFT----GPQCERDYRTGPCFTQVNNQMCQ 226
Query: 271 FNLKS-QCDKFGSFLCKN-----GRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNP 432
L C K + C G E + C GF + C D+DEC P
Sbjct: 227 GQLTGIVCTK--TLCCATIGRAWGHPCEMCPAQPQPCRPGFIPNIRTGACQDVDECQAIP 284
Query: 433 TICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFK 612
+C G CIN+ GS++C C G KC D +ECS +C+ G C N GS+
Sbjct: 285 GLCQGGNCINTVGSFECRCPAGHKQSETT--QKCEDIDECSVIPGVCETGDCSNTVGSYF 342
Query: 613 CQCNSGYVASSNKQDCISIQDSSDYSAV 696
C C G+V S++ CI + + +S +
Sbjct: 343 CLCPRGFVTSTDGSRCIDQRAGTCFSGL 370
Score = 83.2 bits (204), Expect = 9e-16
Identities = 59/228 (25%), Positives = 95/228 (41%), Gaps = 25/228 (10%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE P + C ++PN + + +C + LC+ G CI + S+
Sbjct: 1611 CETCPPVNSTEHYTLCPGGEGFRPNPITIILEDID---ECQELPG-LCQGGNCINTFGSF 1666
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
+C+C G+ S + +IC DIDEC +P +C GTC N+ G+Y C C + N GG
Sbjct: 1667 QCECPQGYYLSEETRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVN--GGHN 1724
Query: 532 CYDRNEC----SEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQ-DCISIQDSSDYSAV 696
C D + S + + C+N + N+ C C + NK + ++D+ +
Sbjct: 1725 CMDMRKSFCYRSYNGTTCENELPFNVTKRM-CCCTYNVGKAGNKPCEPCPTPGTADFKTI 1783
Query: 697 DDN---------------SKYCSKCSHYCA---FVN--GTFKCSCPYG 780
N C + CA +N G+F+C CP G
Sbjct: 1784 CGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTG 1831
Score = 81.6 bits (200), Expect = 3e-15
Identities = 70/281 (24%), Positives = 96/281 (34%), Gaps = 64/281 (22%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N++ YRC C + D G+ C E N++
Sbjct: 772 CANGICENLRGTYRCNCNSGYEPDASGRNCIDIDECLVNRL------------------- 812
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCIN--------- 462
LC NG C + SY C C G+ ++ + C D++EC +NP C G C N
Sbjct: 813 LCDNGLCRNTPGSYSCTCPPGYVLPTETETCEDVNECESNP--CVNGACRNNLGSFHCEC 870
Query: 463 SPGSYQCS----CYDGF----------------------------TIHNMPGGP------ 528
SPGS S C D T+ G P
Sbjct: 871 SPGSKLSSTGLICIDSLKGTCWLNIQDNRCEVNINGATLKSECCATLGGAWGSPCERCEL 930
Query: 529 --------------KCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C D NEC +C NG C+N GSF C+C G + C+
Sbjct: 931 DAACPRGFARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD 990
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFK---CSCPYG 780
I+ + D++ +C H V G F+ C C G
Sbjct: 991 IRMEHCFLKWDED-----ECIHP---VPGKFRMDACCCAVG 1023
Score = 79.7 bits (195), Expect = 1e-14
Identities = 60/266 (22%), Positives = 103/266 (38%), Gaps = 30/266 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG CIN ++CEC + L ++ + C+ E +
Sbjct: 1654 CQGGNCINTFGSFQCECPQGYYLSEETRICEDIDECFAHPG------------------- 1694
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDEC----TTNPTICDRGTCINSPGSY 477
+C G C + +Y C C + + + G C D+ + + N T C+ N
Sbjct: 1695 VCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRM 1754
Query: 478 QCSCYDGFTIHNMPGGP--------------------------KCYDRNECSEDKSLCKN 579
C Y+ N P P K D +EC E +C N
Sbjct: 1755 CCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICAN 1814
Query: 580 GVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTF 759
GVCIN GSF+C+C +G+ + D + + + D + DN C + + C G++
Sbjct: 1815 GVCINQIGSFRCECPTGF----SYNDLLLVCEDIDECSNGDN--LCQRNAD-CINSPGSY 1867
Query: 760 KCSCPYGMESILDTGLCAPNSQIVDV 837
+C C G + + G C ++ +++
Sbjct: 1868 RCECAAGFK-LSPNGACVDRNECLEI 1892
Score = 78.2 bits (191), Expect = 3e-14
Identities = 41/139 (29%), Positives = 64/139 (46%)
Frame = +1
Query: 409 IDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVC 588
ID C + +C G CI + SY+C C G+ C D +EC+ + C NG C
Sbjct: 488 IDICKHHANLCLNGRCIPTVSSYRCRCNMGY---KQDANGDCIDVDECTSNP--CSNGDC 542
Query: 589 INIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCS 768
+N GS+ C+C++G+ + KQ CI I + + N + C +G+F+C
Sbjct: 543 VNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR--------CVNSDGSFQCI 594
Query: 769 CPYGMESILDTGLCAPNSQ 825
C G E D C + +
Sbjct: 595 CNAGFELTTDGKNCVDHDE 613
Score = 60.8 bits (146), Expect = 5e-09
Identities = 53/188 (28%), Positives = 76/188 (40%), Gaps = 22/188 (11%)
Frame = +1
Query: 313 CKNG-RCIESGSSYECKCNLGF------QESSDGKICSDIDE--CTTNPT--ICDRGTCI 459
C+NG RCI C C GF ++ G + ++ C T +C + C
Sbjct: 184 CQNGGRCIGPN---RCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC 240
Query: 460 NSPG---SYQCS--------CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGS 606
+ G + C C GF I N+ G C D +EC LC+ G CIN GS
Sbjct: 241 ATIGRAWGHPCEMCPAQPQPCRPGF-IPNIRTGA-CQDVDECQAIPGLCQGGNCINTVGS 298
Query: 607 FKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
F+C+C +G+ S Q C I + S V + C+ G++ C CP G
Sbjct: 299 FECRCPAGHKQSETTQKCEDIDECSVIPGVCETGD--------CSNTVGSYFCLCPRGFV 350
Query: 787 SILDTGLC 810
+ D C
Sbjct: 351 TSTDGSRC 358
Score = 32.0 bits (71), Expect = 2.4
Identities = 24/92 (26%), Positives = 34/92 (36%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C C N Y+C C F D+ AC + +N+ +SS K+ C S+
Sbjct: 2657 CGSASCYNTLGSYKCACPSGFSFDQFSSAC--------HDVNECSSS---KNPC----SY 2701
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICS 405
C N + Y C C G+ G S
Sbjct: 2702 GCSN-----TEGGYLCGCPPGYFRVGQGHCVS 2728
>sp|P35555|FBN1_HUMAN Fibrillin-1 precursor
Length = 2871
Score = 139 bits (350), Expect = 1e-32
Identities = 84/239 (35%), Positives = 102/239 (42%), Gaps = 22/239 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK------PN------------QMN 255
C+GG C N + YRCEC P L AC E + PN N
Sbjct: 1124 CRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACN 1183
Query: 256 DAASSFNLKSQCDKFGSFLCKNGRC----IESGSSYECKCNLGFQESSDGKICSDIDECT 423
S + C NG C S SYEC C GF D + C+DIDEC
Sbjct: 1184 PGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECE 1243
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
NP ICD G C N PG Y+C CYDGF C D NEC + ++C +G C N G
Sbjct: 1244 DNPNICDGGQCTNIPGEYRCLCYDGFMASE--DMKTCVDVNECDLNPNICLSGTCENTKG 1301
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
SF C C+ GY K C +D + + + C K + C G+FKCSC G
Sbjct: 1302 SFICHCDMGYSGKKGKTGC------TDINECEIGAHNCGKHA-VCTNTAGSFKCSCSPG 1353
Score = 136 bits (343), Expect = 7e-32
Identities = 77/227 (33%), Positives = 108/227 (47%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ GRCI YRCEC F LD +G+ +C+K
Sbjct: 460 CQNGRCIPTPGSYRCECNKGFQLDLRGECIDV-------------------DECEKNP-- 498
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C G CI + SY C+C G+Q + C DIDEC N IC+ G CIN+ GS+ C C
Sbjct: 499 -CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVC 557
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
GF H G C D +ECS +++C NG+CIN GSFKC C G+ +S+ + C I
Sbjct: 558 NAGF--HVTRDGKNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDI 614
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + + N + C +G+++C C G+ LD +C
Sbjct: 615 NE-CETPGICMNGR--------CVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 133 bits (335), Expect = 6e-31
Identities = 76/242 (31%), Positives = 122/242 (50%), Gaps = 25/242 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLD------------KQGQACKK-----------RTEYK 240
C+ G CINM +RCEC F + + G C++ R + K
Sbjct: 1777 CENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCK 1836
Query: 241 PNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDEC 420
P + N +++C + + +C +G+CI++ S+ C C+ GF+ + D +C DI+EC
Sbjct: 1837 PGYRFTSTGQCNDRNECQEIPN-ICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC 1895
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTI-HNMPGGPKCYDRNEC-SEDKSLCKNGVCIN 594
+ C GTC N+ GS+ C C GF + HN C D +EC S + +LC+NG CIN
Sbjct: 1896 ERDA--CGNGTCRNTIGSFNCRCNHGFILSHNND----CIDVDECASGNGNLCRNGQCIN 1949
Query: 595 IHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCP 774
GSF+CQCN GY + + + C+ I + + C+ + C ++G+++C CP
Sbjct: 1950 TVGSFQCQCNEGYEVAPDGRTCVDINECLL------EPRKCAPGT--CQNLDGSYRCICP 2001
Query: 775 YG 780
G
Sbjct: 2002 PG 2003
Score = 131 bits (330), Expect = 2e-30
Identities = 73/242 (30%), Positives = 105/242 (43%), Gaps = 7/242 (2%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C N ++C C F LD + + C E +
Sbjct: 1039 CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECR-------------------ISPD 1079
Query: 310 LCKNGRCIESGSSYECKCNLGFQES-SDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
LC G+C+ + +ECKC+ G++ K C DIDEC +P +C G C N+ GSY+C
Sbjct: 1080 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCE 1139
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G + P C D NEC LC NG C+N+ G ++C CN GY ++ ++ C+
Sbjct: 1140 CPPGHQLS--PNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVD 1197
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG------MESILDTGLCAPNSQI 828
I D+ S C +C G+++CSC G S D C N I
Sbjct: 1198 I---------DECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI 1248
Query: 829 VD 834
D
Sbjct: 1249 CD 1250
Score = 129 bits (324), Expect = 1e-29
Identities = 69/216 (31%), Positives = 101/216 (46%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
+ C G C N + C C F+L ND +C
Sbjct: 1898 DACGNGTCRNTIGSFNCRCNHGFILSHN---------------NDCIDV----DECASGN 1938
Query: 304 SFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQC 483
LC+NG+CI + S++C+CN G++ + DG+ C DI+EC P C GTC N GSY+C
Sbjct: 1939 GNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRC 1998
Query: 484 SCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCI 663
C G+++ N KC D +EC E+ +C G C N GSFKC C G+ SS+ + C
Sbjct: 1999 ICPPGYSLQN----EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQ 2054
Query: 664 SIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
++ S Y+ + KCS + + +C C
Sbjct: 2055 DLRMSYCYAKFEG-----GKCSSPKSRNHSKQECCC 2085
Score = 129 bits (323), Expect = 1e-29
Identities = 65/213 (30%), Positives = 106/213 (49%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE P + + C + + ++ + F ++C S LC +G+C + S+
Sbjct: 993 CEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPS-LCTHGKCRNTIGSF 1051
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
+C+C+ GF S+ + C+DIDEC +P +C RG C+N+PG ++C C +G+ M
Sbjct: 1052 KCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMM-MKN 1110
Query: 532 CYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSK 711
C D +EC D LC+ GVC N GS++C+C G+ S N CI I + + + N +
Sbjct: 1111 CMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGR 1170
Query: 712 YCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
C + G ++C+C G S D C
Sbjct: 1171 --------CVNLIGKYQCACNPGYHSTPDRLFC 1195
Score = 120 bits (302), Expect = 4e-27
Identities = 77/279 (27%), Positives = 120/279 (43%), Gaps = 36/279 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF-GS 306
C GG+C N+ +YRC C F+ + + C E D + L C+ GS
Sbjct: 1249 CDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNEC------DLNPNICLSGTCENTKGS 1302
Query: 307 FLC-----------------------------KNGRCIESGSSYECKCNLGFQESSDGKI 399
F+C K+ C + S++C C+ G+ DG
Sbjct: 1303 FICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGW--IGDGIK 1360
Query: 400 CSDIDECTTNPTICDR-GTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCK 576
C+D+DEC+ +C + C N+ GSY+C C +G+T G C D +ECSE+ +LC
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT----GDGFTCTDLDECSENLNLCG 1416
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF---- 744
NG C+N G ++C+C+ G+V S++ + C I + S + C F
Sbjct: 1417 NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECS--------------LPNICVFGTCH 1462
Query: 745 -VNGTFKCSCPYGMESILDTGLCAPNSQIVDVQFDIPNN 858
+ G F+C C G E G C ++ +D I N
Sbjct: 1463 NLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGN 1501
Score = 120 bits (301), Expect = 5e-27
Identities = 62/168 (36%), Positives = 89/168 (52%)
Frame = +1
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+LC+NGRCI + SY C+CN GFQ G+ C D+DEC NP C G CIN+ GSY C
Sbjct: 458 YLCQNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGECINNQGSYTCQ 514
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G+ + +C D +EC ++ +C NG CIN GSF C CN+G+ + + ++C
Sbjct: 515 CRAGY--QSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCED 572
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + S + + C +G+FKC C G + D C
Sbjct: 573 MDECSIRNMC---------LNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 118 bits (295), Expect = 2e-26
Identities = 76/241 (31%), Positives = 99/241 (41%), Gaps = 50/241 (20%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACK------------KR--------------- 228
C GRC+N YRCEC P + G+ C KR
Sbjct: 623 CMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSE 682
Query: 229 -----TEY---KPNQMNDAASSFNLKSQCDKFGSF---------------LCKNGRCIES 339
TEY +P Q A +S ++ C +C NG C
Sbjct: 683 CCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENL 742
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
+Y+C CN G++ S GK C DI+EC N +CD G C N+PGS+ C+C GF P
Sbjct: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY--KP 800
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVD 699
C D +EC + S C NGVC N GSF C+C+S K CI + + V
Sbjct: 801 DLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI 858
Query: 700 D 702
D
Sbjct: 859 D 859
Score = 114 bits (286), Expect = 3e-25
Identities = 76/294 (25%), Positives = 112/294 (38%), Gaps = 58/294 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKK-------RTEYKPNQMNDAASSFNL-KS 285
C G C N Y C C PD++ G C R Y NQ D FN+ K
Sbjct: 1658 CGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKK 1717
Query: 286 QC----------------------DKFGSF----------------------------LC 315
C D+F + +C
Sbjct: 1718 MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC 1777
Query: 316 KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYD 495
+NG CI S+ C+C +GF + +C DIDEC P CIN+ GSY+C C
Sbjct: 1778 ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP 1837
Query: 496 GFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQD 675
G+ +C DRNEC E ++C +G CI+ GSF C C++G+ + ++ C+ I +
Sbjct: 1838 GY---RFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINE 1894
Query: 676 SSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
+ + C G+F C C +G + + N+ +DV
Sbjct: 1895 CERDACGNGT----------CRNTIGSFNCRCNHGF-------ILSHNNDCIDV 1931
Score = 114 bits (286), Expect = 3e-25
Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 34/261 (13%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G C+N + Y C C +T Y P+ + N +Q K +F
Sbjct: 2413 CRNGECVNDRGSYHCIC---------------KTGYTPDITGTSCVDLNECNQAPKPCNF 2457
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+CKN + SY+C C G+ DG+ C D+DEC T C + C+N+ G + C C
Sbjct: 2458 ICKN-----TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKC 2511
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLC-KNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
GFT H+ C D NEC+ D +LC G+C N GSF C+C G+ C
Sbjct: 2512 PPGFTQHHT----SCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCED 2567
Query: 667 IQDSSDY-----------------------------SAVDDN----SKYCSKCSHYCAFV 747
+ + VD+N + C S C
Sbjct: 2568 VDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGAS--CHNT 2625
Query: 748 NGTFKCSCPYGMESILDTGLC 810
G++KC CP G + +G C
Sbjct: 2626 LGSYKCMCPAGFQYEQFSGGC 2646
Score = 113 bits (282), Expect = 8e-25
Identities = 66/215 (30%), Positives = 97/215 (45%), Gaps = 3/215 (1%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNG 324
C N YRC C + D G C +++ + + NL C NG
Sbjct: 1380 CKNTMGSYRCLCKEGYTGD--GFTC--------TDLDECSENLNL-----------CGNG 1418
Query: 325 RCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFT 504
+C+ + Y C+C++GF S+DGK C DIDEC+ P IC GTC N PG ++C C G+
Sbjct: 1419 QCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYE 1477
Query: 505 IHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSD 684
+ G C D NEC D + C +G C+N GS+ C C + + + C+ + +
Sbjct: 1478 LDR--SGGNCTDVNECL-DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNC 1534
Query: 685 YSAV---DDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
Y + DN + CS+ C C G
Sbjct: 1535 YLDIRPRGDNGD--TACSNEIGVGVSKASCCCSLG 1567
Score = 111 bits (277), Expect = 3e-24
Identities = 72/248 (29%), Positives = 98/248 (39%), Gaps = 31/248 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN ++C C P F L G+ CK E C+ G
Sbjct: 582 CLNGMCINEDGSFKCICKPGFQLASDGRYCKDINE------------------CETPG-- 621
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCI---------- 459
+C NGRC+ + SY C+C G DG++C D +T RG CI
Sbjct: 622 ICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKS 681
Query: 460 --------------------NSPGSYQCSCYDGFTIHNMPGGPKC-YDRNECSEDKSLCK 576
+ YQ C G PG D NEC+ D +C
Sbjct: 682 ECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG------PGMTSAGSDINECALDPDICP 735
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT 756
NG+C N+ G++KC CNSGY S ++C+ I + S + DN + C G+
Sbjct: 736 NGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ--------CRNTPGS 787
Query: 757 FKCSCPYG 780
F C+CP G
Sbjct: 788 FVCTCPKG 795
Score = 108 bits (270), Expect = 2e-23
Identities = 77/305 (25%), Positives = 104/305 (34%), Gaps = 88/305 (28%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFN--LKS 285
C+ GRC+N + Y CEC F C TE N +S+ N KS
Sbjct: 2302 CENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 286 QCDKFGSF------------------------------------------LCKNGRCIES 339
+C G +C+NG C+
Sbjct: 2362 ECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVND 2421
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIH--- 510
SY C C G+ G C D++EC P C+ C N+ GSYQCSC G+ +
Sbjct: 2422 RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-FICKNTEGSYQCSCPKGYILQEDG 2480
Query: 511 ---------------------NMPGG-------------PKCYDRNECSEDKSLC-KNGV 585
N GG C D NEC+ D +LC G+
Sbjct: 2481 RSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGI 2540
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC 765
C N GSF C+C G+ C + D + +C H C + G ++C
Sbjct: 2541 CQNTPGSFTCECQRGFSLDQTGSSCEDV----------DECEGNHRCQHGCQNIIGGYRC 2590
Query: 766 SCPYG 780
SCP G
Sbjct: 2591 SCPQG 2595
Score = 103 bits (258), Expect = 5e-22
Identities = 65/233 (27%), Positives = 91/233 (39%), Gaps = 21/233 (9%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMN------DAASSFNLK-------- 282
C N + Y+C C ++L + G++CK E Q N + F K
Sbjct: 2459 CKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQH 2518
Query: 283 -------SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTIC 441
++C + G C + S+ C+C GF G C D+DEC N C
Sbjct: 2519 HTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHR-C 2577
Query: 442 DRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
G C N G Y+CSC G+ H +C D NEC +C C N GS+KC C
Sbjct: 2578 QHG-CQNIIGGYRCSCPQGYLQHYQ--WNQCVDENECL-SAHICGGASCHNTLGSYKCMC 2633
Query: 622 NSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+G+ C I + A CS+ C+ G + C CP G
