Planaria EST Database


DrC_01631

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01631
         (810 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9H2K2|TNKS2_HUMAN  Tankyrase 2 (TANK2) (Tankyrase II) (T...    63   1e-09
sp|P16157|ANK1_HUMAN  Ankyrin-1 (Erythrocyte ankyrin) (Ankyr...    62   1e-09
sp|Q02357|ANK1_MOUSE  Ankyrin-1 (Erythrocyte ankyrin)              62   2e-09
sp|Q12955|ANK3_HUMAN  Ankyrin-3 (ANK-3) (Ankyrin G)                60   9e-09
sp|O95271|TNKS1_HUMAN  Tankyrase 1 (TANK1) (Tankyrase I) (TN...    59   1e-08
sp|P57078|RIPK4_HUMAN  Serine/threonine-protein kinase RIPK4...    59   1e-08
sp|Q13418|ILK1_HUMAN  Integrin-linked protein kinase 1 (ILK-...    56   1e-07
sp|P57043|ILK2_HUMAN  Integrin-linked protein kinase 2 (ILK-2)     56   1e-07
sp|P57044|ILK_CAVPO  Integrin-linked protein kinase (Beta-in...    56   1e-07
sp|Q9H9B1|EHMT1_HUMAN  Histone-lysine N-methyltransferase, H...    54   4e-07
>sp|Q9H2K2|TNKS2_HUMAN Tankyrase 2 (TANK2) (Tankyrase II) (TNKS-2) (TRF1-interacting
           ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like
           protein) (Tankyrase-related protein)
          Length = 1166

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 33/98 (33%), Positives = 48/98 (48%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   GR  +V+ L+ N   + +                  G  P+H AC FGH ++
Sbjct: 61  PLHFAAGFGRKDVVEYLLQNGANVQA--------------RDDGGLIPLHNACSFGHAEV 106

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           V LL+ +  D NA + W Y P+H A  KG ID+  +L+
Sbjct: 107 VNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 144

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 27/98 (27%), Positives = 50/98 (51%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A    R+ +V+ L+ +  ++ +                  G  P+H AC +GH ++
Sbjct: 529 PLHFAAGYNRVSVVEYLLQHGADVHA--------------KDKGGLVPLHNACSYGHYEV 574

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
            +LL+ +   +N ++ WK+ P+H A  KG  +I K+L+
Sbjct: 575 AELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLL 612

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 21/55 (38%), Positives = 34/55 (61%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
           G  P+H A  +GH+D+  LLI     +NA++KW + P+H A +KG   +  +L+A
Sbjct: 712 GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLA 766

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 23/99 (23%), Positives = 50/99 (50%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A    R+ +V++L+ +  ++ +                     P+H AC +GH ++
Sbjct: 214 PLHLAAGYNRVKIVQLLLQHGADVHA--------------KDKGDLVPLHNACSYGHYEV 259

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
            +LL+ +   +NA + W++ P+H A  K  +++  +L++
Sbjct: 260 TELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 298

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 22/78 (28%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
 Frame = +3

Query: 486 PIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CI 665
           P+HLA  + ++++ + L+ +  D+NA +K    P+H A   GH+D+A +L+       C+
Sbjct: 682 PLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNA---CV 738

Query: 666 YCGE---YQPIHFACRDG 710
              +   + P+H A + G
Sbjct: 739 NATDKWAFTPLHEAAQKG 756

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 13/52 (25%), Positives = 31/52 (59%)
 Frame = +3

Query: 486 PIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
           P+H+A +  H D+V++++ ++  +NA +      +H A   GH+   ++L++
Sbjct: 403 PLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLS 454

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 23/97 (23%), Positives = 42/97 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH+ACS G   + ++L+ +   ++   +              +   P+H A   G  +I
Sbjct: 562 PLHNACSYGHYEVAELLVKHGAVVNVADL--------------WKFTPLHEAAAKGKYEI 607

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKIL 635
            KLL+ +  D    N+    P+   ++ G  DI  +L
Sbjct: 608 CKLLLQHGADPTKKNRDGNTPLD-LVKDGDTDIQDLL 643

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 14/39 (35%), Positives = 22/39 (56%)
 Frame = +3

Query: 522 IVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           I +LL+    +IN   K    P+H A EK H D+ +++V
Sbjct: 382 ICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVV 420
>sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin R)
          Length = 1881

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 36/126 (28%), Positives = 58/126 (46%)
 Frame = +3

Query: 345  PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
            PLH     G + +  VLI +   +D+                  G  P+H+A  +G+I +
Sbjct: 671  PLHLVAQEGHVPVADVLIKHGVMVDAT--------------TRMGYTPLHVASHYGNIKL 716

Query: 525  VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            VK L+ ++ D+NA  K  Y P+H A ++GH DI  +L+        +      P+  A R
Sbjct: 717  VKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKR 776

Query: 705  DGYIDI 722
             GYI +
Sbjct: 777  LGYISV 782

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 38/141 (26%), Positives = 63/141 (44%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH AC    + ++++L+     ID+V                 G  P+H+A   GH+ I
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAV--------------TESGLTPLHVASFMGHLPI 419

