Planaria EST Database


DrC_01539

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01539
         (656 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P28829|BYR2_SCHPO  Protein kinase byr2 (Protein kinase st...    71   2e-12
sp|Q10056|SHK2_SCHPO  Serine/threonine-protein kinase shk2         70   6e-12
sp|P50527|SHK1_SCHPO  Serine/threonine-protein kinase pak1/shk1    69   1e-11
sp|Q61083|M3K2_MOUSE  Mitogen-activated protein kinase kinas...    68   2e-11
sp|Q64303|PAK2_RAT  Serine/threonine-protein kinase PAK 2 (p...    67   4e-11
sp|Q8CIN4|PAK2_MOUSE  Serine/threonine-protein kinase PAK 2 ...    67   4e-11
sp|Q99759|M3K3_HUMAN  Mitogen-activated protein kinase kinas...    67   4e-11
sp|Q13177|PAK2_HUMAN  Serine/threonine-protein kinase PAK 2 ...    67   4e-11
sp|Q29502|PAK2_RABIT  Serine/threonine-protein kinase PAK 2 ...    67   4e-11
sp|Q61084|M3K3_MOUSE  Mitogen-activated protein kinase kinas...    67   5e-11
>sp|P28829|BYR2_SCHPO Protein kinase byr2 (Protein kinase ste8) (MAPK kinase kinase)
           (MAPKKK)
          Length = 659

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 45/132 (34%), Positives = 73/132 (55%), Gaps = 1/132 (0%)
 Frame = +3

Query: 141 GSSVLVDNEDNIKLTNFHLSKYL-FNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGL 317
           G+++LVDN+  IK+++F +SK L  N+T  +     P    + S  W+APEV++   +  
Sbjct: 525 GANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPS--FQGSSFWMAPEVVKQTMHTE 582

Query: 318 KSDIWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIHYNRNLIPGYFHDFLDRCLRV 497
           K+DIWSL   V+EM T   PYP  + ++A  RI  EN +    + I     DFL++   +
Sbjct: 583 KTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRI-GENILPEFPSNISSSAIDFLEKTFAI 641

Query: 498 PHWERPSAKQCI 533
               RP+A + +
Sbjct: 642 DCNLRPTASELL 653
>sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2
          Length = 589

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 42/131 (32%), Positives = 68/131 (51%), Gaps = 2/131 (1%)
 Frame = +3

Query: 147 SVLVDNEDNIKLTNFHLSKYLFNATMDQL-LEGIPGSRIETSKCWLAPEVLRNDPYGLKS 323
           +VL+DN  NIK+T+F     L N T  ++ + G P         W+APEV++ + YG K 
Sbjct: 439 NVLLDNSGNIKITDFGFCARLSNRTNKRVTMVGTP--------YWMAPEVVKQNEYGTKV 490

Query: 324 DIWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIHYNR-NLIPGYFHDFLDRCLRVP 500
           DIWSL + ++EM  ++ PY   + +RA + I         + NL+      FL+ CL + 
Sbjct: 491 DIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTPTLKKPNLVSKNLKSFLNSCLTID 550

Query: 501 HWERPSAKQCI 533
              R +A + +
Sbjct: 551 TIFRATAAELL 561
>sp|P50527|SHK1_SCHPO Serine/threonine-protein kinase pak1/shk1
          Length = 658

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 2/132 (1%)
 Frame = +3

Query: 147 SVLVDNEDNIKLTNFHLSKYL-FNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLKS 323
           ++L+  + +IKLT+F     +  N T    + G P         W+APEV+    YG K 
Sbjct: 510 NILLSLQGDIKLTDFGFCAQIDSNMTKRTTMVGTP--------YWMAPEVVTRKEYGFKV 561

Query: 324 DIWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIHYNR-NLIPGYFHDFLDRCLRVP 500
           D+WSL +  +EM   + PY   N LRA + I        +R  L+   FHDFL + L V 
Sbjct: 562 DVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPELLSSVFHDFLSKSLTVN 621

Query: 501 HWERPSAKQCIQ 536
             +RPS+ + ++
Sbjct: 622 PKQRPSSGELLR 633
>sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase kinase 2 (MAPK/ERK kinase
           kinase 2) (MEK kinase 2) (MEKK 2)
          Length = 619

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 44/132 (33%), Positives = 68/132 (51%)
 Frame = +3

Query: 141 GSSVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLK 320
           G+++L D+  NIKL +F  SK L        L G     +  +  W++PEV+  + YG K
Sbjct: 486 GANILRDSTGNIKLGDFGASKRLQTIC----LSGTGMKSVTGTPYWMSPEVISGEGYGRK 541

Query: 321 SDIWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIHYNRNLIPGYFHDFLDRCLRVP 500
           +DIWS+A TV+EM T   P+ E   + A  +I  +         +  Y  DFL R + V 
Sbjct: 542 ADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKR-IFVE 600

Query: 501 HWERPSAKQCIQ 536
              RPSA++ ++
Sbjct: 601 AKLRPSAEELLR 612
>sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
           (PAK-2) (Gamma-PAK) (p62-PAK)
          Length = 524

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 45/131 (34%), Positives = 66/131 (50%), Gaps = 1/131 (0%)
 Frame = +3

