Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01677
(734 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51958|CDC2_CARAU Cell division control protein 2 homolo... 259 7e-69
sp|P43450|CDK2_CARAU Cell division protein kinase 2 256 4e-68
sp|P23572|CDC2_DROME Cell division control protein 2 homolo... 255 7e-68
sp|P35567|CDC21_XENLA Cell division control protein 2 homol... 255 1e-67
sp|P24033|CDC22_XENLA Cell division control protein 2 homol... 254 1e-67
sp|P23111|CDC2_MAIZE Cell division control protein 2 homolo... 252 8e-67
sp|P06493|CDC2_HUMAN Cell division control protein 2 homolo... 250 3e-66
sp|P29618|CDC21_ORYSA Cell division control protein 2 homol... 249 4e-66
sp|Q9W739|CDC2_RANDY Cell division control protein 2 homolo... 249 5e-66
sp|P93101|CDC2_CHERU Cell division control protein 2 homolo... 249 7e-66
>sp|P51958|CDC2_CARAU Cell division control protein 2 homolog (p34 protein kinase)
(Cyclin-dependent kinase 1) (CDK1)
Length = 302
Score = 259 bits (661), Expect = 7e-69
Identities = 124/229 (54%), Positives = 165/229 (72%), Gaps = 2/229 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK NK T + A+KKIR E++E+G+ ST +REIS LKEL HPN+V L + ++ KLY
Sbjct: 18 VYKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLY 77
Query: 184 LVFEXXXXXXXXXXXNTENP--MNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVD 357
LVFE + + M+ ++K + YQI++G+LFCH RR +HRDLKPQNLL+D
Sbjct: 78 LVFEFLSMDLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLID 137
Query: 358 TNKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSE 537
NK VIKLADFGLAR +G P++ THEVVTLWYRAPE+++ A RYS +DVWS+ I +E
Sbjct: 138 -NKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGASRYSTPVDVWSIGTIFAE 196
Query: 538 MITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR 684
+ T KPLF GDSEIDQLF IF+ LGTP++ +WP+++ LP + FP W+
Sbjct: 197 LATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKNTFPKWK 245
>sp|P43450|CDK2_CARAU Cell division protein kinase 2
Length = 298
Score = 256 bits (654), Expect = 4e-68
Identities = 124/227 (54%), Positives = 159/227 (70%), Gaps = 1/227 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK NK+T E A+KKIR + + +G+ ST +REIS LKEL HPNIV LH I + KLY
Sbjct: 18 VYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLHDVIHTENKLY 77
Query: 184 LVFEXXXXXXXXXXXN-TENPMNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVDT 360
LVFE + T ++ ++K + +Q++QGL FCH+ R +HRDLKPQNLL++
Sbjct: 78 LVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINA 137
Query: 361 NKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSEM 540
IKLADFGLAR +G P++ THEVVTLWYRAPEI++ K YS A+D+WS+ CI +EM
Sbjct: 138 QG-EIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEM 196
Query: 541 ITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIW 681
IT K LF GDSEIDQLF IF+ LGTPD +IWP + +P + P FP W
Sbjct: 197 ITRKALFPGDSEIDQLFRIFRTLGTPDESIWPGVTSMPDYKPSFPKW 243
>sp|P23572|CDC2_DROME Cell division control protein 2 homolog (p34 protein kinase)
Length = 297
Score = 255 bits (652), Expect = 7e-68
Identities = 119/239 (49%), Positives = 167/239 (69%), Gaps = 3/239 (1%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK N++T + A+KKIR E+D++G+ ST +REIS LKEL H NIVCL + E+ ++Y
Sbjct: 18 VYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIY 77
Query: 184 LVFEXXXXXXXXXXXN--TENPMNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVD 357
L+FE + + M + +++ + YQI +LFCH RR +HRDLKPQNLL+D
Sbjct: 78 LIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLID 137
Query: 358 TNKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSE 537
+ +IK+ADFGL R++G P++ THE+VTLWYRAPE+++ + RYSC +D+WS+ CI +E
Sbjct: 138 KSG-LIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAE 196
Query: 538 MITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWRFD-LRNHLKD 711
M T KPLFQGDSEIDQLF +F++L TP +IWP + LP + FP W + L N LK+
