Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01605
(817 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WTP6|KAD2_MOUSE Adenylate kinase isoenzyme 2, mitochon... 279 6e-75
sp|P29410|KAD2_RAT Adenylate kinase isoenzyme 2, mitochondr... 278 1e-74
sp|P08166|KAD2_BOVIN Adenylate kinase isoenzyme 2, mitochon... 278 2e-74
sp|P54819|KAD2_HUMAN Adenylate kinase isoenzyme 2, mitochon... 276 5e-74
sp|P34346|KADX_CAEEL Probable adenylate kinase isoenzyme C2... 258 1e-68
sp|P33075|KAD1_SCHPO Adenylate kinase (ATP-AMP transphospho... 243 5e-64
sp|Q9HE76|KAD_NEUCR Probable adenylate kinase (ATP-AMP tran... 243 5e-64
sp|P07170|KAD1_YEAST Adenylate kinase cytosolic (ATP-AMP tr... 239 9e-63
sp|O82514|KAD1_ARATH Adenylate kinase 1 (ATP-AMP transphosp... 233 5e-61
sp|Q08480|KAD2_ORYSA Adenylate kinase B (ATP-AMP transphosp... 232 1e-60
>sp|Q9WTP6|KAD2_MOUSE Adenylate kinase isoenzyme 2, mitochondrial (ATP-AMP
transphosphorylase)
Length = 232
Score = 279 bits (714), Expect = 6e-75
Identities = 133/226 (58%), Positives = 174/226 (76%), Gaps = 2/226 (0%)
Frame = +2
Query: 50 NFFASESK--QNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQ 223
N ASE + + I A+L+GP G+GKGTQAPKL + + +CHLATGDMLRA+V+SGS LG++
Sbjct: 4 NVLASEPEIPKGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKK 63
Query: 224 VNEIMQQGGLISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKIN 403
+ M G L+SDE+V +LI+++L+ P CKNGFLLDGFPRTV QAE LD L+EKR K++
Sbjct: 64 LKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLD 123
Query: 404 AVVEFNVDDKVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETL 583
+V+EF++ D +L +RITGRL H SGRSYHEEFNPPK+ MKDD+TGE L+RR DDN + L
Sbjct: 124 SVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKAL 183
Query: 584 KSRLQSYRNDTSPLIGYYQKRNVHYQVKASQKPDKVFEDILTFFEK 721
K+RL++Y T+PL+ YY+KR +H + ASQ PD VF IL F K
Sbjct: 184 KTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDIVFASILAAFSK 229
>sp|P29410|KAD2_RAT Adenylate kinase isoenzyme 2, mitochondrial (ATP-AMP
transphosphorylase)
Length = 239
Score = 278 bits (711), Expect = 1e-74
Identities = 129/219 (58%), Positives = 170/219 (77%)
Frame = +2
Query: 65 ESKQNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQ 244
E + I A+L+GP G+GKGTQAPKL + + +CHLATGDMLRA+V+SGS LG+++ M
Sbjct: 11 EHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDA 70
Query: 245 GGLISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNV 424
G L+SDE+V +LI+++L+ P CKNGFLLDGFPRTV QAE LD L++KR K+++V+EF++
Sbjct: 71 GKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSI 130
Query: 425 DDKVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSY 604
D +L +RITGRL H SGRSYHEEFNPPK+ MKDD+TGE L+RR DDN + LK+RL++Y
Sbjct: 131 QDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAY 190
