Planaria EST Database


DrC_01618

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01618
         (909 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O60347|TBC12_HUMAN  TBC1 domain family member 12               216   7e-56
sp|Q8CGA2|TBC14_MOUSE  TBC1 domain family member 14               181   3e-45
sp|Q9P2M4|TBC14_HUMAN  TBC1 domain family member 14               180   4e-45
sp|Q80XC3|US6NL_MOUSE  USP6 N-terminal-like protein                87   8e-17
sp|Q92738|US6NL_HUMAN  USP6 N-terminal-like protein (Related...    86   1e-16
sp|Q09844|YAE3_SCHPO  Hypothetical protein C23D3.03c in chro...    83   9e-16
sp|Q9BXI6|TBC10_HUMAN  TBC1 domain family member 10A (EBP50-...    82   2e-15
sp|P58802|TBC10_MOUSE  TBC1 domain family member 10A (EBP50-...    81   5e-15
sp|Q9BYX2|TBCD2_HUMAN  TBC1 domain family member 2 (Prostate...    75   2e-13
sp|P53258|GYP2_YEAST  GTPase-activating protein GYP2 (MAC1-d...    70   8e-12
>sp|O60347|TBC12_HUMAN TBC1 domain family member 12
          Length = 769

 Score =  216 bits (550), Expect = 7e-56
 Identities = 117/295 (39%), Positives = 164/295 (55%)
 Frame = +3

Query: 24   VWRNFILPNWFHQQTSQYVRHLWWEGIPTSVRDKVWRQCIPNTLKLTKTHYDNFLSQMQE 203
            +W N ILPNW   ++++ VR LWW+G+P SVR KVW   + N L +T   Y+ FLS+ +E
Sbjct: 453  IWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKE 512

Query: 204  RIERYLEPVSQDDLATKATDKPNTEIDLNNRNGTHISPTVESKSSAAYDLYFTETVSIHN 383
            R + +                                    S++S+  D   TE VS+ +
Sbjct: 513  RWKSF------------------------------------SETSSEND---TEGVSVAD 533

Query: 384  KRSSSLSYXXXXXXXXXXXXXXDVDIRQILLNTIKLDVSRTFPHLNLFQDGGPHHDLLYQ 563
            + +S                          L  IKLD+SRTFP L +FQ GGP+HD+L+ 
Sbjct: 534  REAS--------------------------LELIKLDISRTFPSLYIFQKGGPYHDVLHS 567

Query: 564  LLGAYACYRPDIGYVQGMSFLAAVLILVMNVEDAFICFANILELPCHHAFYALDESEFTV 743
            +LGAY CYRPD+GYVQGMSF+AAVLIL +   DAFI FAN+L  PC  AF+ +D S    
Sbjct: 568  ILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLK 627

Query: 744  YLESFKLLLFTHLPQLAQHFIQHKLDVNIFLCDWLFTIYSRALPLETALRVWDIF 908
            Y  +F++    +L +L  HF  + L  +I+L DW+FT+YS++LPL+ A RVWD+F
Sbjct: 628  YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVF 682
>sp|Q8CGA2|TBC14_MOUSE TBC1 domain family member 14
          Length = 679

 Score =  181 bits (459), Expect = 3e-45
 Identities = 79/149 (53%), Positives = 111/149 (74%)
 Frame = +3

Query: 462 RQILLNTIKLDVSRTFPHLNLFQDGGPHHDLLYQLLGAYACYRPDIGYVQGMSFLAAVLI 641
           R+  L  IKLD+SRTFP+L +FQ GGP+HD+L+ +LGAY CYRPD+GYVQGMSF+AAVLI
Sbjct: 445 REASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLI 504

Query: 642 LVMNVEDAFICFANILELPCHHAFYALDESEFTVYLESFKLLLFTHLPQLAQHFIQHKLD 821
           L ++  DAFI F+N+L  PC  AF+ +D      Y  +F++    +LP+L  HF ++ L 
Sbjct: 505 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 564

Query: 822 VNIFLCDWLFTIYSRALPLETALRVWDIF 908
            +I+L DW+FT+YS++LPL+ A R+WD+F
Sbjct: 565 ADIYLIDWIFTLYSKSLPLDLACRIWDVF 593

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 30/60 (50%), Positives = 37/60 (61%)
 Frame = +3

Query: 27  WRNFILPNWFHQQTSQYVRHLWWEGIPTSVRDKVWRQCIPNTLKLTKTHYDNFLSQMQER 206
           W N ILPNW     S+ VR LWW+GIP SVR KVW   I N L +T   +D  L++ +ER
Sbjct: 363 WNNEILPNWETMWCSKKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKER 422
>sp|Q9P2M4|TBC14_HUMAN TBC1 domain family member 14
          Length = 678

 Score =  180 bits (457), Expect = 4e-45
 Identities = 79/149 (53%), Positives = 111/149 (74%)
 Frame = +3