Sbjct: 2634 PAGFQYEQFSGGCQDINECGSAQA---------PCSYGCSNTEGGYLCGCPPG 2677
Score = 102 bits (253), Expect = 2e-21
Identities = 56/173 (32%), Positives = 88/173 (50%), Gaps = 1/173 (0%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT-NPTICDRGTCINSPGSYQCS 486
+CK+G+CI + SY C+C G+ + G C D DEC+ NP C GTC N G ++C+
Sbjct: 2136 VCKHGQCINTDGSYRCECPFGYTLA--GNECVDTDECSVGNP--CGNGTCKNVIGGFECT 2191
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C +GF M C D NEC+++ LC C+N +GS++C+C GYV +++ C
Sbjct: 2192 CEEGFEPGPMM---TCEDINECAQNPLLCAFR-CVNTYGSYECKCPVGYVLREDRRMC-- 2245
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQ 825
D ++ C++ C + GT+ C C G + D C ++
Sbjct: 2246 ----KDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENE 2294
Score = 96.7 bits (239), Expect = 8e-20
Identities = 70/282 (24%), Positives = 99/282 (35%), Gaps = 69/282 (24%)
Frame = +1
Query: 142 RCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKN 321
RC+N Y C+C +VL + + CK E + K C + K
Sbjct: 2220 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEG-----------KHDCTE------KQ 2262
Query: 322 GRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGF 501
C +Y C C G+Q DG+ C D +EC T P IC+ G C+N+ GSY C C DGF
Sbjct: 2263 MECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGF 2322
Query: 502 TIHNMPGGPKCYD--------------------------RNECSED-------------- 561
T P +C D ++EC D
Sbjct: 2323 TA--SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPF 2380
Query: 562 ------KSLCKNG------------------VC-----INIHGSFKCQCNSGYVASSNKQ 654
K LC +G VC +N GS+ C C +GY
Sbjct: 2381 QGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT 2440
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
C+ + + + C+ C G+++CSCP G
Sbjct: 2441 SCVDLNECNQAP---------KPCNFICKNTEGSYQCSCPKG 2473
Score = 94.7 bits (234), Expect = 3e-19
Identities = 67/263 (25%), Positives = 104/263 (39%), Gaps = 22/263 (8%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFNLKS 285
E C G C N + ++C C F L G+ C+ +++ + + S + K
Sbjct: 2022 EICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQ 2081
Query: 286 QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDG--KICS--------------DIDE 417
+C C C G + C L E + +IC D+DE
Sbjct: 2082 EC-------C----CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130
Query: 418 CTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINI 597
C P +C G CIN+ GSY+C C G+T+ G +C D +ECS C NG C N+
Sbjct: 2131 CK-EPDVCKHGQCINTDGSYRCECPFGYTL----AGNECVDTDECSVGNP-CGNGTCKNV 2184
Query: 598 HGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPY 777
G F+C C G+ C I + + + C+ C G+++C CP
Sbjct: 2185 IGGFECTCEEGFEPGP-MMTCEDINECAQNPLL---------CAFRCVNTYGSYECKCPV 2234
Query: 778 GMESILDTGLCAPNSQIVDVQFD 846
G D +C + + + D
Sbjct: 2235 GYVLREDRRMCKDEDECEEGKHD 2257
Score = 89.4 bits (220), Expect = 1e-17
Identities = 69/276 (25%), Positives = 102/276 (36%), Gaps = 59/276 (21%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N++ Y+C C + +D G+ C E N S
Sbjct: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN-------------------SL 774
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNP------------------- 432
LC NG+C + S+ C C GF D K C DIDEC ++P
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSS 834
Query: 433 --------TICD---RGTCINSPGSYQCSC-YDGFTI----------------------- 507
TIC +GTC + +C +G T+
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDP 894
Query: 508 -----HNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQ 672
++ G +C D +EC +CKNG+C+N GSFKCQC SG + + C+ I+
Sbjct: 895 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIR 954
Query: 673 DSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ + +D +C+ A + C C G
Sbjct: 955 LETCFLRYED-----EECTLPIAGRHRMDACCCSVG 985
Score = 89.0 bits (219), Expect = 2e-17
Identities = 60/225 (26%), Positives = 94/225 (41%), Gaps = 10/225 (4%)
Frame = +1
Query: 136 GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLC 315
GGRC+ RC C F G C++ +Y+ S+ + Q G
Sbjct: 157 GGRCVAPN---RCACTYGFT----GPQCER--DYRTGPCFTVISNQMCQGQLS--GIVCT 205
Query: 316 KNGRCIESGSSYECKCNL----------GFQESSDGKICSDIDECTTNPTICDRGTCINS 465
K C G ++ C + GF + C D+DEC P +C G CIN+
Sbjct: 206 KQLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINT 265
Query: 466 PGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASS 645
GS++C C G ++ + KC D +ECS +C+ G C N S+ C+C G+ S
Sbjct: 266 VGSFECKCPAGHKLNEV--SQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSP 323
Query: 646 NKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ CI ++ Y+A+ + +CS+ +C C G
Sbjct: 324 DGTRCIDVRPGYCYTALTN-----GRCSNQLPQSITKMQCCCDAG 363
Score = 89.0 bits (219), Expect = 2e-17
Identities = 65/256 (25%), Positives = 101/256 (39%), Gaps = 29/256 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK-PNQMNDAASSFNLKSQCDKFGS 306
C G+C+N YRCEC FV G+AC+ E PN
Sbjct: 1415 CGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPN-------------------- 1454
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+C G C + C+C +G++ G C+D++EC +PT C G C+N+PGSY C
Sbjct: 1455 -ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICD 1512
Query: 487 CYDGFTIHNMPGG------PKCY--DRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
C F ++ G CY R + C N + + + C C+ G
Sbjct: 1513 CPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGV-SKASCCCSLGKAWG 1571
Query: 643 SNKQDCISIQDSSDYSA-------------------VDDNSKYCSKC-SHYCAFVNGTFK 762
+ + C ++ ++S+Y +D+ + C C G+F+
Sbjct: 1572 TPCEMCPAV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQ 1630
Query: 763 CSCPYGMESILDTGLC 810
C CP G DT +C
Sbjct: 1631 CRCPTGYYLNEDTRVC 1646
Score = 88.2 bits (217), Expect = 3e-17
Identities = 58/219 (26%), Positives = 89/219 (40%), Gaps = 23/219 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRT------EYKPNQMNDAASSFNLKSQC 291
C G C+N Y C+C PDF L+ C + +P N + N
Sbjct: 1497 CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSN----- 1551
Query: 292 DKFGSFLCKNGRCIESGSSYECKCNL-----------------GFQESSDGKICSDIDEC 420
+ G + K C G ++ C + GF+ + I DIDEC
Sbjct: 1552 -EIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDEC 1610
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIH 600
P +C G CIN+ GS+QC C G+ ++ C D NEC E +C G C N
Sbjct: 1611 QELPGLCQGGKCINTFGSFQCRCPTGYYLNE--DTRVCDDVNEC-ETPGICGPGTCYNTV 1667
Query: 601 GSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYC 717
G++ C C Y+ + +C+ ++ S Y +++ C
Sbjct: 1668 GNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 84.3 bits (207), Expect = 4e-16
Identities = 52/165 (31%), Positives = 70/165 (42%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C N + CEC F LD+ G +C+ E C+ G+ C+
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQTGSSCEDVDE------------------CE--GNHRCQ 2578
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C Y C C G+ + C D +EC + IC +C N+ GSY+C C G
Sbjct: 2579 HG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAG 2636
Query: 499 FTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGY 633
F GG C D NEC ++ C G C N G + C C GY
Sbjct: 2637 FQYEQFSGG--CQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
Score = 81.3 bits (199), Expect = 3e-15
Identities = 43/133 (32%), Positives = 65/133 (48%)
Frame = +1
Query: 412 DECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCI 591
D C +C G CI +PGSY+C C GF + ++ G +C D +EC +K+ C G CI
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL-DLRG--ECIDVDEC--EKNPCAGGECI 505
Query: 592 NIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
N GS+ CQC +GY ++ + +C I + + +N + C +G+F C C
Sbjct: 506 NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGR--------CINTDGSFHCVC 557
Query: 772 PYGMESILDTGLC 810
G D C
Sbjct: 558 NAGFHVTRDGKNC 570
Score = 80.1 bits (196), Expect = 8e-15
Identities = 52/166 (31%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Frame = +1
Query: 103 CSFSYYSEQC----KGGRCINMKNQYRCEC-LPDFVLDKQ------GQACKKRTEYKPNQ 249
C++ + QC + G C + + C+ L V KQ G+A E P Q
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVGRAWGHPCEMCPAQ 227
Query: 250 MNDAASSF--NLKS-------QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKIC 402
+ F N+++ +C LC+ G CI + S+ECKC G + + + C
Sbjct: 228 PHPCRRGFIPNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKLNEVSQKC 286
Query: 403 SDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYD 540
DIDEC+T P IC+ G C N+ SY C C GF + P G +C D
Sbjct: 287 EDIDECSTIPGICEGGECTNTVSSYFCKCPPGF--YTSPDGTRCID 330
Score = 79.0 bits (193), Expect = 2e-14
Identities = 62/271 (22%), Positives = 98/271 (36%), Gaps = 35/271 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG+CIN ++C C + L++ + C E C+ G
Sbjct: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE------------------CETPG-- 1656
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE--CTTN----PTICDRGTCINSPG 471
+C G C + +Y C C + + + G C D+ C N CD N
Sbjct: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTK 1716
Query: 472 SYQCSCYD-----------------------------GFTIHNMPGGPKCYDRNECSEDK 564
C Y+ GF I G P D +EC E
Sbjct: 1717 KMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP--VDIDECREIP 1774
Query: 565 SLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF 744
+C+NGVCIN+ GSF+C+C G+ + C I + + N++ C
Sbjct: 1775 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE--------CIN 1826
Query: 745 VNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
G+++C C G TG C ++ ++
Sbjct: 1827 TAGSYRCDCKPGYR-FTSTGQCNDRNECQEI 1856
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/194 (25%), Positives = 78/194 (40%), Gaps = 24/194 (12%)
Frame = +1
Query: 301 GSFLCKNGRCIESG---SSYECKCNLGF---QESSDGK-------ICSDIDECTTNPTIC 441
G +C++G C+ G + C C GF Q D + I + + + + +C
Sbjct: 146 GQPVCESG-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 442 DRGTCINSPG---SYQCS--------CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVC 588
+ C + G + C C GF I N+ G C D +EC LC+ G C
Sbjct: 205 TKQLCCATVGRAWGHPCEMCPAQPHPCRRGF-IPNIRTGA-CQDVDECQAIPGLCQGGNC 262
Query: 589 INIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCS 768
IN GSF+C+C +G+ + Q C I + S + + + C ++ C
Sbjct: 263 INTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGE--------CTNTVSSYFCK 314
Query: 769 CPYGMESILDTGLC 810
CP G + D C
Sbjct: 315 CPPGFYTSPDGTRC 328
>sp|P98133|FBN1_BOVIN Fibrillin-1 precursor (MP340)
Length = 2871
Score = 138 bits (347), Expect = 2e-32
Identities = 81/239 (33%), Positives = 100/239 (41%), Gaps = 22/239 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQ------------------MN 255
C+GG C+N + YRCEC P L AC E + + N
Sbjct: 1124 CRGGVCLNTEGSYRCECPPGHQLAPNISACIDINECELSAHLCPHGRCVNLIGKYQCACN 1183
Query: 256 DAASSFNLKSQCDKFGSFLCKNGRC----IESGSSYECKCNLGFQESSDGKICSDIDECT 423
S + C NG C S SYEC C GF D + C+DIDEC
Sbjct: 1184 PGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECE 1243
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
NP ICD G C N PG Y+C CYDGF C D NEC + ++C +G C N G
Sbjct: 1244 DNPNICDGGQCTNIPGEYRCLCYDGFMASE--DMKTCVDVNECDLNPNICLSGTCENTKG 1301
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
SF C C+ GY K C I + + D C+ + G+FKCSC G
Sbjct: 1302 SFICHCDMGYSGKKGKTGCTDINECEIGAHNCDRHAVCTNTA-------GSFKCSCSPG 1353
Score = 135 bits (341), Expect = 1e-31
Identities = 76/227 (33%), Positives = 105/227 (46%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ GRCI YRCEC F LD +G+ +C+K
Sbjct: 460 CQNGRCIPTPGSYRCECNKGFQLDLRGECIDV-------------------DECEKNP-- 498
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C G CI + SY C+C G+Q + C DIDEC N IC+ G CIN+ GS+ C C
Sbjct: 499 -CAGGECINTQGSYTCQCRPGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVC 557
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
GF H G C D +ECS +++C NG+CIN GSFKC C G+ +S+ + C I
Sbjct: 558 NAGF--HVTRDGKNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDI 614
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + C +G+++C C G+ LD +C
Sbjct: 615 NECETLGICMNGR---------CVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 134 bits (337), Expect = 3e-31
Identities = 77/243 (31%), Positives = 123/243 (50%), Gaps = 26/243 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLD------------KQGQACKK-----------RTEYK 240
C+ G CINM +RCEC F + + G C++ R + K
Sbjct: 1777 CENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCK 1836
Query: 241 PNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDEC 420
P + N +++C + + +C +G+CI++ S+ C C+ GF+ ++D +C DI+EC
Sbjct: 1837 PGYRFTSTGQCNDRNECQEIPN-ICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDINEC 1895
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTI-HNMPGGPKCYDRNECSEDK-SLCKNGVCIN 594
+ C GTC N+ GS+ C C GF + HN C D +EC+ +LC+NG CIN
Sbjct: 1896 ERDA--CGNGTCRNTIGSFNCRCNHGFILSHNND----CIDVDECATGNGNLCRNGQCIN 1949
Query: 595 IHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSC 771
GSF+CQCN GY + + + C+ I + +D KC+ C ++G+++C C
Sbjct: 1950 TVGSFQCQCNEGYEVAPDGRTCVDINEC----LLDPR-----KCAPGTCQNLDGSYRCIC 2000
Query: 772 PYG 780
P G
Sbjct: 2001 PPG 2003
Score = 131 bits (330), Expect = 2e-30
Identities = 72/242 (29%), Positives = 106/242 (43%), Gaps = 7/242 (2%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C N ++C C F LD + + C E +
Sbjct: 1039 CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECR-------------------ISPD 1079
Query: 310 LCKNGRCIESGSSYECKCNLGFQES-SDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
LC G+C+ + +ECKC+ G++ K C DIDEC +P +C G C+N+ GSY+C
Sbjct: 1080 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCLNTEGSYRCE 1139
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G + P C D NEC LC +G C+N+ G ++C CN GY ++ ++ C+
Sbjct: 1140 CPPGHQL--APNISACIDINECELSAHLCPHGRCVNLIGKYQCACNPGYHSTPDRLFCVD 1197
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG------MESILDTGLCAPNSQI 828
I D+ S C +C G+++CSC G S D C N I
Sbjct: 1198 I---------DECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI 1248
Query: 829 VD 834
D
Sbjct: 1249 CD 1250
Score = 129 bits (323), Expect = 1e-29
Identities = 69/216 (31%), Positives = 101/216 (46%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
+ C G C N + C C F+L ND +C
Sbjct: 1898 DACGNGTCRNTIGSFNCRCNHGFILSHN---------------NDCIDV----DECATGN 1938
Query: 304 SFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQC 483
LC+NG+CI + S++C+CN G++ + DG+ C DI+EC +P C GTC N GSY+C
Sbjct: 1939 GNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLDPRKCAPGTCQNLDGSYRC 1998
Query: 484 SCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCI 663
C G+++ N KC D +EC E+ +C G C N GSFKC C G+ SS + C
Sbjct: 1999 ICPPGYSLQN----DKCEDIDECVEEPEICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQ 2054
Query: 664 SIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
++ S Y+ + KCS + + +C C
Sbjct: 2055 DLRMSYCYAKFEG-----GKCSSPKSRNHSKQECCC 2085
Score = 127 bits (320), Expect = 3e-29
Identities = 66/214 (30%), Positives = 108/214 (50%), Gaps = 1/214 (0%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE P + + C + + ++ + F ++C + LC +G+C + S+
Sbjct: 993 CEECPVRNTPEYEELCPRGPGFATKEITNGKRFFKDINECKMIPN-LCTHGKCRNTIGSF 1051
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
+C+C+ GF S+ + C+DIDEC +P +C RG C+N+PG ++C C +G+ M
Sbjct: 1052 KCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMM-MKN 1110
Query: 532 CYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSK 711
C D +EC D LC+ GVC+N GS++C+C G+ + N CI I + + SA
Sbjct: 1111 CMDIDECQRDPLLCRGGVCLNTEGSYRCECPPGHQLAPNISACIDINE-CELSA------ 1163
Query: 712 YCSKCSH-YCAFVNGTFKCSCPYGMESILDTGLC 810
C H C + G ++C+C G S D C
Sbjct: 1164 --HLCPHGRCVNLIGKYQCACNPGYHSTPDRLFC 1195
Score = 122 bits (307), Expect = 1e-27
Identities = 65/179 (36%), Positives = 93/179 (51%)
Frame = +1
Query: 274 NLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGT 453
N+ C F +LC+NGRCI + SY C+CN GFQ G+ C D+DEC NP C G
Sbjct: 448 NVTDYCQLF-RYLCQNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGE 503
Query: 454 CINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGY 633
CIN+ GSY C C G+ + +C D +EC ++ +C NG CIN GSF C CN+G+
Sbjct: 504 CINTQGSYTCQCRPGY--QSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGF 561
Query: 634 VASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + ++C + + S + + C +G+FKC C G + D C
Sbjct: 562 HVTRDGKNCEDMDECSIRNMC---------LNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 120 bits (301), Expect = 5e-27
Identities = 78/279 (27%), Positives = 121/279 (43%), Gaps = 36/279 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF-GS 306
C GG+C N+ +YRC C F+ + + C E D + L C+ GS
Sbjct: 1249 CDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNEC------DLNPNICLSGTCENTKGS 1302
Query: 307 FLC--------KNGR---------------------CIESGSSYECKCNLGFQESSDGKI 399
F+C K G+ C + S++C C+ G+ DG
Sbjct: 1303 FICHCDMGYSGKKGKTGCTDINECEIGAHNCDRHAVCTNTAGSFKCSCSPGW--IGDGIK 1360
Query: 400 CSDIDECTTNPTICDR-GTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCK 576
C+D+DEC+ +C + C N+ GSY+C C +G+T G C D +ECSE+ +LC
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT----GDGFTCTDLDECSENLNLCG 1416
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF---- 744
NG C+N G ++C+C+ G+V S++ + C I + S + C F
Sbjct: 1417 NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECS--------------LPNICVFGTCH 1462
Query: 745 -VNGTFKCSCPYGMESILDTGLCAPNSQIVDVQFDIPNN 858
+ G F+C C G E G C ++ +D I N
Sbjct: 1463 NLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGN 1501
Score = 116 bits (291), Expect = 7e-26
Identities = 75/241 (31%), Positives = 99/241 (41%), Gaps = 50/241 (20%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACK------------KR--------------- 228
C GRC+N YRCEC P + G+ C KR
Sbjct: 623 CMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCVKPLFGAVTKSE 682
Query: 229 -----TEY---KPNQMNDAASSFNLKSQCDKFGSF---------------LCKNGRCIES 339
TEY +P Q + +S ++ C +C NG C
Sbjct: 683 CCCASTEYAFGEPCQPCPSQNSAEYQALCSSGPGITSAGSDINECALDPDICPNGICENL 742
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
+Y+C CN G++ S GK C DI+EC N +CD G C N+PGS+ C+C GF P
Sbjct: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY--KP 800
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVD 699
C D +EC + S C NGVC N GSF C+C+S K CI + + V
Sbjct: 801 ELKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI 858
Query: 700 D 702
D
Sbjct: 859 D 859
Score = 116 bits (290), Expect = 9e-26
Identities = 74/261 (28%), Positives = 105/261 (40%), Gaps = 34/261 (13%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G C+N + Y C C +T Y P+ A N +Q K +F
Sbjct: 2413 CRNGECVNDRGSYHCIC---------------KTGYTPDITGTACVDLNECNQAPKPCNF 2457
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+CKN + SY+C C G+ DG+ C D+DEC T C + C+N+ GS+ C C
