Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= DrC_01491
(939 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 88 3e-17
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 86 1e-16
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 86 2e-16
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 84 4e-16
sp|P81013|GRN1_CYPCA Granulin-1 55 2e-07
sp|P81015|GRN3_CYPCA Granulin-3 54 6e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 6e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 2e-05
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 49 2e-05
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 9e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 88.2 bits (217), Expect = 3e-17
Identities = 44/121 (36%), Positives = 58/121 (47%), Gaps = 2/121 (1%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
A+CC D LHCCP+ T CDL+ +CI + + + P Y V
Sbjct: 235 AICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDLMTKLPGYPVNE------ 278
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTGG 844
+K + +CPDG TCC + TG +GCCPF+ VCC D CC G+ C TG
Sbjct: 279 -VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGT 331
Query: 845 C 847
C
Sbjct: 332 C 332
Score = 77.4 bits (189), Expect = 5e-14
Identities = 39/115 (33%), Positives = 53/115 (46%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 667
+A CC D++HCCP G +CDLV+ RCI + P+++ P R+
Sbjct: 153 QASCCEDRVHCCPHGASCDLVHTRCISPTGTH---PLLKKF-------PAQRTNRAVASF 202
Query: 668 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
++ K CPD TCC + TG YGCCP +CC D CC C
Sbjct: 203 SVVCPDAKTQCPDDS------TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 75.9 bits (185), Expect = 2e-13
Identities = 41/118 (34%), Positives = 53/118 (44%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
AVCC D+ HCCP G TC++ + C E +V+ S F
Sbjct: 469 AVCCEDRQHCCPAGYTCNVKARTC---------------------EKDAGSVQPSMDLTF 507
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
K+G+ C G C Q+CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 508 GSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 73.9 bits (180), Expect = 6e-13
Identities = 37/121 (30%), Positives = 55/121 (45%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F KAVCC D +HCCP G C C ++ P ++ + +A + P + ++ +
Sbjct: 306 FTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKV-TASLSLPDPQILKNDV 361
Query: 662 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTG 841
C D C TCC + +G +GCCP VCC D + CC G+ C+
Sbjct: 362 P-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDE 410
Query: 842 G 844
G
Sbjct: 411 G 411
Score = 60.8 bits (146), Expect = 5e-09
Identities = 36/115 (31%), Positives = 47/115 (40%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 667
+AVCC D HCCP+G C ++ + D K V ++TL
Sbjct: 390 EAVCCLDHQHCCPQGFKC--------------MDEGYCQKGDRMVAGLEKMPVRQTTL-- 433
Query: 668 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
++ GD C C QTCC G + CC VCC D + CC GY C
Sbjct: 434 --LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
Score = 60.5 bits (145), Expect = 7e-09
Identities = 34/117 (29%), Positives = 42/117 (35%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F + V C D HCCP G C K C S+ + ++ P
Sbjct: 86 FSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL----------GAVQCP--------- 126
Query: 662 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
G + CPD TCC+M G +GCCP CC D CC G C
Sbjct: 127 -------GSQFECPDSA------TCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 51.6 bits (122), Expect = 3e-06
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +2
Query: 689 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 35.4 bits (80), Expect = 0.23
Identities = 12/30 (40%), Positives = 16/30 (53%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQ 571
+ K VCC D HCCP G C +C+ +
Sbjct: 541 YVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 86.3 bits (212), Expect = 1e-16
Identities = 41/116 (35%), Positives = 57/116 (49%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
A CC D LHCCP+ T CDL+ +C+ + N + + P +TV
Sbjct: 237 ATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------LLTKLPAHTVGD------ 281
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 838
+K + +CPDG TCC + +G +GCCPF+ VCC D CC G+ C T
Sbjct: 282 -VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 80.5 bits (197), Expect = 6e-15
Identities = 42/127 (33%), Positives = 54/127 (42%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F +AVCC D +HCCP G TCD C P + P +E + ++R
Sbjct: 309 FTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQALKRDV- 364
Query: 662 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTG 841
C + C TCC + +G +GCCP VCC D + CC GY CV
Sbjct: 365 -----------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAE 413
Query: 842 GCA*LGS 862
G GS
Sbjct: 414 GQCQRGS 420
Score = 75.5 bits (184), Expect = 2e-13
Identities = 41/116 (35%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 667
+A CC D++HCCP G CDLV+ RCI + T AK + P R+
Sbjct: 154 QASCCEDRVHCCPHGAFCDLVHTRCITPTG---------THPLAK-KLPAQRTNRAVALS 203
Query: 668 FMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
+ D ++ CPDG TCC + +G YGCCP CC D CC C