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           VK L+      N SN     P+H A   GH ++AK L+  +         +  P+H A R
Sbjct: 420 VKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAAR 479

Query: 705 DGYIDIFENID*NKCDINAST 767
            G+ ++ + +  N  + N +T
Sbjct: 480 IGHTNMVKLLLENNANPNLAT 500

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 32/128 (25%), Positives = 59/128 (46%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G   + K L+ N  ++++                     P+H A + GH ++
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNA--------------KAKDDQTPLHCAARIGHTNM 485

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           VKLL++N  + N +    + P+H A  +GH++    L+ K+    C+    + P+H A +
Sbjct: 486 VKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAK 545

Query: 705 DGYIDIFE 728
            G + + E
Sbjct: 546 YGKVRVAE 553

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 29/97 (29%), Positives = 51/97 (52%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+HLA + GH ++V LL+  + + N  NK    P+H   ++GH+ +A +L+   +  
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENID*NKCDINAST 767
                  Y P+H A   G I + + +  ++ D+NA T
Sbjct: 695 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 36/142 (25%), Positives = 63/142 (44%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A  NG + + ++L+ +   I +                  G  PIH+A +  H+D 
Sbjct: 275 PLHCAARNGHVRISEILLDHGAPIQA--------------KTKNGLSPIHMAAQGDHLDC 320

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           V+LL+    +I+        P+H A   GH  +AK+L+ K           + P+H AC+
Sbjct: 321 VRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACK 380

Query: 705 DGYIDIFENID*NKCDINASTD 770
             ++ + E +      I+A T+
Sbjct: 381 KNHVRVMELLLKTGASIDAVTE 402

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 37/139 (26%), Positives = 61/139 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G   + KVL+    + +S                  G  P+H+ACK  H+ +
Sbjct: 341 PLHVAAHCGHHRVAKVLLDKGAKPNS--------------RALNGFTPLHIACKKNHVRV 386

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           ++LL+     I+A  +    P+H A   GH+ I K L+ +             P+H A R
Sbjct: 387 MELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAAR 446

Query: 705 DGYIDIFENID*NKCDINA 761
            G+ ++ + +  NK  +NA
Sbjct: 447 AGHTEVAKYLLQNKAKVNA 465

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/123 (25%), Positives = 53/123 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G + +V++L+    +I++                     P+H A + GH+ I
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIET--------------KTKDELTPLHCAARNGHVRI 287

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            ++L+D+   I A  K    PIH A +  H+D  ++L+        I      P+H A  
Sbjct: 288 SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAH 347

Query: 705 DGY 713
            G+
Sbjct: 348 CGH 350

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 22/86 (25%), Positives = 45/86 (52%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A K+G + + +LL++     NA+ K    P+H A+   ++DI K+L+ +    
Sbjct: 536 GFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP 595

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENI 734
                  Y P+H A +   +++  ++
Sbjct: 596 HSPAWNGYTPLHIAAKQNQVEVARSL 621

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 24/81 (29%), Positives = 41/81 (50%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A + G++ +V+LL+D    I    K +  P+H A   GH+ I++IL+      
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298

Query: 657 *CIYCGEYQPIHFACRDGYID 719
                    PIH A +  ++D
Sbjct: 299 QAKTKNGLSPIHMAAQGDHLD 319

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/126 (23%), Positives = 53/126 (42%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G   +VK+L+ N+   +                   G  P+H+A + GH++ 
Sbjct: 473 PLHCAARIGHTNMVKLLLENNANPNLA--------------TTAGHTPLHIAAREGHVET 518

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           V  L++ +       K  + P+H A + G + +A++L+ +             P+H A  
Sbjct: 519 VLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVH 578

Query: 705 DGYIDI 722
              +DI
Sbjct: 579 HNNLDI 584

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 23/97 (23%), Positives = 51/97 (52%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A  + ++++ +LL++    +N + +    P+H A  +G++ + ++L+ +    
Sbjct: 206 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 265

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENID*NKCDINAST 767
                 E  P+H A R+G++ I E +  +   I A T
Sbjct: 266 ETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 302

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 29/141 (20%), Positives = 62/141 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A  +  + +VK+L+       S                  G  P+H+A K   +++
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHS--------------PAWNGYTPLHIAAKQNQVEV 617

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            + L+      NA +     P+H A ++GH ++  +L++KQ            P+H   +
Sbjct: 618 ARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQ 677

Query: 705 DGYIDIFENID*NKCDINAST 767
           +G++ + + +  +   ++A+T
Sbjct: 678 EGHVPVADVLIKHGVMVDATT 698

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/99 (28%), Positives = 43/99 (43%)
 Frame = +3

Query: 339 WRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHI 518
           + PLH A   G I LVK L+ +  ++++                  G  P+H A + GH 
Sbjct: 702 YTPLHVASHYGNIKLVKFLLQHQADVNA--------------KTKLGYSPLHQAAQQGHT 747

