Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01543 (892 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P54886|P5CS_HUMAN Delta 1-pyrroline-5-carboxylate synthe... 243 5e-64 sp|Q9Z110|P5CS_MOUSE Delta 1-pyrroline-5-carboxylate synthe... 243 7e-64 sp|P54889|P5CS_CAEEL Probable delta 1-pyrroline-5-carboxyla... 227 4e-59 sp|O65361|P5CS_MESCR Delta 1-pyrroline-5-carboxylate synthe... 187 3e-47 sp|O04226|P5CS_ORYSA Delta 1-pyrroline-5-carboxylate synthe... 184 2e-46 sp|O04015|P5CS_ACTCH Delta 1-pyrroline-5-carboxylate synthe... 183 5e-46 sp|Q96480|P5CS_LYCES Delta 1-pyrroline-5-carboxylate synthe... 180 4e-45 sp|P32296|P5CS_VIGAC Delta 1-pyrroline-5-carboxylate synthe... 180 5e-45 sp|P54887|P5CS1_ARATH Delta 1-pyrroline-5-carboxylate synth... 180 5e-45 sp|P54888|P5CS2_ARATH Delta 1-pyrroline-5-carboxylate synth... 176 1e-43
>sp|P54886|P5CS_HUMAN Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 795 Score = 243 bits (620), Expect = 5e-64 Identities = 142/296 (47%), Positives = 187/296 (63%), Gaps = 4/296 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP + + LID + S V FG KSRVG GGME+K KAA WAL G SVVI GTH Sbjct: 275 PPGSDDAKLIDIFYPGDQQS-VTFGTKSRVGMGGMEAKVKAALWALQGGTSVVIANGTHP 333 Query: 197 ----NALLEIMHGKKVGTFFTLTPQEDNQVELQAELARKASLELFQSTSNQRANAIRKLA 364 + + +I+ GKKVGTFF+ VE Q E+AR L QRA I LA Sbjct: 334 KVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIIHHLA 393 Query: 365 DLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLNR 544 DLL +Q++EIL+AN +D A+ L + QIA S + + R Sbjct: 394 DLLTDQRDEILLANKKDLEEAEGRLAAPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGR 453 Query: 545 VLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNSN 724 VLR+T ++ NL L+++T+PIGVLLVIFESRPDCLPQVA+LAIASGNG+LLKGG EA +SN Sbjct: 454 VLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSN 513 Query: 725 KYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 + L L ++AL G+ +AV LV+ RE++++L +L+K IDL+IPRGSSQ++ I+ Sbjct: 514 RILHLLTQEALSIHGV-KEAVQLVNTREEVEDLCRLDKMIDLIIPRGSSQLVRDIQ 568
>sp|Q9Z110|P5CS_MOUSE Delta 1-pyrroline-5-carboxylate synthetase (P5CS) (Aldehyde dehydrogenase 18 family member A1) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 795 Score = 243 bits (619), Expect = 7e-64 Identities = 141/296 (47%), Positives = 185/296 (62%), Gaps = 4/296 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP + + LID + S V FG KSRVG GGME+K KAA WAL G SVVI GTH Sbjct: 275 PPGSDDAKLIDIFYPGDQQS-VTFGTKSRVGLGGMEAKVKAALWALQGGTSVVIANGTHP 333 Query: 197 ----NALLEIMHGKKVGTFFTLTPQEDNQVELQAELARKASLELFQSTSNQRANAIRKLA 364 + + +I+ GKKVGTFF+ VE Q E+AR L QRA I LA Sbjct: 334 KVSGHVITDIVEGKKVGTFFSEVKPAGPTVEQQGEMARSGGRMLATLEPEQRAEIINHLA 393 Query: 365 DLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLNR 544 DLL +Q+ EIL+AN +D A+ L + QIA S + R Sbjct: 394 DLLTDQREEILLANKKDLEEAEGRLASPLLKRLSLSTSKLNSLAIGLRQIAASSQESVGR 453 Query: 545 VLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNSN 724 VLR+T ++ NL L+++T+PIGVLLVIFESRPDCLPQVA+LAIASGNG+LLKGG EA +SN Sbjct: 454 VLRRTRIAKNLELEQVTVPIGVLLVIFESRPDCLPQVAALAIASGNGLLLKGGKEAAHSN 513 Query: 725 KYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 + L L ++AL G+ +A+ LV+ RE++++L +L+K IDL+IPRGSSQ++ I+ Sbjct: 514 RILHLLTQEALSIHGV-KEAIQLVNTREEVEDLCRLDKIIDLIIPRGSSQLVRDIQ 568
>sp|P54889|P5CS_CAEEL Probable delta 1-pyrroline-5-carboxylate synthetase (P5CS) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 800 Score = 227 bits (578), Expect = 4e-59 Identities = 134/295 (45%), Positives = 180/295 (61%), Gaps = 3/295 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP+ EGS L+ TY + NS V FG S+ GTGGMESK A AL G++ VI G + Sbjct: 269 PPDLEGSRLLYTYVPSE-NSGVTFGANSKFGTGGMESKVTACVNALNNGVTTVITNGLAQ 327 Query: 197 NALLEIMHGKKVGTFFTLTP-QEDNQVELQAELARKASLELFQSTSNQRANAIRKLADLL 373 +A+ + + GKK+GT F T E +E AE R A +L ++ +R +R LA LL Sbjct: 328 DAITDAVAGKKIGTMFCNTKGYEGPPIEEVAEKCRDAGRQLAALSNKERGAMVRHLAALL 387 Query: 374 IEQQNEILIANDEDFRLAKY-DLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLNRVL 550 ++++ I+ AN D AK LD + N IADS L+ RVL Sbjct: 388 VDKEKYIIEANQTDLANAKSAGLDPQLLNRLKMTPEKIQDLHAGLNTIADSAETLVGRVL 447 Query: 551 RKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNSNKY 730 +K ++S+ L L+++T+PIG L+VIFESRPDCLPQVASLA+ASGN +LLKGG EA SNK Sbjct: 448 KKVKISEGLFLEQVTVPIGSLMVIFESRPDCLPQVASLAMASGNALLLKGGKEAEESNKA 507 Query: 731 LFKLVKQALESQGLN-SDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 L LV++AL + G DAV LV RED+ +LLQL IDL+IPRGSS ++ ++ Sbjct: 508 LHALVQEALGTHGFEMRDAVTLVRSREDVADLLQLKDLIDLIIPRGSSDLVRSMQ 562
>sp|O65361|P5CS_MESCR Delta 1-pyrroline-5-carboxylate synthetase (P5CS) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 719 Score = 187 bits (475), Expect = 3e-47 Identities = 109/297 (36%), Positives = 169/297 (56%), Gaps = 5/297 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP++ S LI TY + FG KSR+G GGM +K KAA +A GI V+I G Sbjct: 202 PPSDPRSKLISTYVKEKHQGEITFGDKSRLGRGGMTAKVKAAVYAAYAGIPVIIASGKAT 261 Query: 197 NALLEIMHGKKVGTFFTLTPQ-----EDNQVELQAELARKASLELFQSTSNQRANAIRKL 361 + +++++ G+ VGT F ++ V A AR++S L +S +R + + Sbjct: 262 DNIIKVIDGQCVGTLFHKDAHLWVQVKETGVRDMAVAARESSRRLQAVSSEERKKILLDI 321 Query: 362 ADLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLN 541 AD L + +IL N+ D A+Y D ++ + Sbjct: 322 ADALEANEEKILAENEADVAAAQYAGYDRSLVARLAMNPDKISSLAKSIRVLADMEEPIG 381 Query: 542 RVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNS 721 R+L++TE++D LIL++ + P+GVLL++FESRPD L Q+ASLAI SGNG+LLKGG EA S Sbjct: 382 RILKRTEIADGLILEKTSCPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEAKRS 441 Query: 722 NKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 N L K++ A+ + + + LV+ R++I +LL+L+ IDLVIPRGS++++++IK Sbjct: 442 NAILHKVITSAIPDK-VGEKLIGLVTSRDEIPDLLKLDDVIDLVIPRGSNKLVSQIK 497