Query: 605 RNDTSPLIGYYQKRNVHYQVKASQKPDKVFEDILTFFEK 721
T+PL+ YY+KR +H + ASQ PD VF IL F K
Sbjct: 191 HTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSK 229
>sp|P08166|KAD2_BOVIN Adenylate kinase isoenzyme 2, mitochondrial (ATP-AMP
transphosphorylase)
Length = 241
Score = 278 bits (710), Expect = 2e-74
Identities = 130/219 (59%), Positives = 169/219 (77%)
Frame = +2
Query: 65 ESKQNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQ 244
ES + + A+L+GP G+GKGTQAPKL + + +CHLATGDMLRA+V+SGS LG+++ M
Sbjct: 13 ESPKGVRAVLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDA 72
Query: 245 GGLISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNV 424
G L+SDE+V +LI+++L+ P CKNGFLLDGFPRTV QAE LD L+EKR K+++V+EF++
Sbjct: 73 GKLVSDEMVLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSI 132
Query: 425 DDKVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSY 604
D +L +RITGRL H SGRSYHEEFNPPK+ MKDD+TGE L+RR DDN + LK RL++Y
Sbjct: 133 PDSLLIRRITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAY 192
Query: 605 RNDTSPLIGYYQKRNVHYQVKASQKPDKVFEDILTFFEK 721
T+PL+ YY KR +H + ASQ PD VF IL F K
Sbjct: 193 HTQTTPLVEYYSKRGIHSAIDASQTPDVVFASILAAFSK 231
>sp|P54819|KAD2_HUMAN Adenylate kinase isoenzyme 2, mitochondrial (ATP-AMP
transphosphorylase)
Length = 239
Score = 276 bits (706), Expect = 5e-74
Identities = 131/219 (59%), Positives = 169/219 (77%)
Frame = +2
Query: 65 ESKQNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQ 244
E + I A+L+GP G+GKGTQAP+L + + +CHLATGDMLRA+V+SGS LG+++ M
Sbjct: 11 EYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDA 70
Query: 245 GGLISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNV 424
G L+SDE+V +LI+++L+ P CKNGFLLDGFPRTV QAE LD L+EKR K+++V+EF++
Sbjct: 71 GKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSI 130
Query: 425 DDKVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSY 604
D +L +RITGRL H SGRSYHEEFNPPK+ MKDD+TGE L+RR DDN + LK RLQ+Y
Sbjct: 131 PDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAY 190
Query: 605 RNDTSPLIGYYQKRNVHYQVKASQKPDKVFEDILTFFEK 721
T+PLI YY+KR +H + ASQ PD VF IL F K
Sbjct: 191 HTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
>sp|P34346|KADX_CAEEL Probable adenylate kinase isoenzyme C29E4.8 (ATP-AMP
transphosphorylase)
Length = 251
Score = 258 bits (659), Expect = 1e-68
Identities = 127/216 (58%), Positives = 156/216 (72%)
Frame = +2
Query: 74 QNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGL 253
+ I AI IGP GSGKGTQAP Q+Y CHLATGD+LRA V+SGS G+++ M G L
Sbjct: 25 RGIRAIFIGPPGSGKGTQAPAFAQKYFSCHLATGDLLRAEVASGSEFGKELKATMDAGKL 84
Query: 254 ISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNVDDK 433
+SDE+VCKLI++ L+KPECK GF+LDGFPRT GQAEKLD +LE+R + ++ VVEFN+ D
Sbjct: 85 VSDEVVCKLIEQKLEKPECKYGFILDGFPRTSGQAEKLDEILERRKTPLDTVVEFNIADD 144