Query: 519 DIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKIL 635
           DIV LL+ N    N  +     P+  A   G+I +  +L
Sbjct: 748 DIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 15/54 (27%), Positives = 34/54 (62%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           G  P+++A +  H+++VK L++N  + N + +  + P+  AL++GH ++   L+
Sbjct: 111 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 164

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 13/54 (24%), Positives = 33/54 (61%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           G   +H+A   G  ++V+ L++   ++NA ++  + P++ A ++ H+++ K L+
Sbjct: 78  GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLL 131

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 20/98 (20%), Positives = 45/98 (45%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G   +HLA K GH+ +V  L+  +  +  + K     +H A   G  ++ + LV      
Sbjct: 45  GLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 104

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENID*NKCDINASTD 770
                  + P++ A ++ ++++ + +  N  + N +T+
Sbjct: 105 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATE 142
>sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin)
          Length = 1862

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 36/126 (28%), Positives = 58/126 (46%)
 Frame = +3

Query: 345  PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
            PLH     G + +  VLI +   +D+                  G  P+H+A  +G+I +
Sbjct: 667  PLHLVSQEGHVLVADVLIKHGVTVDAT--------------TRMGYTPLHVASHYGNIKL 712

Query: 525  VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            VK L+ ++ D+NA  K  Y P+H A ++GH DI  +L+        +      P+  A R
Sbjct: 713  VKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKR 772

Query: 705  DGYIDI 722
             GYI +
Sbjct: 773  LGYISV 778

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 39/141 (27%), Positives = 61/141 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH AC    I ++++L+     ID+V                 G  P+H+A   GH+ I
Sbjct: 370 PLHIACKKNHIRVMELLLKTGASIDAV--------------TESGLTPLHVASFMGHLPI 415

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           VK L+      N SN     P+H A   GH ++AK L+  +         +  P+H A R
Sbjct: 416 VKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAAR 475

Query: 705 DGYIDIFENID*NKCDINAST 767
            G+  + + +  N    N +T
Sbjct: 476 IGHTGMVKLLLENGASPNLAT 496

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 37/142 (26%), Positives = 63/142 (44%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A  NG + + ++L+ +   I +                  G  PIH+A +  H+D 
Sbjct: 271 PLHCAARNGHVRISEILLDHGAPIQA--------------KTKNGLSPIHMAAQGDHLDC 316

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           V+LL+    +I+        P+H A   GH  +AK+L+ K           + P+H AC+
Sbjct: 317 VRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACK 376

Query: 705 DGYIDIFENID*NKCDINASTD 770
             +I + E +      I+A T+
Sbjct: 377 KNHIRVMELLLKTGASIDAVTE 398

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 34/128 (26%), Positives = 57/128 (44%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G   + K L+ N  + ++                     P+H A + GH  +
Sbjct: 436 PLHMAARAGHTEVAKYLLQNKAKANA--------------KAKDDQTPLHCAARIGHTGM 481

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           VKLL++N    N +    + P+H A  +GH+D A  L+ K+    C+    + P+H A +
Sbjct: 482 VKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAK 541

Query: 705 DGYIDIFE 728
            G + + E
Sbjct: 542 YGKVRLAE 549

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 29/97 (29%), Positives = 51/97 (52%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+HLA + GH ++V LL+  + + N  NK    P+H   ++GH+ +A +L+   +  
Sbjct: 631 GVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTV 690

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENID*NKCDINAST 767
                  Y P+H A   G I + + +  ++ D+NA T
Sbjct: 691 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 727

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 19/158 (12%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*I-------------------VFSXXXXXXXXX 467
           P+H A     +  V++L+  + EID + +                   V           
Sbjct: 304 PIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 363

Query: 468 XXYGCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQ 647
              G  P+H+ACK  HI +++LL+     I+A  +    P+H A   GH+ I K L+ + 
Sbjct: 364 ALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG 423

Query: 648 M*Y*CIYCGEYQPIHFACRDGYIDIFENID*NKCDINA 761
                       P+H A R G+ ++ + +  NK   NA
Sbjct: 424 ASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANA 461

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 20/150 (13%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCE--------------------IDSV*IVFSXXXXXXXX 464
           PLH A   G  G+VK+L+ N                       +D+  +           
Sbjct: 469 PLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTA-LALLEKEASQAC 527

Query: 465 XXXYGCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAK 644
               G  P+H+A K+G + + +LL+++    NA+ K    P+H A+   ++DI K+L+ +
Sbjct: 528 MTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPR 587

Query: 645 QM*Y*CIYCGEYQPIHFACRDGYIDIFENI 734
                      Y P+H A +   I++  ++
Sbjct: 588 GGSPHSPAWNGYTPLHIAAKQNQIEVARSL 617

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 31/123 (25%), Positives = 53/123 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G + +V++L+    +I++                     P+H A + GH+ I
Sbjct: 238 PLHIASRRGNVIMVRLLLDRGAQIET--------------RTKDELTPLHCAARNGHVRI 283