>sp|O04226|P5CS_ORYSA Delta 1-pyrroline-5-carboxylate synthetase (P5CS) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 716 Score = 184 bits (468), Expect = 2e-46 Identities = 108/297 (36%), Positives = 166/297 (55%), Gaps = 5/297 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP+E S +I TY + FG KSRVG GGM +K KAA A G VVI G Sbjct: 205 PPSEPSSKIIHTYIKEKHQQEITFGDKSRVGRGGMTAKVKAAVLASNSGTPVVITSGFEN 264 Query: 197 NALLEIMHGKKVGTFFTLTPQ-----EDNQVELQAELARKASLELFQSTSNQRANAIRKL 361 ++L+++HG+K+GT F +D A AR S L +S +R + + Sbjct: 265 RSILKVLHGEKIGTLFHKNANLWESSKDVSTREMAVAARDCSRHLQNLSSEERKKILLDV 324 Query: 362 ADLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLN 541 AD L ++ I N+ D A+ + + + + +N Sbjct: 325 ADALEANEDLIRSENEADVAAAQVAGYEKPLVARLTIKPGKIASLAKSIRTLANMEDPIN 384 Query: 542 RVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNS 721 ++L+KTE++D+L+L++ + P+GVLL++FESRPD L Q+ASLAI SGNG+LLKGG EA S Sbjct: 385 QILKKTEVADDLVLEKTSCPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEAIRS 444 Query: 722 NKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 N L K++ A+ + + + LV+ R++I +LL+L+ IDLV PRGS++++++IK Sbjct: 445 NTILHKVITDAI-PRNVGEKLIGLVTTRDEIADLLKLDDVIDLVTPRGSNKLVSQIK 500
>sp|O04015|P5CS_ACTCH Delta 1-pyrroline-5-carboxylate synthetase (P5CS) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 717 Score = 183 bits (465), Expect = 5e-46 Identities = 109/297 (36%), Positives = 167/297 (56%), Gaps = 5/297 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP++ S LI TY + FG KSRVG GGM +K KAA +A GI VVI G Sbjct: 205 PPSDPQSKLIHTYIKEMFEGLITFGDKSRVGRGGMTAKVKAAVYAAHAGIPVVITSGYAT 264 Query: 197 NALLEIMHGKKVGTFFTLTPQE-----DNQVELQAELARKASLELFQSTSNQRANAIRKL 361 N +++++ G+++GT F Q+ D A AR++S L + R+ + + Sbjct: 265 NNIIKVLQGERIGTLFHRDAQKWAPVGDVGARDMAVAARESSRRLQAMSPQDRSKILLDV 324 Query: 362 ADLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLN 541 AD L + I I N+ D A+ + ++ + + Sbjct: 325 ADALEANEKLIRIENEADLAAAQQAGYEKSLISRLALKSGKISSLAKSIRVLANMEEPIG 384 Query: 542 RVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNS 721 VL++TE++D L+L++ + P+GVLL+IFESRPD L Q+ASLAI SGNG++LKGG EA S Sbjct: 385 HVLKRTEITDGLVLEKTSSPLGVLLIIFESRPDALVQIASLAIRSGNGLVLKGGKEAKRS 444 Query: 722 NKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 N L K++ A+ + + + LV+ RE+I +LL+L+ IDLVIPRGS++++++IK Sbjct: 445 NAILHKVITSAI-PENVGPRLIGLVTSREEIPDLLKLDDVIDLVIPRGSNKLVSQIK 500
