Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01742
(559 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55262|ADK_CRIGR Adenosine kinase (AK) (Adenosine 5'-pho... 180 2e-45
sp|P55263|ADK_HUMAN Adenosine kinase (AK) (Adenosine 5'-pho... 177 2e-44
sp|Q9LZG0|ADK2_ARATH Adenosine kinase 2 (AK 2) (Adenosine 5... 176 3e-44
sp|P55264|ADK_MOUSE Adenosine kinase (AK) (Adenosine 5'-pho... 175 8e-44
sp|Q9SF85|ADK1_ARATH Adenosine kinase 1 (AK 1) (Adenosine 5... 173 2e-43
sp|Q64640|ADK_RAT Adenosine kinase (AK) (Adenosine 5'-phosp... 171 1e-42
sp|O49923|ADK_PHYPA Adenosine kinase (AK) (Adenosine 5'-pho... 164 1e-40
sp|P47143|ADK_YEAST Adenosine kinase 149 6e-36
sp|O93919|ADK_SCHCO Adenosine kinase 142 6e-34
sp|P78825|ADK_SCHPO Adenosine kinase 132 6e-31
>sp|P55262|ADK_CRIGR Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 361
Score = 180 bits (456), Expect = 2e-45
Identities = 92/188 (48%), Positives = 128/188 (68%), Gaps = 2/188 (1%)
Frame = +2
Query: 2 MTDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPG 181
+++ +LFGMGNPLLDISA V+ D L KY LK ND IL EEKH ++DE++ +KV+Y G
Sbjct: 20 LSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEEKHKELFDELVRKFKVEYHAG 79
Query: 182 GATQNTIKVAQWVLKKKY-ASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGV 358
G+TQN+IKVAQW+++K + A+ + GCI DK+G+ LK E V Y Y + + TG
Sbjct: 80 GSTQNSIKVAQWMIQKPHKAATFFGCIGIDKFGEILKSKAAEAHVDAHY-YEQNEQPTGT 138
Query: 359 CACLLTGHNRSLVTSLGAA-CKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKV 535
CA +TG NRSLV +L AA C HLD W VE++ V+YI+ FF+T E+++KV
Sbjct: 139 CAACITGDNRSLVANLAAANCYKKEKHLDLENNWVLVEKARVYYIAGFFLTVSPESVLKV 198
Query: 536 AKHSMENN 559
A+++ ENN
Sbjct: 199 ARYAAENN 206
>sp|P55263|ADK_HUMAN Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 362
Score = 177 bits (448), Expect = 2e-44
Identities = 90/188 (47%), Positives = 127/188 (67%), Gaps = 2/188 (1%)
Frame = +2
Query: 2 MTDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPG 181
+ + +LFGMGNPLLDISA V+ D L KY LK ND IL E+KH ++DE+++ +KV+Y G
Sbjct: 21 LRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAG 80
Query: 182 GATQNTIKVAQWVLKKKY-ASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGV 358
G+TQN+IKVAQW++++ + A+ + GCI DK+G+ LK E V Y Y + + TG
Sbjct: 81 GSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHY-YEQNEQPTGT 139
Query: 359 CACLLTGHNRSLVTSLGAA-CKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKV 535
CA +TG NRSL+ +L AA C HLD + W VE++ V YI+ FF+T E+++KV
Sbjct: 140 CAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKV 199
Query: 536 AKHSMENN 559
A H+ ENN
Sbjct: 200 AHHASENN 207
>sp|Q9LZG0|ADK2_ARATH Adenosine kinase 2 (AK 2) (Adenosine 5'-phosphotransferase 2)
Length = 345
Score = 176 bits (446), Expect = 3e-44
Identities = 90/184 (48%), Positives = 121/184 (65%)
Frame = +2
Query: 8 DKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPGGA 187
D +L GMGNPLLDISA V+ + L KYD+K N+AIL E+KHLP+YDEM + V+YI GGA
Sbjct: 8 DGILLGMGNPLLDISAVVDDEFLTKYDIKLNNAILAEDKHLPMYDEMSSKFNVEYIAGGA 67
Query: 188 TQNTIKVAQWVLKKKYASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGVCAC 367
TQN+IKVAQW+L+ A+ Y+G I DKYG+ +K+ GV Y Y TG C
Sbjct: 68 TQNSIKVAQWMLQIPGATSYMGSIGKDKYGEAMKKDATAAGVNVHY-YEDESAPTGTCGV 126
Query: 368 LLTGHNRSLVTSLGAACKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKVAKHS 547