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            ++L+D+   I A  K    PIH A +  H+D  ++L+        I      P+H A  
Sbjct: 284 SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAH 343

Query: 705 DGY 713
            G+
Sbjct: 344 CGH 346

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 24/81 (29%), Positives = 41/81 (50%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A + G++ +V+LL+D    I    K +  P+H A   GH+ I++IL+      
Sbjct: 235 GITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPI 294

Query: 657 *CIYCGEYQPIHFACRDGYID 719
                    PIH A +  ++D
Sbjct: 295 QAKTKNGLSPIHMAAQGDHLD 315

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 23/97 (23%), Positives = 51/97 (52%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A  + ++++ +LL++    +N + +    P+H A  +G++ + ++L+ +    
Sbjct: 202 GFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQI 261

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENID*NKCDINAST 767
                 E  P+H A R+G++ I E +  +   I A T
Sbjct: 262 ETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 298

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 30/141 (21%), Positives = 62/141 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A  +  + +VK+L+       S                  G  P+H+A K   I++
Sbjct: 568 PLHVAVHHNNLDIVKLLLPRGGSPHS--------------PAWNGYTPLHIAAKQNQIEV 613

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            + L+      NA +     P+H A ++GH ++  +L++KQ            P+H   +
Sbjct: 614 ARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQ 673

Query: 705 DGYIDIFENID*NKCDINAST 767
           +G++ + + +  +   ++A+T
Sbjct: 674 EGHVLVADVLIKHGVTVDATT 694

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/99 (28%), Positives = 43/99 (43%)
 Frame = +3

Query: 339 WRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHI 518
           + PLH A   G I LVK L+ +  ++++                  G  P+H A + GH 
Sbjct: 698 YTPLHVASHYGNIKLVKFLLQHQADVNA--------------KTKLGYSPLHQAAQQGHT 743

Query: 519 DIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKIL 635
           DIV LL+ N    N  +     P+  A   G+I +  +L
Sbjct: 744 DIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVL 782

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 15/54 (27%), Positives = 34/54 (62%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           G  P+++A +  H+++VK L++N  + N + +  + P+  AL++GH ++   L+
Sbjct: 107 GFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLI 160

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 13/54 (24%), Positives = 33/54 (61%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           G   +H+A   G  ++V+ L++   ++NA ++  + P++ A ++ H+++ K L+
Sbjct: 74  GNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLL 127

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 20/98 (20%), Positives = 45/98 (45%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G   +HLA K GH+ +V  L+  +  +  + K     +H A   G  ++ + LV      
Sbjct: 41  GLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANV 100

Query: 657 *CIYCGEYQPIHFACRDGYIDIFENID*NKCDINASTD 770
                  + P++ A ++ ++++ + +  N  + N +T+
Sbjct: 101 NAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATE 138
>sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G)
          Length = 4377

 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 36/143 (25%), Positives = 64/143 (44%)
 Frame = +3

Query: 339  WRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHI 518
            + PLH A    ++ +   L+    + ++V                 G   +HLA + GH+
Sbjct: 632  YTPLHIAAKKNQMDIATTLLEYGADANAV--------------TRQGIASVHLAAQEGHV 677

Query: 519  DIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFA 698
            D+V LL+    ++N SNK    P+H A ++  +++A++LV +           Y P+H  
Sbjct: 678  DMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVG 737

Query: 699  CRDGYIDIFENID*NKCDINAST 767
            C  G I I   +  +   +NA T
Sbjct: 738  CHYGNIKIVNFLLQHSAKVNAKT 760

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 33/130 (25%), Positives = 57/130 (43%)
 Frame = +3

Query: 345  PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
            PLH A    R+ + +VL++    +D+                  G  P+H+ C +G+I I
Sbjct: 700  PLHLAAQEDRVNVAEVLVNQGAHVDA--------------QTKMGYTPLHVGCHYGNIKI 745

Query: 525  VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            V  L+ +   +NA  K  Y P+H A ++GH  I  +L+        +       +  A R
Sbjct: 746  VNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARR 805

Query: 705  DGYIDIFENI 734
             GYI + + +
Sbjct: 806  LGYISVVDTL 815

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 36/141 (25%), Positives = 59/141 (41%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH AC   RI ++++L+ +   I +V                 G  PIH+A   GH++I
Sbjct: 403 PLHIACKKNRIKVMELLLKHGASIQAV--------------TESGLTPIHVAAFMGHVNI 448

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           V  L+ +    N +N      +H A   G  ++ + LV            +  P+H + R
Sbjct: 449 VSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISAR 508

Query: 705 DGYIDIFENID*NKCDINAST 767
            G  DI + +       NA+T
Sbjct: 509 LGKADIVQQLLQQGASPNAAT 529

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 37/175 (21%), Positives = 66/175 (37%), Gaps = 33/175 (18%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G   +VK+L+    +ID+                  G  P+H   + GH  +
Sbjct: 271 PLHVASKRGNANMVKLLLDRGAKIDA--------------KTRDGLTPLHCGARSGHEQV 316