Sbjct: 2458 ICKN-----TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGSFTCKC 2511
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLC-KNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
GFT H+ C D NEC+ D +LC G+C N GSF C+C G+ C
Sbjct: 2512 PPGFTQHHTA----CIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDPTGASCED 2567
Query: 667 IQDSSDY-----------------------------SAVDDN----SKYCSKCSHYCAFV 747
+ + VD+N + C S C
Sbjct: 2568 VDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGAS--CHNT 2625
Query: 748 NGTFKCSCPYGMESILDTGLC 810
G++KC CP G + +G C
Sbjct: 2626 LGSYKCMCPAGFQYEQFSGGC 2646
Score = 115 bits (289), Expect = 1e-25
Identities = 69/227 (30%), Positives = 100/227 (44%), Gaps = 3/227 (1%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNG 324
C N YRC C + D G C +++ + + NL C NG
Sbjct: 1380 CKNTMGSYRCLCKEGYTGD--GFTC--------TDLDECSENLNL-----------CGNG 1418
Query: 325 RCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFT 504
+C+ + Y C+C++GF S+DGK C DIDEC+ P IC GTC N PG ++C C G+
Sbjct: 1419 QCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYE 1477
Query: 505 IHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSD 684
+ G C D NEC D + C +G C+N GS+ C C + + + C+ + +
Sbjct: 1478 LDR--SGGNCTDVNECL-DPTTCISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNC 1534
Query: 685 YSAV---DDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAP 816
Y + DN + CS+ C C G LC P
Sbjct: 1535 YLDIRPRGDNGD--TACSNEIGVGVSKASCCCSLGKAWGTPCELCPP 1579
Score = 115 bits (287), Expect = 2e-25
Identities = 76/294 (25%), Positives = 113/294 (38%), Gaps = 58/294 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKK-------RTEYKPNQMNDAASSFNL-KS 285
C G C N Y C C PD++ G C R Y NQ D FN+ K
Sbjct: 1658 CGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKK 1717
Query: 286 QC----------------------DKFGSF----------------------------LC 315
C D+F + +C
Sbjct: 1718 MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC 1777
Query: 316 KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYD 495
+NG CI S+ C+C +GF + +C DIDEC P CIN+ GSY+C C
Sbjct: 1778 ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP 1837
Query: 496 GFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQD 675
G+ +C DRNEC E ++C +G CI+ GSF C C++G+ ++++ C+ I +
Sbjct: 1838 GY---RFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDINE 1894
Query: 676 SSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
+ + C G+F C C +G + + N+ +DV
Sbjct: 1895 CERDACGNGT----------CRNTIGSFNCRCNHGF-------ILSHNNDCIDV 1931
Score = 112 bits (280), Expect = 1e-24
Identities = 70/247 (28%), Positives = 98/247 (39%), Gaps = 30/247 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN ++C C P F L G+ CK E C+ G
Sbjct: 582 CLNGMCINEDGSFKCICKPGFQLASDGRYCKDINE------------------CETLG-- 621
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCI---------- 459
+C NGRC+ + SY C+C G DG++C D +T RG C+
Sbjct: 622 ICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCVKPLFGAVTKS 681
Query: 460 --------------------NSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKN 579
+ YQ C G I + D NEC+ D +C N
Sbjct: 682 ECCCASTEYAFGEPCQPCPSQNSAEYQALCSSGPGITSAGS-----DINECALDPDICPN 736
Query: 580 GVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTF 759
G+C N+ G++KC CNSGY S ++C+ I + S + DN + C G+F
Sbjct: 737 GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ--------CRNTPGSF 788
Query: 760 KCSCPYG 780
C+CP G
Sbjct: 789 VCTCPKG 795
Score = 112 bits (279), Expect = 2e-24
Identities = 66/234 (28%), Positives = 90/234 (38%), Gaps = 42/234 (17%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
CK G+CIN YRCEC ++L QG C E
Sbjct: 2137 CKHGQCINTDGSYRCECPFGYIL--QGNECVDTDECSVGNP------------------- 2175
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C NG C +EC C GF E C DI+EC NP +C C+N+ GSY+C C
Sbjct: 2176 -CGNGTCKNVIGGFECTCEEGF-EPGPMMTCEDINECAQNPLLC-AFRCVNTYGSYECKC 2232
Query: 490 YDGFTI------------------------------------------HNMPGGPKCYDR 543
G+ + P G C D
Sbjct: 2233 PAGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGTYLCICGPGYQRRPDGEGCVDE 2292
Query: 544 NECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDN 705
NEC +C+NG C+N GS+ C+CN G+ AS N+ +C+ ++ ++ V N
Sbjct: 2293 NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQN 2346
Score = 107 bits (268), Expect = 3e-23
Identities = 78/305 (25%), Positives = 106/305 (34%), Gaps = 88/305 (28%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFN--LKS 285
C+ GRC+N + Y CEC F C TE N +S+ N KS
Sbjct: 2302 CENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 286 QCDKFGSF------------------------------------------LCKNGRCIES 339
+C G +C+NG C+
Sbjct: 2362 ECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVND 2421
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTI---- 507
SY C C G+ G C D++EC P C+ C N+ GSYQCSC G+ +
Sbjct: 2422 RGSYHCICKTGYTPDITGTACVDLNECNQAPKPCN-FICKNTEGSYQCSCPKGYILQEDG 2480
Query: 508 -------------HNM----------------PGGPK----CYDRNECSEDKSLC-KNGV 585
HN PG + C D NEC+ D +LC G+
Sbjct: 2481 RSCKDLDECATKQHNCQFLCVNTIGSFTCKCPPGFTQHHTACIDNNECTSDINLCGSKGI 2540
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC 765
C N GSF C+C G+ C + D + +C H C + G ++C
Sbjct: 2541 CQNTPGSFTCECQRGFSLDPTGASCEDV----------DECEGNHRCQHGCQNIIGGYRC 2590
Query: 766 SCPYG 780
SCP G
Sbjct: 2591 SCPQG 2595
Score = 105 bits (261), Expect = 2e-22
Identities = 66/233 (28%), Positives = 93/233 (39%), Gaps = 21/233 (9%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMN------DAASSFNLK-------- 282
C N + Y+C C ++L + G++CK E Q N + SF K
Sbjct: 2459 CKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGSFTCKCPPGFTQH 2518
Query: 283 -------SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTIC 441
++C + G C + S+ C+C GF G C D+DEC N C
Sbjct: 2519 HTACIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDPTGASCEDVDECEGNHR-C 2577
Query: 442 DRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
G C N G Y+CSC G+ H +C D NEC +C C N GS+KC C
Sbjct: 2578 QHG-CQNIIGGYRCSCPQGYLQHYQ--WNQCVDENECL-SAHICGGASCHNTLGSYKCMC 2633
Query: 622 NSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+G+ C I + A CS+ C+ G + C+CP G
Sbjct: 2634 PAGFQYEQFSGGCQDINECGSAQA---------PCSYGCSNTEGGYLCACPPG 2677
Score = 95.5 bits (236), Expect = 2e-19
Identities = 70/282 (24%), Positives = 100/282 (35%), Gaps = 69/282 (24%)
Frame = +1
Query: 142 RCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKN 321
RC+N Y C+C +VL + + CK E + + + A CKN
Sbjct: 2220 RCVNTYGSYECKCPAGYVLREDRRMCKDEDECEEGKHDCAEKQME------------CKN 2267
Query: 322 GRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGF 501
+Y C C G+Q DG+ C D +EC T P IC+ G C+N+ GSY C C DGF
Sbjct: 2268 -----LIGTYLCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGF 2322
Query: 502 TIHNMPGGPKCYD--------------------------RNECSED-------------- 561
T P +C D ++EC D
Sbjct: 2323 TA--SPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPF 2380
Query: 562 ------KSLCKNG------------------VC-----INIHGSFKCQCNSGYVASSNKQ 654
K LC +G VC +N GS+ C C +GY
Sbjct: 2381 QGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGT 2440
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
C+ + + + C+ C G+++CSCP G
Sbjct: 2441 ACVDLNECNQAP---------KPCNFICKNTEGSYQCSCPKG 2473
Score = 91.7 bits (226), Expect = 3e-18
Identities = 66/263 (25%), Positives = 103/263 (39%), Gaps = 22/263 (8%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFNLKS 285
E C G C N + ++C C F L G+ C+ +++ + + S + K
Sbjct: 2022 EICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQ 2081
Query: 286 QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDG--KICS--------------DIDE 417
+C C C G + C L E + +IC D+DE
Sbjct: 2082 EC-------C----CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130
Query: 418 CTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINI 597
C P +C G CIN+ GSY+C C G+ + G +C D +ECS C NG C N+
Sbjct: 2131 CK-EPDVCKHGQCINTDGSYRCECPFGYILQ----GNECVDTDECSVGNP-CGNGTCKNV 2184
Query: 598 HGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPY 777
G F+C C G+ C I + + + C+ C G+++C CP
Sbjct: 2185 IGGFECTCEEGFEPGP-MMTCEDINECAQNPLL---------CAFRCVNTYGSYECKCPA 2234
Query: 778 GMESILDTGLCAPNSQIVDVQFD 846
G D +C + + + D
Sbjct: 2235 GYVLREDRRMCKDEDECEEGKHD 2257
Score = 89.7 bits (221), Expect = 1e-17
Identities = 59/219 (26%), Positives = 89/219 (40%), Gaps = 23/219 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRT------EYKPNQMNDAASSFNLKSQC 291
C G C+N Y C+C PDF L+ C + +P N + N
Sbjct: 1497 CISGNCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSN----- 1551
Query: 292 DKFGSFLCKNGRCIESGSSYECKCNL-----------------GFQESSDGKICSDIDEC 420
+ G + K C G ++ C L GF+ + I DIDEC
Sbjct: 1552 -EIGVGVSKASCCCSLGKAWGTPCELCPPVNTSEYKILCPGGEGFRPNPITVILEDIDEC 1610
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIH 600
P +C G CIN+ GS+QC C G+ ++ C D NEC E +C G C N
Sbjct: 1611 QELPGLCQGGKCINTFGSFQCRCPTGYYLNE--DTRVCDDVNEC-ETPGICGPGTCYNTV 1667
Query: 601 GSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYC 717
G++ C C Y+ + +C+ ++ S Y +++ C
Sbjct: 1668 GNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 88.6 bits (218), Expect = 2e-17
Identities = 65/256 (25%), Positives = 100/256 (39%), Gaps = 29/256 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK-PNQMNDAASSFNLKSQCDKFGS 306
C G+C+N YRCEC FV G+AC+ E PN
Sbjct: 1415 CGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPN-------------------- 1454
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+C G C + C+C +G++ G C+D++EC +PT C G C+N+PGSY C
Sbjct: 1455 -ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYTCD 1512
Query: 487 CYDGFTIHNMPGG------PKCY--DRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
C F ++ G CY R + C N + + + C C+ G
Sbjct: 1513 CPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGV-SKASCCCSLGKAWG 1571
Query: 643 SNKQDCISIQDSSDYSA-------------------VDDNSKYCSKC-SHYCAFVNGTFK 762
+ + C + ++S+Y +D+ + C C G+F+
Sbjct: 1572 TPCELCPPV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQ 1630
Query: 763 CSCPYGMESILDTGLC 810
C CP G DT +C
Sbjct: 1631 CRCPTGYYLNEDTRVC 1646
Score = 87.0 bits (214), Expect = 6e-17
Identities = 68/276 (24%), Positives = 102/276 (36%), Gaps = 59/276 (21%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N++ Y+C C + +D G+ C E N S
Sbjct: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN-------------------SL 774
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNP------------------- 432
LC NG+C + S+ C C GF + K C DIDEC ++P
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPELKTCEDIDECESSPCINGVCKNSPGSFICECSS 834
Query: 433 --------TICD---RGTCINSPGSYQCSC-YDGFTI----------------------- 507
TIC +GTC + +C +G T+
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTPCQVDP 894
Query: 508 -----HNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQ 672
++ G +C D +EC +CKNG+C+N GSFKCQC SG + + C+ I+
Sbjct: 895 ICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNSKGSFKCQCPSGMTLDATGRICLDIR 954
Query: 673 DSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ + +D +C+ A + C C G
Sbjct: 955 LETCFLRYED-----EECTLPVAGRHRMDACCCSVG 985
Score = 83.6 bits (205), Expect = 7e-16
Identities = 52/165 (31%), Positives = 69/165 (41%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C N + CEC F LD G +C+ E C+ G+ C+
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDPTGASCEDVDE------------------CE--GNHRCQ 2578
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C Y C C G+ + C D +EC + IC +C N+ GSY+C C G
Sbjct: 2579 HG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAG 2636
Query: 499 FTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGY 633
F GG C D NEC ++ C G C N G + C C GY
Sbjct: 2637 FQYEQFSGG--CQDINECGSAQAPCSYG-CSNTEGGYLCACPPGY 2678
Score = 81.6 bits (200), Expect = 3e-15
Identities = 64/230 (27%), Positives = 94/230 (40%), Gaps = 24/230 (10%)
Frame = +1
Query: 103 CSFSYYSEQC----KGGRCINMKNQYRCE-------CLPDFVLDKQGQACKKRTEYKPNQ 249
C++ + QC + G C + + C+ C G+A E P Q
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ 227
Query: 250 MNDAASSF--NLKS-------QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKIC 402
+ F N+++ +C LC+ G CI + S+ECKC G + + + C
Sbjct: 228 PHPCRRGFIPNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKFNEVSQKC 286
Query: 403 SDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNG 582
DIDEC+T P ICD G C N+ SY C C GF + P G +C D +L NG
Sbjct: 287 EDIDECSTIPGICDGGECTNTVSSYFCKCPPGF--YTSPDGTRCIDVRPGYCYTALA-NG 343
Query: 583 VCIN----IHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCS 720
C N +C C++G S + A +D +K CS
Sbjct: 344 RCSNQLPQSITKMQCCCDAGRCWSPG---VTVAPEMCPIRATEDFNKLCS 390
Score = 79.0 bits (193), Expect = 2e-14
Identities = 62/271 (22%), Positives = 98/271 (36%), Gaps = 35/271 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG+CIN ++C C + L++ + C E C+ G
Sbjct: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE------------------CETPG-- 1656
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE--CTTN----PTICDRGTCINSPG 471
+C G C + +Y C C + + + G C D+ C N CD N
Sbjct: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTK 1716
Query: 472 SYQCSCYD-----------------------------GFTIHNMPGGPKCYDRNECSEDK 564
C Y+ GF I G P D +EC E
Sbjct: 1717 KMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP--VDIDECREIP 1774
Query: 565 SLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF 744
+C+NGVCIN+ GSF+C+C G+ + C I + + N++ C
Sbjct: 1775 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE--------CIN 1826
Query: 745 VNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
G+++C C G TG C ++ ++
Sbjct: 1827 TAGSYRCDCKPGYR-FTSTGQCNDRNECQEI 1856
Score = 61.6 bits (148), Expect = 3e-09
Identities = 42/139 (30%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQ-MNDAASSFN-----LK 282
S C G C N + CEC + LD C + + Q + D N LK
Sbjct: 813 SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLK 872
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECK----CNLGFQESSDGKICSDIDECTTNPTICDRG 450
SQC C + C+ C G+ G C DIDEC P +C G
Sbjct: 873 SQC-------CSSLGAAWGSPCTPCQVDPICGKGYSRIK-GTQCEDIDECEVFPGVCKNG 924
Query: 451 TCINSPGSYQCSCYDGFTI 507
C+NS GS++C C G T+
Sbjct: 925 LCVNSKGSFKCQCPSGMTL 943
Score = 57.4 bits (137), Expect = 5e-08
Identities = 50/194 (25%), Positives = 78/194 (40%), Gaps = 24/194 (12%)
Frame = +1
Query: 301 GSFLCKNGRCIESG---SSYECKCNLGF---QESSDGK-------ICSDIDECTTNPTIC 441
G +C++G C+ G + C C GF Q D + I + + + + +C
Sbjct: 146 GQPVCESG-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 442 DRGTCINSPG---SYQCS--------CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVC 588
+ C + G + C C GF I N+ G C D +EC LC+ G C
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGF-IPNIRTGA-CQDVDECQAIPGLCQGGNC 262
Query: 589 INIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCS 768
IN GSF+C+C +G+ + Q C I + S + D + C ++ C
Sbjct: 263 INTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGICDGGE--------CTNTVSSYFCK 314
Query: 769 CPYGMESILDTGLC 810
CP G + D C
Sbjct: 315 CPPGFYTSPDGTRC 328
>sp|Q9TV36|FBN1_PIG Fibrillin-1 precursor
Length = 2871
Score = 137 bits (344), Expect = 5e-32
Identities = 78/227 (34%), Positives = 108/227 (47%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C GRCI YRCEC F LD +G+ +C+K
Sbjct: 460 CHNGRCIPTPGSYRCECNKGFQLDLRGECIDV-------------------DECEKNP-- 498
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C G CI + SY C+C G+Q + C DIDEC N IC+ G CIN+ GS+ C C
Sbjct: 499 -CAGGECINNQGSYTCQCRPGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVC 557
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
GF H G C D +ECS +++C NG+CIN GSFKC C G+ +S+ + C I
Sbjct: 558 NAGF--HVTRDGKNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDI 614
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + S + N + C +G+++C C G+ LD +C
Sbjct: 615 NE-CETSGICMNGR--------CVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 133 bits (335), Expect = 6e-31
Identities = 78/239 (32%), Positives = 97/239 (40%), Gaps = 22/239 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK------------------PNQMN 255
C+GG C+N + YRCEC + AC E + N
Sbjct: 1124 CRGGVCLNTEGSYRCECPSGHQMSPNISACIDINECELSAHLCPHGRCVNLIGKYQRARN 1183
Query: 256 DAASSFNLKSQCDKFGSFLCKNGRC----IESGSSYECKCNLGFQESSDGKICSDIDECT 423
S + C NG C S SYEC C GF D + C+DIDEC
Sbjct: 1184 PGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECE 1243
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
NP ICD G C N PG Y+C CYDGF C D NEC + ++C +G C N G
Sbjct: 1244 DNPNICDGGQCTNIPGEYRCLCYDGFMASE--DMKTCVDVNECDLNPNICLSGTCENTKG 1301
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
SF C C+ GY K C I + + D C+ + G+F CSC G
Sbjct: 1302 SFICHCDMGYSGKKGKTGCTDINECEIGAHNCDRHAVCTNTA-------GSFNCSCSPG 1353
Score = 133 bits (334), Expect = 8e-31
Identities = 76/243 (31%), Positives = 121/243 (49%), Gaps = 26/243 (10%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLD------------KQGQACKK-----------RTEYK 240
C+ G CINM +RCEC F + + G C++ R + K
Sbjct: 1777 CENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCK 1836
Query: 241 PNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDEC 420
P + N +++C + + +C +G+CI++ S+ C C+ GF+ ++D +C DI+EC
Sbjct: 1837 PGYRFTSTGQCNDRNECQEIPN-ICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDINEC 1895
Query: 421 TTNPTICDRGTCINSPGSYQCSCYDGFTI-HNMPGGPKCYDRNECSEDK-SLCKNGVCIN 594
+ C GTC N+ GS+ C C GF + HN C D +EC+ +LC+NG CIN
Sbjct: 1896 ERDA--CGNGTCRNTIGSFNCRCNHGFILSHNND----CIDVDECATGNGNLCRNGQCIN 1949
Query: 595 IHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSC 771
GSF+CQCN GY + + + C+ I + KC+ C ++G+++C C
Sbjct: 1950 TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPG---------KCAPGTCQNLDGSYRCIC 2000
Query: 772 PYG 780
P G
Sbjct: 2001 PPG 2003
Score = 128 bits (321), Expect = 2e-29
Identities = 69/216 (31%), Positives = 100/216 (46%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
+ C G C N + C C F+L ND +C
Sbjct: 1898 DACGNGTCRNTIGSFNCRCNHGFILSHN---------------NDCIDV----DECATGN 1938
Query: 304 SFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQC 483
LC+NG+CI + S++C+CN G++ + DG+ C DI+EC P C GTC N GSY+C
Sbjct: 1939 GNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPGKCAPGTCQNLDGSYRC 1998
Query: 484 SCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCI 663
C G+++ N KC D +EC E+ +C G C N GSFKC C G+ SS + C
Sbjct: 1999 ICPPGYSLQN----DKCEDIDECVEEPEICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQ 2054
Query: 664 SIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
++ S Y+ + KCS + + +C C
Sbjct: 2055 DLRMSYCYAKFEG-----GKCSSPKSRNHSKQECCC 2085