Query: 434 VLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSYRND 613
+L +RITGRLFH+ SGRSYH EF PPK MKDD+TGE L+RR DDN ETL+ RL Y
Sbjct: 145 LLVRRITGRLFHIASGRSYHLEFKPPKVPMKDDLTGEPLIRRSDDNEETLRKRLVQYHQM 204
Query: 614 TSPLIGYYQKRNVHYQVKASQKPDKVFEDILTFFEK 721
T PL+ YY+K VH V A++ V I F K
Sbjct: 205 TVPLVDYYKKHGVHVAVDAAKPMTDVKAHIDQVFAK 240
>sp|P33075|KAD1_SCHPO Adenylate kinase (ATP-AMP transphosphorylase)
Length = 220
Score = 243 bits (620), Expect = 5e-64
Identities = 119/212 (56%), Positives = 158/212 (74%), Gaps = 1/212 (0%)
Frame = +2
Query: 89 ILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEI 268
IL+GP G+GKGTQAP + ++Y I HLATGDMLR+ V+ + LG++ +IM QGGL+SD+I
Sbjct: 7 ILVGPPGAGKGTQAPNIQKKYGIAHLATGDMLRSQVARQTELGKEAKKIMDQGGLVSDDI 66
Query: 269 VCKLI-DESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNVDDKVLEQ 445
V +I DE L+ PECKNGF+LDGFPRTV QAEKL LL++ +N V+E VDD++L +
Sbjct: 67 VTGMIKDEILNNPECKNGFILDGFPRTVVQAEKLTALLDELKLDLNTVLELQVDDELLVR 126
Query: 446 RITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSYRNDTSPL 625
RITGRL H SGRSYH EFNPPK MKDDVTGE L++R DDN + L+ RL +Y T+P+
Sbjct: 127 RITGRLVHPGSGRSYHLEFNPPKVPMKDDVTGEPLIQRSDDNADALRKRLVTYHEQTTPV 186
Query: 626 IGYYQKRNVHYQVKASQKPDKVFEDILTFFEK 721
+ +Y+K+ V A+QKP++V+E I+ EK
Sbjct: 187 VEFYKKKGKWAAVDAAQKPEQVWEQIVAILEK 218
>sp|Q9HE76|KAD_NEUCR Probable adenylate kinase (ATP-AMP transphosphorylase)
Length = 236
Score = 243 bits (620), Expect = 5e-64
Identities = 114/211 (54%), Positives = 153/211 (72%), Gaps = 1/211 (0%)
Frame = +2
Query: 89 ILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGGLISDEI 268
+L+GP G+GKGTQAPK+ +++ CHLATGDMLRA V+ G+ LG+Q +IM +GGL+SD+I
Sbjct: 2 VLMGPPGAGKGTQAPKIKEKFNCCHLATGDMLRAQVAKGTALGKQAKKIMNEGGLVSDDI 61
Query: 269 VCKLIDESLDK-PECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNVDDKVLEQ 445
V +I + L+ EC+ GF+LDGFPRTV QAE LD +L +RN + VE +DD +L
Sbjct: 62 VIGMIKDELENNKECQGGFILDGFPRTVPQAEGLDAMLRERNLPLQHAVELKIDDSLLVA 121
Query: 446 RITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSYRNDTSPL 625
RITGRL H SGRSYH FNPPK MKDD+TGE LV+R DDN E L+ RL++Y T+P+
Sbjct: 122 RITGRLVHPASGRSYHRIFNPPKDDMKDDITGEPLVQRSDDNAEALRKRLETYHKQTAPV 181
Query: 626 IGYYQKRNVHYQVKASQKPDKVFEDILTFFE 718
+GYYQ + + ASQ+P +V++ +L FE
Sbjct: 182 VGYYQNTGIWKAIDASQEPAQVWKSLLAIFE 212
>sp|P07170|KAD1_YEAST Adenylate kinase cytosolic (ATP-AMP transphosphorylase)
Length = 222
Score = 239 bits (609), Expect = 9e-63
Identities = 115/214 (53%), Positives = 154/214 (71%), Gaps = 1/214 (0%)
Frame = +2
Query: 68 SKQNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQG 247
S ++I +LIGP G+GKGTQAP L +R+ HLATGDMLR+ ++ G+ LG + +IM QG
Sbjct: 3 SSESIRMVLIGPPGAGKGTQAPNLQERFHAAHLATGDMLRSQIAKGTQLGLEAKKIMDQG 62