>sp|Q96480|P5CS_LYCES Delta 1-pyrroline-5-carboxylate synthetase (P5CS) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 717 Score = 180 bits (457), Expect = 4e-45 Identities = 106/297 (35%), Positives = 163/297 (54%), Gaps = 5/297 (1%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP + S LI TY + FG KSRVG GGM +K KAA +A GI VVI G Sbjct: 205 PPRDPDSKLIYTYIKEIHERVITFGDKSRVGRGGMTAKVKAAMYAAYAGIPVVITSGFAT 264 Query: 197 NALLEIMHGKKVGTFFTLTPQE-----DNQVELQAELARKASLELFQSTSNQRANAIRKL 361 + +++++HG+++GT F + + A AR S L +S +R+ ++ + Sbjct: 265 DNIIKVLHGERIGTLFHCDANKWASIGETDAREMAVAARACSRRLQALSSQERSKILQDI 324 Query: 362 ADLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLLN 541 AD L + IL N+ D A+ + ++ + L Sbjct: 325 ADALEANEKAILAENEADVVAAQQAGYEKSLISRLALNPGKISSLANSVRVLSNMDEPLG 384 Query: 542 RVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYNS 721 L++TE++D IL++ + P+GV+L+IFESRPD L Q+ASLA+ SGNG++LKGG EA S Sbjct: 385 HTLKRTEIADGFILEKSSSPLGVVLIIFESRPDALVQIASLAVRSGNGLMLKGGKEAKRS 444 Query: 722 NKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 N L K++ A+ + + LV+ RE+I LL+L+ IDLVIPRGS++++++IK Sbjct: 445 NAILHKVITSAI-PVSVGERLIGLVTSREEIPELLKLDDVIDLVIPRGSNKLVSQIK 500
>sp|P32296|P5CS_VIGAC Delta 1-pyrroline-5-carboxylate synthetase (P5CS) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 671 Score = 180 bits (456), Expect = 5e-45 Identities = 114/300 (38%), Positives = 166/300 (55%), Gaps = 8/300 (2%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP++ S LI TY + + FG KSRVG GGM +K KAA A GI VVI G Sbjct: 206 PPSDPHSKLIYTYNKEKHQNEITFGDKSRVGRGGMTAKVKAAVHAAEAGIPVVITSGFAP 265 Query: 197 NALLEIMHGKKVGTFFTLTPQEDNQVE--------LQAELARKASLELFQSTSNQRANAI 352 ++ ++ G+++GT F E QV+ + A R+ S Q N+ + Sbjct: 266 ENIINVLQGQRIGTLFHKDAHEWAQVKEVDAREMAVAAGNVREGSRRYLQRKGNK---IL 322 Query: 353 RKLADLLIEQQNEILIANDEDFRLAKYDLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHN 532 K+AD L + I I N+ D A+ + +I + + Sbjct: 323 LKIADALEANEKIIRIENEADVTAAQEAGYEKSLVARLALKPGKIASLANNMRIIANMED 382 Query: 533 LLNRVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEA 712 + RVL++TELSD LIL++ + P+GVLL++FESRPD L Q+ASLAI SGNG+LLKGG EA Sbjct: 383 PIGRVLKRTELSDGLILEKTSSPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEA 442 Query: 713 YNSNKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 SN L K++ +A+ + + LV+ RE+I LL+L+ IDLVIPRGS++++++IK Sbjct: 443 KRSNAILHKVIIEAI-PDNVGGKLIGLVTSREEIPELLKLDDVIDLVIPRGSNKLVSQIK 501