Score = 127 bits (319), Expect = 4e-29
Identities = 73/261 (27%), Positives = 115/261 (44%), Gaps = 40/261 (15%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE P + + C + + ++ + F ++C + LC +G+C + S+
Sbjct: 993 CEECPPRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPN-LCTHGKCRNTIGSF 1051
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
+C+C+ GF S+ + C DIDEC +P +C RG C+N+PG ++C C +G+ M
Sbjct: 1052 KCRCDSGFALDSEERNCIDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMM-KN 1110
Query: 532 CYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSA------ 693
C D +EC D LC+ GVC+N GS++C+C SG+ S N CI I + + SA
Sbjct: 1111 CMDIDECQRDPLLCRGGVCLNTEGSYRCECPSGHQMSPNISACIDINEC-ELSAHLCPHG 1169
Query: 694 ----------------------------VDDNSKYCSKCSHYCAFVNGTFKCSCPYG--- 780
+D+ S C +C G+++CSC G
Sbjct: 1170 RCVNLIGKYQRARNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 781 ---MESILDTGLCAPNSQIVD 834
S D C N I D
Sbjct: 1230 MPDQRSCTDIDECEDNPNICD 1250
Score = 122 bits (305), Expect = 2e-27
Identities = 65/179 (36%), Positives = 92/179 (51%)
Frame = +1
Query: 274 NLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGT 453
N+ C F +LC NGRCI + SY C+CN GFQ G+ C D+DEC NP C G
Sbjct: 448 NVTDYCQLF-RYLCHNGRCIPTPGSYRCECNKGFQLDLRGE-CIDVDECEKNP--CAGGE 503
Query: 454 CINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGY 633
CIN+ GSY C C G+ + +C D +EC ++ +C NG CIN GSF C CN+G+
Sbjct: 504 CINNQGSYTCQCRPGY--QSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGF 561
Query: 634 VASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + ++C + + S + + C +G+FKC C G + D C
Sbjct: 562 HVTRDGKNCEDMDECSIRNMC---------LNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 117 bits (292), Expect = 6e-26
Identities = 75/261 (28%), Positives = 106/261 (40%), Gaps = 34/261 (13%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G CIN + Y C C +T Y P+ A N +Q K +F
Sbjct: 2413 CRNGECINDRGSYHCIC---------------KTGYTPDITGTACVDLNECNQAPKPCNF 2457
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+CKN + SY+C C G+ DG+ C D+DEC T C + C+N+ GS+ C C
Sbjct: 2458 ICKN-----TEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGSFACKC 2511
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLC-KNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
GFT H+ C D NEC+ D +LC G+C N GSF C+C G+ + C
Sbjct: 2512 PPGFTQHHTA----CIDNNECTSDINLCGAKGICQNTPGSFTCECQRGFSLDQSGASCED 2567
Query: 667 IQDSSDY-----------------------------SAVDDN----SKYCSKCSHYCAFV 747
+ + VD+N + C S C
Sbjct: 2568 VDECEGNHRCQHGCQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGAS--CHNT 2625
Query: 748 NGTFKCSCPYGMESILDTGLC 810
G++KC CP G + +G C
Sbjct: 2626 LGSYKCMCPAGFQYEQFSGGC 2646
Score = 116 bits (291), Expect = 7e-26
Identities = 74/241 (30%), Positives = 99/241 (41%), Gaps = 50/241 (20%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACK------------KR--------------- 228
C GRC+N YRCEC P + G+ C KR
Sbjct: 623 CMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCVKPLFGAVTKSE 682
Query: 229 -----TEY---KPNQMNDAASSFNLKSQCDKFGSF---------------LCKNGRCIES 339
TEY +P Q + +S ++ C +C NG C
Sbjct: 683 CCCASTEYAFGEPCQPCPSQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENL 742
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
+Y+C CN G++ S GK C DI+EC N +CD G C N+PGS+ C+C GF P
Sbjct: 743 RGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY--KP 800
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVD 699
C D +EC + S C NGVC N GSF C+C+S K CI + + +
Sbjct: 801 DLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTII 858
Query: 700 D 702
D
Sbjct: 859 D 859
Score = 115 bits (287), Expect = 2e-25
Identities = 76/294 (25%), Positives = 113/294 (38%), Gaps = 58/294 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKK-------RTEYKPNQMNDAASSFNL-KS 285
C G C N Y C C PD++ G C R Y NQ D FN+ K
Sbjct: 1658 CGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKK 1717
Query: 286 QC----------------------DKFGSF----------------------------LC 315
C D+F + +C
Sbjct: 1718 MCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC 1777
Query: 316 KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYD 495
+NG CI S+ C+C +GF + +C DIDEC P CIN+ GSY+C C
Sbjct: 1778 ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP 1837
Query: 496 GFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQD 675
G+ +C DRNEC E ++C +G CI+ GSF C C++G+ ++++ C+ I +
Sbjct: 1838 GY---RFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNADQTMCLDINE 1894
Query: 676 SSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
+ + C G+F C C +G + + N+ +DV
Sbjct: 1895 CERDACGNGT----------CRNTIGSFNCRCNHGF-------ILSHNNDCIDV 1931
Score = 111 bits (278), Expect = 2e-24
Identities = 71/248 (28%), Positives = 98/248 (39%), Gaps = 31/248 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN ++C C P F L G+ CK E C+ G
Sbjct: 582 CLNGMCINEDGSFKCICKPGFQLASDGRYCKDINE------------------CETSG-- 621
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCI---------- 459
+C NGRC+ + SY C+C G DG++C D +T RG C+
Sbjct: 622 ICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCVKPLFGAVTKS 681
Query: 460 --------------------NSPGSYQCSCYDGFTIHNMPGGPKC-YDRNECSEDKSLCK 576
+ YQ C G PG D NEC+ D +C
Sbjct: 682 ECCCASTEYAFGEPCQPCPSQNSAEYQALCSSG------PGMTSAGSDINECALDPDICP 735
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT 756
NG+C N+ G++KC CNSGY S ++C+ I + S + DN + C G+
Sbjct: 736 NGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ--------CRNTPGS 787
Query: 757 FKCSCPYG 780
F C+CP G
Sbjct: 788 FVCTCPKG 795
Score = 109 bits (272), Expect = 1e-23
Identities = 73/274 (26%), Positives = 119/274 (43%), Gaps = 31/274 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF-GS 306
C GG+C N+ +YRC C F+ + + C E D + L C+ GS
Sbjct: 1249 CDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNEC------DLNPNICLSGTCENTKGS 1302
Query: 307 FLC--------KNGR---------------------CIESGSSYECKCNLGFQESSDGKI 399
F+C K G+ C + S+ C C+ G+ DG
Sbjct: 1303 FICHCDMGYSGKKGKTGCTDINECEIGAHNCDRHAVCTNTAGSFNCSCSPGW--IGDGIK 1360
Query: 400 CSDIDECTTNPTICDR-GTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCK 576
C+D+DEC+ +C + C N+ GSY+C C +G+T G C D +ECSE+ LC
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT----GDGFTCADLDECSENVKLCG 1416
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT 756
N C+ G + C+ + G+V S++++ C+ SD ++ + + + C + G
Sbjct: 1417 NVQCLYAPGGYHCEYDMGFVPSADRKSCV----DSDECSLPNICVFGT-----CHNLPGL 1467
Query: 757 FKCSCPYGMESILDTGLCAPNSQIVDVQFDIPNN 858
F+C C G E G C ++ ++ I N
Sbjct: 1468 FRCECEIGYELDRSGGNCTDVNECLEPPTCISGN 1501
Score = 108 bits (271), Expect = 2e-23
Identities = 64/234 (27%), Positives = 89/234 (38%), Gaps = 42/234 (17%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
CK G+CIN YRCEC ++L+ G C E
Sbjct: 2137 CKHGQCINTDGSYRCECPFGYILE--GNECVDTDECSVGNP------------------- 2175
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C NG C +EC C GF E C DI+EC NP +C C+N+ GSY+C C
Sbjct: 2176 -CGNGTCKNVIGGFECTCEEGF-EPGPMMTCEDINECAQNPLLC-AFRCVNTYGSYECKC 2232
Query: 490 YDGFTI------------------------------------------HNMPGGPKCYDR 543
G+ + P G C D
Sbjct: 2233 PTGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGMYICICGPGYQRRPDGEGCVDE 2292
Query: 544 NECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDN 705
NEC +C+NG C+N GS+ C+CN G+ AS + +C+ ++ ++ V N
Sbjct: 2293 NECQTKPGICENGRCLNTRGSYTCECNDGFTASPTQDECLDNREGYCFTEVLQN 2346
Score = 108 bits (269), Expect = 3e-23
Identities = 79/305 (25%), Positives = 107/305 (35%), Gaps = 88/305 (28%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFN--LKS 285
C+ GRC+N + Y CEC F C TE N +S+ N KS
Sbjct: 2302 CENGRCLNTRGSYTCECNDGFTASPTQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 286 QCDKFGSF------------------------------------------LCKNGRCIES 339
+C G +C+NG CI
Sbjct: 2362 ECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECIND 2421
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTI---- 507
SY C C G+ G C D++EC P C+ C N+ GSYQCSC G+ +
Sbjct: 2422 RGSYHCICKTGYTPDITGTACVDLNECNQAPKPCN-FICKNTEGSYQCSCPKGYILQEDG 2480
Query: 508 -------------HNM----------------PGGPK----CYDRNECSEDKSLC-KNGV 585
HN PG + C D NEC+ D +LC G+
Sbjct: 2481 RSCKDLDECATKQHNCQFLCVNTIGSFACKCPPGFTQHHTACIDNNECTSDINLCGAKGI 2540
Query: 586 CINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC 765
C N GSF C+C G+ + C + D + +C H C + G ++C
Sbjct: 2541 CQNTPGSFTCECQRGFSLDQSGASCEDV----------DECEGNHRCQHGCQNIIGGYRC 2590
Query: 766 SCPYG 780
SCP G
Sbjct: 2591 SCPQG 2595
Score = 104 bits (259), Expect = 4e-22
Identities = 68/239 (28%), Positives = 90/239 (37%), Gaps = 27/239 (11%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK-- 318
C N + Y+C C ++L + G++CK E Q N N GSF CK
Sbjct: 2459 CKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNT------IGSFACKCP 2512
Query: 319 -------------------------NGRCIESGSSYECKCNLGFQESSDGKICSDIDECT 423
G C + S+ C+C GF G C D+DEC
Sbjct: 2513 PGFTQHHTACIDNNECTSDINLCGAKGICQNTPGSFTCECQRGFSLDQSGASCEDVDECE 2572
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
N C G C N G Y+CSC G+ H +C D NEC +C C N G
Sbjct: 2573 GNHR-CQHG-CQNIIGGYRCSCPQGYLQHYQ--WNQCVDENECL-SAHICGGASCHNTLG 2627
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
S+KC C +G+ C I + A CS+ C+ G + C CP G
Sbjct: 2628 SYKCMCPAGFQYEQFSGGCQDINECGSSQA---------PCSYGCSNTEGGYLCGCPPG 2677
Score = 94.4 bits (233), Expect = 4e-19
Identities = 71/282 (25%), Positives = 99/282 (35%), Gaps = 69/282 (24%)
Frame = +1
Query: 142 RCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKN 321
RC+N Y C+C +VL + + CK E + + + A CKN
Sbjct: 2220 RCVNTYGSYECKCPTGYVLREDRRMCKDEDECEEGKHDCAEKQME------------CKN 2267
Query: 322 GRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGF 501
Y C C G+Q DG+ C D +EC T P IC+ G C+N+ GSY C C DGF
Sbjct: 2268 -----LIGMYICICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGF 2322
Query: 502 TIHNMPGGPKCYD--------------------------RNECSED-------------- 561
T P +C D ++EC D
Sbjct: 2323 TA--SPTQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPF 2380
Query: 562 ------KSLCKNG------------------VC-----INIHGSFKCQCNSGYVASSNKQ 654
K LC +G VC IN GS+ C C +GY
Sbjct: 2381 QGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECINDRGSYHCICKTGYTPDITGT 2440
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
C+ + + + C+ C G+++CSCP G
Sbjct: 2441 ACVDLNECNQAP---------KPCNFICKNTEGSYQCSCPKG 2473
Score = 91.7 bits (226), Expect = 3e-18
Identities = 66/263 (25%), Positives = 103/263 (39%), Gaps = 22/263 (8%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFNLKS 285
E C G C N + ++C C F L G+ C+ +++ + + S + K
Sbjct: 2022 EICALGTCSNTEGSFKCLCPDGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQ 2081
Query: 286 QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDG--KICS--------------DIDE 417
+C C C G + C L E + +IC D+DE
Sbjct: 2082 EC-------C----CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130
Query: 418 CTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINI 597
C P +C G CIN+ GSY+C C G+ + G +C D +ECS C NG C N+
Sbjct: 2131 CK-EPDVCKHGQCINTDGSYRCECPFGYILE----GNECVDTDECSVGNP-CGNGTCKNV 2184
Query: 598 HGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPY 777
G F+C C G+ C I + + + C+ C G+++C CP
Sbjct: 2185 IGGFECTCEEGFEPGP-MMTCEDINECAQNPLL---------CAFRCVNTYGSYECKCPT 2234
Query: 778 GMESILDTGLCAPNSQIVDVQFD 846
G D +C + + + D
Sbjct: 2235 GYVLREDRRMCKDEDECEEGKHD 2257
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/225 (26%), Positives = 92/225 (40%), Gaps = 10/225 (4%)
Frame = +1
Query: 136 GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLC 315
GGRC+ RC C F G C++ +Y+ S+ + Q G
Sbjct: 157 GGRCVAPN---RCACTYGFT----GPQCER--DYRTGPCFTVVSNQMCQGQLS--GIVCT 205
Query: 316 KNGRCIESGSSYECKCNL----------GFQESSDGKICSDIDECTTNPTICDRGTCINS 465
K C G ++ C + GF + C D+DEC P +C G CIN+
Sbjct: 206 KTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINT 265
Query: 466 PGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASS 645
GS++C C G + + KC D +ECS +C G C N S+ C+C G+ S
Sbjct: 266 VGSFECKCPAGHKFNEV--SQKCEDIDECSTIPGICDGGECTNTVSSYFCKCPPGFYTSP 323
Query: 646 NKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ CI ++ Y+A+ + +CS+ +C C G
Sbjct: 324 DGTRCIDVRPGYCYTALTN-----GRCSNQLPQSITKMQCCCDVG 363
Score = 87.0 bits (214), Expect = 6e-17
Identities = 68/253 (26%), Positives = 95/253 (37%), Gaps = 62/253 (24%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N++ Y+C C + +D G+ C E N S
Sbjct: 734 CPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN-------------------SL 774
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNP------------------- 432
LC NG+C + S+ C C GF D K C DIDEC ++P
Sbjct: 775 LCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSS 834
Query: 433 --------TICD---RGTC----------INSPG----SYQCS----------------- 486
TIC +GTC IN G S CS
Sbjct: 835 ESTLDPTKTICIETIKGTCWQTIIDGRCEININGATLKSQCCSSLGAAWGSPCTPCQVDP 894
Query: 487 -CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCI 663
C G++ G +C D +EC +CKNG+C+N GSFKCQC +G + + C+
Sbjct: 895 ICGKGYSRIK---GTQCEDIDECEVFPGVCKNGLCVNSKGSFKCQCPNGMTLDATGRICL 951
Query: 664 SIQDSSDYSAVDD 702
I+ + + +D
Sbjct: 952 DIRLETCFLRYED 964
Score = 87.0 bits (214), Expect = 6e-17
Identities = 63/214 (29%), Positives = 92/214 (42%), Gaps = 18/214 (8%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRT------EYKPNQMN-DAASSFNLKSQ 288
C G C+N Y C C PDF L+ C + +P N D A S +
Sbjct: 1497 CISGNCVNTPGSYTCVCPPDFELNPTRVGCVDTRSGNCYLDVRPRGDNGDTACSNEIGVG 1556
Query: 289 CDKFGSFLCKNGR-----CIE----SGSSYECKC--NLGFQESSDGKICSDIDECTTNPT 435
K S C G+ C + + S Y+ C GF+ + I DIDEC P
Sbjct: 1557 VSK-ASCCCSLGKAWGTPCEQCPPVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG 1615
Query: 436 ICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKC 615
+C G CIN+ GS+QC C G+ ++ C D NEC E +C G C N G++ C
Sbjct: 1616 LCQGGKCINTFGSFQCRCPTGYYLNE--DTRVCDDVNEC-ETPGICGPGTCYNTVGNYTC 1672
Query: 616 QCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYC 717
C Y+ + +C+ ++ S Y +++ C
Sbjct: 1673 ICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTC 1706
Score = 85.1 bits (209), Expect = 2e-16
Identities = 52/165 (31%), Positives = 70/165 (42%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C N + CEC F LD+ G +C+ E C+ G+ C+
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQSGASCEDVDE------------------CE--GNHRCQ 2578
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C Y C C G+ + C D +EC + IC +C N+ GSY+C C G
Sbjct: 2579 HG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAG 2636
Query: 499 FTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGY 633
F GG C D NEC ++ C G C N G + C C GY
Sbjct: 2637 FQYEQFSGG--CQDINECGSSQAPCSYG-CSNTEGGYLCGCPPGY 2678
Score = 81.6 bits (200), Expect = 3e-15
Identities = 50/166 (30%), Positives = 73/166 (43%), Gaps = 20/166 (12%)
Frame = +1
Query: 103 CSFSYYSEQC----KGGRCINMKNQYRCE-------CLPDFVLDKQGQACKKRTEYKPNQ 249
C++ + QC + G C + + C+ C G+A E P Q
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ 227
Query: 250 MNDAASSF--NLKS-------QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKIC 402
+ F N+++ +C LC+ G CI + S+ECKC G + + + C
Sbjct: 228 PHPCRRGFIPNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKFNEVSQKC 286
Query: 403 SDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYD 540
DIDEC+T P ICD G C N+ SY C C GF + P G +C D
Sbjct: 287 EDIDECSTIPGICDGGECTNTVSSYFCKCPPGF--YTSPDGTRCID 330
Score = 79.0 bits (193), Expect = 2e-14
Identities = 62/271 (22%), Positives = 98/271 (36%), Gaps = 35/271 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG+CIN ++C C + L++ + C E C+ G
Sbjct: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE------------------CETPG-- 1656
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE--CTTN----PTICDRGTCINSPG 471
+C G C + +Y C C + + + G C D+ C N CD N
Sbjct: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTK 1716
Query: 472 SYQCSCYD-----------------------------GFTIHNMPGGPKCYDRNECSEDK 564
C Y+ GF I G P D +EC E
Sbjct: 1717 KMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP--VDIDECREIP 1774
Query: 565 SLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF 744
+C+NGVCIN+ GSF+C+C G+ + C I + + N++ C
Sbjct: 1775 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE--------CIN 1826
Query: 745 VNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
G+++C C G TG C ++ ++
Sbjct: 1827 TAGSYRCDCKPGYR-FTSTGQCNDRNECQEI 1856
Score = 70.9 bits (172), Expect = 5e-12
Identities = 59/256 (23%), Positives = 93/256 (36%), Gaps = 29/256 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK-PNQMNDAASSFNLKSQCDKFGS 306
C +C+ Y CE FV ++C E PN
Sbjct: 1415 CGNVQCLYAPGGYHCEYDMGFVPSADRKSCVDSDECSLPN-------------------- 1454
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+C G C + C+C +G++ G C+D++EC PT C G C+N+PGSY C
Sbjct: 1455 -ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLEPPT-CISGNCVNTPGSYTCV 1512
Query: 487 CYDGFTIHNMPGG------PKCY--DRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
C F ++ G CY R + C N + + + C C+ G
Sbjct: 1513 CPPDFELNPTRVGCVDTRSGNCYLDVRPRGDNGDTACSNEIGVGV-SKASCCCSLGKAWG 1571
Query: 643 SNKQDCISIQDSSDYSA-------------------VDDNSKYCSKC-SHYCAFVNGTFK 762
+ + C + ++S+Y +D+ + C C G+F+
Sbjct: 1572 TPCEQCPPV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQ 1630
Query: 763 CSCPYGMESILDTGLC 810
C CP G DT +C
Sbjct: 1631 CRCPTGYYLNEDTRVC 1646
Score = 62.0 bits (149), Expect = 2e-09
Identities = 42/139 (30%), Positives = 56/139 (40%), Gaps = 10/139 (7%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQ-MNDAASSFN-----LK 282
S C G C N + CEC + LD C + + Q + D N LK
Sbjct: 813 SSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTIIDGRCEININGATLK 872
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECK----CNLGFQESSDGKICSDIDECTTNPTICDRG 450
SQC C + C+ C G+ G C DIDEC P +C G
Sbjct: 873 SQC-------CSSLGAAWGSPCTPCQVDPICGKGYSRIK-GTQCEDIDECEVFPGVCKNG 924
Query: 451 TCINSPGSYQCSCYDGFTI 507
C+NS GS++C C +G T+
Sbjct: 925 LCVNSKGSFKCQCPNGMTL 943
Score = 57.0 bits (136), Expect = 7e-08
Identities = 49/194 (25%), Positives = 78/194 (40%), Gaps = 24/194 (12%)
Frame = +1
Query: 301 GSFLCKNGRCIESG---SSYECKCNLGF---QESSDGK-------ICSDIDECTTNPTIC 441
G +C++G C+ G + C C GF Q D + + + + + + +C
Sbjct: 146 GQPVCESG-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVC 204
Query: 442 DRGTCINSPG---SYQCS--------CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVC 588
+ C + G + C C GF I N+ G C D +EC LC+ G C
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGF-IPNIRTGA-CQDVDECQAIPGLCQGGNC 262
Query: 589 INIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCS 768
