Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01574 (772 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P16354|PA23_HELSU Phospholipase A2 isozymes PA3A/PA3B/PA... 102 2e-21 sp|Q9BMK4|PA2_APICC Phospholipase A2 (Phosphatidylcholine 2... 97 4e-20 sp|Q7M4I5|PA2_APIDO Phospholipase A2 (Phosphatidylcholine 2... 97 5e-20 sp|P00630|PA2_APIME Phospholipase A2 precursor (Phosphatidy... 97 6e-20 sp|P80003|PA22_HELSU Phospholipase A2 isozymes PA2/PA4 (Pho... 92 2e-18 sp|Q9NZ20|PA2G3_HUMAN Group III secretory phospholipase A2 ... 91 3e-18 sp|Q6PXP0|PHLIP_ANUPH Phaiodactylipin precursor [Contains: ... 91 3e-18 sp|P82971|PA2_BOMTE Phospholipase A2 (Phosphatidylcholine 2... 90 8e-18 sp|Q7M4I6|PA2_MEGPE Phospholipase A2 (Phosphatidylcholine 2... 86 9e-17 sp|P59888|IPTXI_PANIM Imperatoxin I precursor (IpTxi) (Impe... 77 4e-14
>sp|P16354|PA23_HELSU Phospholipase A2 isozymes PA3A/PA3B/PA5 (Phosphatidylcholine 2-acylhydrolase) Length = 143 Score = 102 bits (253), Expect = 2e-21 Identities = 41/105 (39%), Positives = 65/105 (61%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I PGT WCG GN A++ + G E +TD CC DHD C N+I + E K +N + T+ C Sbjct: 4 IMPGTLWCGAGNAASDYSQLGTEKDTDMCCRDHDHCENWISALEYKHGMRNYYPSTISHC 63 Query: 444 GCDDEFYLCLKEVDNQASDKIGRLFFNMVRMECFKNEVINVCLSW 578 CD++F CL ++ + +D +G+ +FN++++ CF+ E C+ W Sbjct: 64 DCDNQFRSCLMKLKDGTADYVGQTYFNVLKIPCFELEEGEGCVDW 108
>sp|Q9BMK4|PA2_APICC Phospholipase A2 (Phosphatidylcholine 2-acylhydrolase) Length = 134 Score = 97.4 bits (241), Expect = 4e-20 Identities = 40/98 (40%), Positives = 61/98 (62%), Gaps = 1/98 (1%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I+PGT WCG GN+++ + G TD CC HD CP+ + +GE+K N+ +T + C Sbjct: 2 IYPGTLWCGHGNVSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSC 61 Query: 444 GCDDEFYLCLKEV-DNQASDKIGRLFFNMVRMECFKNE 554 CDD FY CLK D +S +G+++FN++ +C+K E Sbjct: 62 DCDDTFYDCLKNSGDKISSYFVGKMYFNLIDTKCYKLE 99
>sp|Q7M4I5|PA2_APIDO Phospholipase A2 (Phosphatidylcholine 2-acylhydrolase) Length = 134 Score = 97.1 bits (240), Expect = 5e-20 Identities = 40/98 (40%), Positives = 62/98 (63%), Gaps = 1/98 (1%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I+PGT WCG GN++++ + G TD CC HD CP+ + +GE+K N+ +T + C Sbjct: 2 IYPGTLWCGHGNVSSSPDELGRFKHTDSCCRSHDMCPDVMSAGESKHGLTNTASHTRLSC 61 Query: 444 GCDDEFYLCLK-EVDNQASDKIGRLFFNMVRMECFKNE 554 CDD+FY CLK D +S +G ++FN++ +C+K E Sbjct: 62 DCDDKFYDCLKNSSDTISSYFVGEMYFNILDTKCYKLE 99
>sp|P00630|PA2_APIME Phospholipase A2 precursor (Phosphatidylcholine 2-acylhydrolase) (Allergen Api m 1) (Api m I) Length = 167 Score = 96.7 bits (239), Expect = 6e-20 Identities = 40/98 (40%), Positives = 61/98 (62%), Gaps = 1/98 (1%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I+PGT WCG GN ++ + G TD CC HD CP+ + +GE+K N+ +T + C Sbjct: 35 IYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSC 94 Query: 444 GCDDEFYLCLK-EVDNQASDKIGRLFFNMVRMECFKNE 554 CDD+FY CLK D +S +G+++FN++ +C+K E Sbjct: 95 DCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLE 132
>sp|P80003|PA22_HELSU Phospholipase A2 isozymes PA2/PA4 (Phosphatidylcholine 2-acylhydrolase) Length = 142 Score = 91.7 bits (226), Expect = 2e-18 Identities = 38/103 (36%), Positives = 61/103 (59%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I PGT WCG GN A++ + G E +TD CC DHD C + + + E K +N +T+ C Sbjct: 4 IMPGTLWCGAGNAASDYSQLGTEKDTDMCCRDHDHCSDTMAALEYKHGMRNYRPHTVSHC 63 Query: 444 GCDDEFYLCLKEVDNQASDKIGRLFFNMVRMECFKNEVINVCL 572 CD++F CL V ++ +D +G +F ++++ CF+ E C+ Sbjct: 64 DCDNQFRSCLMNVKDRTADLVGMTYFTVLKISCFELEEGEGCV 106