+ G RSL+ +L AA + VDHL K E W VE++ +YI+ FF+T E++ V++H+
Sbjct: 127 CVVGGERSLIANLSAANCYKVDHLKKPENWALVEKAKFYYIAGFFLTVSPESIQLVSEHA 186
Query: 548 MENN 559
NN
Sbjct: 187 AANN 190
>sp|P55264|ADK_MOUSE Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 361
Score = 175 bits (443), Expect = 8e-44
Identities = 88/188 (46%), Positives = 129/188 (68%), Gaps = 2/188 (1%)
Frame = +2
Query: 2 MTDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPG 181
+++ +LFGMGNPLLDISA V+ D L KY LK ND IL E+KH ++DE+++ +KV+Y G
Sbjct: 20 LSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAG 79
Query: 182 GATQNTIKVAQWVLKKKY-ASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGV 358
G+TQN++KVAQW++++ + A+ + GCI DK+G+ LK + V Y Y + + TG
Sbjct: 80 GSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHY-YEQNEQPTGT 138
Query: 359 CACLLTGHNRSLVTSLGAA-CKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKV 535
CA +TG NRSLV +L AA C HLD W VE++ V+YI+ FF+T E+++KV
Sbjct: 139 CAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVLKV 198
Query: 536 AKHSMENN 559
A+++ ENN
Sbjct: 199 ARYAAENN 206
>sp|Q9SF85|ADK1_ARATH Adenosine kinase 1 (AK 1) (Adenosine 5'-phosphotransferase 1)
Length = 344
Score = 173 bits (439), Expect = 2e-43
Identities = 88/184 (47%), Positives = 120/184 (65%)
Frame = +2
Query: 8 DKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPGGA 187
D +L GMGNPLLD+SA V+ L KYD+K N+AIL E+KHLP+YDEM + + V+YI GGA
Sbjct: 7 DGILLGMGNPLLDVSAVVDQQFLDKYDIKLNNAILAEDKHLPMYDEMSQKFNVEYIAGGA 66
Query: 188 TQNTIKVAQWVLKKKYASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGVCAC 367
TQN+IKVAQW+L+ A+ Y+G I DKYG+ +K+ GV Y Y TG C
Sbjct: 67 TQNSIKVAQWMLQVPGATSYMGSIGKDKYGEAMKKDATAAGVYVHY-YEDEATPTGTCGV 125
Query: 368 LLTGHNRSLVTSLGAACKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKVAKHS 547
+ G RSL+ +L AA + V+HL K E W VE++ +YI+ FF+T E++ V +H+
Sbjct: 126 CVLGGERSLIANLSAANCYKVEHLKKPENWALVEKAKFYYIAGFFLTVSPESIQLVREHA 185
Query: 548 MENN 559
NN
Sbjct: 186 AANN 189
>sp|Q64640|ADK_RAT Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 361
Score = 171 bits (433), Expect = 1e-42
Identities = 86/188 (45%), Positives = 128/188 (68%), Gaps = 2/188 (1%)
Frame = +2
Query: 2 MTDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPG 181
+++ +LFGMGNPLLDISA V+ D L KY LK ND IL E+KH ++DE+++ +KV+Y G
Sbjct: 20 LSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAG 79
Query: 182 GATQNTIKVAQWVLKKKY-ASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGV 358
G+TQN++KVAQW++++ + A+ + GCI DK+G+ LK V Y Y + + TG
Sbjct: 80 GSTQNSMKVAQWMIQEPHRAATFFGCIGIDKFGEILKSKAANAHVDAHY-YEQNEQPTGT 138
Query: 359 CACLLTGHNRSLVTSLGAA-CKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKV 535
CA ++G NRSLV +L AA C HLD W VE++ V+YI+ FF+T E+++K+
Sbjct: 139 CAACISGGNRSLVANLRAANCYKKEKHLDLENNWMLVEKARVYYIAGFFLTVSPESVLKM 198
Query: 536 AKHSMENN 559
A+++ ENN
Sbjct: 199 ARYAAENN 206
>sp|O49923|ADK_PHYPA Adenosine kinase (AK) (Adenosine 5'-phosphotransferase)
Length = 343
Score = 164 bits (416), Expect = 1e-40
Identities = 84/183 (45%), Positives = 119/183 (65%)
Frame = +2
Query: 5 TDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPGG 184
++ +L GMGNPLLDIS V+ L+KY L N+AIL E+KHLP+Y E+ N V+YI GG
Sbjct: 3 SEGVLLGMGNPLLDISCVVDDAFLEKYGLTLNNAILAEDKHLPMYKELAANPDVEYIAGG 62
Query: 185 ATQNTIKVAQWVLKKKYASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGVCA 364