IN GSF+C+C +G+ + Q C I + S + D + C ++ C
Sbjct: 263 INTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGICDGGE--------CTNTVSSYFCK 314
Query: 769 CPYGMESILDTGLC 810
CP G + D C
Sbjct: 315 CPPGFYTSPDGTRC 328
>sp|Q61554|FBN1_MOUSE Fibrillin-1 precursor
Length = 2871
Score = 136 bits (343), Expect = 7e-32
Identities = 83/247 (33%), Positives = 106/247 (42%), Gaps = 30/247 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNL--KSQC-DKF 300
C+GG C N + YRCEC P L AC +N+ S NL +C +
Sbjct: 1124 CRGGICHNTEGTYRCECPPGHQLSPNISACI--------DINECELSANLCPHGRCVNLI 1175
Query: 301 GSFLCK-----------------------NGRC----IESGSSYECKCNLGFQESSDGKI 399
G + C NG C S SYEC C GF D +
Sbjct: 1176 GKYQCACNPGYHPTHDRLFCVDIDECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQRS 1235
Query: 400 CSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKN 579
C+DID+C NP ICD G C N PG Y+C CYDGF C D NEC + ++C +
Sbjct: 1236 CTDIDQCEDNPNICDGGQCTNIPGEYRCLCYDGFMASE--DMKTCVDVNECDLNPNICLS 1293
Query: 580 GVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTF 759
G C N GSF C C+ GY K C +D + + + C + + C G+F
Sbjct: 1294 GTCENTKGSFICHCDMGYSGKKGKTGC------TDINECEIGAHNCGRHA-VCTNTAGSF 1346
Query: 760 KCSCPYG 780
KCSC G
Sbjct: 1347 KCSCSPG 1353
Score = 132 bits (333), Expect = 1e-30
Identities = 76/227 (33%), Positives = 104/227 (45%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ GRCI YRCEC F LD +G+ +C+K
Sbjct: 460 CQNGRCIPTPGSYRCECNKGFQLDIRGECIDV-------------------DECEKNP-- 498
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C G CI + SY C C G+Q + C DIDEC N IC+ G CIN+ GS+ C C
Sbjct: 499 -CTGGECINNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVC 557
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
GF H G C D +EC ++C NG+CIN GSFKC C G+ +S+ + C I
Sbjct: 558 NAGF--HVSSEGKNCEDMDEC-RTPNMCPNGMCINEDGSFKCICKPGFQLASDGRYCKDI 614
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ + + N + C +G+++C C G+ LD C
Sbjct: 615 NE-CETPGICMNGR--------CVNTDGSYRCECFPGLAVGLDGRWC 652
Score = 131 bits (329), Expect = 3e-30
Identities = 79/244 (32%), Positives = 108/244 (44%), Gaps = 13/244 (5%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G CINM +RCEC F + + C+ E C G
Sbjct: 1777 CENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDE------------------CQN-GPV 1817
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+N CI + SY C C G++ +S G+ C+D +EC P IC G CI++ GS+ C C
Sbjct: 1818 CLRNAECINTAGSYRCDCKPGYRLTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLC 1876
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
+ GF + C D NEC D C NG C N GSF C+CN G++ S N DCI +
Sbjct: 1877 HTGFKTNE--DQTMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGFILSHNN-DCIDV 1931
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGM-------------ESILDTGLC 810
+ + N C + C G+F+C C G E +LD G C
Sbjct: 1932 DECAT-----GNGNLCR--NGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKC 1984
Query: 811 APNS 822
AP +
Sbjct: 1985 APGT 1988
Score = 129 bits (324), Expect = 1e-29
Identities = 69/236 (29%), Positives = 105/236 (44%), Gaps = 1/236 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C N ++C C F LD + + C E +
Sbjct: 1039 CTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECR-------------------ISPD 1079
Query: 310 LCKNGRCIESGSSYECKCNLGFQES-SDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
LC G+C+ + +ECKC+ G++ K C DIDEC +P +C G C N+ G+Y+C
Sbjct: 1080 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGICHNTEGTYRCE 1139
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G + P C D NEC +LC +G C+N+ G ++C CN GY + ++ C+
Sbjct: 1140 CPPGHQLS--PNISACIDINECELSANLCPHGRCVNLIGKYQCACNPGYHPTHDRLFCVD 1197
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVD 834
I D+ S C +C +G+++CSC G + D C Q D
Sbjct: 1198 I---------DECSIMNGGCETFCTNSDGSYECSCQPGFALMPDQRSCTDIDQCED 1244
Score = 128 bits (322), Expect = 2e-29
Identities = 70/235 (29%), Positives = 110/235 (46%), Gaps = 21/235 (8%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAA-----SSFNLK---- 282
C G+CI+ + C C F ++ C E + + + SFN +
Sbjct: 1860 CSHGQCIDTVGSFYCLCHTGFKTNEDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHG 1919
Query: 283 ------------SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT 426
+C LC+NG+C+ + S++C+CN G++ + DG+ C DI+EC
Sbjct: 1920 FILSHNNDCIDVDECATGNGNLCRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVL 1979
Query: 427 NPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGS 606
+P C GTC N GSY+C C G+++ N KC D +EC E+ +C G C N GS
Sbjct: 1980 DPGKCAPGTCQNLDGSYRCICPPGYSLQN----DKCEDIDECVEEPEICALGTCSNTEGS 2035
Query: 607 FKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
FKC C G+ SS+ + C ++ S Y+ + KCS + + +C C
Sbjct: 2036 FKCLCPEGFSWSSSGRRCQDLRMSYCYAKFEG-----GKCSSPKSRNHSKQECCC 2085
Score = 127 bits (320), Expect = 3e-29
Identities = 68/218 (31%), Positives = 99/218 (45%), Gaps = 1/218 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ G C+N + Y C C +T Y P+ + N +Q K +F
Sbjct: 2413 CRNGECVNDRGSYHCIC---------------KTGYTPDITGTSCVDLNECNQAPKPCNF 2457
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+CKN + SY+C C G+ DG+ C D+DEC T C + C+N+ G + C C
Sbjct: 2458 ICKN-----TEGSYQCSCPNGYILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKC 2511
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLC-KNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
GFT H+ C D NEC+ D +LC G+C N GSF C+C G+ + C
Sbjct: 2512 PPGFTQHH----TACIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQSGASCED 2567
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ D + +C H C + G ++CSCP G
Sbjct: 2568 V----------DECEGNHRCQHGCQNIIGGYRCSCPQG 2595
Score = 123 bits (309), Expect = 6e-28
Identities = 65/169 (38%), Positives = 90/169 (53%), Gaps = 1/169 (0%)
Frame = +1
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+LC+NGRCI + SY C+CN GFQ G+ C D+DEC NP C G CIN+ GSY C
Sbjct: 458 YLCQNGRCIPTPGSYRCECNKGFQLDIRGE-CIDVDECEKNP--CTGGECINNQGSYTCH 514
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G+ + +C D +EC ++ +C NG CIN GSF C CN+G+ SS ++C
Sbjct: 515 CRAGY--QSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVSSEGKNCED 572
Query: 667 IQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSCPYGMESILDTGLC 810
+ D + + C + C +G+FKC C G + D C
Sbjct: 573 M----------DECRTPNMCPNGMCINEDGSFKCICKPGFQLASDGRYC 611
Score = 123 bits (309), Expect = 6e-28
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 1/201 (0%)
Frame = +1
Query: 211 QACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSD 390
+ C + + + + F ++C S LC +G+C + S++C+C+ GF S+
Sbjct: 1006 ELCPRGPGFATKDITNGKPFFKDINECKMIPS-LCTHGKCRNTIGSFKCRCDSGFALDSE 1064
Query: 391 GKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSL 570
+ C+DIDEC +P +C RG C+N+PG ++C C +G+ M C D +EC D L
Sbjct: 1065 ERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMM-MKNCMDIDECQRDPLL 1123
Query: 571 CKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFV 747
C+ G+C N G+++C+C G+ S N CI I + + SA + C H C +
Sbjct: 1124 CRGGICHNTEGTYRCECPPGHQLSPNISACIDINE-CELSA--------NLCPHGRCVNL 1174
Query: 748 NGTFKCSCPYGMESILDTGLC 810
G ++C+C G D C
Sbjct: 1175 IGKYQCACNPGYHPTHDRLFC 1195
Score = 122 bits (305), Expect = 2e-27
Identities = 79/279 (28%), Positives = 121/279 (43%), Gaps = 36/279 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF-GS 306
C GG+C N+ +YRC C F+ + + C E D + L C+ GS
Sbjct: 1249 CDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNEC------DLNPNICLSGTCENTKGS 1302
Query: 307 FLC--------KNGR---------------------CIESGSSYECKCNLGFQESSDGKI 399
F+C K G+ C + S++C C+ G+ DG
Sbjct: 1303 FICHCDMGYSGKKGKTGCTDINECEIGAHNCGRHAVCTNTAGSFKCSCSPGW--IGDGIK 1360
Query: 400 CSDIDECTTNPTICDR-GTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCK 576
C+D+DEC+ +C + C N+ GSY+C C DG+T G C D +ECSE+ +LC
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKDGYT----GDGFTCTDLDECSENLNLCG 1416
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF---- 744
NG C+N G ++C+C+ G+V S++ + C I + S + C F
Sbjct: 1417 NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECS--------------LPNICVFGTCH 1462
Query: 745 -VNGTFKCSCPYGMESILDTGLCAPNSQIVDVQFDIPNN 858
+ G F+C C G E G C ++ +D I N
Sbjct: 1463 NLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGN 1501
Score = 116 bits (290), Expect = 9e-26
Identities = 76/294 (25%), Positives = 113/294 (38%), Gaps = 58/294 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKK-------RTEYKPNQMNDAASSFNL-KS 285
C G C N Y C C PD++ G C R Y NQ D FN+ K
Sbjct: 1658 CGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSICYRNYYADNQTCDGELLFNMTKK 1717
Query: 286 QC----------------------DKFGSF----------------------------LC 315
C D+F + +C
Sbjct: 1718 MCCCSYNIRRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC 1777
Query: 316 KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYD 495
+NG CI S+ C+C +GF + +C DIDEC P CIN+ GSY+C C
Sbjct: 1778 ENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCLRNAECINTAGSYRCDCKP 1837
Query: 496 GFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQD 675
G+ + +C DRNEC E ++C +G CI+ GSF C C++G+ + ++ C+ I +
Sbjct: 1838 GY---RLTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNEDQTMCLDINE 1894
Query: 676 SSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
+ + C G+F C C +G + + N+ +DV
Sbjct: 1895 CERDACGNGT----------CRNTIGSFNCRCNHGF-------ILSHNNDCIDV 1931
Score = 115 bits (288), Expect = 2e-25
Identities = 65/218 (29%), Positives = 96/218 (44%), Gaps = 26/218 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQ------------------------GQACKKRTEY 237
C+ G+CIN YRCEC ++L+ G C +
Sbjct: 2137 CRHGQCINTDGSYRCECPFGYILEGNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGF 2196
Query: 238 KPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE 417
+P M ++C + LC RC+ + SYECKC +G+ D ++C D DE
Sbjct: 2197 EPGPMMTCEDI----NECAQ-NPLLCAF-RCVNTYGSYECKCPVGYVLREDRRMCKDEDE 2250
Query: 418 CTTNPTICDRGT--CINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCI 591
C C C N G+Y C C G+ P G C D NEC +C+NG C+
Sbjct: 2251 CAEGKHDCTEKQMECKNLIGTYMCICGPGY--QRRPDGEGCIDENECQTKPGICENGRCL 2308
Query: 592 NIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDN 705
N GS+ C+CN G+ AS + +C+ ++ +S V +N
Sbjct: 2309 NTLGSYTCECNDGFTASPTQDECLDNREGYCFSEVFEN 2346
Score = 115 bits (287), Expect = 2e-25
Identities = 66/215 (30%), Positives = 98/215 (45%), Gaps = 3/215 (1%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNG 324
C N YRC C + D G C +++ + + NL C NG
Sbjct: 1380 CKNTMGSYRCLCKDGYTGD--GFTC--------TDLDECSENLNL-----------CGNG 1418
Query: 325 RCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFT 504
+C+ + Y C+C++GF S+DGK C DIDEC+ P IC GTC N PG ++C C G+
Sbjct: 1419 QCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYE 1477
Query: 505 IHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSD 684
+ G C D NEC D + C +G C+N GS+ C C+ + + + C+ + +
Sbjct: 1478 LDR--SGGNCTDVNECL-DPTTCISGNCVNTPGSYTCDCSPDFELNPTRVGCVDTRSGNC 1534
Query: 685 YSAV---DDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
Y + DN + CS+ C C G
Sbjct: 1535 YLNIRPRGDNGD--TACSNEIGVGVSKASCCCSLG 1567
Score = 114 bits (284), Expect = 5e-25
Identities = 72/241 (29%), Positives = 95/241 (39%), Gaps = 50/241 (20%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQG--------------------------------Q 213
C GRC+N YRCEC P + G +
Sbjct: 623 CMNGRCVNTDGSYRCECFPGLAVGLDGRWCVDTHMRSSCYGGYRRGQCVKPLFGAVTKSE 682
Query: 214 ACKKRTEY---KPNQMNDAASSFNLKSQCDKFGSF---------------LCKNGRCIES 339
C TEY +P Q A +S ++ C +C NG C
Sbjct: 683 CCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGTDINECALDPDICPNGICENL 742
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
+Y+C CN G++ GK C DI+EC N +CD G C N+PGS+ C+C GF P
Sbjct: 743 RGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFVY--KP 800
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVD 699
C D +EC + S C NGVC N GSF C+C+ K CI + + V
Sbjct: 801 DLKTCEDIDEC--ESSPCINGVCKNSPGSFICECSPESTLDPTKTICIETIKGTCWQTVI 858
Query: 700 D 702
D
Sbjct: 859 D 859
Score = 105 bits (261), Expect = 2e-22
Identities = 71/258 (27%), Positives = 98/258 (37%), Gaps = 31/258 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN ++C C P F L G+ CK E C+ G
Sbjct: 582 CPNGMCINEDGSFKCICKPGFQLASDGRYCKDINE------------------CETPG-- 621
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCI---------- 459
+C NGRC+ + SY C+C G DG+ C D ++ RG C+
Sbjct: 622 ICMNGRCVNTDGSYRCECFPGLAVGLDGRWCVDTHMRSSCYGGYRRGQCVKPLFGAVTKS 681
Query: 460 --------------------NSPGSYQCSCYDGFTIHNMPGGPKC-YDRNECSEDKSLCK 576
+ YQ C G PG D NEC+ D +C
Sbjct: 682 ECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG------PGMTSAGTDINECALDPDICP 735
Query: 577 NGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT 756
NG+C N+ G++KC CNSGY ++C+ I + S + DN + C G+
Sbjct: 736 NGICENLRGTYKCICNSGYEVDITGKNCVDINECVLNSLLCDNGQ--------CRNTPGS 787
Query: 757 FKCSCPYGMESILDTGLC 810
F C+CP G D C
Sbjct: 788 FVCTCPKGFVYKPDLKTC 805
Score = 103 bits (256), Expect = 8e-22
Identities = 65/233 (27%), Positives = 91/233 (39%), Gaps = 21/233 (9%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMN------DAASSFNLK-------- 282
C N + Y+C C ++L + G++CK E Q N + F K
Sbjct: 2459 CKNTEGSYQCSCPNGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQH 2518
Query: 283 -------SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTIC 441
++C + G C + S+ C+C GF G C D+DEC N C
Sbjct: 2519 HTACIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHR-C 2577
Query: 442 DRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
G C N G Y+CSC G+ H +C D NEC +C C N GS+KC C
Sbjct: 2578 QHG-CQNIIGGYRCSCPQGYLQHYQ--WNQCVDENECL-SAHVCGGASCHNTLGSYKCMC 2633
Query: 622 NSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+G+ C I + A CS+ C+ G + C CP G
Sbjct: 2634 PAGFQYEQFSGGCQDINECGSSQA---------PCSYGCSNTEGGYLCGCPPG 2677
Score = 92.0 bits (227), Expect = 2e-18
Identities = 60/214 (28%), Positives = 90/214 (42%), Gaps = 18/214 (8%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQC-DKFGS 306
C G C+N Y C+C PDF L+ C T +N N + C ++ G
Sbjct: 1497 CISGNCVNTPGSYTCDCSPDFELNPTRVGCVD-TRSGNCYLNIRPRGDNGDTACSNEIGV 1555
Query: 307 FLCKNGRCIESGSSYECKCNL-----------------GFQESSDGKICSDIDECTTNPT 435
+ K C G ++ C L GF+ + I DIDEC P
Sbjct: 1556 GVSKASCCCSLGKAWGTPCELCPSVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPG 1615
Query: 436 ICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKC 615
+C G CIN+ GS+QC C G+ ++ C D NEC E +C G C N G++ C
Sbjct: 1616 LCQGGKCINTFGSFQCRCPTGYYLNE--DTRVCDDVNEC-ETPGICGPGTCYNTVGNYTC 1672
Query: 616 QCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYC 717
C Y+ + +C+ ++ S Y +++ C
Sbjct: 1673 ICPPDYMQVNGGNNCMDMRRSICYRNYYADNQTC 1706
Score = 90.9 bits (224), Expect = 4e-18
Identities = 66/256 (25%), Positives = 101/256 (39%), Gaps = 29/256 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYK-PNQMNDAASSFNLKSQCDKFGS 306
C G+C+N YRCEC FV G+AC+ E PN
Sbjct: 1415 CGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPN-------------------- 1454
Query: 307 FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+C G C + C+C +G++ G C+D++EC +PT C G C+N+PGSY C
Sbjct: 1455 -ICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYTCD 1512
Query: 487 CYDGFTIHNMPGG------PKCY--DRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
C F ++ G CY R + C N + + + C C+ G
Sbjct: 1513 CSPDFELNPTRVGCVDTRSGNCYLNIRPRGDNGDTACSNEIGVGV-SKASCCCSLGKAWG 1571
Query: 643 SNKQDCISIQDSSDYSA-------------------VDDNSKYCSKC-SHYCAFVNGTFK 762
+ + C S+ ++S+Y +D+ + C C G+F+
Sbjct: 1572 TPCELCPSV-NTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQ 1630
Query: 763 CSCPYGMESILDTGLC 810
C CP G DT +C
Sbjct: 1631 CRCPTGYYLNEDTRVC 1646
Score = 90.5 bits (223), Expect = 6e-18
Identities = 65/263 (24%), Positives = 102/263 (38%), Gaps = 22/263 (8%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKR------TEYKPNQMNDAASSFNLKS 285
E C G C N + ++C C F G+ C+ +++ + + S + K
Sbjct: 2022 EICALGTCSNTEGSFKCLCPEGFSWSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQ 2081
Query: 286 QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDG--KICS--------------DIDE 417
+C C C G + C L E + +IC D+DE
Sbjct: 2082 EC-------C----CALKGEGWGDPCELCPTEPDEAFRQICPFGSGIIVGPDDSAVDMDE 2130
Query: 418 CTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINI 597
C P +C G CIN+ GSY+C C G+ + G +C D +ECS C NG C N+
Sbjct: 2131 CK-EPDVCRHGQCINTDGSYRCECPFGYILE----GNECVDTDECSVGNP-CGNGTCKNV 2184
Query: 598 HGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPY 777
G F+C C G+ C I + + + C+ C G+++C CP
Sbjct: 2185 IGGFECTCEEGFEPGP-MMTCEDINECAQNPLL---------CAFRCVNTYGSYECKCPV 2234
Query: 778 GMESILDTGLCAPNSQIVDVQFD 846
G D +C + + + D
Sbjct: 2235 GYVLREDRRMCKDEDECAEGKHD 2257
Score = 86.7 bits (213), Expect = 8e-17
Identities = 59/225 (26%), Positives = 92/225 (40%), Gaps = 10/225 (4%)
Frame = +1
Query: 136 GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLC 315
GGRC+ RC C F G C++ +Y+ S+ + Q G
Sbjct: 157 GGRCVAPN---RCACTYGFT----GPQCER--DYRTGPCFTVVSNQMCQGQLS--GIVCT 205
Query: 316 KNGRCIESGSSYECKCNL----------GFQESSDGKICSDIDECTTNPTICDRGTCINS 465
K C G ++ C + GF + C D+DEC P +C G CIN+
Sbjct: 206 KTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGMCQGGNCINT 265
Query: 466 PGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASS 645
GS++C C G + + KC D +ECS +C G C N S+ C+C G+ S
Sbjct: 266 VGSFECKCPAGHKFNEV--SQKCEDIDECSTIPGVCDGGECTNTVSSYFCKCPPGFYTSP 323
Query: 646 NKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ C+ ++ Y+A+ + +CS+ +C C G
Sbjct: 324 DGTRCVDVRPGYCYTALAN-----GRCSNQLPQSITKMQCCCDLG 363
Score = 86.3 bits (212), Expect = 1e-16
Identities = 53/176 (30%), Positives = 70/176 (39%)
Frame = +1
Query: 142 RCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKN 321
RC+N Y C+C +VL + + CK E K C + K
Sbjct: 2220 RCVNTYGSYECKCPVGYVLREDRRMCKDEDECAEG-----------KHDCTE------KQ 2262
Query: 322 GRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGF 501
C +Y C C G+Q DG+ C D +EC T P IC+ G C+N+ GSY C C DGF
Sbjct: 2263 MECKNLIGTYMCICGPGYQRRPDGEGCIDENECQTKPGICENGRCLNTLGSYTCECNDGF 2322
Query: 502 TIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
T P +C D E G C + CQ S K +C +
Sbjct: 2323 TA--SPTQDECLDNRE----------GYCFSEVFENMCQIGSSNRNPVTKSECCCV 2366
Score = 80.5 bits (197), Expect = 6e-15
Identities = 48/166 (28%), Positives = 73/166 (43%), Gaps = 20/166 (12%)
Frame = +1
Query: 103 CSFSYYSEQC----KGGRCINMKNQYRCE-------CLPDFVLDKQGQACKKRTEYKPNQ 249
C++ + QC + G C + + C+ C G+A E P Q
Sbjct: 168 CTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQ 227