>sp|P54887|P5CS1_ARATH Delta 1-pyrroline-5-carboxylate synthetase A (P5CS A) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 717 Score = 180 bits (456), Expect = 5e-45 Identities = 112/298 (37%), Positives = 168/298 (56%), Gaps = 6/298 (2%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP++ S LI T+ + FG KSR+G GGM +K KAA A GI V+I G Sbjct: 205 PPSDPNSKLIHTFVKEKHQDEITFGDKSRLGRGGMTAKVKAAVNAAYAGIPVIITSGYSA 264 Query: 197 NALLEIMHGKKVGTFF-----TLTPQEDNQVELQAELARKASLELFQSTSNQRANAIRKL 361 + +++ G +VGT F P D+ A AR++S +L +S R + + Sbjct: 265 ENIDKVLRGLRVGTLFHQDARLWAPITDSNARDMAVAARESSRKLQALSSEDRKKILLDI 324 Query: 362 ADLLIEQQNEILIANDEDFRLAKY-DLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLL 538 AD L I N+ D A+ L+++M ++AD + + Sbjct: 325 ADALEANVTTIKAENELDVASAQEAGLEESMVARLVMTPGKISSLAASVRKLADM-EDPI 383 Query: 539 NRVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYN 718 RVL+KTE++D L+L++ + P+GVLL++FESRPD L Q+ASLAI SGNG+LLKGG EA Sbjct: 384 GRVLKKTEVADGLVLEKTSSPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEARR 443 Query: 719 SNKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 SN L K++ A+ + + + LV+ RE+I +LL+L+ IDLVIPRGS++++ +IK Sbjct: 444 SNAILHKVITDAI-PETVGGKLIGLVTSREEIPDLLKLDDVIDLVIPRGSNKLVTQIK 500
>sp|P54888|P5CS2_ARATH Delta 1-pyrroline-5-carboxylate synthetase B (P5CS B) [Includes: Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Gamma-glutamyl phosphate reductase (GPR) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)] Length = 726 Score = 176 bits (445), Expect = 1e-43 Identities = 109/298 (36%), Positives = 169/298 (56%), Gaps = 6/298 (2%) Frame = +2 Query: 17 PPNEEGSVLIDTYCTTTVNSTVEFGGKSRVGTGGMESKFKAAEWALTQGISVVICKGTHE 196 PP++ S LI T+ + FG KS++G GGM +K KAA A G+ V+I G Sbjct: 205 PPSDSTSKLIHTFIKEKHQDEITFGEKSKLGRGGMTAKVKAAVNAAYGGVPVIITSGYAA 264 Query: 197 NALLEIMHGKKVGTFF-----TLTPQEDNQVELQAELARKASLELFQSTSNQRANAIRKL 361 + +++ G +VGT F P D A AR++S +L +S R + + Sbjct: 265 ENISKVLRGLRVGTLFHQDAHLWAPVVDTTSRDMAVAARESSRKLQALSSEDRKQILHDI 324 Query: 362 ADLLIEQQNEILIANDEDFRLAKY-DLDDNMXXXXXXXXXXXXXXXXXXNQIADSCHNLL 538 A+ L + I ND D A+ ++++ Q+A+ + + Sbjct: 325 ANALEVNEKTIKAENDLDVAAAQEAGYEESLVARLVMKPGKISSLAASVRQLAEM-EDPI 383 Query: 539 NRVLRKTELSDNLILQEITIPIGVLLVIFESRPDCLPQVASLAIASGNGVLLKGGSEAYN 718 RVL+KT+++D+LIL++ + PIGVLL++FESRPD L Q+ASLAI SGNG+LLKGG EA Sbjct: 384 GRVLKKTQVADDLILEKTSSPIGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEARR 443 Query: 719 SNKYLFKLVKQALESQGLNSDAVNLVSKREDIQNLLQLNKYIDLVIPRGSSQMINKIK 892 SN L K++ A+ + + + LV+ RE+I +LL+L+ IDLVIPRGS++++++IK Sbjct: 444 SNAILHKVITDAI-PETVGGKLIGLVTSREEIPDLLKLDDVIDLVIPRGSNKLVSQIK 500
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,737,072 Number of Sequences: 369166 Number of extensions: 1693228 Number of successful extensions: 5003 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4711 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4855 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8934348180 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)