Query: 147 SVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLKSD 326
           +VL+  E ++KLT+F     +   T +Q       S +  +  W+APEV+    YG K D
Sbjct: 373 NVLLGMEGSVKLTDFGFCAQI---TPEQSKR----STMVGTPYWMAPEVVTRKAYGPKVD 425

Query: 327 IWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIH-YNRNLIPGYFHDFLDRCLRVPH 503
           IWSL +  +EM   + PY   N LRA + I         N   +   F DFL+RCL +  
Sbjct: 426 IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDV 485

Query: 504 WERPSAKQCIQ 536
            +R SAK+ +Q
Sbjct: 486 EKRGSAKELLQ 496
>sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
           (PAK-2)
          Length = 524

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 45/131 (34%), Positives = 66/131 (50%), Gaps = 1/131 (0%)
 Frame = +3

Query: 147 SVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLKSD 326
           +VL+  E ++KLT+F     +   T +Q       S +  +  W+APEV+    YG K D
Sbjct: 373 NVLLGMEGSVKLTDFGFCAQI---TPEQSKR----STMVGTPYWMAPEVVTRKAYGPKVD 425

Query: 327 IWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIH-YNRNLIPGYFHDFLDRCLRVPH 503
           IWSL +  +EM   + PY   N LRA + I         N   +   F DFL+RCL +  
Sbjct: 426 IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDV 485

Query: 504 WERPSAKQCIQ 536
            +R SAK+ +Q
Sbjct: 486 EKRGSAKELLQ 496
>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 (MAPK/ERK kinase
           kinase 3) (MEK kinase 3) (MEKK 3)
          Length = 626

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 42/131 (32%), Positives = 68/131 (51%)
 Frame = +3

Query: 141 GSSVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLK 320
           G+++L D+  N+KL +F  SK L    M     G     +  +  W++PEV+  + YG K
Sbjct: 492 GANILRDSAGNVKLGDFGASKRLQTICMS----GTGMRSVTGTPYWMSPEVISGEGYGRK 547

Query: 321 SDIWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIHYNRNLIPGYFHDFLDRCLRVP 500
           +D+WSL  TV+EM T   P+ E   + A  +I  +       + I  +  DFL R + V 
Sbjct: 548 ADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRR-IFVE 606

Query: 501 HWERPSAKQCI 533
             +RPSA++ +
Sbjct: 607 ARQRPSAEELL 617
>sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
           (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase)
          Length = 524

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 45/131 (34%), Positives = 66/131 (50%), Gaps = 1/131 (0%)
 Frame = +3

Query: 147 SVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLKSD 326
           +VL+  E ++KLT+F     +   T +Q       S +  +  W+APEV+    YG K D
Sbjct: 373 NVLLGMEGSVKLTDFGFCAQI---TPEQSKR----STMVGTPYWMAPEVVTRKAYGPKVD 425

Query: 327 IWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIH-YNRNLIPGYFHDFLDRCLRVPH 503
           IWSL +  +EM   + PY   N LRA + I         N   +   F DFL+RCL +  
Sbjct: 426 IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDV 485

Query: 504 WERPSAKQCIQ 536
            +R SAK+ +Q
Sbjct: 486 EKRGSAKELLQ 496
>sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 (p21-activated kinase 2)
           (PAK-2) (Gamma-PAK) (p21-activated protein kinase I)
           (PAKI)
          Length = 524

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 45/131 (34%), Positives = 66/131 (50%), Gaps = 1/131 (0%)
 Frame = +3

Query: 147 SVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLKSD 326
           +VL+  E ++KLT+F     +   T +Q       S +  +  W+APEV+    YG K D
Sbjct: 373 NVLLGMEGSVKLTDFGFCAQI---TPEQSKR----STMVGTPYWMAPEVVTRKAYGPKVD 425

Query: 327 IWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIH-YNRNLIPGYFHDFLDRCLRVPH 503
           IWSL +  +EM   + PY   N LRA + I         N   +   F DFL+RCL +  
Sbjct: 426 IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDV 485

Query: 504 WERPSAKQCIQ 536
            +R SAK+ +Q
Sbjct: 486 EKRGSAKELLQ 496
>sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase kinase 3 (MAPK/ERK kinase
           kinase 3) (MEK kinase 3) (MEKK 3)
          Length = 626

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 42/131 (32%), Positives = 68/131 (51%)
 Frame = +3

Query: 141 GSSVLVDNEDNIKLTNFHLSKYLFNATMDQLLEGIPGSRIETSKCWLAPEVLRNDPYGLK 320
           G+++L D+  N+KL +F  SK L    M     G     +  +  W++PEV+  + YG K
Sbjct: 492 GANILRDSAGNVKLGDFGASKRLQTICMS----GTGIRSVTGTPYWMSPEVISGEGYGRK 547

Query: 321 SDIWSLAVTVLEMFTHDRPYPEMNVLRATHRIVYENAIHYNRNLIPGYFHDFLDRCLRVP 500
           +D+WSL  TV+EM T   P+ E   + A  +I  +       + I  +  DFL R + V 
Sbjct: 548 ADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFLRR-IFVE 606

Query: 501 HWERPSAKQCI 533
             +RPSA++ +
Sbjct: 607 ARQRPSAEELL 617
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,002,468
Number of Sequences: 369166
Number of extensions: 1456758
Number of successful extensions: 5396
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4592
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5234
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5462583840
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)