>sp|Q9NZ20|PA2G3_HUMAN Group III secretory phospholipase A2 precursor (Phosphatidylcholine 2-acylhydrolase GIII) (GIII sPLA2) Length = 509 Score = 91.3 bits (225), Expect = 3e-18 Identities = 43/114 (37%), Positives = 60/114 (52%) Frame = +3 Query: 270 PGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDCGC 449 PGT WCG G+ A N ++ G D CC +HDRCP I + + +N +T+ C C Sbjct: 154 PGTLWCGVGDSAGNSSELGVFQGPDLCCREHDRCPQNISPLQYNYGIRNYRFHTISHCDC 213 Query: 450 DDEFYLCLKEVDNQASDKIGRLFFNMVRMECFKNEVINVCLSWYIPGVWCRKRG 611 D F CL+ + SD +G FFN++ + CF E C++WY G CR G Sbjct: 214 DTRFQQCLQNQHDSISDIVGVAFFNVLEIPCFVLEEQEACVAWYWWG-GCRMYG 266
>sp|Q6PXP0|PHLIP_ANUPH Phaiodactylipin precursor [Contains: Phaiodactylipin large subunit ; Phaiodactylipin small subunit] Length = 157 Score = 91.3 bits (225), Expect = 3e-18 Identities = 43/104 (41%), Positives = 60/104 (57%), Gaps = 9/104 (8%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I GTKWCG NIAAN +D G +E DKCC DHD C + I SGETK+ +N +T+++C Sbjct: 28 IVSGTKWCGNNNIAANYSDLGF-LEADKCCRDHDHCDH-IASGETKYGLENKGLFTILNC 85 Query: 444 GCDDEFYLCLKEVDNQ---------ASDKIGRLFFNMVRMECFK 548 CD+ F CLKE+ N ++ + R +F C++ Sbjct: 86 DCDEAFDHCLKEISNNVTTDIRQKGGAENVWRFYFQWYNANCYR 129
>sp|P82971|PA2_BOMTE Phospholipase A2 (Phosphatidylcholine 2-acylhydrolase) (Allergen Bom t 1) Length = 136 Score = 89.7 bits (221), Expect = 8e-18 Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 IFPGT WCG GN+A G ETD CC HD CP+ I + +K N+ YT + C Sbjct: 2 IFPGTLWCGNGNLANGTNQLGSWKETDSCCRTHDMCPDLIEAHGSKHGLTNAADYTRLSC 61 Query: 444 GCDDEFYLCL-KEVDNQASDKIGRLFFNMVRMECFK 548 CD+EF CL D ++ +GR +F ++ +CF+ Sbjct: 62 ECDEEFRRCLHNSGDTVSAGFVGRTYFTVLHTQCFR 97
>sp|Q7M4I6|PA2_MEGPE Phospholipase A2 (Phosphatidylcholine 2-acylhydrolase) Length = 136 Score = 86.3 bits (212), Expect = 9e-17 Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 1/96 (1%) Frame = +3 Query: 264 IFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLMDC 443 I+PGT WCG GNIA + G ETD CC HD CP+ I + +K N YT ++C Sbjct: 2 IYPGTLWCGNGNIANGTNELGLWKETDACCRTHDMCPDIIEAHGSKHGLTNPADYTRLNC 61 Query: 444 GCDDEFYLCLKEVDNQASDK-IGRLFFNMVRMECFK 548 CD+EF CL + S +GR +F ++ +CF+ Sbjct: 62 ECDEEFRHCLHNSGDAVSAAFVGRTYFTILGTQCFR 97
>sp|P59888|IPTXI_PANIM Imperatoxin I precursor (IpTxi) (Imperatoxin inhibitor) [Contains: Imperatoxin I large subunit ; Imperatoxin I small subunit] Length = 167 Score = 77.4 bits (189), Expect = 4e-14 Identities = 37/100 (37%), Positives = 54/100 (54%), Gaps = 4/100 (4%) Frame = +3 Query: 258 DRIFPGTKWCGPGNIAANETDFGEEIETDKCCHDHDRCPNFIRSGETKWNFKNSFKYTLM 437 D GTKWCG GN A + ++ G D CC HD C N I SG+TK+ N KYT+M Sbjct: 30 DETMWGTKWCGSGNEATDISELGYWSNLDSCCRTHDHCDN-IPSGQTKYGLTNEGKYTMM 88 Query: 438 DCGCDDEFYLCLKEV----DNQASDKIGRLFFNMVRMECF 545 +C C+ F CL+ V + A+ + + +F++ C+ Sbjct: 89 NCKCETAFEQCLRNVTGGMEGPAAGFVRKTYFDLYGNGCY 128
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,685,484 Number of Sequences: 369166 Number of extensions: 1815315 Number of successful extensions: 4636 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4494 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4622 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7163732800 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)