Planaria EST Database


DrC_01837

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01837
         (788 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8IPH9|SLOB_DROME  Slowpoke-binding protein                     65   3e-10
sp|P41743|KPCI_HUMAN  Protein kinase C, iota type (nPKC-iota...    50   9e-06
sp|Q62074|KPCI_MOUSE  Protein kinase C, iota type (nPKC-iota...    50   9e-06
sp|Q5R4K9|KPCI_PONPY  Protein kinase C, iota type (nPKC-iota)      50   9e-06
sp|Q90XF2|KPCI_BRARE  Protein kinase C, iota type (nPKC-iota...    50   9e-06
sp|P13678|KPC3_DROME  Protein kinase C (PKC) (dPKC98F)             48   3e-05
sp|Q05513|KPCZ_HUMAN  Protein kinase C, zeta type (nPKC-zeta)      47   6e-05
sp|P54644|KRAC_DICDI  RAC-family serine/threonine-protein ki...    47   6e-05
sp|P09217|KPCZ_RAT  Protein kinase C, zeta type (nPKC-zeta)        47   6e-05
sp|Q02956|KPCZ_MOUSE  Protein kinase C, zeta type (nPKC-zeta)      47   6e-05
>sp|Q8IPH9|SLOB_DROME Slowpoke-binding protein
          Length = 515

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 63/221 (28%), Positives = 103/221 (46%), Gaps = 10/221 (4%)
 Frame = +1

Query: 43  IIRLFSELGSLHDFMCKVKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGI 222
           ++  F+  GSL D + K +   P   KY  +      ++ +   GRQIL  L +L ++G 
Sbjct: 262 LVTPFNSRGSLKDLIYKAQWNEPWARKYT-RKPNGLPVSQVQRLGRQILEALLFLKERGF 320

Query: 223 P-YGHLHLRNVLLFTEDRCGLTDIENSVLGLIPQDRHFYVGILKKLT-FEEIDIYCFGRI 396
           P +GHLH  NV+L       L+ +EN +LGL    R   V   + +T  E +DI CFG +
Sbjct: 321 PLHGHLHSGNVIL-QNGAARLSGLENGLLGL--SSRINAVMWSRSVTEIENVDIVCFGHL 377

Query: 397 MYEMIFGE----PLNSTFIISDDKLKWPTPAIREFMFSVLTEVVLK--SGF-PTIDNLLE 555
           +YEM  G+    P  S  ++  +   +P           +  ++ +  SG  P++++L+ 
Sbjct: 378 LYEMCTGQELTTPKPSMRVLEMELQHYPQIGQTRKQILEILGLIFEPPSGVCPSVEDLVL 437

Query: 556 LTLFKSCSPKLIDKSPFK-ISPSCKELLLSTQQYSLKRLIA 675
             LF+S   + +    F  I PS     L+  Q   KR  A
Sbjct: 438 CDLFRSIDLRELRGPCFSTIKPSLSRSTLNLLQAVKKRQCA 478
>sp|P41743|KPCI_HUMAN Protein kinase C, iota type (nPKC-iota) (Atypical protein kinase
           C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota)
          Length = 587

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I L L YLH++GI Y  L L NVLL +E  
Sbjct: 323 IEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGH 382

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 383 IKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS 442

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
                  SD+    P     +++F V+ E
Sbjct: 443 PFDIVGSSDN----PDQNTEDYLFQVILE 467
>sp|Q62074|KPCI_MOUSE Protein kinase C, iota type (nPKC-iota) (Atypical protein kinase
           C-lambda/iota) (aPKC-lambda/iota)
          Length = 586

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I L L YLH++GI Y  L L NVLL +E  
Sbjct: 322 IEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGH 381

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 382 IKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS 441

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
                  SD+    P     +++F V+ E
Sbjct: 442 PFDIVGSSDN----PDQNTEDYLFQVILE 466
>sp|Q5R4K9|KPCI_PONPY Protein kinase C, iota type (nPKC-iota)
          Length = 587