ATQNTI++AQW+L + A+ Y GC+ D+YG ++ + E GV Y ++ TG C
Sbjct: 63 ATQNTIRIAQWMLGESNATSYFGCVGKDEYGDRMFKLASEGGVNIRYDVDE-DLPTGTCG 121
Query: 365 CLLTGHNRSLVTSLGAACKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKVAKH 544
L+ RSLV +L AA K+ +DHL K E W +VE++ Y + FF+T E+++ VAKH
Sbjct: 122 VLVVKGERSLVANLSAANKYKIDHLKKPENWAFVEKAKYIYSAGFFLTVSPESMMTVAKH 181
Query: 545 SME 553
+ E
Sbjct: 182 AAE 184
>sp|P47143|ADK_YEAST Adenosine kinase
Length = 340
Score = 149 bits (375), Expect = 6e-36
Identities = 82/182 (45%), Positives = 115/182 (63%), Gaps = 4/182 (2%)
Frame = +2
Query: 26 MGNPLLDISAEVNLDLLKKYDLKENDAILVEEKH----LPIYDEMIENYKVDYIPGGATQ 193
+GNPLLD A+V + L KY LKENDAILV+ K + I+DE+++ + + GGA Q
Sbjct: 8 LGNPLLDFQADVTAEYLAKYSLKENDAILVDAKSGDAKMAIFDELLQMPETKLVAGGAAQ 67
Query: 194 NTIKVAQWVLKKKYASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGVCACLL 373
NT + A +VL VY G + DK+ ++L E+ GV+++YQ + TG CA L+
Sbjct: 68 NTARGAAYVLGAGQV-VYFGSVGKDKFSERLLNENEKAGVKSMYQV-QNDIGTGKCAALI 125
Query: 374 TGHNRSLVTSLGAACKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKVAKHSME 553
TGHNRSLVT LGAA FT DHLDK W VE + +FYI F +T +A++K+ +H+ E
Sbjct: 126 TGHNRSLVTDLGAANFFTPDHLDKH--WDLVEAAKLFYIGGFHLTVSPDAIVKLGQHAKE 183
Query: 554 NN 559
N+
Sbjct: 184 NS 185
>sp|O93919|ADK_SCHCO Adenosine kinase
Length = 344
Score = 142 bits (358), Expect = 6e-34
Identities = 77/182 (42%), Positives = 110/182 (60%)
Frame = +2
Query: 2 MTDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPG 181
M+ LF MGNPLLD+ LL+KY LK NDAIL EEKHL +YDE+++ ++V Y+ G
Sbjct: 1 MSSYKLFCMGNPLLDLQVRDGEKLLEKYGLKSNDAILAEEKHLLLYDEIVKEHEVTYVAG 60
Query: 182 GATQNTIKVAQWVLKKKYASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPESTGVC 361
GA QN + A + L K + VY GC+ DD ++LK + + G+ Y KG E TG C
Sbjct: 61 GAAQNAARGAAYCLPPK-SVVYTGCVGDDDLAEQLKAANKREGLDEAYLVKKG-EKTGAC 118
Query: 362 ACLLTGHNRSLVTSLGAACKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIKVAK 541
A ++TGH+RSLVT+L AA KF HL + V+ +Y+ +F+T + +++A
Sbjct: 119 AVIITGHDRSLVTTLRAAEKFEQSHLSSEAVAPLVDAVQFYYMEGYFVTHGLASALELAG 178
Query: 542 HS 547
S
Sbjct: 179 KS 180
>sp|P78825|ADK_SCHPO Adenosine kinase
Length = 340
Score = 132 bits (332), Expect = 6e-31
Identities = 75/189 (39%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = +2
Query: 2 MTDKLLFGMGNPLLDISAEVNLDLLKKYDLKENDAILVEEKHLPIYDEMIENYKVDYIPG 181
M+ +LFG+ NPLLD L+KY LK NDA+L E + IY E V Y G
Sbjct: 1 MSSYILFGLENPLLDYYVGGETATLEKYGLKSNDAVLASESQMGIYKEPC----VSYSAG 56
Query: 182 GATQNTIKVAQWVLKKKYASVYVGCIKDDKYGKKLKESCEEIGVRTLYQYNKGPES-TGV 358
GA QN+ + AQ+VL ++V+ GC+ DK+ L ES E+ G+R+ +++ P + TGV
Sbjct: 57 GAAQNSCRAAQYVLPPN-STVFAGCVGQDKFADMLLESNEKAGLRS--EFSVDPTTPTGV 113
Query: 359 CACLLTGHN--RSLVTSLGAACKFTVDHLDKSEIWKYVEQSGVFYISSFFITSCHEALIK 532
CA +L+ +N RSL T+LGAA + + L + +WK+VE++ V Y+ F +T E+++
Sbjct: 114 CAVVLSNNNKNRSLCTNLGAANNYKLKDLQQPNVWKFVEEAKVIYVGGFHLTVSPESMLC 173
Query: 533 VAKHSMENN 559
+A+H+ ENN
Sbjct: 174 LAQHANENN 182
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,753,455
Number of Sequences: 369166
Number of extensions: 1149264
Number of successful extensions: 2982
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2921
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2960
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3980545740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)