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM------------*Y*CIY 668
           V++L+D    I +  K    P+H A +  H++  ++L+   +             +   +
Sbjct: 317 VEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAH 376

Query: 669 CGEYQ---------------------PIHFACRDGYIDIFENID*NKCDINASTD 770
           CG Y+                     P+H AC+   I + E +  +   I A T+
Sbjct: 377 CGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTE 431

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/144 (22%), Positives = 61/144 (42%)
 Frame = +3

Query: 333 KFWRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFG 512
           K + PLH A   G++ +  +L+      D+                  G  P+H+A  + 
Sbjct: 564 KGFTPLHVAAKYGKLEVANLLLQKSASPDAA--------------GKSGLTPLHVAAHYD 609

Query: 513 HIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIH 692
           +  +  LL+D     +A+ K  Y P+H A +K  +DIA  L+        +       +H
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 669

Query: 693 FACRDGYIDIFENID*NKCDINAS 764
            A ++G++D+   +     ++N S
Sbjct: 670 LAAQEGHVDMVSLLLGRNANVNLS 693

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 30/130 (23%), Positives = 56/130 (43%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A     +  V++L+ ++  +D V   +                 +H+A   GH  +
Sbjct: 337 PLHMATQGDHLNCVQLLLQHNVPVDDVTNDY--------------LTALHVAAHCGHYKV 382

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
            K+L+D K + NA     + P+H A +K  I + ++L+        +      PIH A  
Sbjct: 383 AKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 442

Query: 705 DGYIDIFENI 734
            G+++I   +
Sbjct: 443 MGHVNIVSQL 452

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 22/97 (22%), Positives = 46/97 (47%)
 Frame = +3

Query: 348 LHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDIV 527
           LH A   G + +V  L+     +D+                  G   +H+A   G  ++V
Sbjct: 78  LHLASKEGHVEVVSELLQREANVDAA--------------TKKGNTALHIASLAGQAEVV 123

Query: 528 KLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           K+L+ N  ++NA ++  + P++ A ++ H+++ K L+
Sbjct: 124 KVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLL 160

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 24/97 (24%), Positives = 49/97 (50%)
 Frame = +3

Query: 348 LHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDIV 527
           LH A   G+  +VKVL++N   +++                  G  P+++A +  H+++V
Sbjct: 111 LHIASLAGQAEVVKVLVTNGANVNA--------------QSQNGFTPLYMAAQENHLEVV 156

Query: 528 KLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           K L+DN    + + +  + P+  AL++GH  +  +L+
Sbjct: 157 KFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 27/125 (21%), Positives = 55/125 (44%)
 Frame = +3

Query: 348 LHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDIV 527
           LH A  +G+  +V+ L+ +  ++++                     P+H++ + G  DIV
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEA--------------KAKDDQTPLHISARLGKADIV 515

Query: 528 KLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACRD 707
           + L+      NA+    Y P+H +  +GH D+A  L+             + P+H A + 
Sbjct: 516 QQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKY 575

Query: 708 GYIDI 722
           G +++
Sbjct: 576 GKLEV 580

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 17/56 (30%), Positives = 34/56 (60%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAK 644
           G  P+HL+ + GH D+   L+D+   ++ + K  + P+H A + G +++A +L+ K
Sbjct: 532 GYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQK 587

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 19/82 (23%), Positives = 42/82 (51%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G   +HLA K GH+++V  L+  + +++A+ K     +H A   G  ++ K+LV      
Sbjct: 74  GLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133

Query: 657 *CIYCGEYQPIHFACRDGYIDI 722
                  + P++ A ++ ++++
Sbjct: 134 NAQSQNGFTPLYMAAQENHLEV 155

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 28/125 (22%), Positives = 52/125 (41%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   G I +  +L++    +D                      P+H+A K G+ ++
Sbjct: 238 PLHIAAHYGNINVATLLLNRAAAVDFT--------------ARNDITPLHVASKRGNANM 283

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFACR 704
           VKLL+D    I+A  +    P+H     GH  + ++L+ +             P+H A +
Sbjct: 284 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQ 343

Query: 705 DGYID 719
             +++
Sbjct: 344 GDHLN 348

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 19/84 (22%), Positives = 43/84 (51%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A  +G+I++  LL++    ++ + +    P+H A ++G+ ++ K+L+ +    
Sbjct: 235 GFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294

Query: 657 *CIYCGEYQPIHFACRDGYIDIFE 728
                    P+H   R G+  + E
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVE 318

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 20/90 (22%), Positives = 41/90 (45%)
 Frame = +3

Query: 498 ACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGE 677
           A + GH++     I N  DIN  N+     +H A ++GH+++   L+ ++          
Sbjct: 48  AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107

Query: 678 YQPIHFACRDGYIDIFENID*NKCDINAST 767
              +H A   G  ++ + +  N  ++NA +
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQS 137

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 20/93 (21%), Positives = 43/93 (46%)
 Frame = +3