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I L L YLH++GI Y  L L NVLL +E  
Sbjct: 323 IEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGH 382

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 383 IKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS 442

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
                  SD+    P     +++F V+ E
Sbjct: 443 PFDIVGSSDN----PDQNTEDYLFQVILE 467
>sp|Q90XF2|KPCI_BRARE Protein kinase C, iota type (nPKC-iota) (Atypical protein kinase
           C-lambda/iota) (aPKC-lambda/iota) (Heart and soul
           protein)
          Length = 588

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I L L YLH++GI Y  L L NVLL +E  
Sbjct: 324 IEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGH 383

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 384 IKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS 443

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
                  SD+    P     +++F V+ E
Sbjct: 444 PFDIVGSSDN----PDQNTEDYLFQVILE 468
>sp|P13678|KPC3_DROME Protein kinase C (PKC) (dPKC98F)
          Length = 634

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 10/117 (8%)
 Frame = +1

Query: 103 VNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDRCGL 282
           VN   L + +Q  +    +  + +  ++ L L++LH  G+ Y  L L N+LL  E  C L
Sbjct: 384 VNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKL 443

Query: 283 TD-------IENSVLGLIPQDRHFYVG--ILKKLTF-EEIDIYCFGRIMYEMIFGEP 423
            D       I N +L         Y+   ILK+  +   +D +  G +MYEM+ G+P
Sbjct: 444 ADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQP 500
>sp|Q05513|KPCZ_HUMAN Protein kinase C, zeta type (nPKC-zeta)
          Length = 592

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I + L +LH++GI Y  L L NVLL  +  
Sbjct: 330 IEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGH 389

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 390 IKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAG-- 447

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
             S F I  D    P     +++F V+ E
Sbjct: 448 -RSPFDIITDN---PDMNTEDYLFQVILE 472
>sp|P54644|KRAC_DICDI RAC-family serine/threonine-protein kinase homolog
          Length = 444

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 11/118 (9%)
 Frame = +1

Query: 103 VNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDRCGL 282
           VN   L Y++Q  K    + +  +G +I+L L++LH  G+ Y  L   N+LL  E    +
Sbjct: 200 VNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEGHICM 259

Query: 283 TDIENSVLGLI-PQDR-HFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
           TD      GL+ P D+   + G  + L  E         ++D + FG ++YEM+ G P
Sbjct: 260 TDFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGLP 317
>sp|P09217|KPCZ_RAT Protein kinase C, zeta type (nPKC-zeta)
          Length = 592

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I + L +LH++GI Y  L L NVLL  +  
Sbjct: 330 IEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGH 389

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 390 IKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAG-- 447

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
             S F I  D    P     +++F V+ E
Sbjct: 448 -RSPFDIITDN---PDMNTEDYLFQVILE 472
>sp|Q02956|KPCZ_MOUSE Protein kinase C, zeta type (nPKC-zeta)
          Length = 592

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
 Frame = +1

Query: 94  VKPVNPIILKYNVQNGKSTLINHLSLFGRQILLGLKYLHDKGIPYGHLHLRNVLLFTEDR 273
           ++ VN   L +++Q  +     H   +  +I + L +LH++GI Y  L L NVLL  +  
Sbjct: 330 IEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGH 389

Query: 274 CGLTDIENSVLGLIPQD-RHFYVGILKKLTFE---------EIDIYCFGRIMYEMIFGEP 423
             LTD      GL P D    + G    +  E          +D +  G +M+EM+ G  
Sbjct: 390 IKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAG-- 447

Query: 424 LNSTFIISDDKLKWPTPAIREFMFSVLTE 510
             S F I  D    P     +++F V+ E
Sbjct: 448 -RSPFDIITDN---PDMNTEDYLFQVILE 472
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,803,097
Number of Sequences: 369166
Number of extensions: 1936519
Number of successful extensions: 6420
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5988
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6258
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7454154400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)