Query: 250 MNDAASSF--NLKS-------QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKIC 402
+ F N+++ +C +C+ G CI + S+ECKC G + + + C
Sbjct: 228 PHPCRRGFIPNIRTGACQDVDECQAIPG-MCQGGNCINTVGSFECKCPAGHKFNEVSQKC 286
Query: 403 SDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYD 540
DIDEC+T P +CD G C N+ SY C C GF + P G +C D
Sbjct: 287 EDIDECSTIPGVCDGGECTNTVSSYFCKCPPGF--YTSPDGTRCVD 330
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/271 (23%), Positives = 99/271 (36%), Gaps = 35/271 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG+CIN ++C C + L++ + C E C+ G
Sbjct: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNE------------------CETPG-- 1656
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE--CTTN----PTICDRGTCINSPG 471
+C G C + +Y C C + + + G C D+ C N CD N
Sbjct: 1657 ICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSICYRNYYADNQTCDGELLFNMTK 1716
Query: 472 SYQCSCYD-----------------------------GFTIHNMPGGPKCYDRNECSEDK 564
C Y+ GF I G P D +EC E
Sbjct: 1717 KMCCCSYNIRRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP--VDIDECREIP 1774
Query: 565 SLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAF 744
+C+NGVCIN+ GSF+C+C G+ + C I + N C + + C
Sbjct: 1775 GVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDEC-------QNGPVCLRNAE-CIN 1826
Query: 745 VNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
G+++C C G + TG C ++ ++
Sbjct: 1827 TAGSYRCDCKPGYR-LTSTGQCNDRNECQEI 1856
Score = 77.8 bits (190), Expect = 4e-14
Identities = 40/123 (32%), Positives = 62/123 (50%)
Frame = +1
Query: 412 DECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCI 591
D C +C G CI +PGSY+C C GF + ++ G +C D +EC +K+ C G CI
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL-DIRG--ECIDVDEC--EKNPCTGGECI 505
Query: 592 NIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
N GS+ C C +GY ++ + +C I + + +N + C +G+F C C
Sbjct: 506 NNQGSYTCHCRAGYQSTLTRTECRDIDECLQNGRICNNGR--------CINTDGSFHCVC 557
Query: 772 PYG 780
G
Sbjct: 558 NAG 560
Score = 69.7 bits (169), Expect = 1e-11
Identities = 65/286 (22%), Positives = 103/286 (36%), Gaps = 56/286 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEY-------KPNQMNDAASSFNL--- 279
C+ G+C+N ++C C + + G+ C E P + S+
Sbjct: 1942 CRNGQCVNTVGSFQCRCNEGYEVAPDGRTCVDINECVLDPGKCAPGTCQNLDGSYRCICP 2001
Query: 280 ------KSQCDKFGSF-----LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT 426
+C+ +C G C + S++C C GF SS G+ C D+
Sbjct: 2002 PGYSLQNDKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSWSSSGRRCQDLRMSYC 2061
Query: 427 NPTICDRGTCINSPGS-----YQCSCYD-----GFTIHNMPGGP---------------- 528
+ G C +SP S +C C G P P
Sbjct: 2062 YAKF-EGGKC-SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPFGSGIIV 2119
Query: 529 ----KCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAV 696
D +EC E +C++G CIN GS++C+C GY+ N +C+ + S +
Sbjct: 2120 GPDDSAVDMDECKEP-DVCRHGQCINTDGSYRCECPFGYILEGN--ECVDTDECSVGNPC 2176
Query: 697 DDNSKYCSKCSHYCAFVNGTFKCSCPYGME-----SILDTGLCAPN 819
+ + C V G F+C+C G E + D CA N
Sbjct: 2177 GNGT---------CKNVIGGFECTCEEGFEPGPMMTCEDINECAQN 2213
Score = 63.9 bits (154), Expect = 6e-10
Identities = 54/215 (25%), Positives = 82/215 (38%), Gaps = 30/215 (13%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQM-----NDAASSFNLK------- 282
G C N + CEC F LD+ G +C+ E + N + +
Sbjct: 2539 GICQNTPGSFTCECQRGFSLDQSGASCEDVDECEGNHRCQHGCQNIIGGYRCSCPQGYLQ 2598
Query: 283 ----SQC----DKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTI 438
+QC + + +C C + SY+C C GFQ C DI+EC ++
Sbjct: 2599 HYQWNQCVDENECLSAHVCGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSSQAP 2658
Query: 439 CDRGTCINSPGSYQCSCYDGF----TIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGS 606
C G C N+ G Y C C G+ H + G E + N ++
Sbjct: 2659 CSYG-CSNTEGGYLCGCPPGYFRIGQGHCLSGMGMGRGAPEPPASSEMDDNS--LSPEAC 2715
Query: 607 FKCQCNSGYV------ASSNKQDCISIQDSSDYSA 693
++C+ N GY S+N+ D IQD S+ A
Sbjct: 2716 YECKIN-GYPKRGRKRRSTNETDASDIQDGSEMEA 2749
Score = 56.6 bits (135), Expect = 9e-08
Identities = 49/194 (25%), Positives = 78/194 (40%), Gaps = 24/194 (12%)
Frame = +1
Query: 301 GSFLCKNGRCIESG---SSYECKCNLGF---QESSDGK-------ICSDIDECTTNPTIC 441
G +C++G C+ G + C C GF Q D + + + + + + +C
Sbjct: 146 GQPVCESG-CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVVSNQMCQGQLSGIVC 204
Query: 442 DRGTCINSPG---SYQCS--------CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVC 588
+ C + G + C C GF I N+ G C D +EC +C+ G C
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGF-IPNIRTGA-CQDVDECQAIPGMCQGGNC 262
Query: 589 INIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCS 768
IN GSF+C+C +G+ + Q C I + S V D + C ++ C
Sbjct: 263 INTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGVCDGGE--------CTNTVSSYFCK 314
Query: 769 CPYGMESILDTGLC 810
CP G + D C
Sbjct: 315 CPPGFYTSPDGTRC 328
>sp|O77469|FBLN1_CAEEL Fibulin-1 precursor
Length = 728
Score = 134 bits (338), Expect = 3e-31
Identities = 78/223 (34%), Positives = 106/223 (47%), Gaps = 8/223 (3%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C CIN+ Y+C+C P + + NDA +C KF
Sbjct: 399 CGSMECINLPGTYKCKCGPGY------------------EFNDAKKRCEDVDECIKFAGH 440
Query: 310 LCK-NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
+C + CI + S+ECKC GFQ +SDG+ C D++ECTT C++ C+N PGSYQC
Sbjct: 441 VCDLSAECINTIGSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQ-KCVNIPGSYQCI 499
Query: 487 CYDGFTIHNMPGGPKCYDRNECS----EDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQ 654
C GF + P G KC D +ECS LC G CIN GS+ CQC GY + +
Sbjct: 500 CDRGFALG--PDGTKCEDIDECSIWAGSGNDLCMGG-CINTKGSYLCQCPPGYKIQPDGR 556
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKC---SCP 774
C+ + D A+ + C+ C G+FKC CP
Sbjct: 557 TCVDV----DECAMGE----CAGSDKVCVNTLGSFKCHSIDCP 591
Score = 103 bits (256), Expect = 8e-22
Identities = 63/227 (27%), Positives = 104/227 (45%), Gaps = 2/227 (0%)
Frame = +1
Query: 136 GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLC 315
G C+N +RC+ ++G C E +N A ++C + +C
Sbjct: 356 GEECVNTPGSFRCQ--------QKGNLCAHGYE-----VNGATGFCEDVNECQQG---VC 399
Query: 316 KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT-NPTICD-RGTCINSPGSYQCSC 489
+ CI +Y+CKC G++ + K C D+DEC +CD CIN+ GS++C C
Sbjct: 400 GSMECINLPGTYKCKCGPGYEFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKC 459
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
GF + + G +C D NEC+ + C+ C+NI GS++C C+ G+ + C I
Sbjct: 460 KPGFQLAS--DGRRCEDVNECTTGIAACEQ-KCVNIPGSYQCICDRGFALGPDGTKCEDI 516
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
+ S ++ ++ C C G++ C CP G + D C
Sbjct: 517 DECSIWAGSGND-----LCMGGCINTKGSYLCQCPPGYKIQPDGRTC 558
Score = 82.0 bits (201), Expect = 2e-15
Identities = 50/182 (27%), Positives = 84/182 (46%), Gaps = 12/182 (6%)
Frame = +1
Query: 301 GSFLCKNGRC----IESGSSYECK---CNLGFQESSDGKICSDIDECTTNPTICDRGTCI 459
GS+ C +C +++ + EC C G+ + +C+DIDEC T C+
Sbjct: 303 GSYRCDAKKCGDGELQNPMTGECTSITCPNGYYPKNG--MCNDIDECVTGHNCGAGEECV 360
Query: 460 NSPGSYQCS-----CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCN 624
N+PGS++C C G+ ++ G C D NEC + +C + CIN+ G++KC+C
Sbjct: 361 NTPGSFRCQQKGNLCAHGYEVNGATG--FCEDVNECQQ--GVCGSMECINLPGTYKCKCG 416
Query: 625 SGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTG 804
GY + K+ C + + ++ + S C G+F+C C G + D
Sbjct: 417 PGYEFNDAKKRCEDVDECIKFAG------HVCDLSAECINTIGSFECKCKPGFQLASDGR 470
Query: 805 LC 810
C
Sbjct: 471 RC 472
Score = 51.2 bits (121), Expect = 4e-06
Identities = 54/232 (23%), Positives = 78/232 (33%), Gaps = 59/232 (25%)
Frame = +1
Query: 292 DKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRG-TCINSP 468
D+ S C++ G EC C GF + DG C D +EC T + C + C+N+
Sbjct: 157 DRCASSHCEHLCHDRGGEKVECSCRSGFDLAPDGMACVDRNECLTRQSPCTQSEDCVNTI 216
Query: 469 GSYQCS---------CYDGFTIHNMP------------------------GGP------- 528
G Y C + I N P G P
Sbjct: 217 GGYICQRRISRLVPHRHRANRIGNAPRRMRDDPYSRAGEYREASQANTEFGCPMGWLFQH 276
Query: 529 -KCYDRNECSEDKSLC-KNGVCINIHGSFKC---QCNSGYVASSNKQDCISIQDSSDYSA 693
C D +EC+ C C N GS++C +C G + + +C SI + Y
Sbjct: 277 GHCVDVDECNLGSHDCGPLYQCRNTQGSYRCDAKKCGDGELQNPMTGECTSITCPNGYYP 336
Query: 694 VDDNSKYCSKC--------SHYCAFVNGTFKCS-----CPYGMESILDTGLC 810
+ +C C G+F+C C +G E TG C
Sbjct: 337 KNGMCNDIDECVTGHNCGAGEECVNTPGSFRCQQKGNLCAHGYEVNGATGFC 388
>sp|Q75N90|FBN3_HUMAN Fibrillin-3 precursor
Length = 2809
Score = 134 bits (338), Expect = 3e-31
Identities = 75/237 (31%), Positives = 102/237 (43%), Gaps = 23/237 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPN-------QMNDAASSFNL--- 279
C+GG C N Y+C+C P L +G AC+ E + Q + +F
Sbjct: 1082 CRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCH 1141
Query: 280 --------KSQCDKFGSFLCKNG----RCIESGSSYECKCNLGFQESSDGKICSDIDECT 423
+ C +NG CI + SY C C G+ DG+ C+D+DEC
Sbjct: 1142 AGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE 1201
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
NP +CD+G C N PG ++C CYDGF P C D +EC + +C +G C N G
Sbjct: 1202 ENPRVCDQGHCTNMPGGHRCLCYDGFMA--TPDMRTCVDVDECDLNPHICLHGDCENTKG 1259
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSC 771
SF C C GY+ C SD + C SH C + G+F C C
Sbjct: 1260 SFVCHCQLGYMVRKGATGC------SDVDECEVGGHNCD--SHASCLNIPGSFSCRC 1308
Score = 132 bits (331), Expect = 2e-30
Identities = 69/232 (29%), Positives = 105/232 (45%)
Frame = +1
Query: 115 YYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCD 294
+++ C GRC+ + YRCEC + D +G+ D
Sbjct: 414 HFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECI----------------------DVD 451
Query: 295 KFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGS 474
+ S C +G C+ +Y C+C GFQ + + C D+DEC + +C G C+N+ GS
Sbjct: 452 ECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGS 511
Query: 475 YQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQ 654
+QC C GF + P G C D NEC+ ++C NGVC+N GSF C C G++ +
Sbjct: 512 FQCVCNAGFEL--SPDGKNCVDHNECA-TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGH 568
Query: 655 DCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
C+ I D + N +C G+F+C C G+ D +C
Sbjct: 569 YCMDI-DECQTPGICVNG--------HCTNTEGSFRCQCLGGLAVGTDGRVC 611
Score = 132 bits (331), Expect = 2e-30
Identities = 68/229 (29%), Positives = 104/229 (45%), Gaps = 1/229 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N + C C F LD Q + C E +
Sbjct: 997 CTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECR-------------------ISPD 1037
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSD-GKICSDIDECTTNPTICDRGTCINSPGSYQCS 486
LC G C+ + S+EC+C G++ K C D+DEC +P +C GTC N+ GSY+C
Sbjct: 1038 LCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQ 1097
Query: 487 CYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
C G + G C D +ECS LC +G C+N+ G+F+C C++G+ ++ ++Q C+
Sbjct: 1098 CPPGHEL--TAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVD 1155
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCA 813
I + + C +C G+++CSC G + D CA
Sbjct: 1156 INECRVQN---------GGCDVHCINTEGSYRCSCGQGYSLMPDGRACA 1195
Score = 127 bits (319), Expect = 4e-29
Identities = 68/214 (31%), Positives = 100/214 (46%), Gaps = 1/214 (0%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE PD + C + + + ++C F LC +G C + S+
Sbjct: 951 CEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPG-LCTHGTCRNTVGSF 1009
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
C C GF + + C+DIDEC +P +C +GTC+N+PGS++C C+ G+ M
Sbjct: 1010 HCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFML-MKN 1068
Query: 532 CYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSK 711
C D +EC+ D LC+ G C N GS+KCQC G+ ++ C +D+ S
Sbjct: 1069 CMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC---------EDIDECSL 1119
Query: 712 YCSKCSH-YCAFVNGTFKCSCPYGMESILDTGLC 810
C H C V G F+CSC G +S D C
Sbjct: 1120 SDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 125 bits (313), Expect = 2e-28
Identities = 65/195 (33%), Positives = 97/195 (49%)
Frame = +1
Query: 196 LDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGF 375
L+ G + P N ++ N + + LC NGRC+ + SSY C+CN+G+
Sbjct: 380 LNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGY 439
Query: 376 QESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECS 555
+ G+ C D+DECT++P C G C+N PG+Y C CY GF P C D +EC
Sbjct: 440 TQDVRGE-CIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGF--QATPTRQACVDVDECI 494
Query: 556 EDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHY 735
LC G C+N GSF+C CN+G+ S + ++C+ + + S C +
Sbjct: 495 VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECA-------TSTMC--VNGV 545
Query: 736 CAFVNGTFKCSCPYG 780
C +G+F C C G
Sbjct: 546 CLNEDGSFSCLCKPG 560
Score = 123 bits (309), Expect = 6e-28
Identities = 67/216 (31%), Positives = 95/216 (43%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
+ C G C N+ Y C C P FV+ G +C
Sbjct: 1854 QPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDF-------------------DECTTLV 1894
Query: 304 SFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQC 483
+C+ G C+ + S+ C C GF+ ++DGK C D +EC + C GTC N GS++C
Sbjct: 1895 GQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRC 1954
Query: 484 SCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCI 663
C GF + + C D +ECSE+ +LC G C N GSF+C C G+V S N C
Sbjct: 1955 ICPPGFQVQS----DHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCF 2010
Query: 664 SIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
+ S ++ + KCS AF +C C
Sbjct: 2011 DTRQSFCFTRFE-----AGKCSVPKAFNTTKTRCCC 2041
Score = 121 bits (303), Expect = 3e-27
Identities = 71/218 (32%), Positives = 104/218 (47%), Gaps = 4/218 (1%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYK--PNQMNDAASSFNLKSQCDKFGSFLCK 318
CIN+ YRC+C + L G AC R E + PN +C
Sbjct: 1780 CINIPGSYRCKCTRGYKLSPGG-ACVGRNECREIPN---------------------VCS 1817
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C+++ SY C C+ GFQ S+D +C DIDEC P C GTC N GSY C C+ G
Sbjct: 1818 HGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPG 1875
Query: 499 FTI-HNMPGGPKCYDRNECSE-DKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQ 672
F + HN C D +EC+ +C+ G C+N GSF C C G+ +++ ++C+
Sbjct: 1876 FVVTHN----GDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTN 1931
Query: 673 DSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
+ + C + C + G+F+C CP G +
Sbjct: 1932 ECLSLAGT------CLPGT--CQNLEGSFRCICPPGFQ 1961
Score = 119 bits (298), Expect = 1e-26
Identities = 68/233 (29%), Positives = 98/233 (42%), Gaps = 1/233 (0%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN +RC C + D C E SQ K +F
Sbjct: 2374 CAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC---------------SQVPKPCTF 2418
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
LCKN + S+ C C G+ DG+ C D+DECT+ C + C+N+ G++ C C
Sbjct: 2419 LCKNTK-----GSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC-QFLCVNTVGAFTCRC 2472
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLC-KNGVCINIHGSFKCQCNSGYVASSNKQDCIS 666
GFT H+ C+D +ECS C +G C N GSF+C+C+ G+ S+ C
Sbjct: 2473 PPGFTQHHQ----ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Query: 667 IQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQ 825
+ + +C H C G ++CSCP G C ++
Sbjct: 2529 VNECDG----------PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENE 2571
Score = 116 bits (291), Expect = 7e-26
Identities = 64/214 (29%), Positives = 92/214 (42%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C+N+ YRC C F D G C+ R E N LC
Sbjct: 1336 GDCLNVPGSYRCTCRQGFAGD--GFFCEDRDECAENVD-------------------LCD 1374
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
NG+C+ + Y C+C +GF + D + C D+DEC +C G+C N PG ++C C G
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCICNGG 1433
Query: 499 FTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDS 678
+ + GG C D NEC++ + C NGVCIN GS+ C C + + + C+ +
Sbjct: 1434 YELDR--GGGNCTDINECADPVN-CINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAG 1490
Query: 679 SDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
+ + D CS C C G
Sbjct: 1491 NCFLETHDRGDSGISCSAEIGVGVTRASCCCSLG 1524
Score = 115 bits (287), Expect = 2e-25
Identities = 79/273 (28%), Positives = 109/273 (39%), Gaps = 59/273 (21%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACK----KRTEY-------------------- 237
C G C N + +RC+CL + G+ C + T Y
Sbjct: 582 CVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSE 641
Query: 238 -----------KPNQMNDAASSFNLKSQCDK---------------FGSFLCKNGRCIES 339
+P Q+ A +S ++ C +C NG C
Sbjct: 642 CCCANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENL 701
Query: 340 GSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMP 519
SY C CNLG++ + GK C+D+DEC N +CD G C NSPGSY CSC GF H
Sbjct: 702 RGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGF--HFWQ 759
Query: 520 GGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSG--------YVASSNKQDC-ISIQ 672
C D +EC S C +GVC N+ GS+ C+C G + S K C + IQ
Sbjct: 760 DTEICKDVDECL--SSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQ 817
Query: 673 DSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSC 771
+ S + N + S S CA + + C
Sbjct: 818 E----SRCEVNLQGASLRSECCATLGAAWGSPC 846
Score = 112 bits (280), Expect = 1e-24
Identities = 66/214 (30%), Positives = 93/214 (43%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNG 324
C+N+ + C CLP +V D G C +D + + +C G
Sbjct: 1297 CLNIPGSFSCRCLPGWVGD--GFEC-----------HDLDECVSQEHRCSP-------RG 1336
Query: 325 RCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFT 504
C+ SY C C GF + DG C D DEC N +CD G C+N+PG Y+C C GF
Sbjct: 1337 DCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGF- 1393
Query: 505 IHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSD 684
C D +EC++ +LC G C N+ G F+C CN GY +C I + +D
Sbjct: 1394 -DPTEDHRACQDVDECAQG-NLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD 1451
Query: 685 YSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
+ + C G++ CSCP E
Sbjct: 1452 ---------PVNCINGVCINTPGSYLCSCPQDFE 1476
Score = 111 bits (278), Expect = 2e-24
Identities = 77/292 (26%), Positives = 114/292 (39%), Gaps = 62/292 (21%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPN-QMNDAASSFNLKS------------ 285
CIN + YRC C + L G+AC E + N ++ D N+
Sbjct: 1170 CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMA 1229
Query: 286 -----------QCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNP 432
+CD +C +G C + S+ C C LG+ CSD+DEC
Sbjct: 1230 TPDMRTCVDVDECD-LNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGG 1288
Query: 433 TICD-RGTCINSPGSYQCSCY-----DGFTIH-------------------NMPG----- 522
CD +C+N PGS+ C C DGF H N+PG
Sbjct: 1289 HNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCT 1348
Query: 523 --------GPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDS 678
G C DR+EC+E+ LC NG C+N G ++C+C G+ + + + C + +