Sbjct: 204 SSVMCPDARSRCPDG------STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
Score = 73.6 bits (179), Expect = 8e-13
Identities = 38/119 (31%), Positives = 51/119 (42%), Gaps = 1/119 (0%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
AVCC D+ HCCP G TC++ + C E + + +T
Sbjct: 472 AVCCEDRQHCCPAGYTCNVKARSC---------------------EKEVVSAQPATFLAR 510
Query: 671 MIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
+G K+ C +G C QTCC + CCP+ GVCC D R CC G+ C G
Sbjct: 511 SPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 63.5 bits (153), Expect = 8e-10
Identities = 34/118 (28%), Positives = 41/118 (34%), Gaps = 1/118 (0%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F +AV CGD HCCP G C + C +S +
Sbjct: 86 FPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI--------------------- 124
Query: 662 REFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
CPD +C TCC+M G +GCCP CC D CC G C
Sbjct: 125 -----------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 63.5 bits (153), Expect = 8e-10
Identities = 38/115 (33%), Positives = 48/115 (41%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 667
+AVCC D HCCP+G TC + +C S I + + P S R+
Sbjct: 393 EAVCCSDHQHCCPQGYTC-VAEGQCQRGSE----------IVAGLEKMPARRASLSHPRD 441
Query: 668 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
I +CP G QTCC G + CC VCC D + CC GY C
Sbjct: 442 --IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 43.9 bits (102), Expect = 7e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +2
Query: 698 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 35.0 bits (79), Expect = 0.31
Identities = 11/28 (39%), Positives = 16/28 (57%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQ 571
+ VCC D+ HCCP G C +C+ +
Sbjct: 548 QGVCCADRRHCCPAGFRCAARGTKCLRR 575
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 85.9 bits (211), Expect = 2e-16
Identities = 42/116 (36%), Positives = 59/116 (50%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
A+CC D LHCCP+ T CDL+ +C+ ++ T D + P Y V+
Sbjct: 236 AICCSDHLHCCPQDTVCDLIQSKCLSKNY---------TTDLLT-KLPGYPVKE------ 279
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 838
+K + +CP+G TCC + TG +GCCPF+ VCC D CC G+ C T
Sbjct: 280 -VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 79.3 bits (194), Expect = 1e-14
Identities = 42/118 (35%), Positives = 57/118 (48%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 470 AVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP------------------ 510
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
K+G+ C +G C QTCC G + CCP+ GVCC D R CC G+HC G
Sbjct: 511 --KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 77.4 bits (189), Expect = 5e-14
Identities = 39/116 (33%), Positives = 52/116 (44%), Gaps = 1/116 (0%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 667
+A CC D++HCCP G +CDLV+ RC+ + + + P R+
Sbjct: 153 QASCCEDRVHCCPHGASCDLVHTRCVSPTGT----------HTLLKKFPAQKTNRAVSLP 202
Query: 668 FMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
F + D K CPD TCC + TG YGCCP +CC D CC C
Sbjct: 203 FSVVCPDAKTQCPDDS------TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252
Score = 76.3 bits (186), Expect = 1e-13
Identities = 38/121 (31%), Positives = 52/121 (42%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F KAVCC D +HCCP G C H E +++ K+ P + L
Sbjct: 307 FAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLRLPDPQIL 358
Query: 662 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTG 841
+ C D +C TCC + +G +GCCP VCC D + CC G+ C+
Sbjct: 359 KS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQ 411
Query: 842 G 844
G
Sbjct: 412 G 412
Score = 71.6 bits (174), Expect = 3e-12
Identities = 37/117 (31%), Positives = 45/117 (38%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F K V CGD HCCP+G C K C S+ P+ ++ P
Sbjct: 86 FSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------GAVQCP--------- 126
Query: 662 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
G + CPD TCC+M G +GCCP CC D CC G C
Sbjct: 127 -------GSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/116 (33%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 667
+AVCC D HCCP+G TC L C K +T +E+ R+
Sbjct: 391 EAVCCSDNQHCCPQGFTC-LAQGYC------------------QKGDTMVAGLEKIPARQ 431
Query: 668 FM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
++IGD C C QTCC G + CC VCC D + CC GY C
Sbjct: 432 TTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
Score = 51.2 bits (121), Expect = 4e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +2
Query: 695 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 35.8 bits (81), Expect = 0.18
Identities = 12/30 (40%), Positives = 16/30 (53%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQ 571
+ K VCC D HCCP G C +C+ +
Sbjct: 542 YLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 84.3 bits (207), Expect = 4e-16
Identities = 40/116 (34%), Positives = 57/116 (49%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
A+CC D LHCCP+ T CDL RC+ Q+ + + P +TV +
Sbjct: 237 AICCSDHLHCCPQDTVCDLRQSRCLSQNKAK----------TLLTKLPSWTV-------W 279
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 838
++ + +CP+G QTCC + +G +GCCPF VCC D CC + C T
Sbjct: 280 DVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 80.1 bits (196), Expect = 8e-15