Sbjct: 197 MATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKN 255
>sp|P35567|CDC21_XENLA Cell division control protein 2 homolog 1 (p34 protein kinase 1)
Length = 302
Score = 255 bits (651), Expect = 1e-67
Identities = 121/229 (52%), Positives = 165/229 (72%), Gaps = 2/229 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK +K T + A+KKIR EN+E+G+ ST +REIS LKEL HPNIVCL + + +LY
Sbjct: 18 VYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLY 77
Query: 184 LVFEXXXXXXXXXXXNTENP--MNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVD 357
L+FE + + ++T ++K + YQI+QG++FCH+RR +HRDLKPQNLL+D
Sbjct: 78 LIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID 137
Query: 358 TNKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSE 537
+ K VIKLADFGLAR +G P++ THEVVTLWYRAPE+++ + RYS +DVWS+ I +E
Sbjct: 138 S-KGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAE 196
Query: 538 MITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR 684
+ T KPLF GDSEIDQLF IF+ LGTP++ +WP ++ L + FP W+
Sbjct: 197 IATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNSFPKWK 245
>sp|P24033|CDC22_XENLA Cell division control protein 2 homolog 2 (p34 protein kinase 2)
Length = 302
Score = 254 bits (650), Expect = 1e-67
Identities = 122/229 (53%), Positives = 164/229 (71%), Gaps = 2/229 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK +K T + A+KKIR EN+E+G+ ST +REIS LKEL HPNIVCL + + +LY
Sbjct: 18 VYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLY 77
Query: 184 LVFEXXXXXXXXXXXNTENP--MNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVD 357
L+FE + + ++T ++K + YQI+QG++FCH+R +HRDLKPQNLL+D
Sbjct: 78 LIFEFLSMDVKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRGVLHRDLKPQNLLID 137
Query: 358 TNKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSE 537
NK VIKLADFGLAR +G P++ THEVVTLWYRAPE+++ + RYS +DVWSV I +E
Sbjct: 138 -NKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSVGTIFAE 196
Query: 538 MITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR 684
+ T KPLF GDSEIDQLF IF+ LGTP++ +WP ++ L + FP W+
Sbjct: 197 IATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPEVESLQDYKNTFPKWK 245
>sp|P23111|CDC2_MAIZE Cell division control protein 2 homolog (p34cdc2)
Length = 294
Score = 252 bits (643), Expect = 8e-67
Identities = 118/228 (51%), Positives = 158/228 (69%), Gaps = 1/228 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK L+K TNE A+KKIR E +++G+ ST +REIS LKE+ H NIV LH + + ++Y
Sbjct: 18 VYKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLKEMNHGNIVRLHDVVHSEKRIY 77
Query: 184 LVFEXXXXXXXXXXXNT-ENPMNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVDT 360
LVFE + E N ++K + YQI+ G+ +CH+ R +HRDLKPQNLL+D
Sbjct: 78 LVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILHGVAYCHSHRVLHRDLKPQNLLIDR 137
Query: 361 NKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSEM 540
+KLADFGLAR +G P++ THEVVTLWYRAPEI++ A++YS +DVWSV CI +EM
Sbjct: 138 RTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGARQYSTPVDVWSVGCIFAEM 197
Query: 541 ITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR 684
+ KPLF GDSEID+LF IF++LGTP+ WP + LP + FP W+
Sbjct: 198 VNQKPLFPGDSEIDELFKIFRILGTPNEQSWPGVSCLPDFKTAFPRWQ 245
>sp|P06493|CDC2_HUMAN Cell division control protein 2 homolog (p34 protein kinase)
(Cyclin-dependent kinase 1) (CDK1)
Length = 297
Score = 250 bits (638), Expect = 3e-66
Identities = 123/246 (50%), Positives = 172/246 (69%), Gaps = 3/246 (1%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK +K T + A+KKIR E++E+G+ ST +REIS LKEL HPNIV L + + +LY
Sbjct: 18 VYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLY 77
Query: 184 LVFEXXXXXXXXXXXNTE--NPMNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVD 357
L+FE + M++ ++K + YQI+QG++FCH+RR +HRDLKPQNLL+D
Sbjct: 78 LIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLID 137