Query: 248 GLISDEIVCKLI-DESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNV 424
GL+SD+I+ +I DE + P CKNGF+LDGFPRT+ QAEKLD +L+++ + + +E V
Sbjct: 63 GLVSDDIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKV 122
Query: 425 DDKVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSY 604
DD++L RITGRL H SGRSYH+ FNPPK+ MKDDVTGE LV+R DDN + LK RL +Y
Sbjct: 123 DDELLVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAY 182
Query: 605 RNDTSPLIGYYQKRNVHYQVKASQKPDKVFEDIL 706
T P++ +Y+K + V ASQ P V+ DIL
Sbjct: 183 HAQTEPIVDFYKKTGIWAGVDASQPPATVWADIL 216
>sp|O82514|KAD1_ARATH Adenylate kinase 1 (ATP-AMP transphosphorylase 1)
Length = 246
Score = 233 bits (594), Expect = 5e-61
Identities = 109/211 (51%), Positives = 155/211 (73%)
Frame = +2
Query: 71 KQNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQGG 250
K + I IGP GSGKGTQ+P + Y +CHL+TGDMLRA V+S +PLG + E M++G
Sbjct: 31 KPDKRLIFIGPPGSGKGTQSPVVKDEYCLCHLSTGDMLRAAVASKTPLGVKAKEAMEKGE 90
Query: 251 LISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNVDD 430
L+SD++V +IDE+++KP+C+ GF+LDGFPRTV QAEKLD +L++R ++I+ V+ F +DD
Sbjct: 91 LVSDDLVVGIIDEAMNKPKCQKGFILDGFPRTVTQAEKLDEMLKRRGTEIDKVLNFAIDD 150
Query: 431 KVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSYRN 610
+LE+RITGR H SGRSYH +F PPK DD+TGE L++RKDDN + LKSRL ++ +
Sbjct: 151 AILEERITGRWIHPSSGRSYHTKFAPPKTPGVDDITGEPLIQRKDDNADVLKSRLAAFHS 210
Query: 611 DTSPLIGYYQKRNVHYQVKASQKPDKVFEDI 703
T P+I YY K+ V ++A + P +V ++
Sbjct: 211 QTQPVIDYYAKKAVLTNIQAEKAPQEVTSEV 241
>sp|Q08480|KAD2_ORYSA Adenylate kinase B (ATP-AMP transphosphorylase)
Length = 243
Score = 232 bits (591), Expect = 1e-60
Identities = 110/212 (51%), Positives = 152/212 (71%)
Frame = +2
Query: 68 SKQNINAILIGPAGSGKGTQAPKLVQRYKICHLATGDMLRAIVSSGSPLGRQVNEIMQQG 247
SK + IL+GP GSGKGTQ+P + Y +CHLATGDMLRA V++ +PLG + E M +G
Sbjct: 27 SKPDKRLILVGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGVKAKEAMDKG 86
Query: 248 GLISDEIVCKLIDESLDKPECKNGFLLDGFPRTVGQAEKLDILLEKRNSKINAVVEFNVD 427
L+SD++V +IDE++ KP C+ GF+LDGFPRTV QA+KLD +LEK+ +K++ V+ F +D
Sbjct: 87 ELVSDDLVVGIIDEAMKKPSCQKGFILDGFPRTVVQAQKLDEMLEKKGTKVDKVLNFAID 146
Query: 428 DKVLEQRITGRLFHLPSGRSYHEEFNPPKQQMKDDVTGEQLVRRKDDNIETLKSRLQSYR 607
D +LE+RITGR H SGRSYH +F PPK DDVTGE L++RKDD E LKSRL+++
Sbjct: 147 DSILEERITGRWIHPSSGRSYHTKFAPPKVPGVDDVTGEPLIQRKDDTAEVLKSRLEAFH 206
Query: 608 NDTSPLIGYYQKRNVHYQVKASQKPDKVFEDI 703
T P+I YY K+ + + A + P +V ++
Sbjct: 207 KQTEPVIDYYSKKALVANLHAEKPPKEVTAEV 238
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,467,365
Number of Sequences: 369166
Number of extensions: 1702643
Number of successful extensions: 6458
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6025
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6212
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)