Query: 462 RQILLNTIKLDVSRTFPHLNLFQDGGPHHDLLYQLLGAYACYRPDIGYVQGMSFLAAVLI 641
           R+  L  IKLD+SRTFP+L +FQ GGP+HD+L+ +LGAY CYRPD+GYVQGMSF+AAVLI
Sbjct: 444 REASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLI 503

Query: 642 LVMNVEDAFICFANILELPCHHAFYALDESEFTVYLESFKLLLFTHLPQLAQHFIQHKLD 821
           L ++  DAFI F+N+L  PC  AF+ +D      Y  +F++    +LP+L  HF ++ L 
Sbjct: 504 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 563

Query: 822 VNIFLCDWLFTIYSRALPLETALRVWDIF 908
            +I+L DW+FT+YS++LPL+ A R+WD+F
Sbjct: 564 PDIYLIDWIFTLYSKSLPLDLACRIWDVF 592

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 30/60 (50%), Positives = 37/60 (61%)
 Frame = +3

Query: 27  WRNFILPNWFHQQTSQYVRHLWWEGIPTSVRDKVWRQCIPNTLKLTKTHYDNFLSQMQER 206
           W N ILPNW     S+ VR LWW+GIP SVR KVW   I N L +T   +D  L++ +ER
Sbjct: 362 WNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKER 421
>sp|Q80XC3|US6NL_MOUSE USP6 N-terminal-like protein
          Length = 819

 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 51/154 (33%), Positives = 77/154 (50%), Gaps = 3/154 (1%)
 Frame = +3

Query: 456 DIRQILLNTIKLDVSRTFPHLNLFQDG-GPHHDLLYQLLGAYACYRPDIGYVQGMSFLAA 632
           DIRQI      LDV+RTF    +F+D  G     L+ +L AY+ Y  ++GY QGMS + A
Sbjct: 140 DIRQI-----DLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 194

Query: 633 VLILVMNVEDAFICFANILELPCH--HAFYALDESEFTVYLESFKLLLFTHLPQLAQHFI 806
           +L++ MN EDAF     +   P H  H F+     +   + E  + +L   L +L QH  
Sbjct: 195 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 254

Query: 807 QHKLDVNIFLCDWLFTIYSRALPLETALRVWDIF 908
             ++  + +   W F  +    P    LR+WDI+
Sbjct: 255 SQEIYTSFYTMKWFFQCFLDRTPFRLNLRIWDIY 288
>sp|Q92738|US6NL_HUMAN USP6 N-terminal-like protein (Related to the N terminus of tre)
           (RN-tre)
          Length = 828

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 51/154 (33%), Positives = 77/154 (50%), Gaps = 3/154 (1%)
 Frame = +3

Query: 456 DIRQILLNTIKLDVSRTFPHLNLFQDG-GPHHDLLYQLLGAYACYRPDIGYVQGMSFLAA 632
           DIRQI      LDV+RTF    +F+D  G     L+ +L AY+ Y  ++GY QGMS + A
Sbjct: 140 DIRQI-----DLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITA 194

Query: 633 VLILVMNVEDAFICFANILELPCH--HAFYALDESEFTVYLESFKLLLFTHLPQLAQHFI 806
           +L++ MN EDAF     +   P H  H F+     +   + E  + +L   L +L QH  
Sbjct: 195 LLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLD 254

Query: 807 QHKLDVNIFLCDWLFTIYSRALPLETALRVWDIF 908
             ++  + +   W F  +    P    LR+WDI+
Sbjct: 255 SQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIY 288
>sp|Q09844|YAE3_SCHPO Hypothetical protein C23D3.03c in chromosome I
          Length = 472

 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 51/143 (35%), Positives = 77/143 (53%), Gaps = 1/143 (0%)
 Frame = +3

Query: 483 IKLDVSRTFPHLNLFQDGGPHHDLLYQLLGAYACYRPDIGYVQGMSFLAAVLILVMNVED 662
           ++LD+  T PH +LF   GP    L  LL AY+ YR D  Y+ G SF+ A+L+L MN+  
Sbjct: 272 LELDLQSTMPHYSLFHTEGPLRRDLIGLLRAYSYYRFDTSYIPGTSFIGALLLLNMNLTS 331

Query: 663 AFICFANILELPCHHAFYALDESEFTVYLESFKLLLFTHLPQLAQH-FIQHKLDVNIFLC 839
           AF C AN+L+ P   A Y  D S    + ++F   L  + P+LA H  I+ +L  + F+ 
Sbjct: 332 AFNCLANLLDKPFLQAVYTQDTSSLKSFYQTFLDTLKKNEPELATHLLIKLELVPDDFVY 391

Query: 840 DWLFTIYSRALPLETALRVWDIF 908
             L  ++   +  E A R+ D +
Sbjct: 392 PLLRKLFIPMVSPEIASRILDCY 414

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 24/64 (37%), Positives = 33/64 (51%)
 Frame = +3

Query: 15  LTHVWRNFILPNWFHQQTSQYVRHLWWEGIPTSVRDKVWRQCIPNTLKLTKTHYDNFLSQ 194
           L +VW   IL NW     S     +W +GIP+ VR +VW + I N LKL    + N  + 
Sbjct: 187 LVNVWEREILRNWPDALKSSRYAGIWRQGIPSRVRGRVWEKAIGNNLKLDYQSFFNARAN 246