Query: 489 IHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIY 668
           +H+A +        LL+ N  + +  +K  + P+H A   G+I++A +L+ +        
Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265

Query: 669 CGEYQPIHFACRDGYIDIFENID*NKCDINAST 767
             +  P+H A + G  ++ + +      I+A T
Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKT 298
>sp|O95271|TNKS1_HUMAN Tankyrase 1 (TANK1) (Tankyrase I) (TNKS-1) (TRF1-interacting
           ankyrin-related ADP-ribose polymerase)
          Length = 1327

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 27/98 (27%), Positives = 50/98 (51%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A    R+ +V+ L+ +  ++ +                  G  P+H AC +GH ++
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVHA--------------KDKGGLVPLHNACSYGHYEV 732

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
            +LL+ +   +N ++ WK+ P+H A  KG  +I K+L+
Sbjct: 733 AELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLL 770

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 32/98 (32%), Positives = 46/98 (46%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A   GR  +V+ L+     + +                  G  P+H AC FGH ++
Sbjct: 219 PLHFAAGFGRKDVVEHLLQMGANVHA--------------RDDGGLIPLHNACSFGHAEV 264

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILV 638
           V LL+    D NA + W Y P+H A  KG ID+  +L+
Sbjct: 265 VSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 302

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 24/99 (24%), Positives = 51/99 (51%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A    R+ +V++L+ +  ++ +                  G  P+H AC +GH ++
Sbjct: 372 PLHLAAGYNRVRIVQLLLQHGADVHA--------------KDKGGLVPLHNACSYGHYEV 417

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
            +LL+ +   +NA + W++ P+H A  K  +++  +L++
Sbjct: 418 TELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 456

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 22/55 (40%), Positives = 34/55 (61%)
 Frame = +3

Query: 477  GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
            G  P+H A  +GH+DI  LLI     +NA++KW + P+H A +KG   +  +L+A
Sbjct: 870  GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLA 924

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
 Frame = +3

Query: 486  PIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CI 665
            P+HLA  + ++++ + L+++  D+NA +K    P+H A   GH+DIA +L+       C+
Sbjct: 840  PLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNT---CV 896

Query: 666  YCGE---YQPIHFACRDG 710
               +   + P+H A + G
Sbjct: 897  NATDKWAFTPLHEAAQKG 914

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/127 (24%), Positives = 49/127 (38%)
 Frame = +3

Query: 342 RPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHID 521
           R L  AC NG +  VK L+                             P+H A  FG  D
Sbjct: 184 RELLEACRNGDVSRVKRLVD-------------AANVNAKDMAGRKSSPLHFAAGFGRKD 230

Query: 522 IVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFAC 701
           +V+ L+    +++A +     P+H A   GH ++  +L+ +           Y P+H A 
Sbjct: 231 VVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAA 290

Query: 702 RDGYIDI 722
             G ID+
Sbjct: 291 IKGKIDV 297

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 23/97 (23%), Positives = 43/97 (44%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH+ACS G   + ++L+ +   ++   +              +   P+H A   G  +I
Sbjct: 720 PLHNACSYGHYEVAELLVRHGASVNVADL--------------WKFTPLHEAAAKGKYEI 765

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKIL 635
            KLL+ +  D    N+    P+   +++G  DI  +L
Sbjct: 766 CKLLLKHGADPTKKNRDGNTPLD-LVKEGDTDIQDLL 801
>sp|P57078|RIPK4_HUMAN Serine/threonine-protein kinase RIPK4 (Receptor-interacting
            serine/threonine-protein kinase 4) (Ankyrin repeat domain
            protein 3) (PKC-delta-interacting protein kinase)
          Length = 832

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 37/141 (26%), Positives = 61/141 (43%)
 Frame = +3

Query: 339  WRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHI 518
            W PLH+A   G + +VK+L                           G  P+HLA + GH 
Sbjct: 619  WLPLHYAAWQGHLPIVKLLAKQ-------------PGVSVNAQTLDGRTPLHLAAQRGHY 665

Query: 519  DIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFA 698
             + ++LID   D+N  +     P+H A E GH   A++L+ +      +    Y  +H A
Sbjct: 666  RVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLA 725

Query: 699  CRDGYIDIFENID*NKCDINA 761
             R+G++   + +   K D+ A
Sbjct: 726  ARNGHLATVKLLVEEKADVLA 746

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 31/103 (30%), Positives = 51/103 (49%)
 Frame = +3

Query: 339 WRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHI 518
           W  LH A  NG     ++L+  +  ++ V                 G  P+H+AC+ G  
Sbjct: 553 WTALHFAAQNGDESSTRLLLEKNASVNEV--------------DFEGRTPMHVACQHGQE 598

Query: 519 DIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQ 647
           +IV++L+    D++   K  + P+HYA  +GH+ I K+L AKQ
Sbjct: 599 NIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL-AKQ 640

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 19/55 (34%), Positives = 30/55 (54%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
           G   +HLA + GH+  VKLL++ K D+ A        +H A   GH ++ + LV+
Sbjct: 718 GYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS 772