Sbjct: 1349 CRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDEC 1408
Query: 679 SDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVD 834
+ C+ S C + G F+C C G E G C ++ D
Sbjct: 1409 A-------QGNLCAFGS--CENLPGMFRCICNGGYELDRGGGNCTDINECAD 1451
Score = 110 bits (274), Expect = 7e-24
Identities = 72/239 (30%), Positives = 97/239 (40%), Gaps = 27/239 (11%)
Frame = +1
Query: 145 CINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK-- 318
C N K + C C ++L++ G+ CK E Q N N G+F C+
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNT------VGAFTCRCP 2473
Query: 319 -------------------------NGRCIESGSSYECKCNLGFQESSDGKICSDIDECT 423
+G C + S+ C+C+ GF S G C D++EC
Sbjct: 2474 PGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD 2533
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
P C G C N G Y+CSC GFT H+ +C D NEC+ C + C N G
Sbjct: 2534 -GPHRCQHG-CQNQLGGYRCSCPQGFTQHSQ--WAQCVDENECALSPPTCGSASCRNTLG 2589
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYG 780
F+C C SG+ C QD VD+ + CS+ CA G F C CP G
Sbjct: 2590 GFRCVCPSGFDFDQALGGC---QD------VDECAGRRGPCSYSCANTPGGFLCGCPQG 2639
Score = 108 bits (271), Expect = 2e-23
Identities = 70/236 (29%), Positives = 101/236 (42%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G CIN +RCEC F + AC+ D + +S C +
Sbjct: 1732 CANGICINQIGSFRCECPAGFNYNSILLACE-----------DVDECGSRESPCQQ---- 1776
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
N CI SY CKC G++ S G C +EC P +C G C+++ GSY C C
Sbjct: 1777 ---NADCINIPGSYRCKCTRGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLC 1832
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
+ GF C D +EC D+ C NG C NI GS+ C C G+V + N DC+
Sbjct: 1833 HRGFQAS--ADQTLCMDIDEC--DRQPCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDF 1887
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
+ + + V ++ +C G+F C C G E D C ++ + +
Sbjct: 1888 DECT--TLVGQVCRF-----GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSL 1936
Score = 106 bits (264), Expect = 1e-22
Identities = 75/282 (26%), Positives = 113/282 (40%), Gaps = 55/282 (19%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQM--------NDAASSFNLK- 282
C GRC+N + ++C C F L G+ C E + M D + S K
Sbjct: 500 CHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKP 559
Query: 283 --------------SQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDEC 420
+C G +C NG C + S+ C+C G +DG++C D
Sbjct: 560 GFLLAPGGHYCMDIDECQTPG--ICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVR 617
Query: 421 TTNPTICDRGTCINS-PGSY---QCSCYD---GFTIHNMPGGPKCY-------------- 537
+T ++G+C PG+ +C C + GF G C
Sbjct: 618 STCYGAIEKGSCARPFPGTVTKSECCCANPDHGF-------GEPCQLCPAKNSAEFQALC 670
Query: 538 -----------DRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSD 684
D NEC+ D +C NGVC N+ GS++C CN GY A ++ +DC + + +
Sbjct: 671 SSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECAL 730
Query: 685 YSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLC 810
S + DN +C G++ CSCP G DT +C
Sbjct: 731 NSLLCDNG--------WCQNSPGSYSCSCPPGFHFWQDTEIC 764
Score = 98.6 bits (244), Expect = 2e-20
Identities = 54/165 (32%), Positives = 77/165 (46%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+C NG C+ + S+ C+C G+ G C D DEC+ C +GTC N G ++C+C
Sbjct: 2094 VCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP-CGQGTCTNVIGGFECAC 2152
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISI 669
DGF M C D +ECS + LC C N GS+ C C +GY + C +
Sbjct: 2153 ADGFEPGLMM---TCEDIDECSLNPLLCAFR-CHNTEGSYLCTCPAGYTLREDGAMCRDV 2208
Query: 670 QDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTG 804
+ +D + C C + GTF C CP GM + +G
Sbjct: 2209 DECAD------GQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG 2247
Score = 95.1 bits (235), Expect = 2e-19
Identities = 71/248 (28%), Positives = 98/248 (39%), Gaps = 15/248 (6%)
Frame = +1
Query: 112 SYYSEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTE------YKPNQMNDAASSF 273
S +S C G C N Y C C +++ G C + Y N+ A +
Sbjct: 1610 STHSSICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNV 1669
Query: 274 NLKSQCDKFGSFLCKNGRC----IESGSSYECKCNL---GFQESSDGKICSDIDECTTNP 432
K C + N C Y+ C GF DIDEC P
Sbjct: 1670 TRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIP 1729
Query: 433 TICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCK-NGVCINIHGSF 609
IC G CIN GS++C C GF +++ C D +EC +S C+ N CINI GS+
Sbjct: 1730 AICANGICINQIGSFRCECPAGFNYNSILLA--CEDVDECGSRESPCQQNADCINIPGSY 1787
Query: 610 KCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSCPYGME 786
+C+C GY S C+ + + V CSH C G++ C C G +
Sbjct: 1788 RCKCTRGYKLSPGGA-CVGRNECREIPNV---------CSHGDCMDTEGSYMCLCHRGFQ 1837
Query: 787 SILDTGLC 810
+ D LC
Sbjct: 1838 ASADQTLC 1845
Score = 95.1 bits (235), Expect = 2e-19
Identities = 64/232 (27%), Positives = 83/232 (35%), Gaps = 43/232 (18%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C+N +RCEC + LD G C E
Sbjct: 2095 CTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHP------------------- 2135
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
C G C +EC C GF E C DIDEC+ NP +C C N+ GSY C+C
Sbjct: 2136 -CGQGTCTNVIGGFECACADGF-EPGLMMTCEDIDECSLNPLLC-AFRCHNTEGSYLCTC 2192
Query: 490 YDGFTIHN------------------------------------------MPG-GPKCYD 540
G+T+ +PG G C D
Sbjct: 2193 PAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTD 2252
Query: 541 RNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAV 696
NEC LC NG C+N GSF+C C+ G+ S +C I+ ++ V
Sbjct: 2253 DNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 90.1 bits (222), Expect = 7e-18
Identities = 58/205 (28%), Positives = 77/205 (37%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C N +RCEC F L G C+ E CD G C+
Sbjct: 2500 GHCHNTPGSFRCECHQGFTLVSSGHGCEDVNE------------------CD--GPHRCQ 2539
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C Y C C GF + S C D +EC +P C +C N+ G ++C C G
Sbjct: 2540 HG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSG 2598
Query: 499 FTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDS 678
F GG C D +EC+ + C C N G F C C GY + + S
Sbjct: 2599 FDFDQALGG--CQDVDECAGRRGPCSYS-CANTPGGFLCGCPQGYFRAGQGHCVSGLGFS 2655
Query: 679 SDYSAVDDNSKYCSKCSHYCAFVNG 753
D + S + Y +NG
Sbjct: 2656 PGPQDTPDKEELLSSEACYECKING 2680
Score = 89.7 bits (221), Expect = 1e-17
Identities = 67/251 (26%), Positives = 93/251 (37%), Gaps = 22/251 (8%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
E C G C N++ YRC C + G+ C E N
Sbjct: 691 EVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALN------------------- 731
Query: 304 SFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQC 483
S LC NG C S SY C C GF D +IC D+DEC ++P C G C N GSY C
Sbjct: 732 SLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--CVSGVCRNLAGSYTC 789
Query: 484 SCYDGFTIHNMPGGPKCYD-------------RNECSEDKSLCKNGVCINIHGSF----- 609
C G + P G C D R E + + ++ C + ++
Sbjct: 790 KCGPGSRLD--PSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCE 847
Query: 610 KCQ----CNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPY 777
+C+ C G+ A C + + + V N + C G+F+C CP
Sbjct: 848 RCEIDPACARGF-ARMTGVTCDDVNECESFPGVCPNGR--------CVNTAGSFRCECPE 898
Query: 778 GMESILDTGLC 810
G+ LC
Sbjct: 899 GLMLDASGRLC 909
Score = 88.6 bits (218), Expect = 2e-17
Identities = 67/264 (25%), Positives = 89/264 (33%), Gaps = 51/264 (19%)
Frame = +1
Query: 142 RCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF---- 309
RC N + Y C C + L + G C+ E Q + A K+ F
Sbjct: 2180 RCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPG 2239
Query: 310 ----------------------LCKNGRCIESGSSYECKCNLGFQESSDGKICSDI---- 411
LC NGRC+ + S+ C C+ GFQ S C DI
Sbjct: 2240 MRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGP 2299
Query: 412 ----------------DECTTNPTICDRGTCINSPGSYQC-----SCYDGFTIHNMPGGP 528
E T C G P C S Y H
Sbjct: 2300 CFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTA 2359
Query: 529 KCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNS 708
+ D +EC LC +G CIN GSF+C C +GY + C+ +D+ S
Sbjct: 2360 EGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLD---------MDECS 2410
Query: 709 KYCSKCSHYCAFVNGTFKCSCPYG 780
+ C+ C G+F CSCP G
Sbjct: 2411 QVPKPCTFLCKNTKGSFLCSCPRG 2434
Score = 83.2 bits (204), Expect = 9e-16
Identities = 76/275 (27%), Positives = 114/275 (41%), Gaps = 39/275 (14%)
Frame = +1
Query: 172 CECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCKNGRCIESGSSY 351
CE P + C ++PN++ + +C + LC+ G C+ + S+
Sbjct: 1531 CELCPMANTTEYRTLCPGGEGFQPNRITVILEDID---ECQELPG-LCQGGDCVNTFGSF 1586
Query: 352 ECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPK 531
+C+C G+ S +IC DIDEC+T+ +IC GTC N+ G+Y C C + N GG
Sbjct: 1587 QCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCPAEYLQVN--GGNN 1644
Query: 532 CYDRNECSEDKSLC---KNGVCIN---IHGSFKCQCNSGYVASSNKQDCISIQD--SSDY 687
C D KS+C NG C N + + K C S + + + C + S DY
Sbjct: 1645 CMDMR-----KSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDY 1699
Query: 688 SAVDDNS----------------KYCSKCSHYCA---FVN--GTFKCSCPYGM--ESIL- 795
+ N C + CA +N G+F+C CP G SIL
Sbjct: 1700 QILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILL 1759
Query: 796 ---DTGLC----APNSQIVDVQFDIPNNIRARVKR 879
D C +P Q D +IP + R + R
Sbjct: 1760 ACEDVDECGSRESPCQQNADC-INIPGSYRCKCTR 1793
Score = 81.6 bits (200), Expect = 3e-15
Identities = 63/256 (24%), Positives = 97/256 (37%), Gaps = 29/256 (11%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C+N YRCEC F + +AC+ E
Sbjct: 1373 CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGN-------------------- 1412
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
LC G C + C CN G++ G C+DI+EC +P C G CIN+PGSY CSC
Sbjct: 1413 LCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECA-DPVNCINGVCINTPGSYLCSC 1471
Query: 490 YDGFTIHNMPGGPKCYD---------RNECSEDKSLCKNGVCINIHGSFKCQCNSGYVAS 642
F ++ P G C D ++ + C + + + + C C+ G A
Sbjct: 1472 PQDFELN--PSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRA-SCCCSLGR-AW 1527
Query: 643 SNKQDCISIQDSSDYSA-------------------VDDNSKYCSKC-SHYCAFVNGTFK 762
N + + ++++Y +D+ + C C G+F+
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQ 1587
Query: 763 CSCPYGMESILDTGLC 810
C CP G T +C
Sbjct: 1588 CECPPGYHLSEHTRIC 1603
Score = 79.0 bits (193), Expect = 2e-14
Identities = 66/251 (26%), Positives = 89/251 (35%), Gaps = 32/251 (12%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G C N++ +RC C P F + +PN
Sbjct: 1940 CLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEEPN--------------------- 1978
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDE--CTTN------------PTICDR 447
LC G C S S++C C GF S +G C D + C T T R
Sbjct: 1979 LCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTR 2038
Query: 448 GTCINSPG----------------SYQCSCYDGFTIHNMPGGP--KCYDRNECSEDKSLC 573
C PG ++Q C G H GP D NEC+E+ +C
Sbjct: 2039 CCCSKRPGEGWGDPCELCPQEGSAAFQELCPFG---HGAVPGPDDSREDVNECAENPGVC 2095
Query: 574 KNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNG 753
NGVC+N GSF+C+C GY +C+ + S + C V G
Sbjct: 2096 TNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT---------CTNVIG 2146
Query: 754 TFKCSCPYGME 786
F+C+C G E
Sbjct: 2147 GFECACADGFE 2157
Score = 77.4 bits (189), Expect = 5e-14
Identities = 71/300 (23%), Positives = 112/300 (37%), Gaps = 68/300 (22%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQ----------MNDAASSFNL 279
C+GG C+NM + C C L AC+ +Y+ D A +
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACE---DYRAGACFSVLFGGRCAGDLAGHYTR 314
Query: 280 KSQCDKFGSFLCKNGRCIESG-----------SSYECKCN----------------LGFQ 378
+ C C GRC +G + ++ C LGF
Sbjct: 315 RQCC-------CDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFG 367
Query: 379 ES----------------------SDGKICSDIDECTTNPTI---------CDRGTCINS 465
+ S G S+I T N TI C G C+ +
Sbjct: 368 SNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPT 427
Query: 466 PGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVASS 645
P SY+C C G+T ++ G +C D +EC+ S C +G C+NI G++ C+C G+ A+
Sbjct: 428 PSSYRCECNVGYT-QDVRG--ECIDVDECT--SSPCHHGDCVNIPGTYHCRCYPGFQATP 482
Query: 646 NKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAPNSQ 825
+Q C+ + D V + +C + G+F+C C G E D C +++
Sbjct: 483 TRQACVDV----DECIVSGGLCHLGRCVN----TEGSFQCVCNAGFELSPDGKNCVDHNE 534
Score = 77.4 bits (189), Expect = 5e-14
Identities = 65/275 (23%), Positives = 106/275 (38%), Gaps = 39/275 (14%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+GG C+N ++CEC P + L + + C+ E + S
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTH-------------------SS 1614
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDR---GTCIN------ 462
+C G C + +Y C C + + + G C D+ ++C R GTC N
Sbjct: 1615 ICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDM-----RKSVCFRHYNGTCQNELAFNV 1669
Query: 463 --------------------------SPGSYQCSCYD---GFTIHNMPGGPKCYDRNECS 555
SP YQ C + GF G P D +EC
Sbjct: 1670 TRKMCCCSYNIGQAWNRPCEACPTPISP-DYQILCGNQAPGFLTDIHTGKP--LDIDECG 1726
Query: 556 EDKSLCKNGVCINIHGSFKCQCNSGYVASSNKQDCISIQD-SSDYSAVDDNSKYCSKCSH 732
E ++C NG+CIN GSF+C+C +G+ +S C + + S S N+
Sbjct: 1727 EIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNAD------- 1779
Query: 733 YCAFVNGTFKCSCPYGMESILDTGLCAPNSQIVDV 837
C + G+++C C G + + G C ++ ++
Sbjct: 1780 -CINIPGSYRCKCTRGYK-LSPGGACVGRNECREI 1812
Score = 65.1 bits (157), Expect = 3e-10
Identities = 60/266 (22%), Positives = 96/266 (36%), Gaps = 46/266 (17%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRT------EYKPNQMNDAASSFNLK 282
S C G C N+ Y C+C P LD G C T + + ++ +L+
Sbjct: 772 SSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 283 SQCDKFGSFLCKNGRCIESGSSYECK----CNLGFQESSDGKICSDIDECTTNPTICDRG 450
S+C C C+ C GF + G C D++EC + P +C G
Sbjct: 832 SEC-------CATLGAAWGSPCERCEIDPACARGFARMT-GVTCDDVNECESFPGVCPNG 883
Query: 451 TCINSPGSYQCSCYDGFTIHNMPGGPKC-----------YDRNECSEDKSLCKNGVCINI 597
C+N+ GS++C C +G + G C +D +EC + +
Sbjct: 884 RCVNTAGSFRCECPEGLMLD--ASGRLCVDVRLEPCFLRWDEDECG-----------VTL 930
Query: 598 HGSFK---CQCNSGYVASSNKQDCISIQD--------------SSD-------YSAVDDN 705
G ++ C C+ G V + C + S D Y V++
Sbjct: 931 PGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNEC 990
Query: 706 SKYCSKCSH-YCAFVNGTFKCSCPYG 780
+ C+H C G+F C+C G
Sbjct: 991 KVFPGLCTHGTCRNTVGSFHCACAGG 1016
Score = 51.6 bits (122), Expect = 3e-06
Identities = 46/173 (26%), Positives = 65/173 (37%), Gaps = 13/173 (7%)
Frame = +1
Query: 136 GGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKP--NQMNDAASSFNLKSQ-CDKFGS 306
GGRCI RC C+ F+ G C++ P Q+ L C K
Sbjct: 158 GGRCIGPN---RCACVYGFM----GPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKA-- 208
Query: 307 FLCKNGRCIESGSSYECKCNL----------GFQESSDGKICSDIDECTTNPTICDRGTC 456
LC C G ++ C L GF + C D+DEC P +C G+C
Sbjct: 209 -LC----CATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSC 263
Query: 457 INSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKC 615
+N GS+ C C P G + D + ED + G C ++ +C
Sbjct: 264 VNMVGSFHCRC---------PVGHRLSDSSAACED---YRAGACFSVLFGGRC 304
>sp|Q8CG18|LTB1S_MOUSE Latent transforming growth factor beta binding protein, isoform 1S
precursor (LTBP-1) (Transforming growth factor beta-1
binding protein 1) (TGF-beta1-BP-1)
Length = 1389
Score = 131 bits (329), Expect = 3e-30
Identities = 72/248 (29%), Positives = 112/248 (45%), Gaps = 21/248 (8%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCEC------LPDFVLDKQGQACKKRTEYKPNQMNDAASSFNL---- 279
C G C N++ Y C C PD + C++ Q + SF
Sbjct: 717 CTNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDIDECQQGNLCMNGQCRNTDGSFRCTCGQ 776
Query: 280 -------KSQCDKFGS----FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT 426
K QC+ LC +G+C + S++C CN G++ S G C DI+EC
Sbjct: 777 GYQLSAAKDQCEDIDECEHHHLCSHGQCRNTEGSFQCVCNQGYRASVLGDHCEDINECLE 836
Query: 427 NPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGS 606
+ ++C G CIN+ GSY C+C DGF +++ G C D NEC++ +G C+N GS
Sbjct: 837 DSSVCQGGDCINTAGSYDCTCPDGFQLNDNKG---CQDINECAQPGLCGSHGECLNTQGS 893
Query: 607 FKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
F C C G+ S++ + C I + + + D + +C G+F+C C G +
Sbjct: 894 FHCVCEQGFSISADGRTCEDIDECVNNTVCDSHG--------FCDNTAGSFRCLCYQGFQ 945
Query: 787 SILDTGLC 810
+ D C
Sbjct: 946 APQDGQGC 953
Score = 119 bits (298), Expect = 1e-26
Identities = 75/270 (27%), Positives = 114/270 (42%), Gaps = 31/270 (11%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCE-CLPDFVLDKQGQA-----CKKRTEYKPNQMNDAASSFNLKS 285
+ C+ GRCIN +RCE C + + ++G C K + Q + S+
Sbjct: 634 DMCRDGRCINTAGAFRCEYCDSGYRMSRRGYCEDIDECLKPSTCPEEQCVNTPGSYQCVP 693
Query: 286 QCDKFGSF--------------LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECT 423
+ F + +C NG C SY C C+ G+ + D + C DIDEC
Sbjct: 694 CTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDIDECQ 753
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
+C G C N+ GS++C+C G+ + +C D +EC E LC +G C N G
Sbjct: 754 QG-NLCMNGQCRNTDGSFRCTCGQGYQL--SAAKDQCEDIDEC-EHHHLCSHGQCRNTEG 809
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGM 783
SF+C CN GY AS C I + + S+V C G++ C+CP G
Sbjct: 810 SFQCVCNQGYRASVLGDHCEDINECLEDSSVCQGGD--------CINTAGSYDCTCPDGF 861
Query: 784 E-----------SILDTGLCAPNSQIVDVQ 840
+ GLC + + ++ Q
Sbjct: 862 QLNDNKGCQDINECAQPGLCGSHGECLNTQ 891
Score = 115 bits (288), Expect = 2e-25
Identities = 75/240 (31%), Positives = 108/240 (45%), Gaps = 23/240 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTE-YKPNQMND-----AASSF------ 273
C GRC N + + C C F+ ++G C E +P+ D A +F
Sbjct: 595 CSQGRCENTEGSFLCVCPAGFMASEEGTNCIDVDECLRPDMCRDGRCINTAGAFRCEYCD 654
Query: 274 -----NLKSQCDKFGSFL----CKNGRCIESGSSYEC-KCNLGFQESSDGKICSDIDECT 423
+ + C+ L C +C+ + SY+C C GF+ +G+ C D+DEC
Sbjct: 655 SGYRMSRRGYCEDIDECLKPSTCPEEQCVNTPGSYQCVPCTEGFR-GWNGQ-CLDVDEC- 711
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
P +C G+C N GSY CSC+ G++ P C D +EC + +LC NG C N G
Sbjct: 712 LQPKVCTNGSCTNLEGSYMCSCHRGYS--PTPDHRHCQDIDECQQG-NLCMNGQCRNTDG 768
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSCPYG 780
SF+C C GY S+ K C I D ++ CSH C G+F+C C G
Sbjct: 769 SFRCTCGQGYQLSAAKDQCEDI----------DECEHHHLCSHGQCRNTEGSFQCVCNQG 818
Score = 111 bits (278), Expect = 2e-24
Identities = 75/252 (29%), Positives = 116/252 (46%), Gaps = 33/252 (13%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQ--CDKF- 300
C G CIN+ +Y C C + +Q + C +++ A +L SQ C+
Sbjct: 553 CGAGHCINLPVRYTCICYEGYKFSEQLRKCV--------DIDECAQVRHLCSQGRCENTE 604
Query: 301 GSFL---------------------------CKNGRCIESGSSYECK-CNLGFQESSDGK 396
GSFL C++GRCI + ++ C+ C+ G++ S G
Sbjct: 605 GSFLCVCPAGFMASEEGTNCIDVDECLRPDMCRDGRCINTAGAFRCEYCDSGYRMSRRG- 663
Query: 397 ICSDIDECTTNPTICDRGTCINSPGSYQC-SCYDGFTIHNMPGGPKCYDRNECSEDKSLC 573
C DIDEC P+ C C+N+PGSYQC C +GF N +C D +EC + K +C