Query: 195 MQER 206
            Q+R
Sbjct: 247 AQKR 250
>sp|Q9BXI6|TBC10_HUMAN TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa)
           (EPI64 protein)
          Length = 508

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 51/148 (34%), Positives = 76/148 (51%), Gaps = 3/148 (2%)
 Frame = +3

Query: 474 LNTIKLDVSRTFPHLNLFQDGGPHHDL-LYQLLGAYACYRPDIGYVQGMSFLAAVLILVM 650
           L+ I+ D+ R FP   +F   G H    L+++L AY  YRP+ GY Q  + +AAVL++ M
Sbjct: 151 LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHM 210

Query: 651 NVEDAFICFANILE--LPCHHAFYALDESEFTVYLESFKLLLFTHLPQLAQHFIQHKLDV 824
             E AF C   I E  LP    +Y+       +  E    LL    P   +H  + K+D 
Sbjct: 211 PAEQAFWCLVQICEKYLP---GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDP 267

Query: 825 NIFLCDWLFTIYSRALPLETALRVWDIF 908
            +++ +W    +SR LP  + LRVWD+F
Sbjct: 268 LLYMTEWFMCAFSRTLPWSSVLRVWDMF 295
>sp|P58802|TBC10_MOUSE TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa)
           (EPI64 protein)
          Length = 500

 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 49/148 (33%), Positives = 76/148 (51%), Gaps = 3/148 (2%)
 Frame = +3

Query: 474 LNTIKLDVSRTFPHLNLFQDGGPHHDL-LYQLLGAYACYRPDIGYVQGMSFLAAVLILVM 650
           L+ I+ D+ R FP   +F   G H    L+++L AY  YRP+ GY Q  + +AAVL++ M
Sbjct: 151 LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHM 210

Query: 651 NVEDAFICFANILE--LPCHHAFYALDESEFTVYLESFKLLLFTHLPQLAQHFIQHKLDV 824
             E AF C   + E  LP    +Y+       +  E    LL    P   +H  + K+D 
Sbjct: 211 PAEQAFWCLVQVCEKYLP---GYYSEKLEAIQLDGEILFSLLQKVSPVAHKHLSRQKIDP 267

Query: 825 NIFLCDWLFTIYSRALPLETALRVWDIF 908
            +++ +W    ++R LP  + LRVWD+F
Sbjct: 268 LLYMTEWFMCAFARTLPWSSVLRVWDMF 295
>sp|Q9BYX2|TBCD2_HUMAN TBC1 domain family member 2 (Prostate antigen recognized and
            indentified by SEREX) (PARIS-1)
          Length = 917

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 48/144 (33%), Positives = 76/144 (52%), Gaps = 2/144 (1%)
 Frame = +3

Query: 483  IKLDVSRTFPHLNLFQ-DGGPHHDLLYQLLGAYACYRPDIGYVQGMSFLAAVLILVMNVE 659
            I+LD++RTFP+   F        D L ++L A++   P IGY QG++ LAA+ +LV+  E
Sbjct: 670  IELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEE 729

Query: 660  D-AFICFANILELPCHHAFYALDESEFTVYLESFKLLLFTHLPQLAQHFIQHKLDVNIFL 836
            + AF C   I+E      +Y    +   V     + LL   LP+L  H  QH +D+++  
Sbjct: 730  ESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAHLGQHHVDLSLVT 789

Query: 837  CDWLFTIYSRALPLETALRVWDIF 908
             +W   +++ +L     LRVWD F
Sbjct: 790  FNWFLVVFADSLISNILLRVWDAF 813
>sp|P53258|GYP2_YEAST GTPase-activating protein GYP2 (MAC1-dependent regulator) (MIC1
           protein)
          Length = 950

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 42/152 (27%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
 Frame = +3

Query: 474 LNTIKLDVSRTFPHLNLFQ-DGGPHHDLLYQLLGAYACYRPDIGYVQGMSFLAAVLILVM 650
           ++ I+ D+ R+ P  + +Q + G     L  +L AY+   PD+GY Q M+ + A  ++ M
Sbjct: 286 IDEIEKDLKRSLPEYSAYQTEEGIQR--LRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFM 343

Query: 651 NVEDAFICFANILEL--PCHHA--FYA--LDESEFTVYLESFKLLLFTHLPQLAQHFIQH 812
           + E AF C  N+ ++  P +++   Y   LD+  F  ++E         +P L ++ +QH
Sbjct: 344 SEEQAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVED-------RMPVLWEYILQH 396

Query: 813 KLDVNIFLCDWLFTIYSRALPLETALRVWDIF 908
            + +++    W  +++  ++PLE A+R+ DIF
Sbjct: 397 DIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIF 428
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,059,588
Number of Sequences: 369166
Number of extensions: 2051255
Number of successful extensions: 5131
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4923
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5096
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9222552960
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)