Query: 358 TNKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSE 537
+K IKLADFGLAR +G PI+ THEVVTLWYR+PE+++ + RYS +D+WS+ I +E
Sbjct: 138 -DKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAE 196
Query: 538 MITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR-FDLRNHLKDY 714
+ T KPLF GDSEIDQLF IF+ LGTP++ +WP ++ L + FP W+ L +H+K+
Sbjct: 197 LATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKN- 255
Query: 715 VDETCL 732
+DE L
Sbjct: 256 LDENGL 261
>sp|P29618|CDC21_ORYSA Cell division control protein 2 homolog 1
Length = 294
Score = 249 bits (637), Expect = 4e-66
Identities = 115/228 (50%), Positives = 159/228 (69%), Gaps = 1/228 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VY+ +K+TNE A+KKIR E +++G+ ST +REIS LKE+ H NIV LH I + ++Y
Sbjct: 18 VYRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMHHGNIVRLHDVIHSEKRIY 77
Query: 184 LVFEXXXXXXXXXXXNT-ENPMNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVDT 360
LVFE + E N ++K + YQI++G+ +CH+ R +HRDLKPQNLL+D
Sbjct: 78 LVFEYLDLDLKKFMDSCPEFAKNPTLIKSYLYQILRGVAYCHSHRVLHRDLKPQNLLIDR 137
Query: 361 NKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSEM 540
+KLADFGLAR +G P++ THEVVTLWYRAPEI++ +++YS +D+WSV CI +EM
Sbjct: 138 RTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRQYSTPVDMWSVGCIFAEM 197
Query: 541 ITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR 684
+ KPLF GDSEID+LF IF++LGTP+ WP + LP + FP W+
Sbjct: 198 VNQKPLFPGDSEIDELFKIFRVLGTPNEQSWPGVSSLPDYKSAFPKWQ 245
>sp|Q9W739|CDC2_RANDY Cell division control protein 2 homolog (p34 protein kinase)
Length = 302
Score = 249 bits (636), Expect = 5e-66
Identities = 118/229 (51%), Positives = 162/229 (70%), Gaps = 2/229 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK ++K T + A+KKIR EN+E+G+ ST +REIS LKEL HPNIVCL + + +LY
Sbjct: 18 VYKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLY 77
Query: 184 LVFEXXXXXXXXXXXNTENP--MNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVD 357
L+FE + + + ++K + YQI+QG++FCH RR +HRDLKPQNLL+D
Sbjct: 78 LIFEFLSMDLKKYLDSIPSGQYLEAMLVKSYLYQILQGIIFCHARRVLHRDLKPQNLLID 137
Query: 358 TNKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSE 537
+ K VIKLADFGLAR +G P++ THEVVTLWYRAPE+++ + RYS +DVWS+ I +E
Sbjct: 138 S-KGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAE 196
Query: 538 MITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIWR 684
+ + KPLF GDSEIDQLF I +L GTP++ +WP ++ L + FP W+
Sbjct: 197 IASKKPLFHGDSEIDQLFRISELWGTPNNEVWPEVESLQDYKNTFPKWK 245
>sp|P93101|CDC2_CHERU Cell division control protein 2 homolog (p34cdc2)
Length = 294
Score = 249 bits (635), Expect = 7e-66
Identities = 116/227 (51%), Positives = 156/227 (68%), Gaps = 1/227 (0%)
Frame = +1
Query: 4 VYKCLNKITNEYAAIKKIRSENDEDGISSTTLREISTLKELVHPNIVCLHQTITEKGKLY 183
VYK +K+TNE A+KKIR E +++G+ ST +REIS LKE+ H NIV L + + +LY
Sbjct: 18 VYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHSEKRLY 77
Query: 184 LVFEXXXXXXXXXXXNTEN-PMNTHIMKRFSYQIMQGLLFCHTRRFMHRDLKPQNLLVDT 360
LVFE + + + ++KRF YQI++G+ +CH+ R +HRDLKPQNLL+D
Sbjct: 78 LVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYCHSHRVLHRDLKPQNLLIDR 137
Query: 361 NKCVIKLADFGLARTYGAPIKPLTHEVVTLWYRAPEIIMNAKRYSCAIDVWSVACIMSEM 540
+KLADFGLAR +G P++ THEVVTLWYRAPEI++ ++ YS +DVWSV CI +EM
Sbjct: 138 QTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEM 197
Query: 541 ITSKPLFQGDSEIDQLFVIFKLLGTPDSNIWPNLDKLPGWNPLFPIW 681
+ KPLF GDSEID+LF IF+ LGTP+ WP + LP + FP W
Sbjct: 198 VNQKPLFPGDSEIDELFKIFRTLGTPNEETWPGVTSLPDFKSSFPKW 244
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,562,070
Number of Sequences: 369166
Number of extensions: 1680255
Number of successful extensions: 7688
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5298
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5552
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6582889600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)