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 21/82 (25%), Positives = 42/82 (51%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G  P+H+A +     +V+LL+  K  +NA ++ ++  +H+A + G     ++L+ K    
Sbjct: 519 GSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASV 578

Query: 657 *CIYCGEYQPIHFACRDGYIDI 722
             +      P+H AC+ G  +I
Sbjct: 579 NEVDFEGRTPMHVACQHGQENI 600

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 21/78 (26%), Positives = 42/78 (53%)
 Frame = +3

Query: 477 GCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y 656
           G   +HLA + G  +  K L+ N  + N SN+    P+H A+E+    + ++L+A+++  
Sbjct: 486 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545

Query: 657 *CIYCGEYQPIHFACRDG 710
                 ++  +HFA ++G
Sbjct: 546 NAKDEDQWTALHFAAQNG 563
>sp|Q13418|ILK1_HUMAN Integrin-linked protein kinase 1 (ILK-1) (59 kDa
           serine/threonine-protein kinase) (p59ILK)
          Length = 452

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 36/99 (36%), Positives = 48/99 (48%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH AC  GR  +V++LI     I+ +                    P+HLA   GH DI
Sbjct: 37  PLHWACREGRSAVVEMLIMRGARINVM--------------NRGDDTPLHLAASHGHRDI 82

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
           V+ L+  K DINA N+    P+HYA   G   +A+ LVA
Sbjct: 83  VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVA 121

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/87 (29%), Positives = 43/87 (49%)
 Frame = +3

Query: 474 YGCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM* 653
           +G  P+H AC+ G   +V++LI     IN  N+    P+H A   GH DI + L+  +  
Sbjct: 33  HGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKAD 92

Query: 654 Y*CIYCGEYQPIHFACRDGYIDIFENI 734
              +      P+H+AC  G   + E++
Sbjct: 93  INAVNEHGNVPLHYACFWGQDQVAEDL 119

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = +3

Query: 489 IHLACKFGHIDIVKLLIDN-KCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CI 665
           I   C+ G+   V+L +DN + D+N  +   + P+H+A  +G   + ++L+ +      +
Sbjct: 4   IFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVM 63

Query: 666 YCGEYQPIHFACRDGYIDIFENID*NKCDINA 761
             G+  P+H A   G+ DI + +   K DINA
Sbjct: 64  NRGDDTPLHLAASHGHRDIVQKLLQYKADINA 95

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 22/85 (25%), Positives = 39/85 (45%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A S+G   +V+ L+    +I++V                +G  P+H AC +G   +
Sbjct: 70  PLHLAASHGHRDIVQKLLQYKADINAV--------------NEHGNVPLHYACFWGQDQV 115

Query: 525 VKLLIDNKCDINASNKWKYQPIHYA 599
            + L+ N   ++  NK+   P+  A
Sbjct: 116 AEDLVANGALVSICNKYGEMPVDKA 140
>sp|P57043|ILK2_HUMAN Integrin-linked protein kinase 2 (ILK-2)
          Length = 452

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 36/99 (36%), Positives = 48/99 (48%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH AC  GR  +V++LI     I+ +                    P+HLA   GH DI
Sbjct: 37  PLHWACREGRSAVVEMLIMRGARINVM--------------NRGDDTPLHLAASHGHRDI 82

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
           V+ L+  K DINA N+    P+HYA   G   +A+ LVA
Sbjct: 83  VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVA 121

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/87 (29%), Positives = 43/87 (49%)
 Frame = +3

Query: 474 YGCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM* 653
           +G  P+H AC+ G   +V++LI     IN  N+    P+H A   GH DI + L+  +  
Sbjct: 33  HGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKAD 92

Query: 654 Y*CIYCGEYQPIHFACRDGYIDIFENI 734
              +      P+H+AC  G   + E++
Sbjct: 93  INAVNEHGNVPLHYACFWGQDQVAEDL 119

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = +3

Query: 489 IHLACKFGHIDIVKLLIDN-KCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CI 665
           I   C+ G+   V+L +DN + D+N  +   + P+H+A  +G   + ++L+ +      +
Sbjct: 4   IFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVM 63

Query: 666 YCGEYQPIHFACRDGYIDIFENID*NKCDINA 761
             G+  P+H A   G+ DI + +   K DINA
Sbjct: 64  NRGDDTPLHLAASHGHRDIVQKLLQYKADINA 95

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 22/85 (25%), Positives = 39/85 (45%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A S+G   +V+ L+    +I++V                +G  P+H AC +G   +
Sbjct: 70  PLHLAASHGHRDIVQKLLQYKADINAV--------------NEHGNVPLHYACFWGQDQV 115

Query: 525 VKLLIDNKCDINASNKWKYQPIHYA 599
            + L+ N   ++  NK+   P+  A
Sbjct: 116 AEDLVANGALVSICNKYGEMPVDKA 140
>sp|P57044|ILK_CAVPO Integrin-linked protein kinase (Beta-integrin-linked kinase)
          Length = 451