Sbjct: 664 YCEDIDEC-LKPSTCPEEQCVNTPGSYQCVPCTEGFRGWN----GQCLDVDECLQPK-VC 717
Query: 574 KNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVN 750
NG C N+ GS+ C C+ GY + + + C I D + + C + C +
Sbjct: 718 TNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDI----------DECQQGNLCMNGQCRNTD 767
Query: 751 GTFKCSCPYGME 786
G+F+C+C G +
Sbjct: 768 GSFRCTCGQGYQ 779
Score = 109 bits (272), Expect = 1e-23
Identities = 62/169 (36%), Positives = 81/169 (47%), Gaps = 2/169 (1%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF 300
S C+GG CIN Y C C F Q+ND ++ ++C +
Sbjct: 838 SSVCQGGDCINTAGSYDCTCPDGF------------------QLNDNKGCQDI-NECAQP 878
Query: 301 GSFLC-KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICD-RGTCINSPGS 474
G LC +G C+ + S+ C C GF S+DG+ C DIDEC N T+CD G C N+ GS
Sbjct: 879 G--LCGSHGECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNN-TVCDSHGFCDNTAGS 935
Query: 475 YQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
++C CY GF G C D NEC +C C N+ GSF C C
Sbjct: 936 FRCLCYQGFQAPQ--DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 982
Score = 87.8 bits (216), Expect = 4e-17
Identities = 38/91 (41%), Positives = 53/91 (58%)
Frame = +1
Query: 403 SDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNG 582
++I+ECT NP IC G CIN P Y C CY+G+ KC D +EC++ + LC G
Sbjct: 541 TEINECTVNPDICGAGHCINLPVRYTCICYEGYKFSEQL--RKCVDIDECAQVRHLCSQG 598
Query: 583 VCINIHGSFKCQCNSGYVASSNKQDCISIQD 675
C N GSF C C +G++AS +CI + +
Sbjct: 599 RCENTEGSFLCVCPAGFMASEEGTNCIDVDE 629
Score = 86.3 bits (212), Expect = 1e-16
Identities = 56/198 (28%), Positives = 81/198 (40%), Gaps = 31/198 (15%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+C G CI Y C C G++ S + C DIDEC +C +G C N+ GS+ C C
Sbjct: 552 ICGAGHCINLPVRYTCICYEGYKFSEQLRKCVDIDECAQVRHLCSQGRCENTEGSFLCVC 611
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQ-CNSGYVAS-----SNK 651
GF G C D +EC +C++G CIN G+F+C+ C+SGY S +
Sbjct: 612 PAGFMASE--EGTNCIDVDECLR-PDMCRDGRCINTAGAFRCEYCDSGYRMSRRGYCEDI 668
Query: 652 QDCISIQDSSDYSAVDDNSKY-CSKCSH------------------------YCAFVNGT 756
+C+ + V+ Y C C+ C + G+
Sbjct: 669 DECLKPSTCPEEQCVNTPGSYQCVPCTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGS 728
Query: 757 FKCSCPYGMESILDTGLC 810
+ CSC G D C
Sbjct: 729 YMCSCHRGYSPTPDHRHC 746
Score = 69.7 bits (169), Expect = 1e-11
Identities = 34/91 (37%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +1
Query: 439 CDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSE---DKSLCKNGVCINIHGSF 609
C+ G C+ Y C C+DG+ H C D NECSE SLCKN CIN GS+
Sbjct: 1299 CENGRCVRVHEGYTCDCFDGY--HLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSY 1356
Query: 610 KCQCNSGYVASSNKQDCISIQDSSDYSAVDD 702
KC C GY+ S C + + + D
Sbjct: 1357 KCLCLPGYIPSDKPNYCTPLNSALNLDKESD 1387
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/182 (26%), Positives = 70/182 (38%), Gaps = 18/182 (9%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C+N + + C C F + G+ C+ E N + D+
Sbjct: 885 GECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNNTVCDS------------------- 925
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C + S+ C C GFQ DG+ C D++EC +C C N GS+ C C D
Sbjct: 926 HGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADE 985
Query: 499 FTIHNMPGGPKCYDR---------------NEC---SEDKSLCKNGVCINIHGSFKCQCN 624
++ P +C R EC D SLC N + N+ +C C
Sbjct: 986 NQEYS-PMTGQCRSRVTEDSGVDRQpreEKKECYYNLNDASLCDNVLAPNVTKQ-ECCCT 1043
Query: 625 SG 630
SG
Sbjct: 1044 SG 1045
Score = 67.8 bits (164), Expect = 4e-11
Identities = 58/234 (24%), Positives = 96/234 (41%), Gaps = 27/234 (11%)
Frame = +1
Query: 154 MKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDK-FGSFLCKNGRC 330
M Q R D +D+Q + KK Y +NDA S CD + K C
Sbjct: 992 MTGQCRSRVTEDSGVDRQpreEKKECYYN---LNDA-------SLCDNVLAPNVTKQECC 1041
Query: 331 IESGSSYECKCNL------GFQESSD-------------------GKICSDIDECTT-NP 432
SG+ + C + G E ++ G+ D DEC
Sbjct: 1042 CTSGAGWGDNCEIFPCPVQGTAEFTEMCPRGKGLVPAGESSYDTGGENYKDADECLLFGE 1101
Query: 433 TICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFK 612
IC G C+N+ Y+C C G + P +C+D +EC +D + C +G C+N GS+
Sbjct: 1102 EICKNGYCLNTQPGYECYCKQG--TYYDPVKLQCFDMDEC-QDPNSCIDGQCVNTEGSYN 1158
Query: 613 CQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCP 774
C C V ++++ C+ +S++ +++ Y C + ++ + CS P
Sbjct: 1159 CFCTHPMVLDASEKRCVQPTESNE--QIEETDVYQDLCWEH---LSEEYVCSRP 1207
Score = 57.8 bits (138), Expect = 4e-08
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = +1
Query: 313 CKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECT---TNPTICDRGTCINSPGSYQC 483
C+NGRC+ Y C C G+ C D++EC+ ++C CIN+ GSY+C
Sbjct: 1299 CENGRCVRVHEGYTCDCFDGYHLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSYKC 1358
Query: 484 SCYDGFTIHNMP 519
C G+ + P
Sbjct: 1359 LCLPGYIPSDKP 1370
Score = 55.5 bits (132), Expect = 2e-07
Identities = 49/239 (20%), Positives = 79/239 (33%), Gaps = 10/239 (4%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C+N + Y C C VLD + C + TE N+ + + +
Sbjct: 1145 CIDGQCVNTEGSYNCFCTHPMVLDASEKRCVQPTE--SNEQIEETDVYQDLCWEHLSEEY 1202
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKIC--SDIDE--------CTTNPTICDRGTCI 459
+C + + EC C G +C D D+ T R +
Sbjct: 1203 VCSRPLVGKQTTYTECCCLYGEAWGMQCALCPMKDSDDYAQLCNIPVTGRRRPYGRDALV 1262
Query: 460 NSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVA 639
+ Y F + EC C+NG C+ +H + C C GY
Sbjct: 1263 DFSEQYGPETDPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVHEGYTCDCFDGYHL 1321
Query: 640 SSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAP 816
K C+ + + S+ +++ C C G++KC C G C P
Sbjct: 1322 DMAKMTCVDVNECSE---LNNRMSLCKNAK--CINTEGSYKCLCLPGYIPSDKPNYCTP 1375
Score = 50.8 bits (120), Expect = 5e-06
Identities = 26/95 (27%), Positives = 42/95 (44%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ GRC+ + Y C+C + LD C E +++N+ S
Sbjct: 1299 CENGRCVRVHEGYTCDCFDGYHLDMAKMTCVDVNEC--SELNNRMS-------------- 1342
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDID 414
LCKN +CI + SY+C C G+ S C+ ++
Sbjct: 1343 LCKNAKCINTEGSYKCLCLPGYIPSDKPNYCTPLN 1377
Score = 44.7 bits (104), Expect = 4e-04
Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 3/174 (1%)
Frame = +1
Query: 271 FNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRG 450
FN +C K S+ G + +C G++ ++ C DI+EC +C G
Sbjct: 260 FNKCQKCPKKQSY---------HGYTQMMECLQGYKRVNN-TFCQDINECQLQG-VCPNG 308
Query: 451 TCINSPGSYQCSCYDGFTIHNMPGGPKCY-DRNECSEDKSLCKNGVCINIHGSFKCQCNS 627
C+N+ GSY+CSC GF P C D SE+K C V H C
Sbjct: 309 ECLNTMGSYRCSCKMGFGPD--PTFSSCVPDPPVISEEKGPCYRLVSPGRH------CMH 360
Query: 628 GYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT--FKCSCPYGM 783
KQ C S +C KC + GT FK CP GM
Sbjct: 361 PLSVHLTKQICCC-------SVGKAWGPHCEKCP-----LPGTAAFKEICPGGM 402
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/80 (31%), Positives = 36/80 (45%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
E CK G C+N + Y C C KQG T Y P ++ F++ +C
Sbjct: 1102 EICKNGYCLNTQPGYECYC-------KQG------TYYDPVKL----QCFDM-DECQDPN 1143
Query: 304 SFLCKNGRCIESGSSYECKC 363
S C +G+C+ + SY C C
Sbjct: 1144 S--CIDGQCVNTEGSYNCFC 1161
>sp|Q8CG19|LTB1L_MOUSE Latent transforming growth factor beta binding protein, isoform 1L
precursor (LTBP-1) (Transforming growth factor beta-1
binding protein 1) (TGF-beta1-BP-1)
Length = 1713
Score = 131 bits (329), Expect = 3e-30
Identities = 72/248 (29%), Positives = 112/248 (45%), Gaps = 21/248 (8%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCEC------LPDFVLDKQGQACKKRTEYKPNQMNDAASSFNL---- 279
C G C N++ Y C C PD + C++ Q + SF
Sbjct: 1041 CTNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDIDECQQGNLCMNGQCRNTDGSFRCTCGQ 1100
Query: 280 -------KSQCDKFGS----FLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTT 426
K QC+ LC +G+C + S++C CN G++ S G C DI+EC
Sbjct: 1101 GYQLSAAKDQCEDIDECEHHHLCSHGQCRNTEGSFQCVCNQGYRASVLGDHCEDINECLE 1160
Query: 427 NPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGS 606
+ ++C G CIN+ GSY C+C DGF +++ G C D NEC++ +G C+N GS
Sbjct: 1161 DSSVCQGGDCINTAGSYDCTCPDGFQLNDNKG---CQDINECAQPGLCGSHGECLNTQGS 1217
Query: 607 FKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGME 786
F C C G+ S++ + C I + + + D + +C G+F+C C G +
Sbjct: 1218 FHCVCEQGFSISADGRTCEDIDECVNNTVCDSHG--------FCDNTAGSFRCLCYQGFQ 1269
Query: 787 SILDTGLC 810
+ D C
Sbjct: 1270 APQDGQGC 1277
Score = 119 bits (298), Expect = 1e-26
Identities = 75/270 (27%), Positives = 114/270 (42%), Gaps = 31/270 (11%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCE-CLPDFVLDKQGQA-----CKKRTEYKPNQMNDAASSFNLKS 285
+ C+ GRCIN +RCE C + + ++G C K + Q + S+
Sbjct: 958 DMCRDGRCINTAGAFRCEYCDSGYRMSRRGYCEDIDECLKPSTCPEEQCVNTPGSYQCVP 1017
Query: 286 QCDKFGSF--------------LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECT 423
+ F + +C NG C SY C C+ G+ + D + C DIDEC
Sbjct: 1018 CTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDIDECQ 1077
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
+C G C N+ GS++C+C G+ + +C D +EC E LC +G C N G
Sbjct: 1078 QG-NLCMNGQCRNTDGSFRCTCGQGYQL--SAAKDQCEDIDEC-EHHHLCSHGQCRNTEG 1133
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGM 783
SF+C CN GY AS C I + + S+V C G++ C+CP G
Sbjct: 1134 SFQCVCNQGYRASVLGDHCEDINECLEDSSVCQGGD--------CINTAGSYDCTCPDGF 1185
Query: 784 E-----------SILDTGLCAPNSQIVDVQ 840
+ GLC + + ++ Q
Sbjct: 1186 QLNDNKGCQDINECAQPGLCGSHGECLNTQ 1215
Score = 115 bits (288), Expect = 2e-25
Identities = 75/240 (31%), Positives = 108/240 (45%), Gaps = 23/240 (9%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTE-YKPNQMND-----AASSF------ 273
C GRC N + + C C F+ ++G C E +P+ D A +F
Sbjct: 919 CSQGRCENTEGSFLCVCPAGFMASEEGTNCIDVDECLRPDMCRDGRCINTAGAFRCEYCD 978
Query: 274 -----NLKSQCDKFGSFL----CKNGRCIESGSSYEC-KCNLGFQESSDGKICSDIDECT 423
+ + C+ L C +C+ + SY+C C GF+ +G+ C D+DEC
Sbjct: 979 SGYRMSRRGYCEDIDECLKPSTCPEEQCVNTPGSYQCVPCTEGFR-GWNGQ-CLDVDEC- 1035
Query: 424 TNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHG 603
P +C G+C N GSY CSC+ G++ P C D +EC + +LC NG C N G
Sbjct: 1036 LQPKVCTNGSCTNLEGSYMCSCHRGYS--PTPDHRHCQDIDECQQG-NLCMNGQCRNTDG 1092
Query: 604 SFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVNGTFKCSCPYG 780
SF+C C GY S+ K C I D ++ CSH C G+F+C C G
Sbjct: 1093 SFRCTCGQGYQLSAAKDQCEDI----------DECEHHHLCSHGQCRNTEGSFQCVCNQG 1142
Score = 111 bits (278), Expect = 2e-24
Identities = 75/252 (29%), Positives = 116/252 (46%), Gaps = 33/252 (13%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQ--CDKF- 300
C G CIN+ +Y C C + +Q + C +++ A +L SQ C+
Sbjct: 877 CGAGHCINLPVRYTCICYEGYKFSEQLRKCV--------DIDECAQVRHLCSQGRCENTE 928
Query: 301 GSFL---------------------------CKNGRCIESGSSYECK-CNLGFQESSDGK 396
GSFL C++GRCI + ++ C+ C+ G++ S G
Sbjct: 929 GSFLCVCPAGFMASEEGTNCIDVDECLRPDMCRDGRCINTAGAFRCEYCDSGYRMSRRG- 987
Query: 397 ICSDIDECTTNPTICDRGTCINSPGSYQC-SCYDGFTIHNMPGGPKCYDRNECSEDKSLC 573
C DIDEC P+ C C+N+PGSYQC C +GF N +C D +EC + K +C
Sbjct: 988 YCEDIDEC-LKPSTCPEEQCVNTPGSYQCVPCTEGFRGWN----GQCLDVDECLQPK-VC 1041
Query: 574 KNGVCINIHGSFKCQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSH-YCAFVN 750
NG C N+ GS+ C C+ GY + + + C I D + + C + C +
Sbjct: 1042 TNGSCTNLEGSYMCSCHRGYSPTPDHRHCQDI----------DECQQGNLCMNGQCRNTD 1091
Query: 751 GTFKCSCPYGME 786
G+F+C+C G +
Sbjct: 1092 GSFRCTCGQGYQ 1103
Score = 109 bits (272), Expect = 1e-23
Identities = 62/169 (36%), Positives = 81/169 (47%), Gaps = 2/169 (1%)
Frame = +1
Query: 121 SEQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKF 300
S C+GG CIN Y C C F Q+ND ++ ++C +
Sbjct: 1162 SSVCQGGDCINTAGSYDCTCPDGF------------------QLNDNKGCQDI-NECAQP 1202
Query: 301 GSFLC-KNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICD-RGTCINSPGS 474
G LC +G C+ + S+ C C GF S+DG+ C DIDEC N T+CD G C N+ GS
Sbjct: 1203 G--LCGSHGECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNN-TVCDSHGFCDNTAGS 1259
Query: 475 YQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQC 621
++C CY GF G C D NEC +C C N+ GSF C C
Sbjct: 1260 FRCLCYQGFQAPQ--DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 1306
Score = 87.8 bits (216), Expect = 4e-17
Identities = 38/91 (41%), Positives = 53/91 (58%)
Frame = +1
Query: 403 SDIDECTTNPTICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNG 582
++I+ECT NP IC G CIN P Y C CY+G+ KC D +EC++ + LC G
Sbjct: 865 TEINECTVNPDICGAGHCINLPVRYTCICYEGYKFSEQL--RKCVDIDECAQVRHLCSQG 922
Query: 583 VCINIHGSFKCQCNSGYVASSNKQDCISIQD 675
C N GSF C C +G++AS +CI + +
Sbjct: 923 RCENTEGSFLCVCPAGFMASEEGTNCIDVDE 953
Score = 86.3 bits (212), Expect = 1e-16
Identities = 56/198 (28%), Positives = 81/198 (40%), Gaps = 31/198 (15%)
Frame = +1
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSC 489
+C G CI Y C C G++ S + C DIDEC +C +G C N+ GS+ C C
Sbjct: 876 ICGAGHCINLPVRYTCICYEGYKFSEQLRKCVDIDECAQVRHLCSQGRCENTEGSFLCVC 935
Query: 490 YDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQ-CNSGYVAS-----SNK 651
GF G C D +EC +C++G CIN G+F+C+ C+SGY S +
Sbjct: 936 PAGFMASE--EGTNCIDVDECLR-PDMCRDGRCINTAGAFRCEYCDSGYRMSRRGYCEDI 992
Query: 652 QDCISIQDSSDYSAVDDNSKY-CSKCSH------------------------YCAFVNGT 756
+C+ + V+ Y C C+ C + G+
Sbjct: 993 DECLKPSTCPEEQCVNTPGSYQCVPCTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGS 1052
Query: 757 FKCSCPYGMESILDTGLC 810
+ CSC G D C
Sbjct: 1053 YMCSCHRGYSPTPDHRHC 1070
Score = 69.7 bits (169), Expect = 1e-11
Identities = 34/91 (37%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Frame = +1
Query: 439 CDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSE---DKSLCKNGVCINIHGSF 609
C+ G C+ Y C C+DG+ H C D NECSE SLCKN CIN GS+
Sbjct: 1623 CENGRCVRVHEGYTCDCFDGY--HLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSY 1680
Query: 610 KCQCNSGYVASSNKQDCISIQDSSDYSAVDD 702
KC C GY+ S C + + + D
Sbjct: 1681 KCLCLPGYIPSDKPNYCTPLNSALNLDKESD 1711
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/182 (26%), Positives = 70/182 (38%), Gaps = 18/182 (9%)
Frame = +1
Query: 139 GRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSFLCK 318
G C+N + + C C F + G+ C+ E N + D+
Sbjct: 1209 GECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNNTVCDS------------------- 1249
Query: 319 NGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRGTCINSPGSYQCSCYDG 498
+G C + S+ C C GFQ DG+ C D++EC +C C N GS+ C C D
Sbjct: 1250 HGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADE 1309
Query: 499 FTIHNMPGGPKCYDR---------------NEC---SEDKSLCKNGVCINIHGSFKCQCN 624
++ P +C R EC D SLC N + N+ +C C
Sbjct: 1310 NQEYS-PMTGQCRSRVTEDSGVDRQpreEKKECYYNLNDASLCDNVLAPNVTKQ-ECCCT 1367
Query: 625 SG 630
SG
Sbjct: 1368 SG 1369
Score = 67.8 bits (164), Expect = 4e-11
Identities = 58/234 (24%), Positives = 96/234 (41%), Gaps = 27/234 (11%)
Frame = +1
Query: 154 MKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDK-FGSFLCKNGRC 330
M Q R D +D+Q + KK Y +NDA S CD + K C
Sbjct: 1316 MTGQCRSRVTEDSGVDRQpreEKKECYYN---LNDA-------SLCDNVLAPNVTKQECC 1365
Query: 331 IESGSSYECKCNL------GFQESSD-------------------GKICSDIDECTT-NP 432
SG+ + C + G E ++ G+ D DEC
Sbjct: 1366 CTSGAGWGDNCEIFPCPVQGTAEFTEMCPRGKGLVPAGESSYDTGGENYKDADECLLFGE 1425
Query: 433 TICDRGTCINSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFK 612
IC G C+N+ Y+C C G + P +C+D +EC +D + C +G C+N GS+
Sbjct: 1426 EICKNGYCLNTQPGYECYCKQG--TYYDPVKLQCFDMDEC-QDPNSCIDGQCVNTEGSYN 1482
Query: 613 CQCNSGYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCP 774
C C V ++++ C+ +S++ +++ Y C + ++ + CS P
Sbjct: 1483 CFCTHPMVLDASEKRCVQPTESNE--QIEETDVYQDLCWEH---LSEEYVCSRP 1531
Score = 57.8 bits (138), Expect = 4e-08
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = +1
Query: 313 CKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECT---TNPTICDRGTCINSPGSYQC 483
C+NGRC+ Y C C G+ C D++EC+ ++C CIN+ GSY+C
Sbjct: 1623 CENGRCVRVHEGYTCDCFDGYHLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSYKC 1682
Query: 484 SCYDGFTIHNMP 519
C G+ + P
Sbjct: 1683 LCLPGYIPSDKP 1694
Score = 55.5 bits (132), Expect = 2e-07
Identities = 49/239 (20%), Positives = 79/239 (33%), Gaps = 10/239 (4%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C G+C+N + Y C C VLD + C + TE N+ + + +
Sbjct: 1469 CIDGQCVNTEGSYNCFCTHPMVLDASEKRCVQPTE--SNEQIEETDVYQDLCWEHLSEEY 1526
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKIC--SDIDE--------CTTNPTICDRGTCI 459
+C + + EC C G +C D D+ T R +
Sbjct: 1527 VCSRPLVGKQTTYTECCCLYGEAWGMQCALCPMKDSDDYAQLCNIPVTGRRRPYGRDALV 1586
Query: 460 NSPGSYQCSCYDGFTIHNMPGGPKCYDRNECSEDKSLCKNGVCINIHGSFKCQCNSGYVA 639
+ Y F + EC C+NG C+ +H + C C GY
Sbjct: 1587 DFSEQYGPETDPYFIQDRFLNSFEELQAEECGILNG-CENGRCVRVHEGYTCDCFDGYHL 1645
Query: 640 SSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGTFKCSCPYGMESILDTGLCAP 816
K C+ + + S+ +++ C C G++KC C G C P
Sbjct: 1646 DMAKMTCVDVNECSE---LNNRMSLCKNAK--CINTEGSYKCLCLPGYIPSDKPNYCTP 1699
Score = 50.8 bits (120), Expect = 5e-06
Identities = 26/95 (27%), Positives = 42/95 (44%)
Frame = +1
Query: 130 CKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFGSF 309
C+ GRC+ + Y C+C + LD C E +++N+ S
Sbjct: 1623 CENGRCVRVHEGYTCDCFDGYHLDMAKMTCVDVNEC--SELNNRMS-------------- 1666
Query: 310 LCKNGRCIESGSSYECKCNLGFQESSDGKICSDID 414
LCKN +CI + SY+C C G+ S C+ ++
Sbjct: 1667 LCKNAKCINTEGSYKCLCLPGYIPSDKPNYCTPLN 1701
Score = 44.7 bits (104), Expect = 4e-04
Identities = 50/174 (28%), Positives = 66/174 (37%), Gaps = 3/174 (1%)
Frame = +1
Query: 271 FNLKSQCDKFGSFLCKNGRCIESGSSYECKCNLGFQESSDGKICSDIDECTTNPTICDRG 450
FN +C K S+ G + +C G++ ++ C DI+EC +C G
Sbjct: 584 FNKCQKCPKKQSY---------HGYTQMMECLQGYKRVNN-TFCQDINECQLQG-VCPNG 632
Query: 451 TCINSPGSYQCSCYDGFTIHNMPGGPKCY-DRNECSEDKSLCKNGVCINIHGSFKCQCNS 627
C+N+ GSY+CSC GF P C D SE+K C V H C
Sbjct: 633 ECLNTMGSYRCSCKMGFGPD--PTFSSCVPDPPVISEEKGPCYRLVSPGRH------CMH 684
Query: 628 GYVASSNKQDCISIQDSSDYSAVDDNSKYCSKCSHYCAFVNGT--FKCSCPYGM 783
KQ C S +C KC + GT FK CP GM
Sbjct: 685 PLSVHLTKQICCC-------SVGKAWGPHCEKCP-----LPGTAAFKEICPGGM 726
Score = 36.2 bits (82), Expect = 0.12
Identities = 25/80 (31%), Positives = 36/80 (45%)
Frame = +1
Query: 124 EQCKGGRCINMKNQYRCECLPDFVLDKQGQACKKRTEYKPNQMNDAASSFNLKSQCDKFG 303
E CK G C+N + Y C C KQG T Y P ++ F++ +C
Sbjct: 1426 EICKNGYCLNTQPGYECYC-------KQG------TYYDPVKL----QCFDM-DECQDPN 1467
Query: 304 SFLCKNGRCIESGSSYECKC 363
S C +G+C+ + SY C C
Sbjct: 1468 S--CIDGQCVNTEGSYNCFC 1485
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,137,411
Number of Sequences: 369166
Number of extensions: 2197959
Number of successful extensions: 13787
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5957
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8615
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8838279920
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)