Identities = 43/118 (36%), Positives = 54/118 (45%)
Frame = +2
Query: 491 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 670
AVCC D HCCP G TC++ + C + D A + P ST
Sbjct: 469 AVCCEDGQHCCPAGYTCNVKARSC------------EKAADGAHLAAP--LAVGSTGGVM 514
Query: 671 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
+ GD++ C D QTCC G + CCPF GVCC D R CC G+HC + G
Sbjct: 515 DVACGDRHFCHDE------QTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 77.0 bits (188), Expect = 7e-14
Identities = 43/121 (35%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWPVVETIDSAKIETPKYT--VER 652
+A CC D++HCCP G +CDLV+ RC+ + P+ + P T + TP + +
Sbjct: 140 QASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLP 199
Query: 653 STLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 829
+ L +I CPD QC TCCL+ +G YGCCP +CC D CC
Sbjct: 200 AALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTV 252
Query: 830 C 832
C
Sbjct: 253 C 253
Score = 59.7 bits (143), Expect = 1e-08
Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 1/118 (0%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F +A+ CGD HCCP G C CI + P + + + +
Sbjct: 72 FSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIHLLGAVQ------------- 111
Query: 662 REFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
CP G +C TCC M G +GCCP CC D CC G C
Sbjct: 112 ------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/104 (27%), Positives = 40/104 (38%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 661
F KAVCC D +HCCPE C C Q + W ++ P
Sbjct: 308 FPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPP 366
Query: 662 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 793
+ + +C + C CC + +G +GCCP S G C
Sbjct: 367 SP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
Score = 46.6 bits (109), Expect = 1e-04
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +2
Query: 695 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 844
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/118 (27%), Positives = 46/118 (38%), Gaps = 5/118 (4%)
Frame = +2
Query: 494 VCC---GDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERST 658
+CC + CCP EG C + +RC V + + K+ ++ ++T
Sbjct: 389 ICCRLASGEWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHLMSLSQTT 437
Query: 659 LREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
+G C C QTCC G + CC VCC D + CC GY C
Sbjct: 438 ------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 43.9 bits (102), Expect = 7e-04
Identities = 15/32 (46%), Positives = 20/32 (62%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 577
F + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 543 FHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 2e-07
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +2
Query: 698 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 32.7 bits (73), Expect = 1.5
Identities = 11/28 (39%), Positives = 14/28 (50%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCI 565
F CC D +HCC G CD + C+
Sbjct: 29 FSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 6e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +2
Query: 698 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 31.2 bits (69), Expect = 4.4
Identities = 11/28 (39%), Positives = 13/28 (46%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCI 565
F CC D HCC G CD + C+
Sbjct: 29 FLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 53.9 bits (128), Expect = 6e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +2
Query: 698 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 826
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
Score = 31.6 bits (70), Expect = 3.4
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEG 532
+ + VCC DQ HCCP G
Sbjct: 29 YSQGVCCADQRHCCPVG 45
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 2e-05
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 716 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 31.6 bits (70), Expect = 3.4
Identities = 11/28 (39%), Positives = 13/28 (46%)
Frame = +2
Query: 482 FFKAVCCGDQLHCCPEGTTCDLVNKRCI 565
F CC D HCC G CD + C+
Sbjct: 29 FLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 48.9 bits (115), Expect = 2e-05
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 716 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 832
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
Score = 42.7 bits (99), Expect = 0.001
Identities = 15/26 (57%), Positives = 19/26 (73%)
Frame = +2
Query: 488 KAVCCGDQLHCCPEGTTCDLVNKRCI 565
+ VCC D +HCCP GT CD ++RCI
Sbjct: 28 EGVCCLDGIHCCPSGTVCDEDHRRCI 53
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 9e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +2
Query: 686 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 826
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,760,851
Number of Sequences: 369166
Number of extensions: 2101173
Number of successful extensions: 5844
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5317
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5772
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9702894260
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)