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 36/99 (36%), Positives = 48/99 (48%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH AC  GR  +V++LI     I+ +                    P+HLA   GH DI
Sbjct: 37  PLHWACREGRSAVVEMLIMRGARINVM--------------NRGDDTPLHLAASHGHRDI 82

Query: 525 VKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVA 641
           V+ L+  K DINA N+    P+HYA   G   +A+ LVA
Sbjct: 83  VQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVA 121

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/87 (29%), Positives = 43/87 (49%)
 Frame = +3

Query: 474 YGCQPIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM* 653
           +G  P+H AC+ G   +V++LI     IN  N+    P+H A   GH DI + L+  +  
Sbjct: 33  HGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKAD 92

Query: 654 Y*CIYCGEYQPIHFACRDGYIDIFENI 734
              +      P+H+AC  G   + E++
Sbjct: 93  INAVNEHGNVPLHYACFWGQDQVAEDL 119

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
 Frame = +3

Query: 489 IHLACKFGHIDIVKLLIDN-KCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CI 665
           I   C+ G+   V+L +DN + D+N  +   + P+H+A  +G   + ++L+ +      +
Sbjct: 4   IFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVM 63

Query: 666 YCGEYQPIHFACRDGYIDIFENID*NKCDINA 761
             G+  P+H A   G+ DI + +   K DINA
Sbjct: 64  NRGDDTPLHLAASHGHRDIVQKLLQYKADINA 95

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 22/85 (25%), Positives = 39/85 (45%)
 Frame = +3

Query: 345 PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
           PLH A S+G   +V+ L+    +I++V                +G  P+H AC +G   +
Sbjct: 70  PLHLAASHGHRDIVQKLLQYKADINAV--------------NEHGNVPLHYACFWGQDQV 115

Query: 525 VKLLIDNKCDINASNKWKYQPIHYA 599
            + L+ N   ++  NK+   P+  A
Sbjct: 116 AEDLVANGALVSICNKYGEMPMDKA 140
>sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (Histone
            H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic
            histone-lysine N-methyltransferase 1) (Eu-HMTase1)
            (G9a-like protein 1) (GLP1)
          Length = 1267

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 1/140 (0%)
 Frame = +3

Query: 345  PLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHIDI 524
            PL  A  N  +  VK LI     +D                   G   +HLA K GH ++
Sbjct: 778  PLMEAAENNHLEAVKYLIKAGALVDP--------------KDAEGSTCLHLAAKKGHYEV 823

Query: 525  VKLLIDN-KCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIHFAC 701
            V+ L+ N + D+N  +   + P+ +A E  H+D+ K+L++K          E   +H+A 
Sbjct: 824  VQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAA 883

Query: 702  RDGYIDIFENID*NKCDINA 761
              G +DI E +   KCD++A
Sbjct: 884  FSGCVDIAEILLAAKCDLHA 903

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 5/129 (3%)
 Frame = +3

Query: 348  LHHACSNGRIGLVKVLISN-----HCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFG 512
            LH A   G   +V+ L+SN     +C+ D                   G  P+  A ++ 
Sbjct: 812  LHLAAKKGHYEVVQYLLSNGQMDVNCQDDG------------------GWTPMIWATEYK 853

Query: 513  HIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CIYCGEYQPIH 692
            H+D+VKLL+    DIN  +  +   +H+A   G +DIA+IL+A +     +      P+H
Sbjct: 854  HVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLH 913

Query: 693  FACRDGYID 719
             A R+   D
Sbjct: 914  IAARENRYD 922

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
 Frame = +3

Query: 486  PIHLACKFGHIDIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAKQM*Y*CI 665
            P+H A + GH+DI  +L+    +I+  ++ +  P+  A E  H++  K L+         
Sbjct: 745  PLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPK 804

Query: 666  YCGEYQPIHFACRDGYIDIFENID*N-KCDINASTD 770
                   +H A + G+ ++ + +  N + D+N   D
Sbjct: 805  DAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDD 840

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/102 (24%), Positives = 44/102 (43%)
 Frame = +3

Query: 339  WRPLHHACSNGRIGLVKVLISNHCEIDSV*IVFSXXXXXXXXXXXYGCQPIHLACKFGHI 518
            W P+  A     + LVK+L+S   +I+                    C  +H A   G +
Sbjct: 843  WTPMIWATEYKHVDLVKLLLSKGSDIN------------IRDNEENIC--LHWAAFSGCV 888

Query: 519  DIVKLLIDNKCDINASNKWKYQPIHYALEKGHIDIAKILVAK 644
            DI ++L+  KCD++A N     P+H A  +   D   + +++
Sbjct: 889  DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 930

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
 Frame = +3

Query: 489 IHLACKFGHIDIVKLLIDNKCDIN--ASNKWKYQPIHYALEKGHIDIAKILV 638
           ++ + + G +  V L++ +  D N    ++ K  P+H A E GH+DI  +LV
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLV 762
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,003,372
Number of Sequences: 369166
Number of extensions: 1222574
Number of successful extensions: 4382
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3131
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4055
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)